Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[6-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]butane-1-sulfonamide
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 PubChem ID
CID: 71451528
SID: 163485748
Canonical SMILES
CCCCS(=O)(=O)Nc1nc(nc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC)-c1ncccn1
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Compound Formula C25H26BrN7O6S
Compound Structure
Protein Name
 Protein Info 
Endothelin-1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P25101
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.3 nM