Brief Information of the Cell Line and Protein
Cell Line ID: CL000422 , OK
 Cell Line Info 
Synonyms
Opossum Kidney
OK-WT
Category Spontaneously immortalized cell line
Organism
Didelphis virginiana (North American opossum)
Cellosaurus ID
CVCL_0472
Protein ID: PT04309 , Sodium/hydrogen exchanger 3
 Protein Info 
Gene Name SLC9A3
Organism Rattus norvegicus, Rat
Protein Classification Transporter
Uniprot ID P26433
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000422
 Cell Line Info 
 Protein ID: PT04309
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0434864
 Compound Info 
US10272079, Compound 161
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C83H111Cl6N13O19S3
  1
1
IC50 = 0.631 nM
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CP0427000
 Compound Info 
US10272079, Compound 140
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C58H80F2N8O12S2
  1
1
IC50 = 1.259 nM
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CP0415046
 Compound Info 
US10272079, Compound 48
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C62H86N8O16S2
  2
1
IC50 = 1.413 nM
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2
IC50 = 28.18 nM
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CP0379929
 Compound Info 
US10272079, Compound 119
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C61H86N6O14S2
  1
1
IC50 = 1.995 nM
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CP0404358
 Compound Info 
US10272079, Compound 99
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C56H78N8O12S2
  1
1
IC50 = 2.512 nM
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CP0447788
 Compound Info 
US10272079, Compound 174
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C54H73Cl4N7O12S2
  1
1
IC50 = 2.512 nM
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CP0458736
 Compound Info 
US10272079, Compound 150
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C50H64Cl4N6O14S2
  1
1
IC50 = 2.512 nM
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CP0576262
 Compound Info 
US10272079, Compound 003
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C52H62Cl4N8O10S2
  1
1
IC50 = 2.512 nM
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CP0557130
 Compound Info 
N,N′-(10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C50H66Cl4N8O10S2
  2
1
IC50 = 3.162 nM
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2
IC50 < 100 nM
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CP0404356
 Compound Info 
US10272079, Compound 108
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C57H81Cl4N11O13S2
  1
1
IC50 = 3.981 nM
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CP0467846
 Compound Info 
US10272079, Compound 148
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C50H64Cl4N6O12S2
  1
1
IC50 = 3.981 nM
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CP0497760
 Compound Info 
US10272079, Compound 98
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C56H76N6O14S2
  1
1
IC50 = 3.981 nM
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CP0390017
 Compound Info 
US10272079, Compound 6
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C52H68Cl4N6O14S2
  1
1
IC50 = 4.467 nM
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CP0415651
 Compound Info 
US10272079, Compound 47
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C58H82N8O12S2
  2
1
IC50 = 4.467 nM
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2
IC50 = 50.12 nM
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CP0387135
 Compound Info 
US10272079, Compound 151
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C51H66Cl4N6O12S2
  1
1
IC50 = 5.012 nM
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CP0491017
 Compound Info 
US10272079, Compound 72
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C62H90N8O14S2
  2
1
IC50 = 5.012 nM
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2
IC50 = 39.81 nM
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CP0390022
 Compound Info 
US10272079, Compound 127
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C52H70Cl4N8O12S2
  1
1
IC50 = 6.31 nM
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CP0467848
 Compound Info 
US10272079, Compound 172
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C80H105Cl6N13O19S3
  1
1
IC50 = 6.31 nM
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CP0848360
 Compound Info 
TENAPANOR HYDROCHLORIDE
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C50H68Cl6N8O10S2
  3
1
IC50 = 6.31 nM
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2
IC50 = 10 nM
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3
IC50 < 100 nM
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CP0569506
 Compound Info 
1-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[3-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]propyl]urea
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C53H72Cl4N8O12S2
  1
1
IC50 = 6.31 nM
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CP0387134
 Compound Info 
US10272079, Compound 149
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C50H64Cl4N6O13S2
  1
1
IC50 = 7.943 nM
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CP0415047
 Compound Info 
US10272079, Compound 100
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C60H76N6O12S2
  1
1
IC50 = 7.943 nM
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CP0415049
 Compound Info 
US10272079, Compound 142
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C84H113Cl6N11O21S3
  1
1
IC50 = 7.943 nM
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CP0864398
 Compound Info 
(S)-N,N'-(2,2'-(2,2'-(2,2'-(1,4-phenylenebis(azanediyl))bis(oxomethylene)bis(azanediyl)bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl))bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)dihydrochloride
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C52H64Cl6N8O10S2
  3
1
IC50 = 7.943 nM
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2
IC50 = 10 nM
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3
IC50 < 100 nM
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CP0559144
 Compound Info 
N,N&#8242;-(2,2&#8242;-(2,2&#8242;-(2,2&#8242;-(1,4-phenylenebis(azanediyl))bis(oxomethylene)bis(azanediyl)bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl))bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C52H62Cl4N8O10S2
  2
1
IC50 = 7.943 nM
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2
IC50 < 100 nM
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CP0431463
 Compound Info 
US10272079, Compound 002
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C50H66Cl4N8O10S2
  2
1
IC50 = 9.333 nM
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2
IC50 = 15.85 nM
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CP0374441
 Compound Info 
US10272079, Compound 67
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C58H78Cl4N8O16S2
  1
1
IC50 = 10 nM
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CP0404353
 Compound Info 
US10272079, Compound 179
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C58H77Cl4N7O15S2
  1
1
IC50 = 10 nM
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CP0914428
 Compound Info 
26-(carboxymethyl)-1-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenoxy)-29-(25-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenoxy)-2,13-dioxo-6,9,17,20,23-pentaoxa-3,12,14-triazapentacosyl)-13,24-dioxo-3,6,9,17,20-pentaoxa-12,14,23,26,29-pentaazahentriacontan-31-oic acid
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C70H98Cl2N18O20
  1
1
IC50 = 10 nM
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CP0545458
 Compound Info 
N-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-2-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]acetamide
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C48H60Cl4N6O11S2
  1
1
IC50 = 10 nM
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CP0572279
 Compound Info 
N,N'-bis[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]butanediamide
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C48H60Cl4N6O10S2
  1
1
IC50 = 10 nM
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CP0390024
 Compound Info 
US10272079, Compound 81
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C54H70Cl4N8O14S2
  1
1
IC50 = 12.59 nM
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CP0415054
 Compound Info 
US10272079, Compound 163
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C80H103Cl6N11O19S3
  1
1
IC50 = 12.59 nM
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CP0871087
 Compound Info 
2,2'-(methylazanediyl)bis(N-(22-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenoxy)-10-oxo-3,6,14,17,20-pentaoxa-9,11-diazadocosyl)acetamide)
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C65H91Cl2N17O16
  1
1
IC50 = 12.59 nM
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CP0871091
 Compound Info 
26-(carboxymethyl)-1-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)-29-(25-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)-2,13-dioxo-6,9,17,20,23-pentaoxa-3,12,14-triazapentacosyl)-13,24-dioxo-3,6,9,17,20-pentaoxa-12,14,23,26,29-pentaazahentriacontan-31-oic acid
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C78H114Cl2N22O18
  1
1
IC50 = 12.59 nM
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CP0550395
 Compound Info 
N1,N4-bis(2-(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)terephthalamide
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C56H68Cl4N6O12S2
  2
1
IC50 = 12.59 nM
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2
IC50 > 10000 nM
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CP0568623
 Compound Info 
1,3-bis[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]urea
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C49H64Cl4N6O11S2
  1
1
IC50 = 12.59 nM
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CP0427511
 Compound Info 
US10272079, Compound 120
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C56H78Cl4N8O13S2
  1
1
IC50 = 15.85 nM
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CP0432131
 Compound Info 
US10272079, Compound 30
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C58H78F4N12O16S2
  1
1
IC50 = 15.85 nM
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CP0447786
 Compound Info 
US10272079, Compound 146
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C84H117Cl6N13O18S3
  1
1
IC50 = 15.85 nM
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CP0546591
 Compound Info 
US10272079, Compound 175
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C79H104Cl6N10O15S3
  1
1
IC50 = 15.85 nM
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CP0873089
 Compound Info 
26-(carboxymethyl)-1-(4-(4-(6-chloro-2-(diaminomethyleneamino)quinazolin-4-yl)phenyl)piperazin-1-yl)-29-(25-(4-(4-(6-chloro-2-(diaminomethyleneamino)quinazolin-4-yl)phenyl)piperazin-1-yl)-2,13-dioxo-6,9,17,20,23-pentaoxa-3,12,14-triazapentacosyl)-13,24-dioxo-3,6,9,17,20-pentaoxa-12,14,23,26,29-pentaazahentriacontan-31-oic acid
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C78H114Cl2N22O18
  1
1
IC50 = 15.85 nM
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CP0877305
 Compound Info 
2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl-[2-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]amino]-N-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]acetamide
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C56H78Cl4N8O13S2
  1
1
IC50 = 15.85 nM
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CP0411218
 Compound Info 
US10272079, Compound 31
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C56H72F4N12O16S2
  1
1
IC50 = 19.95 nM
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CP0415051
 Compound Info 
US10272079, Compound 157
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C79H103Cl6N11O19S4
  1
1
IC50 = 19.95 nM
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CP0431462
 Compound Info 
US10272079, Compound 177
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C83H108Cl6N10O19S3
  1
1
IC50 = 19.95 nM
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CP0446372
 Compound Info 
US10272079, Compound 155
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C83H111Cl6N13O18S3
  1
1
IC50 = 19.95 nM
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CP0845574
 Compound Info 
(2R,3R)-2,3-dihydroxy-N1,N4-bis(2-(2-(2-(2-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)succinamide
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C60H84N6O16S2
  1
1
IC50 = 19.95 nM
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CP0872738
 Compound Info 
2-[2-[carboxymethyl-[2-[2-[2-[2-[2-[2-[2-[2-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]amino]ethyl-[2-[2-[2-[2-[2-[2-[2-[2-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]amino]acetic acid
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C70H98Cl2N18O20
  1
1
IC50 = 19.95 nM
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CP0877307
 Compound Info 
2,2'-(methylazanediyl)bis(N-(22-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)-10-oxo-3,6,14,17,20-pentaoxa-9,11-diazadocosyl)acetamide)
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C73H107Cl2N21O14
  1
1
IC50 = 19.95 nM
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CP0945610
 Compound Info 
2,3-dihydroxy-N,N'-bis[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]butanediamide
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C60H84N6O16S2
  1
1
IC50 = 19.95 nM
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CP0913562
 Compound Info 
N1,N19-bis(2-(2-(2-(2-(4-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
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C68H96Cl2N16O13
  1
1
IC50 = 20.89 nM
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CP0958976
 Compound Info 
N1-(2-(2-(2-(2-(4-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-N19-(2-(2-(2-(2-(4-(4-(6-chloro-2-guanidinoquinazolin-5-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
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C68H96Cl2N16O13
  1
1
IC50 = 20.89 nM
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CP0873090
 Compound Info 
6-(carboxymethyl)-8-oxo-3-(2-oxo-14-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)-6,9,12-trioxa-3-azatetradecyl)-20-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)-12,15,18-trioxa-3,6,9-triazaicosan-1-oic acid
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C66H94N8O18S2
  1
1
IC50 = 22.39 nM
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CP0857135
 Compound Info 
2-[2-[carboxymethyl-[2-oxo-2-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]ethyl]amino]ethyl-[2-oxo-2-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]ethyl]amino]acetic acid
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C66H94N8O18S2
  1
1
IC50 = 22.39 nM
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CP0396066
 Compound Info 
US10272079, Compound 173
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C78H101Cl6N9O16S3
  1
1
IC50 = 25.12 nM
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CP0399536
 Compound Info 
US10272079, Compound 97
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C52H68Cl2N6O12S2
  1
1
IC50 = 25.12 nM
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CP0440461
 Compound Info 
US10272079, Compound 139
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C80H102Cl6N10O19S3
  1
1
IC50 = 25.12 nM
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CP0864961
 Compound Info 
(S)-2-(3-(1,25-bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-13-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-10,16-dioxo-3,6,20,23-tetraoxa-9,17-diazapentacosan-13-yl)ureido)succinic acid
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C81H103Cl6N11O20S3
  1
1
IC50 = 25.12 nM
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CP0867115
 Compound Info 
1-[2-[2-[2-[2-[4-(6-chloro-2-guanidino-quinazolin-4-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[4-[2-[2-[2-[2-[2-[2-[2-[4-(6-chloro-2-guanidino-quinazolin-4-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethylcarbamoylamino]butylcarbamoylamino]ethoxy]ethoxy]ethyl]urea
   Show/Hide
C66H94Cl2N18O16
  1
1
IC50 = 25.12 nM
 Bioactivity Info 
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CP0875557
 Compound Info 
1-[2-[2-[2-[4-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenyl]piperazin-1-yl]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[4-[2-[2-[2-[2-[2-[2-[4-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenyl]piperazin-1-yl]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethylcarbamoylamino]butylcarbamoylamino]ethoxy]ethoxy]ethyl]urea
   Show/Hide
C70H102Cl2N22O12
  1
1
IC50 = 25.12 nM
 Bioactivity Info 
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CP0903014
 Compound Info 
1-[2-[2-[2-[4-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenyl]piperazin-1-yl]ethoxy]ethoxy]ethyl]-3-[2-[2-[[4-[2-[2-[2-[2-[2-[2-[4-[3-(6-chloro-2-guanidino-quinazolin-4-yl)phenyl]piperazin-1-yl]ethoxy]ethoxy]ethylcarbamoylamino]ethoxy]ethoxy]ethylcarbamoylamino]butylcarbamoylamino]methoxy]ethoxy]ethyl]urea
   Show/Hide
C69H100Cl2N22O12
  1
1
IC50 = 25.12 nM
 Bioactivity Info 
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CP0569542
 Compound Info 
N-[2-[2-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
   Show/Hide
C51H68Cl4N6O13S2
  1
1
IC50 = 25.12 nM
 Bioactivity Info 
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CP0571697
 Compound Info 
N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)terephthalamide
   Show/Hide
C56H68Cl4N6O12S2
  1
1
IC50 = 25.12 nM
 Bioactivity Info 
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CP0872737
 Compound Info 
2-[2-[carboxymethyl-[2-oxo-2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]ethyl]amino]ethyl-[2-oxo-2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]ethyl]amino]acetic acid
   Show/Hide
C62H86N8O16S2
  1
1
IC50 = 28.18 nM
 Bioactivity Info 
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CP0431669
 Compound Info 
US10272079, Compound 164
   Show/Hide
C79H101Cl6N11O18S3
  1
1
IC50 = 29.51 nM
 Bioactivity Info 
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CP0389176
 Compound Info 
US10272079, Compound 27
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C60H78F4N12O20S2
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0404361
 Compound Info 
US10272079, Compound 29
   Show/Hide
C56H74F4N12O16S2
  1
1
IC50 = 31.62 nM
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CP0409699
 Compound Info 
US10272079, Compound 176
   Show/Hide
C83H111Cl6N11O16S3
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0434867
 Compound Info 
US10272079, Compound 117
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C64H84N6O14S2
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0434877
 Compound Info 
US10272079, Compound 37
   Show/Hide
C23H29ClN6O4
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0434987
 Compound Info 
US10272079, Compound 84
   Show/Hide
C78H101Cl6N9O18S3
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0438104
 Compound Info 
US10272079, Compound 96
   Show/Hide
C52H68Cl2N6O11S2
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0470943
 Compound Info 
US10272079, Compound 123
   Show/Hide
C80H102Cl6N10O18S3
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0490143
 Compound Info 
US10272079, Compound 26
   Show/Hide
C58H76F4N10O20S2
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0911853
 Compound Info 
2,2'-(methylazanediyl)bis(N-(22-(4-(4-(6-chloro-2-(diaminomethyleneamino)quinazolin-4-yl)phenyl)piperazin-1-yl)-10-oxo-3,6,14,17,20-pentaoxa-9,11-diazadocosyl)acetamide)
   Show/Hide
C73H107Cl2N21O14
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0913933
 Compound Info 
2,2'-(methylazanediyl)bis(N-(22-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenoxy)-10-oxo-3,6,14,17,20-pentaoxa-9,11-diazadocosyl)acetamide)
   Show/Hide
C65H91Cl2N17O16
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0911854
 Compound Info 
4-[[4-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-1-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]-1-[3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-3-oxo-propyl]-4-oxo-butyl]amino]-4-oxo-butanoic acid
   Show/Hide
C79H100Cl6N10O18S3
  1
1
IC50 = 31.62 nM
 Bioactivity Info 
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CP0569571
 Compound Info 
N,N&#8242;-(13,20-dioxo-3,6,9,24,27,30-hexaoxa-12,14,19,21-tetraazadotriacontane-1,32-diyl)bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C54H74Cl4N8O12S2
  2
1
IC50 = 31.62 nM
 Bioactivity Info 
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2
IC50 < 100 nM
 Bioactivity Info 
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CP0494901
 Compound Info 
US10272079, Compound 50
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C57H79N7O12S2
  1
1
IC50 = 35.48 nM
 Bioactivity Info 
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CP0875560
 Compound Info 
N1,N19-bis(2-(2-(2-(2-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
   Show/Hide
C70H104N6O19S2
  1
1
IC50 = 35.48 nM
 Bioactivity Info 
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CP0877306
 Compound Info 
2-[methyl-[2-oxo-2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]ethyl]amino]-N-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethyl]acetamide
   Show/Hide
C57H79N7O12S2
  1
1
IC50 = 35.48 nM
 Bioactivity Info 
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CP0900167
 Compound Info 
3-[2-[2-[2-[2-[3-oxo-3-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]propoxy]ethoxy]ethoxy]ethoxy]ethoxy]-N-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]propanamide
   Show/Hide
C70H104N6O19S2
  1
1
IC50 = 35.48 nM
 Bioactivity Info 
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CP0386639
 Compound Info 
US10272079, Compound 109
   Show/Hide
C79H108Cl6N13O15S3+
  1
1
IC50 = 39.81 nM
 Bioactivity Info 
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CP0390021
 Compound Info 
US10272079, Compound 135
   Show/Hide
C58H80Cl4N10O12S2
  1
1
IC50 = 39.81 nM
 Bioactivity Info 
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CP0411224
 Compound Info 
US10272079, Compound 118
   Show/Hide
C64H84N6O14S2
  1
1
IC50 = 39.81 nM
 Bioactivity Info 
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CP0425257
 Compound Info 
(2R,3S,4R,5R)-N-[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]-2,3,4,5,6-pentahydroxyhexanamide
   Show/Hide
C22H26Cl2N2O6
  1
1
IC50 = 39.81 nM
 Bioactivity Info 
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CP0873091
 Compound Info 
(S)-N,N'-(18-(1-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-13-oxo-3,6,9-trioxa-12,14-diazaheptadecan-17-yl)-13,23-dioxo-3,6,9,27,30,33-hexaoxa-12,14,18,22,24-pentaazapentatriacontane-1,35-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
   Show/Hide
C84H117Cl6N13O18S3
  1
1
IC50 = 39.81 nM
 Bioactivity Info 
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CP0877308
 Compound Info 
2,2'-(methylazanediyl)bis(N-(19-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)-10-oxo-3,6,14,17-tetraoxa-9,11-diazanonadecyl)acetamide)
   Show/Hide
C69H99Cl2N21O12
  1
1
IC50 = 39.81 nM
 Bioactivity Info 
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CP0390018
 Compound Info 
US10272079, Compound 001
   Show/Hide
C22H26Cl2N2O6
  1
1
IC50 = 39.81 nM
 Bioactivity Info 
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CP0852587
 Compound Info 
1-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea
   Show/Hide
C62H90N8O14S2
  1
1
IC50 = 39.81 nM
 Bioactivity Info 
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CP0468429
 Compound Info 
N,N'-bis[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]butanediamide
   Show/Hide
C48H60Cl4N6O10S2
  2
1
IC50 = 39.81 nM
 Bioactivity Info 
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2
IC50 < 100 nM
 Bioactivity Info 
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CP0562995
 Compound Info 
N-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-2-[2-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]acetamide
   Show/Hide
C48H60Cl4N6O11S2
  2
1
IC50 = 39.81 nM
 Bioactivity Info 
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2
IC50 = 1000 nM
 Bioactivity Info 
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CP0864397
 Compound Info 
(S)-N,N'-(15-amino-15-(1-(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-10-oxo-3,6-dioxa-9,11-diazatetradecan-14-yl)-10,20-dioxo-3,6,24,27-tetraoxa-9,11,19,21-tetraazanonacosane-1,29-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
   Show/Hide
C79H107Cl6N13O15S3
  1
1
IC50 = 44.67 nM
 Bioactivity Info 
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CP0913934
 Compound Info 
2,2'-(methylazanediyl)bis(N-(2-(2-(2-(2-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)acetamide)
   Show/Hide
C61H87N7O14S2
  1
1
IC50 = 44.67 nM
 Bioactivity Info 
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CP0554452
 Compound Info 
US10272079, Compound 168
   Show/Hide
C76H101Cl6N13O15S3
  1
1
IC50 = 44.67 nM
 Bioactivity Info 
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CP0900165
 Compound Info 
2-[methyl-[2-oxo-2-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]ethyl]amino]-N-[2-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]acetamide
   Show/Hide
C61H87N7O14S2
  1
1
IC50 = 44.67 nM
 Bioactivity Info 
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CP0431405
 Compound Info 
US10272079, Compound 22
   Show/Hide
C24H33Cl2N3O5S
  2
1
IC50 = 45.71 nM
 Bioactivity Info 
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2
IC50 = 794.33 nM
 Bioactivity Info 
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CP0404360
 Compound Info 
US10272079, Compound 005
   Show/Hide
C50H66Cl4N8O10S2
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0432126
 Compound Info 
US10272079, Compound 20
   Show/Hide
C62H86Cl2N18O10
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0447785
 Compound Info 
US10272079, Compound 137
   Show/Hide
C81H104Cl6N10O18S3
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0458732
 Compound Info 
US10272079, Compound 138
   Show/Hide
C81H105Cl6N11O18S3
  1
1
IC50 = 50.12 nM
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CP0863055
 Compound Info 
(R)-N,N'-(10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosane-1,26-diyl)bis(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)dihydrochloride
   Show/Hide
C50H68Cl6N8O10S2
  2
1
IC50 = 50.12 nM
 Bioactivity Info 
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2
IC50 = 2511.89 nM
 Bioactivity Info 
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CP0867116
 Compound Info 
N1,N19-bis(2-(2-(2-(4-((1S,2S)-2-(piperidin-1-yl)-2,3-dihydro-1H-inden-1-yloxy)phenylsulfonamido)ethoxy)ethoxy)ethyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
   Show/Hide
C66H96N6O17S2
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0875556
 Compound Info 
(E)-N-(diaminomethylene)-3-(4-(4-(N-(1-(4-(4-((E)-3-(diaminomethyleneamino)-2-methyl-3-oxoprop-1-enyl)-2,6-difluorophenoxy)phenylsulfonamido)-13,17-dioxo-3,6,9,15,21,25,28-heptaoxa-12,18-diazatriacontan-30-yl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylamide
   Show/Hide
C55H70F4N10O17S2
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0877304
 Compound Info 
N1,N25-bis(2-(2-(2-(2-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16,19,22-heptaoxapentacosane-1,25-diamide
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C72H104Cl2N16O15
  1
1
IC50 = 50.12 nM
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CP0883789
 Compound Info 
17-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-5,5-bis(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-3,8-dioxo-12,15-dioxa-2,4,9-triazaheptadecylphosphonic acid
   Show/Hide
C78H102Cl6N11O19PS3
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0431668
 Compound Info 
US10272079, Compound 162
   Show/Hide
C79H105Cl6N12O19PS3
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0434880
 Compound Info 
US10272079, Compound 15
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C54H68F4N10O17S2
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0849850
 Compound Info 
1-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea Dihydrochloride
   Show/Hide
C50H68Cl6N8O10S2
  2
1
IC50 = 50.12 nM
 Bioactivity Info 
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2
IC50 = 2511.89 nM
 Bioactivity Info 
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CP0900166
 Compound Info 
3-[2-[2-[2-[2-[3-oxo-3-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]propoxy]ethoxy]ethoxy]ethoxy]ethoxy]-N-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethyl]propanamide
   Show/Hide
C66H96N6O17S2
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0954102
 Compound Info 
1-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[4-[2-(1-piperidyl)indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea
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C58H82N8O12S2
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0572302
 Compound Info 
3-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]propane-1-sulfonic acid
   Show/Hide
C19H22Cl2N2O5S2
  1
1
IC50 = 50.12 nM
 Bioactivity Info 
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CP0440489
 Compound Info 
US10272079, Compound 143
   Show/Hide
C83H111Cl6N11O21S3
  1
1
IC50 = 56.23 nM
 Bioactivity Info 
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CP0404355
 Compound Info 
US10272079, Compound 144
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C83H110Cl6N12O17S3
  1
1
IC50 = 63.1 nM
 Bioactivity Info 
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CP0415052
 Compound Info 
US10272079, Compound 159
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C81H106Cl6N12O18S3
  1
1
IC50 = 63.1 nM
 Bioactivity Info 
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CP0477877
 Compound Info 
US10272079, Compound 90
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C82H110Cl6N10O18S3
  1
1
IC50 = 63.1 nM
 Bioactivity Info 
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CP0851375
 Compound Info 
3,12-bis(14-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-2-oxo-6,9,12-trioxa-3-azatetradecyl)-N1,N14-bis(2-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-diamide
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C110H148Cl8N14O26S4
  1
1
IC50 = 63.1 nM
 Bioactivity Info 
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CP0550392
 Compound Info 
3-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]propylphosphonic acid
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C19H23Cl2N2O5PS
  1
1
IC50 = 63.1 nM
 Bioactivity Info 
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CP0550397
 Compound Info 
N-[2-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
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C51H68Cl4N6O13S2
  1
1
IC50 = 63.1 nM
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CP0861099
 Compound Info 
N1,N7-bis(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-4-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-4-(dimethylamino)heptanediamide
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C78H102Cl6N10O15S3
  1
1
IC50 = 67.61 nM
 Bioactivity Info 
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CP0404359
 Compound Info 
US10272079, Compound 57
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C78H102Cl6N10O18S3
  1
1
IC50 = 79.43 nM
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CP0415055
 Compound Info 
US10272079, Compound 178
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C80H105Cl6N11O18S3
  1
1
IC50 = 79.43 nM
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CP0446392
 Compound Info 
US10272079, Compound 17
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C54H68Cl2N16O8
  1
1
IC50 = 79.43 nM
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CP0510136
 Compound Info 
US10272079, Compound 89
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C85H114Cl6N10O19S3
  1
1
IC50 = 79.43 nM
 Bioactivity Info 
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CP0548233
 Compound Info 
US10272079, Compound 128
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C80H105Cl6N11O16S3
  1
1
IC50 = 79.43 nM
 Bioactivity Info 
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CP0883790
 Compound Info 
N1,N7-bis(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-4-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-4-(4-(2-(2-hydroxyethoxy)ethyl)piperazine-1-carboxamido)heptanediamide
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C85H114Cl6N12O18S3
  1
1
IC50 = 79.43 nM
 Bioactivity Info 
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CP0880615
 Compound Info 
N,N'-bis[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-4-[3-[2-[2-[2-[[4-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]propyl]-4-[[4-[2-(2-hydroxyethoxy)ethyl]piperazine-1-carbonyl]amino]heptanediamide
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C85H116Cl6N12O17S3
  1
1
IC50 = 79.43 nM
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CP0529374
 Compound Info 
N,N&#8242;-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-diazapentacosane-1,25-diyl)bis(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C49H64Cl4N6O11S2
  2
1
IC50 = 79.43 nM
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2
IC50 < 100 nM
 Bioactivity Info 
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CP0415653
 Compound Info 
US10272079, Compound 88
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C76H98Cl6N10O15S3
  1
1
IC50 = 85.11 nM
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CP0389073
 Compound Info 
US10272079, Compound 14
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C58H78F4N12O18S2
  1
1
IC50 = 100 nM
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CP0390020
 Compound Info 
US10272079, Compound 147
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C79H107Cl6N13O15S3
  1
1
IC50 = 100 nM
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CP0425002
 Compound Info 
US10272079, Compound 19
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C25H33ClN8O2
  1
1
IC50 = 100 nM
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CP0432134
 Compound Info 
US10272079, Compound 61
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C78H101Cl6N9O19S3
  1
1
IC50 = 100 nM
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CP0848305
 Compound Info 
(S)-N,N'-(15-(2-(3-((S)-5,7-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)phenylsulfonyl)-12-oxo-5,8-dioxa-2,11,13-triazahexadecan-16-yl)-10,20-dioxo-3,6,24,27-tetraoxa-9,11,15,19,21-pentaazanonacosane-1,29-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-methylbenzenesulfonamide)
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C81H111Cl6N13O15S3
  1
1
IC50 = 100 nM
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CP0466745
 Compound Info 
(S or R)&#151;N,N&#8242;-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-diazapentacosane-1,25-diyl)bis(4-((S or R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C49H64Cl4N6O11S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0468395
 Compound Info 
N1,N4-bis(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C48H60Cl4N6O12S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0540062
 Compound Info 
N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C52H68Cl4N6O14S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0543028
 Compound Info 
N,N&#8242;-(13,20 dioxo-3, 6, 9, 24, 27, 30-hexaoxa-12, 21-diazadotricontane-1,32-diyl)bis[(E)-N-(diaminomethylene)-3-(3,5-difluoro-4-(4-sulfamoylphenoxy)phenyl)-2-methylacrylamide]
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C58H76F4N10O16S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0556099
 Compound Info 
N1,N2-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)phthalamide
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C56H68Cl4N6O12S2
  1
1
IC50 < 100 nM
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CP0556101
 Compound Info 
(S or R)&#151;N,N&#8242;-(13,20-dioxo-3,6,9,24,27,30-hexaoxa-12,14,19,21-tetraazadotriacontane-1,32-diyl)bis(4-((S or R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C54H74Cl4N8O12S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0562996
 Compound Info 
N1,N4-bis(2-(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C52H68Cl4N6O14S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0562997
 Compound Info 
2,2&#8242;-oxybis(N-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)acetamide)
   Show/Hide
C48H60Cl4N6O11S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0562998
 Compound Info 
(2R,3S)&#151;N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C52H68Cl4N6O14S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0572959
 Compound Info 
N1,N4-bis(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)succinamide
   Show/Hide
C48H60Cl4N6O10S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0572960
 Compound Info 
N1,N3,N5-tris(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)benzene-1,3,5-tricarboxamide
   Show/Hide
C81H99Cl6N9O18S3
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0897725
 Compound Info 
N,N'-(butane-1,4-diyl)bis(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)acetamido)acetamido)acetamide)
   Show/Hide
C48H56Cl4N10O10S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0899491
 Compound Info 
N1,N31-bis(2-(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16,19,22,25,28-nonaoxahentriacontane-1,31-diide
   Show/Hide
C70H104Cl4N6O21S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0900688
 Compound Info 
(2S,3S)-N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C52H68Cl4N6O14S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0947349
 Compound Info 
N1,N4-bis(2-(2-(2-(2-(3-((S/R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C52H68Cl4N6O14S2
  1
1
IC50 < 100 nM
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CP0947350
 Compound Info 
(S/R)-N,N'-(13,20-dioxo-3,6,9,24,27,30-hexaoxa-12,14,19,21-tetraazadotriacontane-1,32-diyl)bis(((S/R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C54H74Cl4N8O12S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0957843
 Compound Info 
N,N'-(2,2'-(2,2'-(2,2'-(1,4-phenylenebis(methylene))tobis(azanediyl)bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl))bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C52H64Cl4N6O8S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0957844
 Compound Info 
N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)terephthalamide
   Show/Hide
C56H68Cl4N6O12S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0957890
 Compound Info 
2,2'-oxybis(N-(2-(2-(2-(4-((S/R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)acetamide)bis-hydrochloride salt
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C48H62Cl6N6O11S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0957955
 Compound Info 
N1,N4-bis(2-(2-(2-(4-((S/R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)succinamide bis-hydrochloride salt
   Show/Hide
C48H62Cl6N6O10S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0958993
 Compound Info 
3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(2-(2-(2-(2-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)ethoxy)ethoxy)ethoxy)ethyl)benzene sulfonamide
   Show/Hide
C33H44Cl2N8O7S
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0961128
 Compound Info 
(2R,3R)-N1,N4-bis(2-(2-(2-(2-(4-(4-((E)-3-(diaminomethyleneamino)-2-methyl-3-oxoprop-1-enyl)-2,6-difluorophenoxy)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C54H68F4N10O18S2
  1
1
IC50 < 100 nM
 Bioactivity Info 
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CP0487225
 Compound Info 
US10272079, Compound 106
   Show/Hide
C81H111Cl6N13O15S3
  1
1
IC50 = 100 nM
 Bioactivity Info 
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CP0572958
 Compound Info 
N,N&#8242;-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-diazapentacosane-1,25-diyl)bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
   Show/Hide
C49H64Cl4N6O11S2
  2
1
IC50 = 100 nM
 Bioactivity Info 
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2
IC50 = 1000 nM
 Bioactivity Info 
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CP0573164
 Compound Info 
2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]acetic acid
   Show/Hide
C18H18Cl2N2O4S
  1
1
IC50 = 100 nM
 Bioactivity Info 
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CP0573166
 Compound Info 
N-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[[4-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
   Show/Hide
C47H60Cl4N6O11S2
  1
1
IC50 = 100 nM
 Bioactivity Info 
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CP0389178
 Compound Info 
US10272079, Compound 11
   Show/Hide
C21H25ClN6O3
  1
1
IC50 = 112.2 nM
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CP0389072
 Compound Info 
US10272079, Compound 18
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C27H37ClN8O3
  1
1
IC50 = 125.89 nM
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CP0389179
 Compound Info 
US10272079, Compound 5
   Show/Hide
C54H68F4N10O18S2
  1
1
IC50 = 125.89 nM
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CP0404352
 Compound Info 
US10272079, Compound 4
   Show/Hide
C25H33F2N5O7S
  2
1
IC50 = 125.89 nM
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2
IC50 = 1000 nM
 Bioactivity Info 
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CP0425260
 Compound Info 
US10272079, Compound 59
   Show/Hide
C81H111Cl6N13O18S3
  1
1
IC50 = 125.89 nM
 Bioactivity Info 
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CP0432124
 Compound Info 
US10272079, Compound 8
   Show/Hide
C21H26ClN7O4S
  1
1
IC50 = 125.89 nM
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CP0487224
 Compound Info 
US10272079, Compound 56
   Show/Hide
C81H99Cl6N9O18S3
  1
1
IC50 = 125.89 nM
 Bioactivity Info 
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CP0497762
 Compound Info 
US10272079, Compound 107
   Show/Hide
C81H111Cl6N13O15S3
  1
1
IC50 = 125.89 nM
 Bioactivity Info 
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CP0864960
 Compound Info 
(1S,2S)-2-(1,25-bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-13-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-10,16-dioxo-3,6,20,23-tetraoxa-9,17-diazapentacosan-13-ylcarbamoyl)cyclohexanecarboxylic acid
   Show/Hide
C84H108Cl6N10O18S3
  1
1
IC50 = 125.89 nM
 Bioactivity Info 
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CP0883781
 Compound Info 
N1-(2-(2-(2-(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-N7-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-4-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)-4-(4-methylpiperazine-1-carboxamido)heptanediamide
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C82H108Cl6N12O16S3
  1
1
IC50 = 125.89 nM
 Bioactivity Info 
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CP0434865
 Compound Info 
US10272079, Compound 153
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C82H108Cl6N12O16S3
  1
1
IC50 = 125.89 nM
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CP0857138
 Compound Info 
(1S,2S)-2-[[1,1-bis[3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-3-oxo-propyl]-4-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethylamino]-4-oxo-butyl]carbamoyl]cyclohexanecarboxylic acid
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C82H104Cl6N10O17S3
  1
1
IC50 = 125.89 nM
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CP0900164
 Compound Info 
3-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-1-[3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoyl-[3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoyl-methyl-amino]propyl]amino]propyl]-1-methyl-urea
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C77H102Cl6N12O15S3
  1
1
IC50 = 125.89 nM
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CP0945613
 Compound Info 
1-[2-[bis[2-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]ethyl]amino]ethyl]-3-[2-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]urea
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C81H111Cl6N13O18S3
  1
1
IC50 = 125.89 nM
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CP0579777
 Compound Info 
N-[2-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[2-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethoxy]ethylamino]-2,3-dihydroxypropanamide
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C47H60Cl4N6O11S2
  1
1
IC50 = 125.89 nM
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CP0875165
 Compound Info 
N1,N19-bis(2-(2-(2-(2-(4-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
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C68H96Cl2N16O13
  1
1
IC50 = 134.9 nM
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CP0875166
 Compound Info 
(S)-N-(2-(2-(2-(3-(6-chloro-2-guanidinoquinazolin-4-yl)phenoxy)ethoxy)ethoxy)ethyl)-2-(14-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-2-oxo-6,9,12-trioxa-3-azatetradecyloxy)acetamide
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C49H60Cl3N9O11S
  1
1
IC50 = 141.25 nM
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CP0389071
 Compound Info 
US10272079, Compound 25
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C49H60Cl3N9O11S
  1
1
IC50 = 141.25 nM
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CP0415050
 Compound Info 
US10272079, Compound 154
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C81H102Cl6N12O16S3
  1
1
IC50 = 158.49 nM
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CP0871220
 Compound Info 
N1,N1,N19,N19-tetrakis(13-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-4-oxo-8,11-dioxa-3,5-diazatridecyl)-4,7,10,13,16-pentaoxanonadecane-1,19-diamide
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C114H156Cl8N18O27S4
  1
1
IC50 = 158.49 nM
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CP0860425
 Compound Info 
4-[2-[2-[2-[3-[bis[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]ethyl]amino]-3-oxo-propoxy]ethoxy]ethoxy]ethoxy]-N,N-bis[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]ethyl]butanamide
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C113H154Cl8N18O26S4
  1
1
IC50 = 158.49 nM
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CP0420758
 Compound Info 
US10272079, Compound 2
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C19H22Cl2N2O3S
  1
1
IC50 = 199.53 nM
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CP0431403
 Compound Info 
US10272079, Compound 16
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C25H33ClN8O2
  1
1
IC50 = 199.53 nM
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CP0467849
 Compound Info 
US10272079, Compound 70
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C96H135Cl6N21O18S3
  1
1
IC50 = 199.53 nM
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CP0471883
 Compound Info 
US10272079, Compound 13
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C58H72F4N10O14S2
  1
1
IC50 = 199.53 nM
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CP0522813
 Compound Info 
US10272079, Compound 104
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C27H35Cl2N3O6S
  1
1
IC50 = 199.53 nM
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CP0559119
 Compound Info 
US10272079, Compound 103
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C27H37Cl2N3O6S
  1
1
IC50 = 199.53 nM
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CP0885290
 Compound Info 
4-(2-(1H-tetrazol-5-yl)acetamido)-N1,N7-bis(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-4-(3-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethylamino)-3-oxopropyl)heptanediamide
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C79H100Cl6N14O16S3
  1
1
IC50 = 199.53 nM
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CP0434861
 Compound Info 
US10272079, Compound 10
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C21H25ClN6O3
  1
1
IC50 = 223.87 nM
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CP0420760
 Compound Info 
US10272079, Compound 69
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C93H126Cl6N18O18S3
  1
1
IC50 = 251.19 nM
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CP0434883
 Compound Info 
US10272079, Compound 1
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C16H16Cl2N2O2S
  1
1
IC50 = 251.19 nM
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CP0560831
 Compound Info 
US10272079, Compound 102
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C43H69Cl2N3O12S
  1
1
IC50 = 251.19 nM
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CP0915642
 Compound Info 
N1,N1,N31,N31-tetrakis(13-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-4-oxo-8,11-dioxa-3,5-diazatridecyl)-4,7,10,13,16,19,22,25,28-nonaoxahentriacontane-1,31-diamide
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C122H172Cl8N18O31S4
  1
1
IC50 = 251.19 nM
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CP0945606
 Compound Info 
2-[3-[2-[2-(2-octoxyethoxy)ethoxy]ethoxy]propoxy]ethyl N-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethyl]carbamate
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C44H71Cl2N3O12S
  1
1
IC50 = 251.19 nM
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CP0411800
 Compound Info 
US10272079, Compound 134
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C78H102Cl6N10O15S3
  1
1
IC50 = 316.23 nM
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CP0446394
 Compound Info 
US10272079, Compound 169
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C78H99Cl6N9O16S3
  1
1
IC50 = 316.23 nM
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CP0447784
 Compound Info 
US10272079, Compound 133
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C77H99Cl6N11O16S3
  1
1
IC50 = 316.23 nM
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CP0864448
 Compound Info 
3,3',3''-nitrilotris(N-(2-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)propanamide)
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C81H108Cl6N10O18S3
  1
1
IC50 = 316.23 nM
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CP0875164
 Compound Info 
N-(diaminomethylene)-3-[4-[4-[2-[2-[2-[2-[[2-[[2-[2-[2-[2-[2-[[4-[2,6-difluoro-4-[3-guanidino-2-methyl-3-oxo-prop-1-enyl]phenoxy]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]-methyl-amino]acetyl]amino]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]phenoxy]-3,5-difluoro-phenyl]-2-methyl-prop-2-enamide
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C55H71F4N11O16S2
  1
1
IC50 = 316.23 nM
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CP0916649
 Compound Info 
2,2'-((1R,2R)-2-(1-(14-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-2-oxo-6,9,12-trioxa-3-azatetradecyl)-3-(2-(2-(2-(2-(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)ureido)cyclohexylazanediyl)bis(N-(2-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)acetamide)
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C109H144Cl8N14O24S4
  1
1
IC50 = 316.23 nM
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CP0434884
 Compound Info 
US10272079, Compound 71
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C109H144Cl8N14O24S4
  1
1
IC50 = 316.23 nM
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CP0866811
 Compound Info 
3-[bis[3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonyl-methyl-amino]ethoxy]ethoxy]ethylamino]-3-oxo-propyl]amino]-N-[2-[2-[2-[[4-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonyl-methyl-amino]ethoxy]ethoxy]ethyl]propanamide
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C78H102Cl6N10O15S3
  1
1
IC50 = 316.23 nM
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CP0911879
 Compound Info 
N-(diaminomethylene)-3-[4-[4-[2-[2-[2-[2-[[2-[[2-[2-[2-[2-[2-[[4-[2,6-difluoro-4-[3-guanidino-2-methyl-3-oxo-prop-1-enyl]phenoxy]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]-methyl-amino]acetyl]amino]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]phenoxy]-3,5-difluoro-phenyl]-2-methyl-prop-2-enamide
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C55H71F4N11O16S2
  1
1
IC50 = 316.23 nM
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CP0958975
 Compound Info 
1-[3,3-bis[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]ethyl]-4-oxo-pentyl]-3-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]urea
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C78H102Cl6N12O16S3
  1
1
IC50 = 316.23 nM
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CP0565542
 Compound Info 
N1,N4-bis(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)terephthalamide
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C52H60Cl4N6O10S2
  2
1
IC50 = 398.11 nM
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2
IC50 > 10000 nM
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CP0415045
 Compound Info 
US10272079, Compound 60
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C26H37N3O5S
  1
1
IC50 = 446.68 nM
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CP0411258
 Compound Info 
US10272079, Compound 7
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C21H26ClN7O4S
  1
1
IC50 = 501.19 nM
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CP0425274
 Compound Info 
US10272079, Compound 58
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C112H152Cl8N16O24S4
  1
1
IC50 = 501.19 nM
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CP0444143
 Compound Info 
US10272079, Compound 74
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C72H90Cl6N10O15S3
  1
1
IC50 = 501.19 nM
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CP0888102
 Compound Info 
2,2'-(20-(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-3,6-bis(14-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-2-oxo-6,9,12-trioxa-3-azatetradecyl)-8-oxo-12,15,18-trioxa-3,6,9-triazaicosylazanediyl)bis(N-(2-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)acetamide)
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C134H178Cl10N18O30S5
  1
1
IC50 = 501.19 nM
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CP0536231
 Compound Info 
US10272079, Compound 75
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C134H178Cl10N18O30S5
  1
1
IC50 = 501.19 nM
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CP0911880
 Compound Info 
2-[4,10-bis[2-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]-7-[2-[2-[2-[2-[2-[[3-[(4S)-6,8-dichloro-1,2,3,4-tetrahydroisoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxo-ethyl]-1,4,7,10-tetrazacyclododec-1-yl]-N-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]acetamide
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C109H146Cl8N16O23S4
  1
1
IC50 = 501.19 nM
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CP0569106
 Compound Info 
N-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethyl]-3-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethylamino]-2,3-dihydroxypropanamide
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C39H44Cl4N6O7S2
  1
1
IC50 = 501.19 nM
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CP0434873
 Compound Info 
US10272079, Compound 77
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C78H105Cl6N13O15S3
  1
1
IC50 = 562.34 nM
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CP0374426
 Compound Info 
US10272079, Compound 122
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C77H100Cl6N10O17S4
  1
1
IC50 = 630.96 nM
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CP0434882
 Compound Info 
US10272079, Compound 12
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C23H30ClN7O5S
  1
1
IC50 = 794.33 nM
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CP0467845
 Compound Info 
US10272079, Compound 130
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C78H101Cl6N11O16S3
  1
1
IC50 = 794.33 nM
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CP0869154
 Compound Info 
(S)-N,N'-(15-(1-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-9-methyl-10-oxo-3,6-dioxa-9,11-diazatetradecan-14-yl)-9,21-dimethyl-10,20-dioxo-3,6,24,27-tetraoxa-9,11,15,19,21-pentaazanonacosane-1,29-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C81H111Cl6N13O15S3
  1
1
IC50 = 794.33 nM
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CP0947280
 Compound Info 
2,2'-(methylazanediyl)bis(N-(2-(2-(2-(2-(4-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)acetamide)
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C59H79Cl2N17O8
  1
1
IC50 = 794.33 nM
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CP0952974
 Compound Info 
2-((14-(4-(4-(6-chloro-2-guanidinoquinazolin-4-yl)phenyl)piperazin-1-yl)-2-oxo-6,9,12-trioxa-3-azatetradecyl)(methyl)amino)-N-(2-(2-(3-(2-(4-(4-(6-chloro-2-guanidinoquinazolin-5-yl)phenyl)piperazin-1-yl)ethoxy)propoxy)ethoxy)ethyl)acetamide
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C60H81Cl2N17O8
  1
1
IC50 = 794.33 nM
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CP0380071
 Compound Info 
US10272079, Compound 78
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C72H89Cl6N9O16S3
  1
1
IC50 = 1000 nM
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CP0420506
 Compound Info 
US10272079, Compound 132
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C84H117Cl6N13O15S3
  1
1
IC50 = 1000 nM
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CP0377090
 Compound Info 
2-(6-chloro-4-(3-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)quinazolin-2-yl)guanidine
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C21H24ClN7O
  1
1
IC50 = 1000 nM
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CP0466744
 Compound Info 
N,N&#8242;-(13-oxo-3,6,9,17,20,23-hexaoxa-12,14-diazapentacosane-1,25-diyl)bis[(E)-N-(diaminomethylene)-3-(3,5-difluoro-4-(4-sulfamoylphenoxy)phenyl)-2-methylacrylamide]
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C53H66F4N4O17S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0468426
 Compound Info 
4-(4-(6-chloro-2-(diaminomethyleneamino)quinazolin-4-yl)phenyl)piperazine-1-carboximidamide
   Show/Hide
C20H22ClN9
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0468427
 Compound Info 
N1,N31-bis(32-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontyl)-4,7,10,13,16,19,22,25,28-nonaoxahentriacontane-1,31-diamide
   Show/Hide
C98H160Cl4N6O35S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0468428
 Compound Info 
N1,N3-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)isophthalamide
   Show/Hide
C56H68Cl4N6O12S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0508367
 Compound Info 
2-(6-chloro-4-(4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)quinazolin-2-yl)guanidine
   Show/Hide
C21H24ClN7O
  1
1
IC50 = 1000 nM
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CP0525595
 Compound Info 
2-(4-(3-(4-(3-guanidinopropyl)piperazin-1-yl)phenyl)-6-chloroquinazolin-2-yl)guanidine
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C23H29ClN10
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0556919
 Compound Info 
(2R,3R)&#151;N1,N4-bis(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C48H60Cl4N6O12S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0557128
 Compound Info 
1-(4-(3-(4-(3-aminopropyl)piperazin-1-yl)phenyl)-6-chloroquinazolin-2-yl)guanidine
   Show/Hide
C22H27ClN8
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0557129
 Compound Info 
2R,3R)&#151;N1,N4-bis(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C48H60Cl4N6O12S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0559143
 Compound Info 
(E)-3-(4-(4-(N-(20-amino-3,6,9,12,15,18-hexaoxaicosyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-N-(diaminomethylene)-2-methylacrylamide
   Show/Hide
C31H45F2N5O10S
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0564995
 Compound Info 
2,2&#8242;,2&#8243;-nitrilotris(N-(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)acetamide)
   Show/Hide
C78H102Cl6N10O18S3
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0572957
 Compound Info 
N1,N8-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)octanediamide
   Show/Hide
C56H76Cl4N6O12S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0847226
 Compound Info 
N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide
   Show/Hide
C24H33Cl2N3O5S
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0847227
 Compound Info 
N1,N4-bis(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C40H44Cl4N6O8S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0883063
 Compound Info 
N1,N4-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-ethyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C54H72Cl4N6O14S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0899490
 Compound Info 
N1,N4-bis(2-(2-(2-(2-(4-((S/R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
   Show/Hide
C52H68Cl4N6O14S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0921070
 Compound Info 
N1,N31-bis(2-(2-(2-(2-(4-(4-((E)-3-(diaminomethyl-eneamino)-2-methyl-3-oxoprop-1-enyl)-2,6-difluo-rophenoxy)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16,19,22,25,28-nonaoxahentriacontane-1,31-diamide
   Show/Hide
C29H39F2N5O9S
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0938227
 Compound Info 
N1,N4-bis(20-(4-(4-((E)-3-(diaminomethylene-amino)-2-methyl-3-oxoprop-1-enyl)-2,6-difluo-rophenoxy)phenylsulfonamido)-3,6,9,12,15,18-hexaoxaicosyl)-2,3-dihydroxysuccinamide
   Show/Hide
C66H92F4N10O24S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0941820
 Compound Info 
4-(3-(6-chloro-2-(diaminomethyleneamino)quinazolin-4-yl)phenyl)piperazine-1-carboximidamide
   Show/Hide
C20H22ClN9
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0958992
 Compound Info 
(2R,3R)-N1,N4-bis(20-(4-(4-((E)-3-(diaminomethyl-eneamino)-2-methyl-3-oxoprop-1-enyl)-2,6-difluo-rophenoxy)phenylsulfonamido)-3,6,9,12,15,18-hexaoxaicosyl)-2,3-dihydroxysuccinamide
   Show/Hide
C66H92F4N10O24S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0967206
 Compound Info 
N1,N31-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-4,7,10,13,16,19,22,25,28-nonaoxa-hentriacontane-1,31-diamide
   Show/Hide
C70H104Cl4N6O21S2
  1
1
IC50 = 1000 nM
 Bioactivity Info 
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CP0404357
 Compound Info 
US10272079, Compound 105
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C69H85Cl5N8O14S2
  1
1
IC50 = 1258.93 nM
 Bioactivity Info 
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CP0497758
 Compound Info 
US10272079, Compound 85
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C102H132Cl8N14O22S4
  1
1
IC50 = 1584.89 nM
 Bioactivity Info 
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CP0529543
 Compound Info 
US10272079, Compound 110
   Show/Hide
C70H88Cl5N11O14S2
  1
1
IC50 = 1584.89 nM
 Bioactivity Info 
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CP0903666
 Compound Info 
(S)-N,N'-(15-(1-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-10-oxo-3,6-dioxa-9,11-diazatetradecan-14-yl)-10,20-dioxo-15-(3-((2S,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)ureido)-3,6,24,27-tetraoxa-9,11,19,21-tetraazanonacosane-1,29-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
   Show/Hide
C86H120Cl6N14O21S3
  1
1
IC50 = 1584.89 nM
 Bioactivity Info 
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CP0913565
 Compound Info 
(S)-N,N'-(14-(1-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-14-(13-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-4-oxo-8,11-dioxa-3,5-diazatridecyl)-10,15-dioxo-3,6-dioxa-9,11,14,16-tetraazaoctacosan-28-ylcarbamoyl)-10,18-dioxo-3,6,22,25-tetraoxa-9,11,14,17,19-pentaazaheptacosane-1,27-diyl)bis(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C114H158Cl8N20O22S4
  1
1
IC50 = 1584.89 nM
 Bioactivity Info 
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CP0546592
 Compound Info 
US10272079, Compound 167
   Show/Hide
C86H120Cl6N14O21S3
  1
1
IC50 = 1584.89 nM
 Bioactivity Info 
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CP0573234
 Compound Info 
N-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethyl]-3-[2-[2-[[3-(6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl)phenyl]sulfonylamino]ethoxy]ethylamino]-2,3-dihydroxypropanamide
   Show/Hide
C43H52Cl4N6O9S2
  1
1
IC50 = 1584.89 nM
 Bioactivity Info 
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CP0374444
 Compound Info 
US10272079, Compound 76
   Show/Hide
C75H99Cl6N13O15S3
  1
1
IC50 = 2511.89 nM
 Bioactivity Info 
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CP0420504
 Compound Info 
US10272079, Compound 129
   Show/Hide
C79H103Cl6N11O16S3
  1
1
IC50 = 2511.89 nM
 Bioactivity Info 
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CP0406309
 Compound Info 
US10272079, Compound 38
   Show/Hide
C20H24N2O3S
  1
1
IC50 = 3162.28 nM
 Bioactivity Info 
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CP0434872
 Compound Info 
US10272079, Compound 80
   Show/Hide
C75H96Cl6N10O15S3
  1
1
IC50 = 3162.28 nM
 Bioactivity Info 
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CP0957148
 Compound Info 
4-[2-(1-piperidyl)indan-1-yl]oxybenzenesulfonamide
   Show/Hide
C20H24N2O3S
  1
1
IC50 = 3162.28 nM
 Bioactivity Info 
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CP0380550
 Compound Info 
US10272079, Compound 73
   Show/Hide
C81H102Cl6N16O15S3
  1
1
IC50 = 5011.87 nM
 Bioactivity Info 
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CP0389074
 Compound Info 
US10272079, Compound 91
   Show/Hide
C95H117Cl7N10O19S3
  1
1
IC50 = 5011.87 nM
 Bioactivity Info 
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CP0550394
 Compound Info 
N1,N4-bis(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)terephthalamide
   Show/Hide
C52H60Cl4N6O10S2
  2
1
IC50 = 6309.57 nM
 Bioactivity Info 
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2
IC50 = 10000 nM
 Bioactivity Info 
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CP0576727
 Compound Info 
N,N&#8242;-(1,1&#8242;-(1,4-phenylenebis(azanediyl))bis(1-oxo-5,8,11-trioxa-2-azatridecane-13,1-diyl))bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
   Show/Hide
C56H70Cl4N8O12S2
  1
1
IC50 = 6309.57 nM
 Bioactivity Info 
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CP0572270
 Compound Info 
US10272079, Compound 3
   Show/Hide
C22H26Cl2N2O6
  1
1
IC50 = 7943.28 nM
 Bioactivity Info 
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CP0374440
 Compound Info 
US10272079, Compound 62
   Show/Hide
C26H35Cl2N3O5S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0379944
 Compound Info 
US10272079, Compound 68
   Show/Hide
C58H78Cl4N8O12S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0380072
 Compound Info 
US10272079, Compound 112
   Show/Hide
C37H42Cl3N3O5S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0380073
 Compound Info 
US10272079, Compound 113
   Show/Hide
C89H107Cl7N10O15S3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0389173
 Compound Info 
US10272079, Compound 116
   Show/Hide
C52H72Cl2N8O12S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0396065
 Compound Info 
US10272079, Compound 166
   Show/Hide
C52H70Cl2F2N8O12S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0404354
 Compound Info 
US10272079, Compound 158
   Show/Hide
C81H107Cl6N11O19S3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0411215
 Compound Info 
US10272079, Compound 125
   Show/Hide
C52H77Cl2N3O7S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0415043
 Compound Info 
US10272079, Compound 004
   Show/Hide
C50H66Cl4N8O10S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0415048
 Compound Info 
US10272079, Compound 115
   Show/Hide
C52H74N8O12S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0415652
 Compound Info 
US10272079, Compound 87
   Show/Hide
C56H74Cl4N8O14S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0427529
 Compound Info 
US10272079, Compound 101
   Show/Hide
C60H76N6O12S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0431400
 Compound Info 
US10272079, Compound 83
   Show/Hide
C112H152Cl8N18O22S4
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0434866
 Compound Info 
US10272079, Compound 152
   Show/Hide
C54H66Cl4N8O12S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0434870
 Compound Info 
US10272079, Compound 92
   Show/Hide
C35H53Cl2N3O6S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0446364
 Compound Info 
US10272079, Compound 126
   Show/Hide
C60H84N10O10
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0451791
 Compound Info 
US10272079, Compound 165
   Show/Hide
C56H74Cl2F2N8O14S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0471224
 Compound Info 
US10272079, Compound 136
   Show/Hide
C52H72F2N8O12S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0477878
 Compound Info 
US10272079, Compound 94
   Show/Hide
C87H118Cl6N10O16S3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0497759
 Compound Info 
US10272079, Compound 93
   Show/Hide
C37H40Cl3N3O6S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0529373
 Compound Info 
US10272079, Compound 121
   Show/Hide
C85H125Cl4N11O15S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0559118
 Compound Info 
US10272079, Compound 111
   Show/Hide
C39H55Cl2N3O6S
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0848355
 Compound Info 
3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(26-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosyl)benzenesulfonamide dihydrochloride
   Show/Hide
C50H68Cl6N8O10S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0941818
 Compound Info 
4-((4'-chlorobiphenyl-4-yl)methylamino)-4-(1-(3-((R)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)-13-oxo-3,6,9-trioxa-12-azapentadecan-15-yl)-N1,N7-bis(2-(2-(2-(2-(3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)heptanediamide
   Show/Hide
C95H119Cl7N10O18S3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0445476
 Compound Info 
N1,N3-bis(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)-2,2-dimethylmalonamide
   Show/Hide
C49H62Cl4N6O10S2
  1
1
IC50 = 10000 nM
 Bioactivity Info 
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CP0466743
 Compound Info 
N,N&#8242;-(10-oxo-3,6,14,17-tetraoxa-9,11-diazanonadecane-1,19-diyl)bis(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
   Show/Hide
C45H56Cl4N6O9S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
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CP0557126
 Compound Info 
2-(N-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfamoylamino)ethylphosphonic Acid
   Show/Hide
C18H22Cl2N3O5PS
  1
1
IC50 = 10000 nM
 Bioactivity Info 
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CP0557127
 Compound Info 
(E)-3-(4-(4-(3-(diaminomethyleneamino)-2-methyl-3-oxoprop-1-enyl)-2,6-difluorophenoxy)phenylsulfonamido)propylphosphonic Acid
   Show/Hide
C20H23F2N4O7PS
  1
1
IC50 = 10000 nM
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CP0572956
 Compound Info 
N,N&#8242;-(10-oxo-3,6,14,17-tetraoxa-9,11-diazanonadecane-1,19-diyl)bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C45H56Cl4N6O9S2
  1
1
IC50 > 10000 nM
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CP0847224
 Compound Info 
N1,N4-bis(2-(2-(2-(2-(3-((R/S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)-2,3-dihydroxysuccinamide
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C52H68Cl4N6O10
  1
1
IC50 > 10000 nM
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CP0847225
 Compound Info 
2-(6-chloro-4-(3-(4-((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl)piperazin-1-yl)phenyl)quinazolin-2-yl)guanidine
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C25H30ClN7O6
  1
1
IC50 = 10000 nM
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CP0883061
 Compound Info 
3,3'-(2,2'-(2,2'-(2,2'-oxybis(ethane-2,1-diyl)bis(oxy))bis(ethane-2,1-diyl))bis(6,8-dichloro-1,2,3,4-tetrahydroisoquinoline-4,2-diyl))dianiline
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C38H42Cl4N4O3
  1
1
IC50 > 10000 nM
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CP0883062
 Compound Info 
(E)-4-((4-(4-(3-(diaminomethyleneamino)-2-methyl-3-oxoprop-1-eny1)-2,6-difluorophenoxy)phenylsulfonamido)methyl)benzylphosphonic acid
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C25H25F2N4O7PS
  1
1
IC50 = 10000 nM
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CP0897723
 Compound Info 
N1,N2-bis(2-(2-(2-(4-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethyl)oxalamide
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C46H56Cl4N6O10S2
  1
1
IC50 > 10000 nM
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CP0899489
 Compound Info 
N1,N4-bis(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethyl)-2,3-dihydroxysuccinamide
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C44H52Cl4N6O10S2
  1
1
IC50 = 10000 nM
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CP0941819
 Compound Info 
N,N'-(1,1'-(1,4-phenylenebis(azanediyl))bis(1-oxo-5,8,11-trioxa-2-azatridecane-13,1-diyl))bis(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzenesulfonamide)
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C56H70Cl4N8O12S2
  1
1
IC50 = 10000 nM
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CP0961127
 Compound Info 
N1,N3-bis(2-(2-(2-(2-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylsulfonamido)ethoxy)ethoxy)ethoxy)ethyl)benzene-1,3-disulfonamide
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C54H68Cl4N6O14S4
  1
1
IC50 = 10000 nM
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CP0962784
 Compound Info 
2-(N-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfamoylamino)ethylphosphonic acid
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C18H22Cl2N3O5PS
  1
1
IC50 = 10000 nM
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CP0967203
 Compound Info 
N1,N4-bis(1-(3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenylamino)-1-oxo-5,8,11-trioxa-2-azatridecan-13-yl)-2,3-dihydroxysuccinamide
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C54H70Cl4N8O12
  1
1
IC50 > 10000 nM
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CP0967204
 Compound Info 
3-(4-(3-(6-chloro-2-(diaminomethyleneamino)quinazolin-4-yl)phenyl)piperazin-1-yl)propanoic acid
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C22H24ClN7O2
  1
1
IC50 = 10000 nM
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CP0559117
 Compound Info 
US10272079, Compound 114
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C95H119Cl7N10O18S3
  1
1
IC50 > 10000 nM
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CP0880614
 Compound Info 
1-[2-[2-[2-[[4-[(1S,2S)-6-chloro-4-fluoro-2-[(3R)-3-hydroxypyrrolidin-1-yl]indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[4-[(1S,2S)-4,6-dichloro-2-[(3R)-3-hydroxypyrrolidin-1-yl]indan-1-yl]oxyphenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea
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C56H74Cl3FN8O14S2
  1
1
IC50 > 10000 nM
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CP0902826
 Compound Info 
1-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[3-[(4R)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea Dihydrochloride
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C50H68Cl6N8O10S2
  1
1
IC50 > 10000 nM
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