Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-(4,6-Dimethoxy-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid
    Show/Hide
 PubChem ID
CID: 11408654
SID: 16504333
Canonical SMILES
COc1cc(OC)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(C)c3ccccc23)c2ccccc2)n1
    Show/Hide
Compound Formula C24H24N4O6
Compound Structure
Protein Name
 Protein Info 
Endothelin-1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Endothelin receptor
Uniprot ID
P25101
Gene Name
EDNRA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 23.4 nM
   TI
   LI
   LO
   TS