Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]oxypropyl]thiophene-2-sulfonamide
    Show/Hide
 PubChem ID
CID: 9810400
SID: 14766422
Canonical SMILES
COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCCNS(=O)(=O)c1cccs1)-c1ncccn1
    Show/Hide
Compound Formula C32H34N6O7S3
Compound Structure
Protein Name
 Protein Info 
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Endothelin receptor
Uniprot ID
P25101
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 86 nM
   TI
   LI
   LO
   TS