Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3,3-Bis-(4-chloro-phenyl)-2-(4,6-dimethoxy-pyrimidin-2-yloxy)-3-methoxy-propionic acid
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 PubChem ID
CID: 10552683
SID: 15579752
Canonical SMILES
COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)n1
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Compound Formula C22H20Cl2N2O6
Compound Structure
Protein Name
 Protein Info 
Endothelin-1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Endothelin receptor
Uniprot ID
P25101
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 245 nM
   TI
   LI
   LO
   TS