Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[5-(2-methoxyphenoxy)-6-[(5-methylpyridin-2-yl)sulfonylamino]-2-morpholin-4-ylpyrimidin-4-yl]oxybut-2-ynyl N-pyridin-2-ylcarbamate
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 PubChem ID
CID: 10211781
SID: 15209875
Canonical SMILES
COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCOC(=O)Nc1ccccn1)N1CCOCC1
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Compound Formula C31H31N7O8S
Compound Structure
Protein Name
 Protein Info 
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P25101
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS