Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-6-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-6-phenyl-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulene-1-carboxylic acid
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 PubChem ID
CID: 11156301
SID: 16235121
Canonical SMILES
Cc1cc(C)nc(O[C@H](C(=O)O)[C@@]2(c3ccccc3)NCc3nnc(CC(=O)O)n3-c3ccccc32)n1
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Compound Formula C26H24N6O5
Compound Structure
Protein Name
 Protein Info 
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P25101
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 58.8 nM
   TI
   LI
   LO
   TS