| Compound ID |
Compound Name |
Compound Formula |
|
CP0521376
|
5-amino-8-chloro-N-(2,3-dihydro-1H-inden-2-yl)-7,12-dimethyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C20H18ClN5OS
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0384239
|
5-amino-8-chloro-N-(2,3-dihydro-1H-inden-2-yl)-7-methyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H16ClN5OS
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0384241
|
5-amino-N-[1-(3,4-difluorophenyl)azetidin-3-yl]-7-methyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H16F2N6OS
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0388123
|
6-fluoro-5-methyl-3-[1-(1-methyl-4-propoxycyclohexyl)piperidin-4-yl]-1H-benzimidazol-2-one
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|
C23H34FN3O2
|
1
|
| 1 |
EC50 = 12.59 nM
|
|
|
|
CP0384238
|
5-amino-8-chloro-N-cyclopropyl-7-methyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C13H12ClN5OS
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0521383
|
5-amino-N-(2,3-dihydro-1H-inden-2-yl)-7-methyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H17N5OS
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0045829
|
3-(1-cyclohexylpiperidin-4-yl)-1H-benzimidazol-2-one
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|
C18H25N3O
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0528098
|
5-amino-8-chloro-N-[(1S)-2,3-dihydro-1H-inden-1-yl]-7-methyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H16ClN5OS
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0488018
|
5-amino-8-chloro-N-cyclopropyl-7,12-dimethyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C14H14ClN5OS
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0384236
|
5-amino-N-[1-(2,3-difluorophenyl)azetidin-3-yl]-7-methyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H16F2N6OS
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0416347
|
CHEMBL1223804
Show/Hide
|
C23H34N2O2
|
1
|
| 1 |
EC50 = 31.62 nM
|
|
|
|
CP0544487
|
5-amino-N-(2,3-dihydro-1H-inden-2-yl)-7-methyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H17N5OS
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0372671
|
6-methyl-1-[1-(1-methyl-4-propoxycyclohexyl)piperidin-4-yl]-3H-indol-2-one
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|
C24H36N2O2
|
1
|
| 1 |
EC50 = 39.81 nM
|
|
|
|
CP0488021
|
5-amino-N-(2,3-dihydro-1H-inden-2-yl)-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C20H19N5OS
|
1
|
| 1 |
EC50 = 46 nM
|
|
|
|
CP0000324
|
2-acetoxyethyl(trimethyl)ammonium;bromide
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|
C7H16NO2+
|
2
|
| 1 |
EC50 = 48.8 nM
|
|
|
| 2 |
Ki = 8511.38 nM
|
|
|
|
CP0139207
|
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C23H24N2O4
|
4
|
| 1 |
EC50 = 54 nM
|
|
|
| 2 |
IC50 = 90.7 nM
|
|
|
| 3 |
IC50 > 1000 nM
|
|
|
| 4 |
Ki = 7.079 nM
|
|
|
|
CP0521378
|
5-amino-N-(6,7-dihydro-5H-cyclopenta[b]pyridin-6-yl)-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H18N6OS
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0339387
|
N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-1-methyltriazolo[4,5-h]quinazolin-6-amine
Show/Hide
|
C17H14Cl2N8
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0851174
|
1-(4-hydroxy-4,4-diphenylbutyl)-4-[1-(4-hydroxy-4,4-diphenylbutyl)-1-methylpiperidin-1-ium-4-yl]-1-methylpiperidin-1-ium diiodide
Show/Hide
|
C44H58I2N2O2
|
2
|
| 1 |
EC50 = 67 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0568565
|
[3-amino-8-(2-morpholin-4-ylethoxy)-5-thia-7-azatricyclo[7.3.0.02,6]dodeca-1(9),2(6),3,7-tetraen-4-yl]-pyridin-4-ylmethanone
Show/Hide
|
C22H24N4O3S
|
1
|
| 1 |
EC50 = 76 nM
|
|
|
|
CP0384242
|
5-amino-N-[(4-methoxyphenyl)methyl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H19N5O2S
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0528087
|
N-cyclobutyl-11,13-dimethyl-8-thia-5,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C16H17N3S
|
1
|
| 1 |
EC50 = 85 nM
|
|
|
|
CP0521384
|
5-amino-N-(6,7-dihydro-5H-cyclopenta[b]pyridin-6-yl)-7-methyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C18H16N6OS
|
1
|
| 1 |
EC50 = 86 nM
|
|
|
|
CP0384235
|
5-amino-N-[(4-methoxyphenyl)methyl]-7-methyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C18H17N5O2S
|
1
|
| 1 |
EC50 = 89 nM
|
|
|
|
CP0258633
|
4-amino-N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-3-methylbenzotriazole-5-carboxamide
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|
C16H15Cl2N7O
|
1
|
| 1 |
EC50 = 91 nM
|
|
|
|
CP0542260
|
5-amino-N-[(4-methoxyphenyl)methyl]-7-methyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C18H17N5O2S
|
1
|
| 1 |
EC50 = 95 nM
|
|
|
|
CP0388126
|
3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-6-fluoro-5-methyl-1,3-benzoxazol-2-one
Show/Hide
|
C22H31FN2O3
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0118955
|
5-amino-N-[1-(3,4-difluorophenyl)azetidin-3-yl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C20H18F2N6OS
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0528100
|
5-amino-N-cyclopropyl-7-methyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C13H13N5OS
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0452978
|
4-bromo-N-[(1R,2R)-2-hydroxy-6-[(1-methylpiperidin-2-ylidene)amino]-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C22H24BrN3O2
|
1
|
| 1 |
EC50 = 113 nM
|
|
|
|
CP0384741
|
4-bromo-N-[(1R,2R)-6-[[N-[(4-fluorophenyl)methyl]-C-methylcarbonimidoyl]amino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C25H23BrFN3O2
|
1
|
| 1 |
EC50 = 115 nM
|
|
|
|
CP0384240
|
5-amino-N-[(1S)-2,3-dihydro-1H-inden-1-yl]-7-methyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H17N5OS
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0521379
|
5-amino-N-[(1S)-2,3-dihydro-1H-inden-1-yl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C20H19N5OS
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0521381
|
5-amino-N-[1-(2-cyclopropylpyrimidin-5-yl)azetidin-3-yl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C21H22N8OS
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0578021
|
N-cyclopentyl-11,13-dimethyl-8-thia-5,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C17H19N3S
|
1
|
| 1 |
EC50 = 124 nM
|
|
|
|
CP0521200
|
4-amino-N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-2,3-dimethylindazole-5-carboxamide
Show/Hide
|
C18H18Cl2N6O
|
1
|
| 1 |
EC50 = 125 nM
|
|
|
|
CP0388125
|
CHEMBL1223807
Show/Hide
|
C21H30N2O3
|
1
|
| 1 |
EC50 = 125.89 nM
|
|
|
|
CP0521377
|
5-amino-N-cyclopropyl-7-methyl-3-thia-1,10-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C14H14N4OS
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0473135
|
N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide
Show/Hide
|
C17H16Cl2N6O
|
1
|
| 1 |
EC50 = 132 nM
|
|
|
|
CP0403993
|
4-amino-2,3-dimethyl-N-[1-[6-(trifluoromethyl)pyridin-3-yl]azetidin-3-yl]indazole-5-carboxamide
Show/Hide
|
C19H19F3N6O
|
1
|
| 1 |
EC50 = 137 nM
|
|
|
|
CP0851169
|
1-(4-hydroxy-4,4-diphenylbutyl)-4-[1-(4-hydroxy-4,4-diphenylbutyl)piperidin-1-ium-4-yl]piperidin-1-ium dichloride
Show/Hide
|
C42H54Cl2N2O2
|
1
|
| 1 |
EC50 = 138 nM
|
|
|
|
CP0259249
|
5-amino-N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H17Cl2N7OS
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0353671
|
5-amino-N-[1-(5-chloropyrazin-2-yl)azetidin-3-yl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C18H17ClN8OS
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0495332
|
6-(11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl)-2-oxa-6-azaspiro[3.3]heptane
Show/Hide
|
C16H16N4OS
|
1
|
| 1 |
EC50 = 144 nM
|
|
|
|
CP0125601
|
4-amino-N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-2,3-dimethylindazole-5-carboxamide
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|
C19H21ClN6O2
|
1
|
| 1 |
EC50 = 148 nM
|
|
|
|
CP0554120
|
11,13-dimethyl-N-[1-[5-(trifluoromethyl)pyrimidin-2-yl]azetidin-3-yl]-8-thia-5,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C20H17F3N6S
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0495323
|
11,13-dimethyl-6-(oxan-4-yl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
Show/Hide
|
C16H17N3OS
|
1
|
| 1 |
EC50 = 152 nM
|
|
|
|
CP0416476
|
4-amino-N-[1-(3-chloro-5-cyanopyridin-2-yl)azetidin-3-yl]-2,3-dimethylindazole-5-carboxamide
Show/Hide
|
C19H18ClN7O
|
1
|
| 1 |
EC50 = 158 nM
|
|
|
|
CP0372673
|
CHEMBL1223805
Show/Hide
|
C22H32N2O2
|
1
|
| 1 |
EC50 = 158.49 nM
|
|
|
|
CP0372676
|
CHEMBL1223862
Show/Hide
|
C22H32N2O4
|
1
|
| 1 |
EC50 = 158.49 nM
|
|
|
|
CP0530072
|
5-amino-N-[1-(6-chloro-2-methylpyrimidin-4-yl)azetidin-3-yl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H19ClN8OS
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0537031
|
5-amino-N-[(3-fluoro-4-methoxyphenyl)methyl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H18FN5O2S
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0552819
|
6-(azetidin-1-yl)-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
Show/Hide
|
C14H14N4S
|
1
|
| 1 |
EC50 = 172 nM
|
|
|
|
CP0372675
|
CHEMBL1223861
Show/Hide
|
C22H31FN2O3
|
1
|
| 1 |
EC50 = 199.53 nM
|
|
|
|
CP0406096
|
CHEMBL1223940
Show/Hide
|
C23H34N2O4
|
1
|
| 1 |
EC50 = 199.53 nM
|
|
|
|
CP0045827
|
3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
|
C17H23N3O2
|
1
|
| 1 |
EC50 = 199.53 nM
|
|
|
|
CP0488799
|
N,N,11,13-tetramethyl-8-thia-5,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C14H15N3S
|
1
|
| 1 |
EC50 = 202 nM
|
|
|
|
CP0049755
|
(R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino]-acetonitrile
Show/Hide
|
C10H15N3O
|
1
|
| 1 |
EC50 = 214 nM
|
|
|
|
CP0530071
|
5-amino-N-(6,7-dihydro-5H-cyclopenta[b]pyridin-6-yl)-7-methyl-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C18H16N6OS
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0444579
|
4-bromo-N-[(1R,2R)-6-[[N-[(2-fluorophenyl)methyl]-C-methylcarbonimidoyl]amino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C25H23BrFN3O2
|
1
|
| 1 |
EC50 = 227 nM
|
|
|
|
CP0371787
|
5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine; oxalic acid
Show/Hide
|
C14H23N3OS
|
2
|
| 1 |
EC50 = 229 nM
|
|
|
| 2 |
Ki = 11.22 nM
|
|
|
|
CP0546188
|
11,13-dimethyl-6-pyrrolidin-1-yl-8-thia-5,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
Show/Hide
|
C16H17N3S
|
1
|
| 1 |
EC50 = 233 nM
|
|
|
|
CP0554116
|
[4-(11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl)piperidin-1-yl]-(1-methylcyclopropyl)methanone
Show/Hide
|
C21H24N4OS
|
1
|
| 1 |
EC50 = 234 nM
|
|
|
|
CP0413709
|
N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-4-methylbenzamide
Show/Hide
|
C27H28FN3O2
|
1
|
| 1 |
EC50 = 235 nM
|
|
|
|
CP0540738
|
N-cyclopentyl-4-[[(8,9-dimethylpyrazolo[3,4-h]quinazolin-4-yl)amino]methyl]benzamide
Show/Hide
|
C24H26N6O
|
1
|
| 1 |
EC50 = 239 nM
|
|
|
|
CP0488022
|
5-amino-N-(6,7-dihydro-5H-cyclopenta[b]pyridin-6-yl)-7-methyl-3-thia-1,10-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H17N5OS
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0533444
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamide
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C18H17Cl2N5O
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1
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| 1 |
EC50 = 243 nM
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CP0416484
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4-amino-N-[1-(5-chloro-3-fluoropyridin-2-yl)azetidin-3-yl]-2,3-dimethylindazole-5-carboxamide
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C18H18ClFN6O
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1
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| 1 |
EC50 = 244 nM
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CP0521380
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5-amino-N-[1-[5-chloro-2-(trifluoromethyl)pyridin-4-yl]azetidin-3-yl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
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C20H17ClF3N7OS
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1
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| 1 |
EC50 = 250 nM
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CP0316264
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6-fluoro-5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
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C18H24FN3O2
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2
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| 1 |
EC50 = 251.19 nM
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| 2 |
EC50 = 501.19 nM
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CP0521382
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3-amino-4-methyl-7-oxo-N-[[4-(trifluoromethylsulfonyl)phenyl]methyl]-6H-thieno[2,3-c]pyridine-2-carboxamide
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C17H14F3N3O4S2
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1
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| 1 |
EC50 = 260 nM
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CP0384237
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5-amino-N-(2,3-dihydro-1H-inden-2-yl)-7-methyl-3-thia-1,10-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
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C20H18N4OS
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1
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| 1 |
EC50 = 270 nM
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CP0573004
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5-amino-7,11-dimethyl-N-[1-[5-(trifluoromethyl)pyrimidin-2-yl]azetidin-3-yl]-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
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C19H17F3N8OS
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1
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| 1 |
EC50 = 270 nM
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CP0164191
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-8,9-dimethylpyrazolo[3,4-h]quinazolin-4-amine
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C19H17Cl2N7
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1
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| 1 |
EC50 = 275 nM
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CP0495331
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11,13-dimethyl-6-pyrrolidin-1-yl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
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C15H16N4S
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1
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| 1 |
EC50 = 277 nM
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CP0554115
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11,13-dimethyl-N-[(4-methylsulfonylphenyl)methyl]-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
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C19H18N4O2S2
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1
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| 1 |
EC50 = 293 nM
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CP0552533
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[3-amino-8-(pyridin-4-ylmethoxy)-5-thia-7-azatricyclo[7.3.0.02,6]dodeca-1(9),2(6),3,7-tetraen-4-yl]-pyridin-4-ylmethanone
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C22H18N4O2S
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1
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| 1 |
EC50 = 295 nM
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CP0488020
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5-amino-N-(6,7-dihydro-5H-cyclopenta[b]pyridin-6-yl)-7,11-dimethyl-3-thia-1,10-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
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C20H19N5OS
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1
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| 1 |
EC50 = 300 nM
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CP0368686
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-2,3-dimethylindazole-5-carboxamide
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C18H17Cl2N5O
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1
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| 1 |
EC50 = 308 nM
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CP0544486
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5-amino-N-[(4-methoxyphenyl)methyl]-7-methyl-3-thia-1,10-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
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C19H18N4O2S
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1
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| 1 |
EC50 = 310 nM
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CP0577297
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2-[4-[[(11,13-dimethyl-8-thia-5,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl)amino]methyl]phenyl]propan-2-ol
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C22H23N3OS
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1
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| 1 |
EC50 = 327 nM
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CP0580023
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11,13-dimethyl-N-(3-pyridin-4-ylcyclobutyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
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C20H19N5S
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1
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| 1 |
EC50 = 341 nM
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CP0384745
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4-bromo-N-[(1R,2R)-6-[[N-[(3-fluorophenyl)methyl]-C-methylcarbonimidoyl]amino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
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C25H23BrFN3O2
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1
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| 1 |
EC50 = 355 nM
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CP0549344
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N-cyclobutyl-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
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C15H16N4S
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1
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| 1 |
EC50 = 359 nM
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CP0125602
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4-amino-N-[1-(5-chloro-3-fluoropyridin-2-yl)azetidin-3-yl]-3-methylbenzotriazole-5-carboxamide
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C16H15ClFN7O
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1
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| 1 |
EC50 = 364 nM
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CP0365576
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-2,3-dimethylpyrazolo[3,4-c]pyridine-5-carboxamide
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C17H16Cl2N6O
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1
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| 1 |
EC50 = 370 nM
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CP0368567
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4-amino-N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-3-methylbenzotriazole-5-carboxamide
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C17H18ClN7O2
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1
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| 1 |
EC50 = 373 nM
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CP0570007
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-1,3-dimethylpyrazolo[3,4-c]pyridine-5-carboxamide
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C17H16Cl2N6O
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1
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| 1 |
EC50 = 375 nM
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CP0552939
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N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-8,9-dimethylpyrazolo[3,4-h]quinazolin-4-amine
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C20H20ClN7O
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1
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| 1 |
EC50 = 379 nM
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CP0384742
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4-fluoro-N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
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C26H25F2N3O2
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1
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| 1 |
EC50 = 392 nM
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CP0403240
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N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-4-(trifluoromethyl)benzamide
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C27H25F4N3O2
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1
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| 1 |
EC50 = 393 nM
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CP0384746
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4-chloro-N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
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C26H25ClFN3O2
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1
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| 1 |
EC50 = 405 nM
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CP0539560
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5-amino-N-[1-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)azetidin-3-yl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
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C19H20N8O2S
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1
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| 1 |
EC50 = 410 nM
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CP0487649
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-2,3-dimethylindazole-6-carboxamide
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C18H17Cl2N5O
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1
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| 1 |
EC50 = 420 nM
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CP0525626
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N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide
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C18H19ClN6O2
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1
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| 1 |
EC50 = 430 nM
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CP0495330
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6-(3-azabicyclo[3.1.0]hexan-3-yl)-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
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C16H16N4S
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1
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| 1 |
EC50 = 453 nM
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CP0125583
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N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-2,3-dimethylpyrazolo[3,4-c]pyridine-5-carboxamide
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C18H19ClN6O2
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1
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| 1 |
EC50 = 454 nM
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CP0575171
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6-(3,3-difluoroazetidin-1-yl)-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
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C14H12F2N4S
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1
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| 1 |
EC50 = 456 nM
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CP0437935
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4-amino-N-[1-(3-chloro-5-cyanopyridin-2-yl)azetidin-3-yl]-3-methylbenzotriazole-5-carboxamide
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C17H15ClN8O
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1
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| 1 |
EC50 = 462 nM
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CP0437938
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4-(2,2-dimethylpropyl)-8,9-dimethylpyrazolo[3,4-h]quinazoline
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C16H20N4
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1
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| 1 |
EC50 = 467 nM
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CP0511552
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-3-methyl-2-(trifluoromethyl)benzimidazole-5-carboxamide
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C18H14Cl2F3N5O
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1
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| 1 |
EC50 = 468 nM
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CP0365621
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N-[(3-fluoro-4-methoxyphenyl)methyl]-8,9-dimethylpyrazolo[3,4-h]quinazolin-4-amine
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C19H18FN5O
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1
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| 1 |
EC50 = 470 nM
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CP0125600
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N-cyclobutyl-4-[[(8,9-dimethylpyrazolo[3,4-h]quinazolin-4-yl)amino]methyl]benzamide
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C23H24N6O
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1
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| 1 |
EC50 = 475 nM
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CP0548599
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-2-methyl-1,3-benzothiazole-5-carboxamide
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C17H14Cl2N4OS
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1
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| 1 |
EC50 = 494 nM
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CP0180462
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3-amino-4,6-dimethyl-N-p-anisyl-thieno[2,3-b]pyridine-2-carboxamide
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C18H19N3O2S
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1
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| 1 |
EC50 = 495 nM
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CP0388124
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3-[1-(4-methoxy-1-methylcyclohexyl)piperidin-4-yl]-5-methyl-1,3-benzoxazol-2-one
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C21H30N2O3
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1
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| 1 |
EC50 = 501.19 nM
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CP0514870
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CHEMBL1223939
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C23H34N2O5S
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1
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| 1 |
EC50 = 501.19 nM
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CP0521199
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6-(8,9-dimethylpyrazolo[3,4-h]quinazolin-4-yl)-2-oxa-6-azaspiro[3.3]heptane
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C16H17N5O
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1
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| 1 |
EC50 = 528 nM
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CP0554733
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2-[4-[[(8,9-dimethylpyrazolo[3,4-h]quinazolin-4-yl)amino]methyl]phenyl]propan-2-ol
Show/Hide
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C21H23N5O
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1
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| 1 |
EC50 = 552 nM
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CP0540745
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-3-ethyl-2-methylindazole-5-carboxamide
Show/Hide
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C19H19Cl2N5O
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1
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| 1 |
EC50 = 584 nM
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CP0416478
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N-[(3-fluoro-4-methoxyphenyl)methyl]-1-methyltriazolo[4,5-h]quinazolin-6-amine
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C17H15FN6O
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1
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| 1 |
EC50 = 592 nM
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CP0416477
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4-amino-N-[1-(3,4-difluorophenyl)azetidin-3-yl]-2,3-dimethylindazole-5-carboxamide
Show/Hide
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C19H19F2N5O
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1
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| 1 |
EC50 = 619 nM
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CP0477347
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5-amino-N-[1-(5-tert-butyl-1,3,4-oxadiazol-2-yl)azetidin-3-yl]-7,11-dimethyl-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
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C20H24N8O2S
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1
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| 1 |
EC50 = 620 nM
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CP0549820
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cyclopropyl-[4-(11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl)piperidin-1-yl]methanone
Show/Hide
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C20H22N4OS
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1
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| 1 |
EC50 = 620 nM
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CP0540737
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8,9-dimethyl-4-pyrrolidin-1-ylpyrazolo[3,4-h]quinazoline
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C15H17N5
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1
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| 1 |
EC50 = 624 nM
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CP0186462
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5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
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C18H25N3O2
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1
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| 1 |
EC50 = 630.96 nM
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CP0540743
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-2,3-dimethylbenzimidazole-5-carboxamide
Show/Hide
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C18H17Cl2N5O
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1
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| 1 |
EC50 = 654 nM
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CP0416481
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-3-methylbenzotriazole-5-carboxamide
Show/Hide
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C16H14Cl2N6O
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1
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| 1 |
EC50 = 675 nM
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CP0416594
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-6-fluoro-2,3-dimethylindazole-5-carboxamide
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C18H16Cl2FN5O
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1
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| 1 |
EC50 = 739 nM
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CP0533443
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-1,3-dimethylindazole-5-carboxamide
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C18H17Cl2N5O
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1
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| 1 |
EC50 = 746 nM
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CP0544323
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6-[3-(methoxymethyl)azetidin-1-yl]-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
Show/Hide
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C16H18N4OS
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1
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| 1 |
EC50 = 762 nM
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CP0374543
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3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-2-oxo-1,3-benzoxazole-5-carbonitrile
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C22H29N3O3
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1
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| 1 |
EC50 = 794.33 nM
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CP0374547
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3-[1-[4-(2-methoxyethoxy)-1-methylcyclohexyl]piperidin-4-yl]-2-oxo-1,3-benzoxazole-5-carbonitrile
Show/Hide
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C23H31N3O4
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1
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| 1 |
EC50 = 794.33 nM
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CP0437936
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4-amino-3-methyl-N-[1-[2-(trifluoromethyl)pyridin-4-yl]azetidin-3-yl]benzotriazole-5-carboxamide
Show/Hide
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C17H16F3N7O
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1
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| 1 |
EC50 = 814 nM
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CP0558184
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N-cyclopentyl-1-methyltriazolo[4,5-h]quinazolin-6-amine
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C14H16N6
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1
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| 1 |
EC50 = 820 nM
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CP0384743
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Talsaclidine
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C10H15NO
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1
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| 1 |
EC50 = 844 nM
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CP0416483
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N-cyclopentyl-8,9-dimethylpyrazolo[3,4-h]quinazolin-4-amine
Show/Hide
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C16H19N5
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1
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| 1 |
EC50 = 848 nM
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CP0416459
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N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-2,3-dimethylimidazo[1,2-a]pyrimidine-6-carboxamide
Show/Hide
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C17H16Cl2N6O
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1
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| 1 |
EC50 = 849 nM
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CP0548619
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2-[4-[dideuterio-[(8,9-dimethylpyrazolo[3,4-h]quinazolin-4-yl)amino]methyl]phenyl]propan-2-ol
Show/Hide
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C21H23N5O
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1
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| 1 |
EC50 = 886 nM
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CP0528084
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2-[4-[[(11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl)amino]methyl]phenyl]propan-2-ol
Show/Hide
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C21H22N4OS
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1
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| 1 |
EC50 = 910 nM
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CP0416392
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N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-3-methyl-2-(trifluoromethyl)benzimidazole-5-carboxamide
Show/Hide
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C19H17ClF3N5O2
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1
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| 1 |
EC50 = 940 nM
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CP0487657
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N-(2,2-dimethylpropyl)-4-[[(8,9-dimethylpyrazolo[3,4-h]quinazolin-4-yl)amino]methyl]benzamide
Show/Hide
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C24H28N6O
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1
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| 1 |
EC50 = 957 nM
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CP0532792
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5-amino-7-methyl-N-[[4-(trifluoromethylsulfonyl)phenyl]methyl]-3-thia-1,10,11-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
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C18H14F3N5O3S2
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1
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| 1 |
EC50 = 990 nM
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CP0416746
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N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-4-phenylbenzamide
Show/Hide
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C32H30FN3O2
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1
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| 1 |
EC50 = 1060 nM
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CP0513110
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4-bromo-N-[(1R,2R)-6-[[N-(4-fluorophenyl)-C-methylcarbonimidoyl]amino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
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C24H21BrFN3O2
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1
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| 1 |
EC50 = 1110 nM
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CP0577293
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11,13-dimethyl-N-[[4-(morpholin-4-ylmethyl)phenyl]methyl]-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
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C23H25N5OS
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1
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| 1 |
EC50 = 1110 nM
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CP0577298
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N-(1,3-dihydro-2-benzofuran-5-ylmethyl)-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
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C20H18N4OS
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1
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| 1 |
EC50 = 1140 nM
|
|
|
|
CP0549290
|
N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamide
Show/Hide
|
C19H20ClN5O2
|
1
|
| 1 |
EC50 = 1153 nM
|
|
|
|
CP0488019
|
5-amino-N-(2,3-dihydro-1H-inden-2-yl)-7,11-dimethyl-3-thia-1,10-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C21H20N4OS
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0422605
|
4-bromo-N-[(1R,2R)-2-hydroxy-6-[[N-[2-(4-methoxyphenyl)ethyl]-C-methylcarbonimidoyl]amino]-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C27H28BrN3O3
|
1
|
| 1 |
EC50 = 1360 nM
|
|
|
|
CP0548613
|
N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-2,3-dimethylbenzimidazole-5-carboxamide
Show/Hide
|
C19H20ClN5O2
|
1
|
| 1 |
EC50 = 1384 nM
|
|
|
|
CP0577294
|
11,13-dimethyl-N-[(2-methylpyrimidin-5-yl)methyl]-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C17H16N6S
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0527899
|
N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-1,3-dimethylpyrazolo[3,4-c]pyridine-5-carboxamide
Show/Hide
|
C18H19ClN6O2
|
1
|
| 1 |
EC50 = 1422 nM
|
|
|
|
CP0487659
|
4-amino-N-[1-(6-chloropyridin-2-yl)azetidin-3-yl]-2,3-dimethylindazole-5-carboxamide
Show/Hide
|
C18H19ClN6O
|
1
|
| 1 |
EC50 = 1454 nM
|
|
|
|
CP0389031
|
N-[(3,4-difluorophenyl)methyl]-8,9-dimethylpyrazolo[3,4-h]quinazolin-4-amine
Show/Hide
|
C18H15F2N5
|
1
|
| 1 |
EC50 = 1484 nM
|
|
|
|
CP0554118
|
N-[1-(2,5-dichloro-4- pyridyl)azetidin-3-yl]- 7,9-dimethyl- pyrido[3',2':4,5]furo[3,2- d]pyrimidin-4-amine dihydrochloride
Show/Hide
|
C19H16Cl2N6O
|
1
|
| 1 |
EC50 = 1490 nM
|
|
|
|
CP0548618
|
N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-1-methyltriazolo[4,5-h]quinazolin-6-amine
Show/Hide
|
C18H17ClN8O
|
1
|
| 1 |
EC50 = 1493 nM
|
|
|
|
CP0528141
|
N-[(6-imidazol-1-ylpyridin-3-yl)methyl]-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C20H17N7S
|
1
|
| 1 |
EC50 = 1560 nM
|
|
|
|
CP0374545
|
3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-5-methylsulfonyl-1,3-benzoxazol-2-one
Show/Hide
|
C22H32N2O5S
|
1
|
| 1 |
EC50 = 1584.89 nM
|
|
|
|
CP0374546
|
CHEMBL1223938
Show/Hide
|
C23H34N2O5S
|
1
|
| 1 |
EC50 = 1584.89 nM
|
|
|
|
CP0528086
|
N-Cyclobutyl-7,9-dimethyl-pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-4-amine
Show/Hide
|
C15H16N4O
|
1
|
| 1 |
EC50 = 1590 nM
|
|
|
|
CP0495329
|
N-[2-(4-methoxyphenyl)cyclopropyl]-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C21H20N4OS
|
1
|
| 1 |
EC50 = 1640 nM
|
|
|
|
CP0545956
|
2-[4-[[(1-methyltriazolo[4,5-h]quinazolin-6-yl)amino]methyl]phenyl]propan-2-ol
Show/Hide
|
C19H20N6O
|
1
|
| 1 |
EC50 = 1719 nM
|
|
|
|
CP0416479
|
4-amino-N-[1-(5-cyanopyridin-2-yl)azetidin-3-yl]-3-methylbenzotriazole-5-carboxamide
Show/Hide
|
C17H16N8O
|
1
|
| 1 |
EC50 = 1723 nM
|
|
|
|
CP0416391
|
N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-2,3-dimethylimidazo[1,2-a]pyrimidine-6-carboxamide
Show/Hide
|
C18H19ClN6O2
|
1
|
| 1 |
EC50 = 1832 nM
|
|
|
|
CP0384243
|
5-amino-7,11-dimethyl-N-[[4-(trifluoromethylsulfonyl)phenyl]methyl]-3-thia-1,10,12-triazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C19H16F3N5O3S2
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0537030
|
5-amino-N-[(1S)-2,3-dihydro-1H-inden-1-yl]-7,11-dimethyl-3-thia-1,10-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C21H20N4OS
|
1
|
| 1 |
EC50 = 2000 nM
|
|
|
|
CP0528103
|
5-amino-N-[(1S)-2,3-dihydro-1H-inden-1-yl]-7-methyl-3-thia-1,10-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene-4-carboxamide
Show/Hide
|
C20H18N4OS
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0577300
|
2-[4-[[(11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl)amino]methyl]-3-fluorophenyl]propan-2-ol
Show/Hide
|
C21H21FN4OS
|
1
|
| 1 |
EC50 = 2320 nM
|
|
|
|
CP0416480
|
4-amino-N-[1-(3,4-difluorophenyl)azetidin-3-yl]-3-methylbenzotriazole-5-carboxamide
Show/Hide
|
C17H16F2N6O
|
1
|
| 1 |
EC50 = 2427 nM
|
|
|
|
CP0416389
|
N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-6,7-difluoro-2,3-dimethylindazole-5-carboxamide
Show/Hide
|
C18H15Cl2F2N5O
|
1
|
| 1 |
EC50 = 2540 nM
|
|
|
|
CP0576669
|
N-(6,7-dihydro-5H-cyclopenta[b]pyridin-2-ylmethyl)-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C20H19N5S
|
1
|
| 1 |
EC50 = 2560 nM
|
|
|
|
CP0554119
|
N-cyclopropyl-7,9-dimethyl- pyrido[3',2':4,5]furo[3,2- d]pyrimidin-4-amine hydrochloride
Show/Hide
|
C14H14N4O
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
|
CP0495321
|
6,11,13-trimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaene
Show/Hide
|
C12H11N3S
|
1
|
| 1 |
EC50 = 2820 nM
|
|
|
|
CP0554117
|
11,13-dimethyl-6-(1,3-thiazol-2-yl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
Show/Hide
|
C14H10N4S2
|
1
|
| 1 |
EC50 = 3410 nM
|
|
|
|
CP0416485
|
4-amino-N-[1-(3-fluoropyridin-2-yl)azetidin-3-yl]-2,3-dimethylindazole-5-carboxamide
Show/Hide
|
C18H19FN6O
|
1
|
| 1 |
EC50 = 3547 nM
|
|
|
|
CP0521201
|
4-amino-N-[1-(3-chloro-5-fluoropyridin-2-yl)azetidin-3-yl]-3-methylbenzotriazole-5-carboxamide
Show/Hide
|
C16H15ClFN7O
|
1
|
| 1 |
EC50 = 3602 nM
|
|
|
|
CP0429187
|
4-bromo-N-[(1R,2R)-6-[1-[(4-fluorophenyl)methyl-methylamino]ethylideneamino]-2-hydroxy-2,3-dihydro-1H-inden-1-yl]benzamide
Show/Hide
|
C26H25BrFN3O2
|
1
|
| 1 |
EC50 = 3720 nM
|
|
|
|
CP0487646
|
N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-2,3-dimethylindazole-6-carboxamide
Show/Hide
|
C19H20ClN5O2
|
1
|
| 1 |
EC50 = 3882 nM
|
|
|
|
CP0546189
|
6-cyclopropyl-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
Show/Hide
|
C14H13N3S
|
1
|
| 1 |
EC50 = 3900 nM
|
|
|
|
CP0573322
|
N-[[4-(difluoromethoxy)phenyl]methyl]-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C19H16F2N4OS
|
1
|
| 1 |
EC50 = 4010 nM
|
|
|
|
CP0437937
|
4-amino-N-[1-(6-chloropyridin-2-yl)azetidin-3-yl]-3-methylbenzotriazole-5-carboxamide
Show/Hide
|
C16H16ClN7O
|
1
|
| 1 |
EC50 = 4499 nM
|
|
|
|
CP0542816
|
11,13-dimethyl-6-piperidin-4-yl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
Show/Hide
|
C16H18N4S
|
1
|
| 1 |
EC50 = 6110 nM
|
|
|
|
CP0487658
|
4-amino-N-[1-(5-fluoropyrimidin-2-yl)azetidin-3-yl]-2,3-dimethylindazole-5-carboxamide
Show/Hide
|
C17H18FN7O
|
1
|
| 1 |
EC50 = 6214 nM
|
|
|
|
CP0551262
|
11,13-dimethyl-N-[1-[5-(trifluoromethyl)pyrimidin-2-yl]azetidin-3-yl]-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C19H16F3N7S
|
1
|
| 1 |
EC50 = 6550 nM
|
|
|
|
CP0542815
|
6-cyclohexyl-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
Show/Hide
|
C17H19N3S
|
1
|
| 1 |
EC50 = 6790 nM
|
|
|
|
CP0551263
|
2-[4-[(11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl)oxymethyl]phenyl]propan-2-ol
Show/Hide
|
C21H21N3O2S
|
1
|
| 1 |
EC50 = 8740 nM
|
|
|
|
CP0400206
|
2-(4-chloro-1,3-thiazol-2-yl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C16H18ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0405616
|
2-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-6-[[4-(1,3-oxazol-4-yl)phenyl]methyl]-3H-isoindol-1-one
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0468871
|
(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-pyridin-4-ylmethanol
Show/Hide
|
C14H14N4OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0475302
|
(3-amino-5-chloro-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-phenylmethanol
Show/Hide
|
C16H15ClN2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0482498
|
[3-amino-8-(2-morpholin-4-ylethoxy)-5-thia-7-azatricyclo[7.3.0.02,6]dodeca-1(9),2(6),3,7-tetraen-4-yl]-pyridin-4-ylmethanol
Show/Hide
|
C22H26N4O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0482499
|
(3-amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(2,4-difluorophenyl)methanol
Show/Hide
|
C16H14F2N2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0483188
|
(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-pyridin-3-ylmethanol
Show/Hide
|
C14H14N4OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0538509
|
[3-amino-8-(pyridin-4-ylmethoxy)-5-thia-7-azatricyclo[7.3.0.02,6]dodeca-1(9),2(6),3,7-tetraen-4-yl]-pyridin-4-ylmethanol
Show/Hide
|
C22H20N4O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0540692
|
(3-amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-phenylmethanol
Show/Hide
|
C16H16N2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0544632
|
(3-amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(3-chloro-4-fluorophenyl)methanol
Show/Hide
|
C16H14ClFN2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0544633
|
(3-amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-pyridin-4-ylmethanol
Show/Hide
|
C15H15N3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0549269
|
1-amino-2-[hydroxy(pyridin-4-yl)methyl]-6,7,8,9-tetrahydro-4H-thieno[2,3-c]isoquinolin-5-one
Show/Hide
|
C17H17N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0552531
|
(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(4-methoxyphenyl)methanol
Show/Hide
|
C16H17N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0552532
|
(3-amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-(4-methoxyphenyl)methanol
Show/Hide
|
C17H18N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0566451
|
(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-(2,4-difluorophenyl)methanol
Show/Hide
|
C15H13F2N3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0566452
|
(3-amino-5-chloro-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-pyridin-3-ylmethanol
Show/Hide
|
C15H14ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0566453
|
4-[(3-amino-4,6-dimethylthieno[2,3-b]pyridin-2-yl)-hydroxymethyl]phenol
Show/Hide
|
C16H16N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0574785
|
(5-amino-3,4-dimethylthieno[2,3-c]pyridazin-6-yl)-phenylmethanol
Show/Hide
|
C15H15N3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0389029
|
N-[1-(2,5-dichloropyridin-4-yl)azetidin-3-yl]-3-methyl-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide
Show/Hide
|
C16H14Cl2N6O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0416390
|
N-[1-(5-chloro-2-methoxypyridin-4-yl)azetidin-3-yl]-3-methyl-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide
Show/Hide
|
C17H17ClN6O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Ki = 12.59 nM
|
|
|
|
CP0128076
|
8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]diazepine
Show/Hide
|
C17H17ClN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0189250
|
3-chloro-8-fluoro-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C19H17ClFN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0315086
|
3-chloro-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C19H18ClN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0450960
|
8-fluoro-3-methyl-6-(1,2,3,6-tetrahydropyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C19H18FN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0450964
|
8-ethyl-3-methyl-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C22H25N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0533787
|
8-fluoro-3-methyl-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C20H20FN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0533788
|
3-chloro-6-(1-ethyl-3,6-dihydro-2H-pyridin-4-yl)-8-fluoro-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C20H19ClFN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0533789
|
8-chloro-3-fluoro-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C19H17ClFN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0551894
|
3-chloro-8-fluoro-6-(1,2,3,6-tetrahydropyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C18H15ClFN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0551895
|
3,8-dimethyl-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C21H23N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0551896
|
8-methoxy-3-methyl-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0570014
|
3-chloro-8-fluoro-6-(1-propan-2-yl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C21H21ClFN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0549343
|
N-[(5-fluoropyrimidin-2-yl)methyl]-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C16H13FN6S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0423460
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-pentylurea
Show/Hide
|
C14H26N6OS
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.052 nM
|
|
|
|
CP0543296
|
1-[(1R)-1-phenylethyl]-3-[N'-[3-(1H-1,2,4-triazol-5-yl)propyl]carbamimidoyl]urea;dihydrochloride
Show/Hide
|
C15H23Cl2N7O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.052 nM
|
|
|
|
CP0551746
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-pentylurea;2,2,2-trifluoroacetic acid
Show/Hide
|
C16H25F6N7O5S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.052 nM
|
|
|
|
CP0085573
|
3-[1-[3-(4-fluorophenoxy)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
|
C21H24FN3O2
|
1
|
| 1 |
EC50 > 25118.86 nM
|
|
|
|
CP0113928
|
1-(4-bromobenzyl)indoline-2,3-dione
Show/Hide
|
C15H10BrNO2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0168609
|
ethyl 4-[(3R)-3-[(2-methylbenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
Show/Hide
|
C21H31N3O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0392295
|
4-[2-(o-toluoylamino)ethylamino]piperidine-1-carboxylic acid ethyl ester;hydrochloride
Show/Hide
|
C18H27N3O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0305211
|
1-(1'-(2-methylbenzyl)-1,4'-bipiperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C25H32N4O
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0240069
|
N-ethyl-1-(1H-indazol-5-ylsulfonyl)-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
Show/Hide
|
C23H25F3N4O3S
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0413445
|
N-benzyl-1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-N-ethylpiperidine-4-carboxamide
Show/Hide
|
C23H28N2O5S
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0412637
|
1-methyl-4-[[6-(1-methylpyrazol-4-yl)pyridin-3-yl]methyl]-N-(oxan-4-yl)pyrrolo[2,3-b]pyridine-6-carboxamide
Show/Hide
|
C24H26N6O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0635477
|
(2-Carbamoyloxy-ethyl)-trimethyl-ammonium chloride
Show/Hide
|
C6H15ClN2O2
|
5
|
| 1 |
EC50 = 60000 nM
|
|
|
| 2 |
IC50 = 0.4 nM
|
|
|
| 3 |
Ki = 24 nM
|
|
|
| 4 |
Ki = 2600 nM
|
|
|
| 5 |
Ki = 6309.57 nM
|
|
|
|
CP0577296
|
N-[(3-fluoro-4-methoxyphenyl)methyl]-11,13-dimethyl-8-thia-5,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-6-amine
Show/Hide
|
C20H18FN3OS
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0543300
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-benzylurea;2,2,2-trifluoroacetic acid
Show/Hide
|
C18H21F6N7O5S
|
2
|
| 1 |
EC50 > 3162.28 nM
|
|
|
| 2 |
Kd = 0.052 nM
|
|
|
|
CP0673968
|
SID50106181
Show/Hide
|
C21H26INO2
|
2
|
| 1 |
IC50 = 0.49 nM
|
|
|
| 2 |
Ki = 0.88 nM
|
|
|
|
CP0527617
|
CHEMBL4851711
Show/Hide
|
C23H29FN4O
|
1
|
| 1 |
IC50 = 1.738 nM
|
|
|
|
CP0040500
|
3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9-aza-tricyclo[3.3.1.0*2,4*]non-7-yl ester
Show/Hide
|
C18H24NO4+
|
2
|
| 1 |
IC50 = 2.3 nM
|
|
|
| 2 |
Ki = 0.1413 nM
|
|
|
|
CP0857826
|
1-Cyclohexyl-1-phenyl-3-piperidin-1-yl-propan-1-ol hydrochloride
Show/Hide
|
C20H32ClNO
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0577073
|
6-(2-chloro-5-fluorophenyl)-N-[[6-(cyclohexylmethyl)-6-azaspiro[2.5]octan-2-yl]methyl]pyridazin-3-amine
Show/Hide
|
C25H32ClFN4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0854268
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid cyclohexyl ester oxalic acid
Show/Hide
|
C22H29NO6
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0847169
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid phenethyl ester oxalic acid
Show/Hide
|
C24H27NO6
|
1
|
| 1 |
IC50 = 69.7 nM
|
|
|
|
CP0389547
|
[1-[6-(2,4-difluorophenoxy)pyrimidin-4-yl]piperidin-4-yl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
Show/Hide
|
C25H24F2N4O2
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
Ki = 10.3 nM
|
|
|
|
CP0849760
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid cyclohexyl ester oxalic acid
Show/Hide
|
C22H29NO6
|
1
|
| 1 |
IC50 = 108.7 nM
|
|
|
|
CP0054849
|
(3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methyl-6-(S)-methyl-piperidin-2-yl)-vinyl]-decahydro-naphtho[2,3-c]furan-1-one
Show/Hide
|
C22H35NO2
|
2
|
| 1 |
IC50 = 114.4 nM
|
|
|
| 2 |
Ki = 10.96 nM
|
|
|
|
CP0869657
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2-cyclohexyl-ethyl ester oxalic acid
Show/Hide
|
C24H33NO6
|
1
|
| 1 |
IC50 = 134.7 nM
|
|
|
|
CP0847735
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2-p-tolyl-ethyl ester oxalic acid
Show/Hide
|
C25H29NO6
|
1
|
| 1 |
IC50 = 138 nM
|
|
|
|
CP0845078
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid cyclohexylmethyl ester oxalic acid
Show/Hide
|
C23H31NO6
|
1
|
| 1 |
IC50 = 142.7 nM
|
|
|
|
CP0861085
|
1-Ethyl-4-phenyl-piperidine-3-carboxylic acid phenethyl ester oxalic acid
Show/Hide
|
C24H29NO6
|
1
|
| 1 |
IC50 = 145.4 nM
|
|
|
|
CP0870135
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid benzyl ester hydrochloride
Show/Hide
|
C21H24ClNO2
|
1
|
| 1 |
IC50 = 146.3 nM
|
|
|
|
CP0405990
|
2-(3-chlorophenyl)-6-fluoro-N-[[(3R,4S)-3-methylpiperidin-4-yl]methyl]benzamide
Show/Hide
|
C20H22ClFN2O
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0860558
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid cyclohexylmethyl ester oxalic acid
Show/Hide
|
C23H31NO6
|
1
|
| 1 |
IC50 = 167.6 nM
|
|
|
|
CP0056034
|
11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
IC50 = 246.8 nM
|
|
|
|
CP0850038
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid octyl ester oxalic acid
Show/Hide
|
C24H35NO6
|
1
|
| 1 |
IC50 = 258.8 nM
|
|
|
|
CP0404712
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid nonyl ester
Show/Hide
|
C23H35NO2
|
1
|
| 1 |
IC50 = 282.3 nM
|
|
|
|
CP0458944
|
8,9-Dimethoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C24H26N2O5
|
1
|
| 1 |
IC50 = 301.1 nM
|
|
|
|
CP0448414
|
9-Methoxy-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C22H22N2O4
|
1
|
| 1 |
IC50 = 333.5 nM
|
|
|
|
CP0383656
|
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid propyl ester
Show/Hide
|
C24H26N2O4
|
1
|
| 1 |
IC50 = 359.6 nM
|
|
|
|
CP0878826
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid hexyl ester oxalic acid
Show/Hide
|
C22H31NO6
|
1
|
| 1 |
IC50 = 367 nM
|
|
|
|
CP0473116
|
2-(3-chloro-4-methylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0860587
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid pentyl ester oxalic acid
Show/Hide
|
C21H29NO6
|
1
|
| 1 |
IC50 = 432.4 nM
|
|
|
|
CP0451231
|
2,9-Dimethyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 464.8 nM
|
|
|
|
CP0854470
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid benzyl ester hydrochloride
Show/Hide
|
C21H24ClNO2
|
1
|
| 1 |
IC50 = 472.8 nM
|
|
|
|
CP0408846
|
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid methyl ester
Show/Hide
|
C22H22N2O4
|
1
|
| 1 |
IC50 = 501 nM
|
|
|
|
CP0869546
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid butyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 524 nM
|
|
|
|
CP0392493
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid decyl ester
Show/Hide
|
C24H37NO2
|
1
|
| 1 |
IC50 = 566.2 nM
|
|
|
|
CP0878820
|
(3R,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid hexyl ester oxalic acid
Show/Hide
|
C22H33NO6
|
1
|
| 1 |
IC50 = 572.7 nM
|
|
|
|
CP0886216
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid heptyl ester oxalic acid
Show/Hide
|
C23H33NO6
|
1
|
| 1 |
IC50 = 617.1 nM
|
|
|
|
CP0849749
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid butyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 656.3 nM
|
|
|
|
CP0854465
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid pentyl ester oxalic acid
Show/Hide
|
C21H29NO6
|
1
|
| 1 |
IC50 = 701 nM
|
|
|
|
CP0847343
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid isobutyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 742.6 nM
|
|
|
|
CP0859753
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2-cyclohexyl-ethyl ester oxalic acid
Show/Hide
|
C24H33NO6
|
1
|
| 1 |
IC50 = 836.1 nM
|
|
|
|
CP0863347
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid isobutyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 896.9 nM
|
|
|
|
CP0845389
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 5-phenyl-pentyl ester oxalic acid
Show/Hide
|
C27H33NO6
|
1
|
| 1 |
IC50 = 951.2 nM
|
|
|
|
CP0914385
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 3-phenyl-propyl ester hydrochloride
Show/Hide
|
C23H28ClNO2
|
1
|
| 1 |
IC50 = 1132.1 nM
|
|
|
|
CP0853934
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 3-phenyl-propyl ester hydrochloride
Show/Hide
|
C23H28ClNO2
|
1
|
| 1 |
IC50 = 1160.8 nM
|
|
|
|
CP0863310
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 3-cyclohexyl-propyl ester oxalic acid
Show/Hide
|
C25H35NO6
|
1
|
| 1 |
IC50 = 1167.2 nM
|
|
|
|
CP0376534
|
1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine; oxalic acid
Show/Hide
|
C9H13N3S2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0914612
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid octyl ester oxalic acid
Show/Hide
|
C24H35NO6
|
1
|
| 1 |
IC50 = 1250 nM
|
|
|
|
CP0558880
|
1-(1,3-benzodioxol-5-ylsulfonyl)-4-[4-[(2S)-2-methylpiperidin-1-yl]phenyl]piperazine
Show/Hide
|
C23H29N3O4S
|
1
|
| 1 |
IC50 = 1330 nM
|
|
|
|
CP0520019
|
1-(1,3-benzodioxol-5-ylsulfonyl)-4-[5-[(2S)-2-methylpiperidin-1-yl]pyridin-2-yl]piperazine
Show/Hide
|
C22H28N4O4S
|
1
|
| 1 |
IC50 = 1350 nM
|
|
|
|
CP0889381
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid propyl ester oxalic acid
Show/Hide
|
C19H25NO6
|
1
|
| 1 |
IC50 = 1409.3 nM
|
|
|
|
CP0500468
|
2,7-Dimethyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 1474.8 nM
|
|
|
|
CP0404049
|
8,9-Dimethoxy-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C23H24N2O5
|
1
|
| 1 |
IC50 = 1498.3 nM
|
|
|
|
CP0381434
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid nonyl ester
Show/Hide
|
C23H35NO2
|
1
|
| 1 |
IC50 = 1577.9 nM
|
|
|
|
CP0406059
|
2-(5-chloro-2-fluorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C19H20ClFN2O
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0448197
|
9-Ethoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C24H26N2O4
|
1
|
| 1 |
IC50 = 1624 nM
|
|
|
|
CP0914469
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid phenethyl ester oxalic acid
Show/Hide
|
C24H27NO6
|
1
|
| 1 |
IC50 = 1740.6 nM
|
|
|
|
CP0860615
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2-p-tolyl-ethyl ester oxalic acid
Show/Hide
|
C25H29NO6
|
1
|
| 1 |
IC50 = 1756.1 nM
|
|
|
|
CP0861075
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid hexyl ester oxalic acid
Show/Hide
|
C22H31NO6
|
1
|
| 1 |
IC50 = 2030 nM
|
|
|
|
CP0404668
|
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid isopropyl ester
Show/Hide
|
C24H26N2O4
|
1
|
| 1 |
IC50 = 2050 nM
|
|
|
|
CP0392206
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid decyl ester
Show/Hide
|
C24H37NO2
|
1
|
| 1 |
IC50 = 2123.9 nM
|
|
|
|
CP0850036
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid heptyl ester oxalic acid
Show/Hide
|
C23H33NO6
|
1
|
| 1 |
IC50 = 2196.7 nM
|
|
|
|
CP0861083
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2-(4-methoxy-phenyl)-ethyl ester oxalic acid
Show/Hide
|
C25H29NO7
|
1
|
| 1 |
IC50 = 2224.5 nM
|
|
|
|
CP0847170
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 5-phenyl-pentyl ester oxalic acid
Show/Hide
|
C27H33NO6
|
1
|
| 1 |
IC50 = 2388.2 nM
|
|
|
|
CP0453286
|
2-Methyl-9-phenoxy-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C28H26N2O4
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1
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| 1 |
IC50 = 2633.7 nM
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CP0849717
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 4-phenyl-butyl ester oxalic acid
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C26H31NO6
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1
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| 1 |
IC50 = 2775.5 nM
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CP0400212
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2-(3-chlorophenyl)-6-fluoro-N-[[(3S,4R)-4-fluoro-3-methylpiperidin-4-yl]methyl]benzamide
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C20H21ClF2N2O
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1
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| 1 |
IC50 = 3162.28 nM
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CP0416360
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2-(3-chlorophenyl)-N-[(3-methylpiperidin-4-yl)methyl]benzamide
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C20H23ClN2O
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1
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| 1 |
IC50 = 3162.28 nM
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CP0859752
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester oxalic acid
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C18H23NO6
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1
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| 1 |
IC50 = 3226.4 nM
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CP0510618
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2-Methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C22H22N2O3
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1
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| 1 |
IC50 = 3713.8 nM
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CP0910088
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid propyl ester oxalic acid
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C19H25NO6
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1
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| 1 |
IC50 = 3788.8 nM
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CP0886217
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2,2-diphenyl-ethyl ester oxalic acid
Show/Hide
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C30H31NO6
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1
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| 1 |
IC50 = 4162.1 nM
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CP0393182
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(3R,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid cyclohexyl ester
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C20H29NO2
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1
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| 1 |
IC50 = 4246.3 nM
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CP0448346
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8,9-Dimethoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene
Show/Hide
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C21H22N2O3
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1
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| 1 |
IC50 = 4741.3 nM
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CP0037621
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(oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one
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C12H18N2O
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3
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| 1 |
IC50 = 5000 nM
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| 2 |
Ki = 1.5 nM
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| 3 |
Ki = 160 nM
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CP0386486
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2-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
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C19H21ClN2O
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1
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| 1 |
IC50 = 5011.87 nM
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CP0454447
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8-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C23H24N2O4
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1
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| 1 |
IC50 = 6027.8 nM
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CP0853885
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 4-phenyl-butyl ester oxalic acid
Show/Hide
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C26H31NO6
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1
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| 1 |
IC50 = 7422 nM
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CP0854016
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2,2-diphenyl-ethyl ester oxalic acid
Show/Hide
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C30H31NO6
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1
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| 1 |
IC50 = 7708.4 nM
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CP0860591
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(3S,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid cyclohexyl ester oxalic acid
Show/Hide
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C22H31NO6
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1
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| 1 |
IC50 = 7900 nM
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CP0400210
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2-(3-chlorophenyl)-6-fluoro-N-(1,2,3,6-tetrahydropyridin-4-ylmethyl)benzamide
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C19H18ClFN2O
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1
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| 1 |
IC50 = 7943.28 nM
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CP0880188
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(3R,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid phenethyl ester oxalic acid
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C24H29NO6
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1
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| 1 |
IC50 = 8122.8 nM
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CP0862779
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1-Ethyl-5-(3-pentyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-1,2,3,6-tetrahydro-pyridine oxalic acid
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C22H29N3O5
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1
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| 1 |
IC50 = 8392.3 nM
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CP0846965
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid phenyl ester oxalic acid
Show/Hide
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C22H23NO6
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1
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| 1 |
IC50 = 8428.6 nM
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CP0403792
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9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene
Show/Hide
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C20H20N2O2
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1
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| 1 |
IC50 = 9735.2 nM
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CP0448496
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2-Methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid methyl ester
Show/Hide
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C21H20N2O3
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1
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| 1 |
IC50 = 9927.5 nM
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CP0482548
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2-[4-(1,3-benzodioxol-5-ylsulfonyl)piperazin-1-yl]-5-[(2S)-2-methylpiperidin-1-yl]pyrazine
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C21H27N5O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0559065
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1-(1,3-benzodioxol-5-ylsulfonyl)-4-[6-[(2S)-2-methylpiperidin-1-yl]pyridin-3-yl]piperazine
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C22H28N4O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0577135
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N-[6-(2-chloro-5-fluorophenyl)pyridazin-3-yl]-6-(oxan-4-ylmethyl)-6-azaspiro[2.5]octan-2-amine
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C23H28ClFN4O
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1
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| 1 |
IC50 > 10000 nM
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CP0447292
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(9bS)-9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
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C24H17ClF2N2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0576561
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(3R,4S)-1-(2,3-dihydro-1-benzofuran-5-ylsulfonyl)-3-fluoro-4-[(1-methylimidazol-2-yl)sulfanylmethyl]piperidine
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C18H22FN3O3S2
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1
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| 1 |
IC50 > 10000 nM
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CP0850116
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester oxalic acid
Show/Hide
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C18H23NO6
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1
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| 1 |
IC50 = 10383 nM
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CP0847050
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid methyl ester oxalic acid
Show/Hide
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C17H21NO6
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1
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| 1 |
IC50 = 13042.1 nM
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CP0860435
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid methyl ester oxalic acid
Show/Hide
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C17H21NO6
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1
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| 1 |
IC50 = 13691.8 nM
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CP0457513
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8-Methyl-6,7,8,9-tetrahydro-5H-2,4-dithia-1,3,8-triaza-cyclopenta[a]naphthalene
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C9H11N3S2
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1
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| 1 |
IC50 = 14500 nM
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CP0880203
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 3-cyclohexyl-propyl ester oxalic acid
Show/Hide
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C25H35NO6
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1
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| 1 |
IC50 = 19581.2 nM
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CP0287892
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2-(2-bromophenoxy)-1-(2,4-dihydroxyphenyl)ethanone
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C14H11BrO4
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1
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| 1 |
IC50 > 30000 nM
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CP0393505
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N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]quinoline-5-sulfonamide
Show/Hide
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C21H23N5O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0317131
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(9bS)-9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
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C23H15ClF2N2O2
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1
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| 1 |
IC50 > 30000 nM
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CP0381562
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9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
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C23H15ClF2N2O2
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1
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| 1 |
IC50 > 30000 nM
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CP0381587
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1-(3,4-difluorobenzoyl)-9b-phenyl-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
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C23H16F2N2O2
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1
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| 1 |
IC50 > 30000 nM
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CP0381598
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1-(4-fluorobenzoyl)-9b-phenyl-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
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C23H17FN2O2
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1
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| 1 |
IC50 > 30000 nM
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CP0550227
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5-[(3-acetylphenoxy)methyl]-N-methyl-N-[(1S)-1-pyridin-2-ylethyl]-1,2-oxazole-3-carboxamide
Show/Hide
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C21H21N3O4
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1
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| 1 |
IC50 > 30000 nM
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CP0854472
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid phenyl ester oxalic acid
Show/Hide
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C22H23NO6
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1
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| 1 |
IC50 = 31125.4 nM
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CP0861084
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2-(4-methoxy-phenyl)-ethyl ester oxalic acid
Show/Hide
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C25H29NO7
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1
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| 1 |
IC50 = 42312.8 nM
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CP0018455
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1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid methyl ester;hydrobromide
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C8H13NO2
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3
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| 1 |
IC50 = 47500 nM
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| 2 |
Ki = 26 nM
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| 3 |
Ki = 2400 nM
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CP0855705
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1-Ethyl-3-(3-pentyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-1,2,3,6-tetrahydro-pyridine oxalic acid
Show/Hide
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C22H29N3O5
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1
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| 1 |
IC50 = 63337.5 nM
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CP0382980
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6,7,8,9-Tetrahydro-2-thia-1,3,8-triaza-cyclopenta[a]naphthalene
Show/Hide
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C9H9N3S
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1
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| 1 |
IC50 = 100000 nM
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CP0421075
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1,4-Dimethyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine
Show/Hide
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C10H15N3S2
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1
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| 1 |
IC50 > 100000 nM
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CP0199765
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5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide
Show/Hide
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C28H32N2O3
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1
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| 1 |
Ki = 0.115 nM
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CP0109931
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ATROPEN
Show/Hide
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C17H23NO3
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3
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| 1 |
Ki = 0.34 nM
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| 2 |
Ki = 0.64 nM
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| 3 |
Ki = 1.6 nM
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CP0070586
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Ipratropium Bromide
Show/Hide
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C20H30BrNO3
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1
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| 1 |
Ki = 0.382 nM
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CP0869209
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(S)-2-((S)-2,2-diphenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H26INOS
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1
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| 1 |
Ki = 0.4677 nM
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CP0881062
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(R)-2-((2R,5R)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H32INOS
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1
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| 1 |
Ki = 0.7079 nM
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CP0399528
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1,9-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl)-1,2,5-thiadiazol-3-yloxy]nonane
Show/Hide
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C25H38N6O2S2
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1
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| 1 |
Ki = 0.7762 nM
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CP0877788
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(S)-2-((2S,5S)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H32INOS
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1
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| 1 |
Ki = 0.871 nM
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CP0889526
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(S)-2-((2R,5S)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H32INOS
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1
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| 1 |
Ki = 0.871 nM
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CP0378654
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1-[3-[4-[7-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]heptyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C32H47N5O2S
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1
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| 1 |
Ki = 0.8913 nM
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CP0067390
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ethyl 6-butyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C26H30N2O4
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1
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| 1 |
Ki = 1 nM
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CP0459891
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ethyl 17-methylsulfanyl-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C25H28N2O3S
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1
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| 1 |
Ki = 1 nM
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CP0858802
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(2R,2'S,5'R)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
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C20H29NOS
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1
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| 1 |
Ki = 1 nM
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CP0378646
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1-[3-[4-[9-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]nonyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C34H51N5O2S
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1
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| 1 |
Ki = 1.072 nM
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CP0877786
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(2S,2'S,5'S)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
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C20H29NOS
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1
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| 1 |
Ki = 1.202 nM
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CP0881063
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(2R,2'R,5'R)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
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C20H29NOS
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1
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| 1 |
Ki = 1.259 nM
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CP0858907
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(S)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
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C20H26INO2
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1
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| 1 |
Ki = 1.479 nM
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CP0881061
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(R)-2-((2S,5R)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H32INOS
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1
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| 1 |
Ki = 1.82 nM
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CP0393079
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ethyl 17-methoxy-7-methyl-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C26H30N2O4
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1
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| 1 |
Ki = 1.995 nM
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CP0404800
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ethyl 17-methoxy-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C25H28N2O4
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1
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| 1 |
Ki = 1.995 nM
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CP0425298
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ethyl 7-methyl-17-methylsulfanyl-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C26H30N2O3S
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1
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| 1 |
Ki = 1.995 nM
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CP0877787
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(2R,5'R)-1-methyl2-(2,2-diphenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
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C20H23NOS
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1
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| 1 |
Ki = 1.995 nM
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CP0440619
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1-azabicyclo[2.2.2]octan-3-yl N-[2-(4-fluorophenyl)ethyl]-N-phenylcarbamate
Show/Hide
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C22H25FN2O2
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1
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| 1 |
Ki = 2.2 nM
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CP0849054
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1-[1-(3,3,3-Triphenyl-propionyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carboxylic acid (1-cyclohexylmethyl-piperidin-3-ylmethyl)-amide
Show/Hide
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C44H56N4O3
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1
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| 1 |
Ki = 2.3 nM
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CP0858803
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(2S,2'R,5'S)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
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C20H29NOS
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1
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| 1 |
Ki = 2.344 nM
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CP0879684
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(S)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N-dimethylmethanamine Oxalate
Show/Hide
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C21H25NO6
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1
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| 1 |
Ki = 2.344 nM
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CP0867620
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(+/-)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
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C20H26INO2
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1
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| 1 |
Ki = 2.63 nM
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CP0392351
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ethyl 6-butyl-17-methylsulfanyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C26H30N2O3S
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1
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| 1 |
Ki = 3.02 nM
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CP0492196
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ethyl 6-ethyl-17-methoxy-7-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C25H28N2O4
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1
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| 1 |
Ki = 3.02 nM
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CP0876058
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(2S,5'S)-1-methyl 2-(2,2-diphenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
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C20H23NOS
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1
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| 1 |
Ki = 3.311 nM
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CP0869207
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(R)-2-((R)-2,2-diphenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
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C21H26INOS
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1
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| 1 |
Ki = 3.467 nM
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CP0062485
|
4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
Show/Hide
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C22H31NO3
|
1
|
| 1 |
Ki = 3.631 nM
|
|
|
|
CP0480403
|
ethyl 6-ethyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C24H26N2O4
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0439251
|
(R)-cyclohexyl-[5-[(2R)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
Show/Hide
|
C22H29NO2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0020189
|
6-acetoxy-8-azonia-bicyclo[3.2.1]octane
Show/Hide
|
C9H15NO2
|
2
|
| 1 |
Ki = 4 nM
|
|
|
| 2 |
Ki = 33 nM
|
|
|
|
CP0894757
|
(R)-2-(5-((R)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H32INO2
|
1
|
| 1 |
Ki = 4.266 nM
|
|
|
|
CP0858902
|
(+/-)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N-dimethylmethanamine Oxalate
Show/Hide
|
C21H25NO6
|
1
|
| 1 |
Ki = 4.898 nM
|
|
|
|
CP0871074
|
(2R,5R)-2-cyclohexyl-2-phenyl-5-((dimethylamino)methyl)-1,3-oxathiolane methiodide
Show/Hide
|
C19H30INOS
|
1
|
| 1 |
Ki = 6.166 nM
|
|
|
|
CP0058613
|
CAS_132947
Show/Hide
|
C64H77N13O6
|
1
|
| 1 |
Ki = 6.457 nM
|
|
|
|
CP0415932
|
1-[3-[4-[11-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]undecyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C36H55N5O2S
|
1
|
| 1 |
Ki = 6.607 nM
|
|
|
|
CP0407747
|
ethyl 6-methyl-17-methylsulfanyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C23H24N2O3S
|
1
|
| 1 |
Ki = 7.079 nM
|
|
|
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CP0456704
|
4-[4-[6-(3,3-dimethylpiperidin-1-yl)pyridazin-3-yl]piperazin-1-yl]sulfonyl-3,5-dimethyl-1,2-oxazole
Show/Hide
|
C20H30N6O3S
|
1
|
| 1 |
Ki = 7.78 nM
|
|
|
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CP0378653
|
1-[3-[4-[5-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]pentyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C30H43N5O2S
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0225899
|
AQ-RA 741
Show/Hide
|
C27H37N5O2
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
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CP0010653
|
2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrrolidin-3-yl}-2,2-diphenyl-acetamide (Darifenacin)
Show/Hide
|
C28H30N2O2
|
1
|
| 1 |
Ki = 8.6 nM
|
|
|
|
CP0217520
|
AF-DX 384
Show/Hide
|
C27H38N6O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0474634
|
ethyl 17-methoxy-6-pentyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C27H32N2O4
|
1
|
| 1 |
Ki = 10.96 nM
|
|
|
|
CP0849742
|
1-(3,3,3-Triphenyl-propionyl)-pyrrolidine-2-carboxylic acid {2-[(1-cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-ethyl}-amide
Show/Hide
|
C42H54N4O3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0467303
|
(2R)-N-(1-cyclopentylmethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C43H51F3N4O4
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0045063
|
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Show/Hide
|
C17H20N4S
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0847176
|
N-({2-[(1-Cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-ethylcarbamoyl}-methyl)-3,3,3-triphenyl-propionamide
Show/Hide
|
C39H50N4O3
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0409139
|
ethyl 6-hexyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C28H34N2O4
|
1
|
| 1 |
Ki = 14.13 nM
|
|
|
|
CP0405687
|
cyclohexyl-[5-(1-methylpyrrolidin-2-yl)furan-2-yl]-phenylmethanol
Show/Hide
|
C22H29NO2
|
1
|
| 1 |
Ki = 14.13 nM
|
|
|
|
CP0406146
|
1-[3-[4-[13-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]tridecyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C38H59N5O2S
|
1
|
| 1 |
Ki = 14.45 nM
|
|
|
|
CP0376946
|
prop-2-enyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
Ki = 15.14 nM
|
|
|
|
CP0377061
|
ethyl 17-methoxy-6,7-dimethyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C24H26N2O4
|
1
|
| 1 |
Ki = 15.14 nM
|
|
|
|
CP0874916
|
2-(5-(cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H32INO2
|
1
|
| 1 |
Ki = 15.49 nM
|
|
|
|
CP0858486
|
2-(5-(cyclohexyl(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H32INO
|
1
|
| 1 |
Ki = 19.5 nM
|
|
|
|
CP0394158
|
(2R)-N-(1-cyclopropylmethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1 -[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C41H47F3N4O4
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0054630
|
((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-trimethyl-ammonium
Show/Hide
|
C9H20NO2+
|
3
|
| 1 |
Ki = 23 nM
|
|
|
| 2 |
Ki = 1400 nM
|
|
|
| 3 |
Ki = 28000 nM
|
|
|
|
CP0390496
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H43Cl3N4O4
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0413084
|
1-azabicyclo[2.2.2]octan-3-yl N-[2-(4-methoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0399526
|
1-[3-[4-[3-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]propyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C28H39N5O2S
|
1
|
| 1 |
Ki = 26.3 nM
|
|
|
|
CP0458127
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H43F3N4O4
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0859758
|
6-(3,3,3-Triphenyl-propionylamino)-hexanoic acid (1-cyclohexylmethyl-piperidin-3-ylmethyl)-amide
Show/Hide
|
C40H53N3O2
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0886180
|
N-(2-{2-[(1-Cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-ethylcarbamoyl}-ethyl)-3,3,3-triphenyl-propionamide
Show/Hide
|
C40H52N4O3
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0390495
|
(2R)-N-(1-cyclobutylmethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C42H49F3N4O4
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0413481
|
1-[3-[4-[9-[1-[3-(2-oxo-3,4-dihydroquinolin-1-yl)propyl]piperidin-4-yl]nonyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C43H64N4O2
|
1
|
| 1 |
Ki = 32.36 nM
|
|
|
|
CP0880938
|
(S)-2-(5-((R)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H32INO2
|
1
|
| 1 |
Ki = 33.11 nM
|
|
|
|
CP0858619
|
2-(5-benzhydrylfuran-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H26INO
|
1
|
| 1 |
Ki = 38.02 nM
|
|
|
|
CP0376654
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-[(3R)-3-piperidinylmethyl]-pyrrolidine-2-carboxamide
Show/Hide
|
C37H41F3N4O4
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0408072
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine -2-yl)-carbonyl-N-(1-methyl-4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H43F3N4O4
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0374663
|
(8-methyl-8-azabicyclo[3.2.1]octan-6-yl) 2,2,2-trichloroethyl carbonate
Show/Hide
|
C11H16Cl3NO3
|
2
|
| 1 |
Ki = 42 nM
|
|
|
| 2 |
Ki = 2300 nM
|
|
|
|
CP0067391
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H41F3N4O4
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0860436
|
1-(3,3,3-Triphenyl-propionyl)-pyrrolidine-2-carboxylic acid {[(1-cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-methyl}-amide
Show/Hide
|
C41H52N4O3
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0409449
|
4-Nitro-benzoic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester
Show/Hide
|
C14H16N2O4
|
2
|
| 1 |
Ki = 48 nM
|
|
|
| 2 |
Ki = 450 nM
|
|
|
|
CP0393859
|
(2R)-N-(1-cyclopentyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)-propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C42H49F3N4O4
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0543664
|
N-ethyl-2,2-dimethyl-N-[3-[1-[2-oxo-2-(6-oxo-5H-benzo[b][1,4]benzodiazepin-11-yl)ethyl]piperidin-4-yl]propyl]pentanamide
Show/Hide
|
C32H44N4O3
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0376043
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H41Cl3N4O4
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0398877
|
(R)-cyclohexyl-[5-[(2S)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
Show/Hide
|
C22H29NO2
|
1
|
| 1 |
Ki = 54.95 nM
|
|
|
|
CP0377612
|
N-[3-[[1-(cyclohexylmethyl)piperidin-3-yl]methylamino]-3-oxopropyl]-4-(3,3,3-triphenylpropanoylamino)butanamide
Show/Hide
|
C41H54N4O3
|
1
|
| 1 |
Ki = 60 nM
|
|
|
|
CP0402148
|
17-methoxy-6-methyl-5-(3-methyl-1,2,4-oxadiazol-5-yl)-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene
Show/Hide
|
C23H22N4O3
|
1
|
| 1 |
Ki = 61.66 nM
|
|
|
|
CP0917620
|
2-(5-(hydroxydiphenylmethyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H26INO2
|
1
|
| 1 |
Ki = 64.57 nM
|
|
|
|
CP0382995
|
butyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C25H28N2O4
|
1
|
| 1 |
Ki = 67.61 nM
|
|
|
|
CP0875623
|
(R)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N-dimethylmethanamine Oxalate
Show/Hide
|
C21H25NO6
|
1
|
| 1 |
Ki = 70.79 nM
|
|
|
|
CP0392367
|
prop-2-enyl 17-methoxy-7-[(4-methoxyphenyl)methyl]-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C32H32N2O5
|
1
|
| 1 |
Ki = 72.44 nM
|
|
|
|
CP0392482
|
benzyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C28H26N2O4
|
1
|
| 1 |
Ki = 72.44 nM
|
|
|
|
CP0404810
|
N-[[1-(cyclohexylmethyl)piperidin-3-yl]methyl]-4-[[2-(3,3,3-triphenylpropanoylamino)acetyl]amino]butanamide
Show/Hide
|
C40H52N4O3
|
1
|
| 1 |
Ki = 74 nM
|
|
|
|
CP0388205
|
2-[5-[cyclohexyl(phenyl)methyl]furan-2-yl]-1-methylpyrrolidine
Show/Hide
|
C22H29NO
|
1
|
| 1 |
Ki = 77.62 nM
|
|
|
|
CP0377860
|
8-azabicyclo[3.2.1]octan-6-yl propanoate
Show/Hide
|
C10H17NO2
|
2
|
| 1 |
Ki = 85 nM
|
|
|
| 2 |
Ki = 660 nM
|
|
|
|
CP0390498
|
(2R)-N-(1-ethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C39H45F3N4O4
|
1
|
| 1 |
Ki = 92 nM
|
|
|
|
CP0413482
|
1-[3-[4-(13-hydroxytridecyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C30H50N2O2
|
1
|
| 1 |
Ki = 95.5 nM
|
|
|
|
CP0378256
|
ethyl 7-benzyl-6-ethyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C31H32N2O4
|
1
|
| 1 |
Ki = 97.72 nM
|
|
|
|
CP0431004
|
[5-(1-methylpyrrolidin-2-yl)furan-2-yl]-diphenylmethanol
Show/Hide
|
C22H23NO2
|
1
|
| 1 |
Ki = 104.71 nM
|
|
|
|
CP0409101
|
ethyl 7-ethyl-17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C25H28N2O4
|
1
|
| 1 |
Ki = 109.65 nM
|
|
|
|
CP0378643
|
1-[3-[4-(11-hydroxyundecyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C28H46N2O2
|
1
|
| 1 |
Ki = 112.2 nM
|
|
|
|
CP0431973
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-((3R)-3-piperidinylmethyl)-pyrrolidine-2-carboxamide
Show/Hide
|
C37H41Cl3N4O4
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0040250
|
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
Show/Hide
|
C21H25N3O2S
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0390497
|
(2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-yl]carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H46N4O4
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0858903
|
(R)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
|
C20H26INO2
|
1
|
| 1 |
Ki = 151.36 nM
|
|
|
|
CP0378645
|
1-[3-[4-(9-hydroxynonyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C26H42N2O2
|
1
|
| 1 |
Ki = 154.88 nM
|
|
|
|
CP0033479
|
(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Show/Hide
|
C17H19ClN2S
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0439204
|
2-(5-benzhydrylfuran-2-yl)-1-methylpyrrolidine
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C22H23NO
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1
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| 1 |
Ki = 158.49 nM
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CP0502455
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(3S,3aS,4R,4aS,8aS,9aR)-4-[(E)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 173.78 nM
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CP0485213
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(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-[1-(2-propyl)-4-piperidinylmethyl]pyrrolidine-2-carboxamide
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C34H36F3N3O4
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1
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| 1 |
Ki = 180 nM
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CP0374791
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Benzoic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester
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C14H17NO2
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2
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| 1 |
Ki = 190 nM
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| 2 |
Ki = 500 nM
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CP0415357
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methyl 17-methoxy-6,7-dimethyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
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C23H24N2O4
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1
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| 1 |
Ki = 190.55 nM
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CP0393635
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1-[3-[4-(2-phenylethyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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C25H32N2O
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1
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| 1 |
Ki = 199.53 nM
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CP0232092
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1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C21H32N2O
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1
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| 1 |
Ki = 208.93 nM
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CP0459833
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2-(4-(pyrrolidin-1-yl)but-2-ynyl)isoxazolidin-3-one
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C11H16N2O2
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1
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| 1 |
Ki = 222 nM
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CP0393862
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(2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-yl]carbonyl-N-((3R)-3-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
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C37H44N4O4
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1
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| 1 |
Ki = 290 nM
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CP0440485
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(8-methyl-8-azabicyclo[3.2.1]octan-6-yl) cyclohexanecarboxylate
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C15H25NO2
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2
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| 1 |
Ki = 300 nM
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| 2 |
Ki = 700 nM
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CP0404711
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ethyl 17-chloro-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
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C22H21ClN2O3
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1
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| 1 |
Ki = 363.08 nM
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CP0859818
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(R)-2-(5-((S)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
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C23H32INO2
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1
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| 1 |
Ki = 371.54 nM
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CP0393625
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1-[3-[4-(7-hydroxyheptyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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C24H38N2O2
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1
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| 1 |
Ki = 389.05 nM
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CP0514143
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CAS_91533
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C20H24N2
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1
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| 1 |
Ki = 407.38 nM
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CP0404340
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Benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-6-yl ester
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C15H19NO2
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2
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| 1 |
Ki = 410 nM
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| 2 |
Ki = 910 nM
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CP0378647
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1-[3-[4-(5-hydroxypentyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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C22H34N2O2
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1
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| 1 |
Ki = 446.68 nM
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CP0390494
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(2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-yl]carbonyl-N-(4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
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C37H44N4O4
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1
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| 1 |
Ki = 480 nM
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CP0388200
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(S)-cyclohexyl-[5-[(2R)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
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C22H29NO2
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1
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| 1 |
Ki = 549.54 nM
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CP0411640
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1-[3-(4-pentylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C22H34N2O
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1
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| 1 |
Ki = 575.44 nM
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CP0379138
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1-[3-[4-(3-hydroxypropyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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C20H30N2O2
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1
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| 1 |
Ki = 588.84 nM
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CP0003459
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3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
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C28H37N5OS
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1
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| 1 |
Ki = 590 nM
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CP0403577
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(3S,3aR,4S,4aR,8aR,9aS)-4-[(E)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 616.6 nM
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CP0900137
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N,N-dimethyl-4-[(5-methylisoxazol-3-yl)oxy]but-2-yn-1-amine methiodide
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C11H17IN2O2
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1
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| 1 |
Ki = 682 nM
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CP0116478
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1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C24H30N2O
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1
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| 1 |
Ki = 724.44 nM
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CP0880166
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2-(4-Piperidin-1-ylbut-2-yn-1-yl)isoxazolidin-3-one oxalate
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C14H20N2O6
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1
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| 1 |
Ki = 792 nM
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CP0379402
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(3S,3aR,4S,4aR,8aR,9aS)-4-[(Z)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 794.33 nM
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CP0383280
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8-azabicyclo[3.2.1]octan-6-yl cyclohexanecarboxylate
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C14H23NO2
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2
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| 1 |
Ki = 840 nM
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| 2 |
Ki = 2200 nM
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CP0381042
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(3S,3aR,4R,4aS,8aR,9aS)-4-[(Z)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 891.25 nM
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CP0392743
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(3S,3aR,4R,4aS,8aR,9aS)-4-[2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethynyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H33NO2
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1
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| 1 |
Ki = 891.25 nM
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CP0024400
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6-acetoxy-8-methyl-8-azonia-bicyclo[3.2.1]octane
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C10H17NO2
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2
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| 1 |
Ki = 900 nM
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| 2 |
Ki = 8300 nM
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CP0377264
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(8-methyl-8-azabicyclo[3.2.1]octan-6-yl) propanoate
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C11H19NO2
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2
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| 1 |
Ki = 960 nM
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| 2 |
Ki = 1400 nM
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CP0139206
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Arecaidine Propargyl Ester
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C10H13NO2
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1
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| 1 |
Ki = 977.24 nM
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CP0480607
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(3S,3aS,4R,4aS,8aS,9aR)-4-[(Z)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 1000 nM
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CP0415400
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Cevimeline
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C10H17NOS
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1
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| 1 |
Ki = 1023.29 nM
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CP0897808
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N,N-dimethyl-4-[(5-methylisoxazol-3-yl)oxy]-but-2-yn-1-amine fumarate
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C14H18N2O6
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1
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| 1 |
Ki = 1095 nM
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CP0403333
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1-azabicyclo[2.2.2]octan-3-yl (3E)-3-(pyridin-3-ylmethylidene)indene-1-carboxylate
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C23H22N2O2
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1
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| 1 |
Ki = 1230.27 nM
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CP0489929
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1-[3-(4-phenylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C23H28N2O
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1
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| 1 |
Ki = 1288.25 nM
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CP0377555
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5-benzyl-17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene
Show/Hide
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C27H26N2O2
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1
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| 1 |
Ki = 1348.96 nM
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CP0167696
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2-acetoxypropyl(trimethyl)ammonium;chloride
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C8H18NO2+
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1
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| 1 |
Ki = 1600 nM
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CP0393633
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1-[3-(4-propylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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C20H30N2O
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1
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| 1 |
Ki = 1659.59 nM
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CP0880167
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1-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]piperidine methiodide
Show/Hide
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C13H21IN2O2
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1
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| 1 |
Ki = 1681 nM
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CP0378979
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1-azabicyclo[2.2.2]octan-3-yl (3E)-3-(pyridin-2-ylmethylidene)indene-1-carboxylate
Show/Hide
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C23H22N2O2
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1
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| 1 |
Ki = 1698.24 nM
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CP0408533
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(3S,3aR,4S,4aR,8aR,9aS)-4-[2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethynyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H33NO2
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1
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| 1 |
Ki = 1737.8 nM
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CP0883987
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(R)-2-((5-Chlorothiophen-2-yl)ethynyl)-N-(tetrahydrofuran-3-yl)-9H-purin-6-amine
Show/Hide
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C15H12ClN5OS
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1
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| 1 |
Ki = 1740 nM
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CP0467135
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1-azabicyclo[2.2.2]octan-3-yl (3E)-3-(pyridin-4-ylmethylidene)indene-1-carboxylate
Show/Hide
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C23H22N2O2
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1
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| 1 |
Ki = 1819.7 nM
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CP0418924
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(3S,3aS,4R,4aS,8aS,9aR)-4-[2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethynyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H33NO2
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1
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| 1 |
Ki = 1949.84 nM
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CP0377554
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ethyl 15-chloro-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C22H21ClN2O3
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1
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| 1 |
Ki = 1949.84 nM
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CP0858932
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2-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]-1,2,3,4-tetrahydroisoquinoline methiodide
Show/Hide
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C17H21IN2O2
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1
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| 1 |
Ki = 2265 nM
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CP0129619
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N-[3-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]-3-hydroxycyclobutyl]naphthalene-2-carboxamide
Show/Hide
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C27H34N4O2S
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1
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| 1 |
Ki = 2279 nM
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CP0860901
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(S)-2-(5-((S)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H32INO2
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1
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| 1 |
Ki = 2344.23 nM
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CP0472845
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1-[3-(4-benzylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C23H29N3O
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1
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| 1 |
Ki = 2630.27 nM
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CP0073146
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benzyl 7-(4-cyclopentylpiperazin-1-yl)-3,4-dihydro-1H-isoquinoline-2-carboxylate
Show/Hide
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C26H33N3O2
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1
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| 1 |
Ki = 2681 nM
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CP0443229
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(S)-cyclohexyl-[5-[(2S)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
Show/Hide
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C22H29NO2
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1
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| 1 |
Ki = 3090.3 nM
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CP0411642
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1-[3-(4-butylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C20H31N3O
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1
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| 1 |
Ki = 3162.28 nM
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CP0895034
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2-(5-Methyl-2-furyl)-1-methylpyrrolidine Methiodide
Show/Hide
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C11H18INO
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1
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| 1 |
Ki = 4365.16 nM
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CP0870440
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(S)-1,1-Dimethyl-2-(5-methyl-furan-2-yl)-pyrrolidinium
Show/Hide
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C11H18INO
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1
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| 1 |
Ki = 5128.61 nM
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CP0393626
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1-[3-[4-(2-phenylethyl)piperazin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C24H31N3O
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1
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| 1 |
Ki = 5128.61 nM
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CP0858931
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5-phenyl-3-[(4-pyrrolidin-1-ylbut-2-yn-1-yl)oxy]-isoxazole fumarate
Show/Hide
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C21H22N2O6
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1
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| 1 |
Ki = 5478 nM
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CP0873039
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5-methyl-3-[(4-pyrrolidin-1-ylbut-2-yn-1-yl)oxy]isoxazole methiodide
Show/Hide
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C13H19IN2O2
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1
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| 1 |
Ki = 5932 nM
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CP0858930
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5-phenyl-3-[(4-pyrrolidin-1-ylbut-2-yn-1-yl)oxy]isoxazole methiodide
Show/Hide
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C18H21IN2O2
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1
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| 1 |
Ki = 5986 nM
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CP0880168
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1-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]piperidine oxalate
Show/Hide
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C14H20N2O6
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1
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| 1 |
Ki = 6041 nM
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CP0249974
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5-methylfurmethide
Show/Hide
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C9H16NO+
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1
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| 1 |
Ki = 6309.57 nM
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CP0895036
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2-(2-Furyl)-1-methylpyrrolidineMethiodide
Show/Hide
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C10H16INO
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1
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| 1 |
Ki = 6456.54 nM
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CP0021606
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8-Aza-bicyclo[3.2.1]octane-6-carboxylic acid methyl ester
Show/Hide
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C9H15NO2
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1
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| 1 |
Ki = 7900 nM
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CP0848059
|
SID855871
Show/Hide
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C8H18INO2
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1
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| 1 |
Ki = 8912.51 nM
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CP0848084
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[4-(4-chloro-phenylcarbamoyloxy)-but-2-ynyl]-trimethyl-ammonium chloride
Show/Hide
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C14H18Cl2N2O2
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1
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| 1 |
Ki = 9120.11 nM
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CP0773921
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SID50106034
Show/Hide
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C14H18Cl2N2O2
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1
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| 1 |
Ki = 9120.11 nM
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CP0423369
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(McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2-ynyl]-trimethyl-ammonium; chloride
Show/Hide
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C14H18ClN2O2+
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1
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| 1 |
Ki = 9120.11 nM
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CP0232093
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1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C22H27N3O
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1
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| 1 |
Ki = 9332.54 nM
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CP0393627
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1-[3-(4-methylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C18H26N2O
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1
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| 1 |
Ki = 9332.54 nM
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CP0376953
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N-ethyl-17-methoxy-N,6-dimethyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxamide
Show/Hide
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C24H27N3O3
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1
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| 1 |
Ki = 9772.37 nM
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CP0845388
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Cis-N,N,N-trimethyl-1-((2R,6S)-6-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C9H20INO2
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2
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| 1 |
Ki = 9772.37 nM
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| 2 |
Ki = 11481.54 nM
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CP0876609
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1-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]indoline methiodide
Show/Hide
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C16H19IN2O2
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1
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| 1 |
Ki > 10000 nM
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CP0002070
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1-(1H-Indol-3-yl)-2-propanamine
Show/Hide
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C11H14N2
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1
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| 1 |
Ki > 10000 nM
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CP0002071
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N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-prop-2-enylprop-2-en-1-amine
Show/Hide
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C17H22N2O
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1
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| 1 |
Ki > 10000 nM
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CP0635067
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2-amino-6-chloro-3,4-dihydroquinazoline hydrochloride
Show/Hide
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C8H9Cl2N3
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1
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| 1 |
Ki > 10000 nM
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CP0054519
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(1R,12R,13S,17R,21S)-12-ethyl-18-propyl-7-(trifluoromethyl)-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene
Show/Hide
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C25H31F3N2
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1
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| 1 |
Ki > 10000 nM
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CP0085414
|
(3aS,6R,6aS,9aR,9bR)-6-benzyl-1-methyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one
Show/Hide
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C20H27NO
|
1
|
| 1 |
Ki > 10000 nM
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CP0387083
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(3aS,9bS)-3a-methyl-5-phenyl-2,3,4,9b-tetrahydro-1H-pyrrolo[2,3-c]quinoline
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C18H20N2
|
1
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| 1 |
Ki > 10000 nM
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CP0391120
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(1S,2R)-1-ethyl-7-methoxy-2-methyl-3,4-dihydro-1H-naphthalen-2-amine
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C14H21NO
|
1
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| 1 |
Ki > 10000 nM
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CP0391121
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(3S,4S)-4-ethyl-3,6-dimethyl-2,4-dihydrochromen-3-amine
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C13H19NO
|
1
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| 1 |
Ki > 10000 nM
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CP0391154
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(3aS,9bS)-7,9-dimethoxy-3a-methyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole
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C14H19NO3
|
1
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| 1 |
Ki > 10000 nM
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CP0411059
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(3S,4S)-4-ethyl-3-methyl-1-phenyl-2,4-dihydroquinolin-3-amine
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C18H22N2
|
1
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| 1 |
Ki > 10000 nM
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CP0878023
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Cis-((2R*,6S*)-6-Benzhydryl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
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C21H28INO2
|
1
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| 1 |
Ki = 11220.18 nM
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CP0409674
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N,N-dimethyl-2-[(3E)-3-(pyridin-2-ylmethylidene)inden-1-yl]ethanamine
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C19H20N2
|
1
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| 1 |
Ki = 12022.64 nM
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CP0393421
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2-(dimethylamino)ethyl (3E)-3-(pyridin-2-ylmethylidene)indene-1-carboxylate
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C20H20N2O2
|
1
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| 1 |
Ki = 12302.69 nM
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CP0431291
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ethyl 17-hydroxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C22H22N2O4
|
1
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| 1 |
Ki > 12302.69 nM
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CP0916821
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Cis-N,N,N-Trimethyl((2R*,6S*)-6-phenyl-1,4-dioxan-2-yl)methanaminium Iodide
Show/Hide
|
C14H22INO2
|
1
|
| 1 |
Ki = 12302.69 nM
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CP0410895
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2-(dimethylamino)ethyl (3E)-3-(pyridin-3-ylmethylidene)indene-1-carboxylate
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C20H20N2O2
|
1
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| 1 |
Ki = 12589.25 nM
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CP0845041
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(R)-1,1-Dimethyl-2-(5-methyl-furan-2-yl)-pyrrolidinium
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C11H18INO
|
1
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| 1 |
Ki = 13803.84 nM
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CP0379047
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2-(dimethylamino)ethyl (3E)-3-(pyridin-4-ylmethylidene)indene-1-carboxylate
Show/Hide
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C20H20N2O2
|
1
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| 1 |
Ki = 14791.08 nM
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CP0895136
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Trans-((2R*,6R*)-6-Benzhydryl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
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C21H28INO2
|
1
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| 1 |
Ki = 16982.44 nM
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CP0848060
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(R)-1-(1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium iodide
Show/Hide
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C8H18INO2
|
1
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| 1 |
Ki = 20892.96 nM
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CP0430112
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(3E)-N-[2-(dimethylamino)ethyl]-3-(pyridin-3-ylmethylidene)indene-1-carboxamide
Show/Hide
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C20H21N3O
|
1
|
| 1 |
Ki = 21379.62 nM
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CP0895035
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(S)-2-Furan-2-yl-1,1-dimethyl-pyrrolidinium
Show/Hide
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C10H16INO
|
1
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| 1 |
Ki = 21379.62 nM
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CP0449315
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N,N-dimethyl-2-[(3E)-3-(pyridin-3-ylmethylidene)inden-1-yl]ethanamine
Show/Hide
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C19H20N2
|
1
|
| 1 |
Ki = 22387.21 nM
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CP0393373
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(3E)-N-[2-(dimethylamino)ethyl]-3-(pyridin-4-ylmethylidene)indene-1-carboxamide
Show/Hide
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C20H21N3O
|
1
|
| 1 |
Ki = 24547.09 nM
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CP0898948
|
2-(5-Methyl-2-furyl)-1-methylpyrrolidine
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C10H15NO
|
1
|
| 1 |
Ki = 24547.09 nM
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CP0877929
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Cis-((2R*,6S*)-6-Ethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
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C10H22INO2
|
1
|
| 1 |
Ki = 25118.86 nM
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CP0859660
|
N,N,N-Trimethyl((2R*,5R*)-5,6,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C11H24INO2
|
1
|
| 1 |
Ki = 25703.96 nM
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CP0910892
|
(R)-2-Furan-2-yl-1,1-dimethyl-pyrrolidinium
Show/Hide
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C10H16INO
|
1
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| 1 |
Ki = 28183.83 nM
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CP0509683
|
(2R)-2-(5-methylfuran-2-yl)pyrrolidine
Show/Hide
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C9H13NO
|
1
|
| 1 |
Ki = 29512.09 nM
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CP0875624
|
Trans-N,N,N-Trimethyl((2R*,6R*)-6-phenyl-1,4-dioxan-2-yl)methanaminium Iodide
Show/Hide
|
C14H22INO2
|
1
|
| 1 |
Ki = 29512.09 nM
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CP0902206
|
N,N,N-Trimethyl((2R*,5S*)-5,6,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C11H24INO2
|
1
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| 1 |
Ki = 30199.52 nM
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CP0859714
|
((2R*,5S*,6S*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
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C10H22INO2
|
1
|
| 1 |
Ki = 30902.95 nM
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CP0429992
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(3E)-N-[2-(dimethylamino)ethyl]-3-(pyridin-2-ylmethylidene)indene-1-carboxamide
Show/Hide
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C20H21N3O
|
1
|
| 1 |
Ki = 33884.42 nM
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CP0859477
|
(6,6-Dimethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki = 44668.36 nM
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CP0474436
|
trimethyl-[[(2S,6S)-6-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide
Show/Hide
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C9H20NO2+
|
1
|
| 1 |
Ki = 45708.82 nM
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CP0374978
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(3E)-N-[2-(dimethylamino)ethyl]-N-methyl-3-(pyridin-2-ylmethylidene)indene-1-carboxamide
Show/Hide
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C21H23N3O
|
1
|
| 1 |
Ki = 46773.51 nM
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CP0455031
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(2R,3R,5R)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki = 46773.51 nM
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CP0433872
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(2S)-1-methyl-2-(5-methylfuran-2-yl)pyrrolidine
Show/Hide
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C10H15NO
|
1
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| 1 |
Ki = 47863.01 nM
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CP0876494
|
2-(5-Methyl-2-furyl)-pyrrolidine
Show/Hide
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C9H13NO
|
1
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| 1 |
Ki = 51286.14 nM
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CP0916016
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N,N,N-Trimethyl(5,5,6,6-tetramethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C12H26INO2
|
1
|
| 1 |
Ki = 53703.18 nM
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CP0405252
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(3E)-N-[2-(dimethylamino)ethyl]-N-methyl-3-(pyridin-3-ylmethylidene)indene-1-carboxamide
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
Ki = 54954.09 nM
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CP0500729
|
(2S)-2-(furan-2-yl)-1-methylpyrrolidine
Show/Hide
|
C9H13NO
|
1
|
| 1 |
Ki = 56234.13 nM
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CP0845387
|
N,N,N-Trimethyl((2R*,6S*)-5,5,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C11H24INO2
|
1
|
| 1 |
Ki = 57543.99 nM
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CP0372904
|
(2R)-1-methyl-2-(5-methylfuran-2-yl)pyrrolidine
Show/Hide
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C10H15NO
|
1
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| 1 |
Ki = 58884.37 nM
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CP0371717
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trimethyl-[[(2S,6R)-6-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide
Show/Hide
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C9H20NO2+
|
1
|
| 1 |
Ki = 69183.1 nM
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CP0910891
|
2-(2-Furyl)-1-methylpyrrolidine
Show/Hide
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C9H13NO
|
1
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| 1 |
Ki = 69183.1 nM
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CP0465871
|
(2R)-2-(furan-2-yl)-1-methylpyrrolidine
Show/Hide
|
C9H13NO
|
1
|
| 1 |
Ki = 79432.82 nM
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CP0859716
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()-(2R,6R)-N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C9H20INO2
|
2
|
| 1 |
Ki = 87096.36 nM
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| 2 |
Ki < 100000 nM
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CP0859717
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N,N,N-Trimethyl((2R*,6R*)-5,5,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C11H24INO2
|
1
|
| 1 |
Ki = 87096.36 nM
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CP0497956
|
2-(furan-2-yl)pyrrolidine
Show/Hide
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C8H11NO
|
1
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| 1 |
Ki = 87096.36 nM
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CP0377730
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(4-methylpiperazin-1-yl)-[(3E)-3-(pyridin-4-ylmethylidene)inden-1-yl]methanone
Show/Hide
|
C21H21N3O
|
1
|
| 1 |
Ki = 89125.09 nM
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CP0372804
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(2R)-2-(furan-2-yl)pyrrolidine
Show/Hide
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C8H11NO
|
1
|
| 1 |
Ki = 89125.09 nM
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CP0864337
|
N,N,N-trimethyl-1-((2R,5R)-5-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki = 93325.43 nM
|
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CP0859476
|
((2S*,5S*,6S*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki > 100000 nM
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CP0859713
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(2R*,5S*)-N,N,N-Trimethyl-(5-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki > 100000 nM
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CP0859715
|
((2R*,5R*,6S*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki > 100000 nM
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CP0868051
|
(5,5-Dimethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki > 100000 nM
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CP0904026
|
((2R*,5S*,6R*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki > 100000 nM
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CP0867621
|
Trans-((2R*,6R*)-6-Ethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0407014
|
(5S,2'S)-5-(1-methyl-2-pyrrolidinyl)oxazolidinone
Show/Hide
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C8H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0414425
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(5R,2'S)-5-(1-methyl-2-pyrrolidinyl)oxazolidinone
Show/Hide
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C8H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
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CP0846921
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(S)-N,N,N-trimethyl-1-(2-oxooxazolidin-5-yl)methanaminium
Show/Hide
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C7H15N2O2+
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0846922
|
(S)-2-(carbamoyloxymethyl)-1,1-dimethylpyrrolidinium
Show/Hide
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C8H17N2O2+
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0846927
|
(R)-5-((dimethylamino)methyl)oxazolidin-2-one
Show/Hide
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C6H12N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0848614
|
(S)-5-((dimethylamino)methyl)-3-methyloxazolidin-2-one
Show/Hide
|
C7H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0856191
|
(S)-(1-methylpyrrolidin-2-yl)methyl carbamate
Show/Hide
|
C7H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0860582
|
(R)-N,N,N-trimethyl-1-(3-methyl-2-oxooxazolidin-5-yl)methanaminium
Show/Hide
|
C8H17N2O2+
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0861363
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(S)-N,N,N-trimethyl-1-(3-methyl-2-oxooxazolidin-5-yl)methanaminium
Show/Hide
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C8H17N2O2+
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0866588
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(R)-N,N,N-trimethyl-1-(2-oxooxazolidin-5-yl)methanaminium
Show/Hide
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C7H15N2O2+
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0886638
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(R)-4-((S)-1-methylpyrrolidin-2-yl)oxazolidin-2-one
Show/Hide
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C8H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0902643
|
(R)-5-((dimethylamino)methyl)-3-methyloxazolidin-2-one
Show/Hide
|
C7H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
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CP0902877
|
(S)-5-((dimethylamino)methyl)oxazolidin-2-one
Show/Hide
|
C6H12N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
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CP0912137
|
(S)-4-((S)-1-methylpyrrolidin-2-yl)oxazolidin-2-one
Show/Hide
|
C8H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0848040
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(R)-N,N,N-Trimethyl-1-(2-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki > 100000 nM
|
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|
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CP0866923
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N,N,N-trimethyl-1-((2R,3S)-3-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
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CP0913147
|
N,N,N-trimethyl-1-((2R,3R)-3-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki > 100000 nM
|
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CP0425884
|
2-(3,4-dimethoxyphenyl)ethyl 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate
Show/Hide
|
C23H27NO4
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
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CP0307921
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
|
1
|
| 1 |
Ki > 1000 nM
|
|
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CP0467302
|
(R)-N-((S)-piperidin-3-ylmethyl)-1-((S)-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H44N4O3
|
1
|
| 1 |
Ki > 1700 nM
|
|
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CP0379516
|
(2S,3R,5S)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0379517
|
(2R,3S,5R)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0379521
|
(2R,3S,5R)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0379525
|
(2S,3R,5S)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
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CP0379526
|
(2R,3R,5R)-5-[(2R)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0379527
|
(2S,3S,5S)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0419569
|
(2R,3S,5R)-5-[(2R)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0419583
|
(2S,3R,5S)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
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CP0424750
|
(2R,3R,5R)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
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CP0431823
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(2R,3S,5R)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
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C9H17NO2S
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1
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| 1 |
Ki < 100000 nM
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CP0432602
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(2R,3R,5R)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
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C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
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|
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CP0449147
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(2S,3S,5S)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
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C9H17NO2S
|
1
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| 1 |
Ki < 100000 nM
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CP0461163
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(2S,3S,5S)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
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C10H20INO2S
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1
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| 1 |
Ki < 100000 nM
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