| Compound ID |
Compound Name |
Compound Formula |
|
CP0040184
|
1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-1,3-benzodiazol-2-amine
Show/Hide
|
C28H31FN4O
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0470567
|
CHEBI:3720
Show/Hide
|
C23H29ClFN3O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0870344
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)cyclohexanesulfonamide dihydrochloride
Show/Hide
|
C28H45Cl2N3O3S
|
1
|
| 1 |
IC50 = 18.2 nM
|
|
|
|
CP0905694
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)methanesulfonamide dihydrochloride
Show/Hide
|
C23H37Cl2N3O3S
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0862615
|
6-butyl-8-(1-(3-(propylsulfonyl)propyl)piperidin-4-yloxy)quinoline dihydrochloride
Show/Hide
|
C24H38Cl2N2O3S
|
1
|
| 1 |
IC50 = 28.84 nM
|
|
|
|
CP0878528
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)-2-methylpropane-1-sulfonamide dihydrochloride
Show/Hide
|
C26H43Cl2N3O3S
|
1
|
| 1 |
IC50 = 43.65 nM
|
|
|
|
CP0170580
|
5-(2,3-difluorophenyl)-N-[[1-(2-methoxyethyl)piperidin-4-yl]methyl]-1H-indazole-3-carboxamide
Show/Hide
|
C23H26F2N4O2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0472007
|
[9-[[2-(2-methoxyphenoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyridin-4-ylmethanone
Show/Hide
|
C29H33N3O3
|
1
|
| 1 |
IC50 = 45.71 nM
|
|
|
|
CP0565087
|
4-[[2-[[1-[2-(4-cyanophenyl)ethyl]piperidin-4-yl]amino]benzimidazol-1-yl]methyl]-2-fluorobenzonitrile
Show/Hide
|
C29H27FN6
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0565373
|
4-[2-[4-[[1-[(4-cyanophenyl)methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]benzonitrile
Show/Hide
|
C29H28N6
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0056747
|
4-[(4-Chlorophenyl)methyl]-2-({(2R)-1-[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)-1(2H)-phthalazinone
Show/Hide
|
C39H49ClN4O2
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0946944
|
N-(3-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)propyl)ethanesulfonamide dihydrochloride
Show/Hide
|
C23H37Cl2N3O3S
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0438777
|
[9-[[2-(2-methoxyphenoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyrimidin-4-ylmethanone
Show/Hide
|
C28H32N4O3
|
1
|
| 1 |
IC50 = 70.79 nM
|
|
|
|
CP0862516
|
N-(2-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)ethyl)ethanesulfonamide dihydrochloride
Show/Hide
|
C22H35Cl2N3O3S
|
1
|
| 1 |
IC50 = 75.86 nM
|
|
|
|
CP0862616
|
6-butyl-8-(1-(3-(ethylsulfonyl)propyl)piperidin-4-yloxy)quinoline dihydrochloride
Show/Hide
|
C23H36Cl2N2O3S
|
1
|
| 1 |
IC50 = 75.86 nM
|
|
|
|
CP0702373
|
N-(4-{4-[(6-Butyl-8-quinolinyl)oxy]-1-piperidinyl}butyl)ethanesulfonamide dihydrochloride
Show/Hide
|
C24H39Cl2N3O3S
|
1
|
| 1 |
IC50 = 77.62 nM
|
|
|
|
CP0401476
|
(4-chlorophenyl)-[9-[(2-phenoxyphenyl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
|
C29H31ClN2O2
|
1
|
| 1 |
IC50 = 83.18 nM
|
|
|
|
CP0397183
|
(4-chlorophenyl)-[9-[[2-(2-methoxyphenoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
|
C30H33ClN2O3
|
1
|
| 1 |
IC50 = 87.1 nM
|
|
|
|
CP0852619
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)propane-1-sulfonamide dihydrochloride
Show/Hide
|
C25H41Cl2N3O3S
|
1
|
| 1 |
IC50 = 87.1 nM
|
|
|
|
CP0527614
|
4-[2-[4-(1H-benzimidazol-2-ylamino)piperidin-1-yl]ethyl]benzonitrile
Show/Hide
|
C21H23N5
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0946943
|
6-butyl-8-(1-(3-(isopropylsulfonyl)propyl)piperidin-4-yloxy)quinoline dihydrochloride
Show/Hide
|
C24H38Cl2N2O3S
|
1
|
| 1 |
IC50 = 91.2 nM
|
|
|
|
CP0493726
|
4-[4-(6-butylquinolin-8-yl)oxypiperidin-1-yl]-N-propylbutane-1-sulfonamide
Show/Hide
|
C25H39N3O3S
|
1
|
| 1 |
IC50 = 95.5 nM
|
|
|
|
CP0294233
|
4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0435813
|
4-phenyl-9-(2-phenylethyl)-2-(phenylmethoxymethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C30H34N2O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0444498
|
9-[2-(4-fluorophenyl)ethyl]-2-methyl-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H27FN2O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0482313
|
2-methyl-9-(2-phenylethyl)-4-pyrazin-2-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C21H26N4O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0533222
|
2,2-dimethyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C24H30N2O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0527615
|
4-[2-[4-[[1-[(4-methylsulfonylphenyl)methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]benzonitrile
Show/Hide
|
C29H31N5O2S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0002229
|
(Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-phenyl)-ethyl]-methylamino}-ethoxy)-phenyl]-methanesulfonamide
Show/Hide
|
C19H27N3O5S2
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0007317
|
(+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol
Show/Hide
|
C22H31NO
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0905695
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)propane-2-sulfonamide dihydrochloride
Show/Hide
|
C25H41Cl2N3O3S
|
1
|
| 1 |
IC50 = 128.82 nM
|
|
|
|
CP0808299
|
3-((3,4-Dichlorophenoxy)(naphthalen-2-yl)methyl)azetidine hydrochloride
Show/Hide
|
C20H18Cl3NO
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0435808
|
methyl 2-[3-oxo-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-2-yl]acetate
Show/Hide
|
C25H30N2O4
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0036382
|
CAS_52-53-9
Show/Hide
|
C27H38N2O4
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0471992
|
[9-[[2-(2-methoxyphenoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-(1-oxidopyridin-1-ium-4-yl)methanone
Show/Hide
|
C29H33N3O4
|
1
|
| 1 |
IC50 = 218.78 nM
|
|
|
|
CP0388413
|
[9-[(2-phenoxyphenyl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyrimidin-4-ylmethanone
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 = 229.09 nM
|
|
|
|
CP0951179
|
N-(4-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)butyl)-N-methylethanesulfonamide dihydrochloride
Show/Hide
|
C25H41Cl2N3O3S
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0526445
|
N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-4-[2-(6-methoxyquinolin-4-yl)ethyl]cyclohexan-1-amine
Show/Hide
|
C27H32N2O3
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0947001
|
N-tert-butyl-3-(4-(6-butylquinolin-8-yloxy)piperidin-1-yl)propane-1-sulfonamide dihydrochloride
Show/Hide
|
C25H41Cl2N3O3S
|
1
|
| 1 |
IC50 = 281.84 nM
|
|
|
|
CP0444838
|
(2S)-2-methyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0853877
|
6-butyl-8-(1-(4-(tert-butylsulfonyl)butyl)piperidin-4-yloxy)quinoline dihydrochloride
Show/Hide
|
C26H42Cl2N2O3S
|
1
|
| 1 |
IC50 = 302 nM
|
|
|
|
CP0368391
|
4-[[1-(5-cyanopyridin-2-yl)piperidin-4-yl]amino]-6-(pyridin-2-ylamino)pyridine-3-carboxamide
Show/Hide
|
C22H22N8O
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0391894
|
1-[5-[4-(4-chlorophenyl)phenoxy]pentyl]-4-pyridin-4-ylpiperazin-2-one
Show/Hide
|
C26H28ClN3O2
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0110465
|
6-chloro-N-(piperidin-4-ylmethyl)-3-[3-(trifluoromethoxy)phenyl]triazolo[4,5-b]pyridin-5-amine
Show/Hide
|
C18H18ClF3N6O
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0473010
|
N-[2-[(2R)-2-[[4-[(4-chlorophenyl)methyl]-1-oxophthalazin-2-yl]methyl]pyrrolidin-1-yl]ethyl]-4-methoxybutanamide;dihydrochloride
Show/Hide
|
C27H35Cl3N4O3
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0435812
|
2-methyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0435824
|
2-ethyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C24H30N2O2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0517732
|
6-[[[4-[2-(6-methoxyquinolin-4-yl)ethyl]cyclohexyl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0547242
|
N'-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]-N-[2-(4-methoxyphenyl)ethyl]propane-1,3-diamine
Show/Hide
|
C26H29FN4O
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0356157
|
1-(4-chlorophenyl)-2-[3-(4-fluorophenoxy)propyl]guanidine
Show/Hide
|
C16H17ClFN3O
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0439221
|
[9-[(3-phenoxyphenyl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyridin-4-ylmethanone
Show/Hide
|
C28H31N3O2
|
1
|
| 1 |
IC50 = 446.68 nM
|
|
|
|
CP0404568
|
6-butyl-8-[1-(3-tert-butylsulfonylpropyl)piperidin-4-yl]oxyquinoline
Show/Hide
|
C25H38N2O3S
|
1
|
| 1 |
IC50 = 467.74 nM
|
|
|
|
CP0435811
|
2-methyl-9-(2-phenylethyl)-4-[5-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H26F3N3O2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0915882
|
(R)-4-(3,5-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0190183
|
4-(3-methylanilino)-2-[[(3R)-pyrrolidin-3-yl]amino]pyrimidine-5-carboxamide
Show/Hide
|
C16H20N6O
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0476468
|
9-[2-(3-fluorophenyl)ethyl]-2-methyl-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H27FN2O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0482315
|
3-[2-(2-methyl-3-oxo-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)ethyl]benzonitrile
Show/Hide
|
C24H27N3O2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0534442
|
1-[3-(3,5-dimethylphenyl)-5-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]pyridin-4-yl]piperidin-4-amine
Show/Hide
|
C26H26F3N5
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0418633
|
(4-chlorophenyl)-[9-[(3-phenoxyphenyl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
|
C29H31ClN2O2
|
1
|
| 1 |
IC50 = 602.56 nM
|
|
|
|
CP0460793
|
N-tert-butyl-2-[4-(6-butylquinolin-8-yl)oxypiperidin-1-yl]ethanesulfonamide
Show/Hide
|
C24H37N3O3S
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0096458
|
2-[(3S)-3-aminopiperidin-1-yl]-4-[3-(trifluoromethyl)anilino]pyrimidine-5-carboxamide
Show/Hide
|
C17H19F3N6O
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0558561
|
1-(2-aminopyridin-4-yl)-3-[5-[4-[(E)-ethoxyiminomethyl]phenoxy]-3-methylpentyl]imidazolidin-2-one
Show/Hide
|
C23H31N5O3
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0518458
|
9-[2-(2-fluorophenyl)ethyl]-2-methyl-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H27FN2O2
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0543354
|
4-(4-aminopiperidin-1-yl)-N,5-bis(3,5-dimethylphenyl)pyridine-3-carboxamide
Show/Hide
|
C27H32N4O
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0517731
|
N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-1-[2-(6-methoxyquinolin-4-yl)ethyl]piperidin-4-amine
Show/Hide
|
C26H31N3O3
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0711358
|
3-(Naphthalen-2-yl(phenoxy)methyl)azetidine hydrochloride
Show/Hide
|
C20H20ClNO
|
1
|
| 1 |
IC50 = 830 nM
|
|
|
|
CP0562234
|
N-(oxan-4-ylmethyl)-5-(5-propan-2-yloxypyridin-3-yl)-1H-indazole-3-carboxamide
Show/Hide
|
C22H26N4O3
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0564269
|
N-[4-(4-aminopiperidin-1-yl)-5-(3,5-dichlorophenyl)pyridin-3-yl]benzamide
Show/Hide
|
C23H22Cl2N4O
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0383195
|
N-(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-ylmethyl)-4-[2-(6-methoxyquinolin-4-yl)ethyl]cyclohexan-1-amine
Show/Hide
|
C26H31N3O3
|
1
|
| 1 |
IC50 = 940 nM
|
|
|
|
CP0527616
|
4-[2-[4-[[1-[[6-(trifluoromethyl)pyridin-3-yl]methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]benzonitrile
Show/Hide
|
C28H27F3N6
|
1
|
| 1 |
IC50 = 970 nM
|
|
|
|
CP0877734
|
3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride
Show/Hide
|
C17H22ClNO
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0223903
|
4-(3-methylanilino)-2-[[(2S)-pyrrolidin-2-yl]methylamino]pyrimidine-5-carboxamide
Show/Hide
|
C17H22N6O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0010656
|
3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H27FN4O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0465007
|
8-[4-[3-[4-[3-(azepan-1-yl)propoxy]phenyl]propyl]piperazin-1-yl]quinoline
Show/Hide
|
C31H42N4O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0558577
|
N-[(3,4-dichlorophenyl)methyl]-1-[2-(6-methoxyquinolin-4-yl)ethyl]piperidin-4-amine
Show/Hide
|
C24H27Cl2N3O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0435815
|
4-(3-methoxyphenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C24H30N2O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0518441
|
4-(2-chlorophenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H27ClN2O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0534443
|
1-[3-(3,5-dimethylphenyl)-5-(6-methyl-1H-benzimidazol-2-yl)pyridin-4-yl]piperidin-4-amine
Show/Hide
|
C26H29N5
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0482314
|
4-(5-fluoropyridin-3-yl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H26FN3O2
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0533224
|
2-(hydroxymethyl)-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0435809
|
4-phenyl-9-(2-phenylethyl)-2-propan-2-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C25H32N2O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0444474
|
12-phenyl-8-(2-phenylethyl)-4-oxa-8,12-diazadispiro[2.1.55.33]tridecan-13-one
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0444844
|
4-(3-fluoropyridin-2-yl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H26FN3O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0518437
|
4-(2-fluorophenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H27FN2O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0518439
|
(2R)-2-methyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0018952
|
6-[[[2-[2-(6-methoxyquinolin-4-yl)ethyl]-1,3-dioxan-5-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]thiazin-3-one
Show/Hide
|
C24H26N4O4S
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0054655
|
3-[2-(4-chloro-3-fluorophenyl)-2-(2-fluorophenoxy)ethyl]azetidine
Show/Hide
|
C17H16ClF2NO
|
1
|
| 1 |
IC50 = 1410 nM
|
|
|
|
CP0472951
|
3-benzyl-N-[[5-(2-methylpropyl)-1-phenylpyrazol-3-yl]methyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
Show/Hide
|
C27H32N4O
|
1
|
| 1 |
IC50 = 1430 nM
|
|
|
|
CP0054654
|
3-[2-(4-chloro-3-fluorophenyl)-2-(3-fluorophenoxy)ethyl]azetidine
Show/Hide
|
C17H16ClF2NO
|
1
|
| 1 |
IC50 = 1460 nM
|
|
|
|
CP0885484
|
3-((4-Chloro-3-fluorophenyl)(phenoxy)methyl)azetidine hydrochloride
Show/Hide
|
C16H16Cl2FNO
|
1
|
| 1 |
IC50 = 1560 nM
|
|
|
|
CP0748832
|
(R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0069956
|
4-(3-methylanilino)-2-[[(3S)-piperidin-3-yl]amino]pyrimidine-5-carboxamide
Show/Hide
|
C17H22N6O
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0287539
|
2-(azetidin-3-ylamino)-4-(3-methylanilino)pyrimidine-5-carboxamide
Show/Hide
|
C15H18N6O
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0002227
|
SOLIFENACIN
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0010653
|
2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrrolidin-3-yl}-2,2-diphenyl-acetamide (Darifenacin)
Show/Hide
|
C28H30N2O2
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0450309
|
8-[4-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]butyl]piperazin-1-yl]quinoline
Show/Hide
|
C32H44N4O
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0419804
|
N-[[1-(4-fluorophenyl)-5-(2-methylpropyl)pyrazol-3-yl]methyl]quinoline-8-sulfonamide
Show/Hide
|
C23H23FN4O2S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0915497
|
6-butyl-8-(1-(2-(ethylsulfonyl)ethyl)piperidin-4-yloxy)quinoline dihydrochloride
Show/Hide
|
C22H34Cl2N2O3S
|
1
|
| 1 |
IC50 = 1659.59 nM
|
|
|
|
CP0487473
|
1-[3-[(3,5-dimethylphenoxy)methyl]-5-(3,5-dimethylphenyl)pyridin-4-yl]piperidin-4-amine
Show/Hide
|
C27H33N3O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0534440
|
N-[4-(4-aminopiperidin-1-yl)-5-(3,5-dimethylphenyl)pyridin-3-yl]-3,5-dimethylbenzamide
Show/Hide
|
C27H32N4O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0540379
|
1-[3-(6-chloro-1H-benzimidazol-2-yl)-5-(3,5-dimethylphenyl)pyridin-4-yl]piperidin-4-amine
Show/Hide
|
C25H26ClN5
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0558786
|
4-(4-aminopiperidin-1-yl)-5-(3,5-dimethylphenyl)-N-[(3,5-dimethylphenyl)methyl]pyridin-3-amine
Show/Hide
|
C27H34N4
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0561761
|
1-[4-[6-(4-chlorophenyl)-3,4-dihydro-2H-chromen-2-yl]butyl]-3-pyridin-4-ylimidazolidin-2-one
Show/Hide
|
C27H28ClN3O2
|
1
|
| 1 |
IC50 = 1750 nM
|
|
|
|
CP0554552
|
5-(2,3-difluorophenyl)-N-(oxan-4-yl)-1H-indazole-3-carboxamide
Show/Hide
|
C19H17F2N3O2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0250545
|
N-(azetidin-3-ylmethyl)-N-[(2,3-dichlorophenyl)methyl]aniline;2,2,2-trifluoroacetic acid
Show/Hide
|
C19H19Cl2F3N2O2
|
1
|
| 1 |
IC50 = 1880 nM
|
|
|
|
CP0075084
|
1-cyclopropyl-N-((6-(4-fluoro-2-methoxyphenyl)pyrazin-2-yl)methyl)methanamine
Show/Hide
|
C16H18FN3O
|
1
|
| 1 |
IC50 = 1890 nM
|
|
|
|
CP0199373
|
N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]cyclopentanamine
Show/Hide
|
C18H21FN2O
|
1
|
| 1 |
IC50 = 1890 nM
|
|
|
|
CP0469703
|
N-(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-ylmethyl)-1-[2-(6-methoxyquinolin-4-yl)ethyl]piperidin-4-amine
Show/Hide
|
C25H30N4O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0482317
|
2-(methoxymethyl)-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C24H30N2O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0547461
|
(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((5-methoxypyridin-2-yl)methyl)piperazin-1-yl)prop-2-en-1-one
Show/Hide
|
C23H26ClN7O2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0487472
|
N-[4-(4-aminopiperidin-1-yl)-5-(3,5-dichlorophenyl)pyridin-3-yl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C24H22Cl2N6O
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0397182
|
[9-[[2-(2-methylpropoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyridin-4-ylmethanone
Show/Hide
|
C26H35N3O2
|
1
|
| 1 |
IC50 = 1905.46 nM
|
|
|
|
CP0430796
|
[9-[[3-(2-methoxyphenoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyrimidin-4-ylmethanone
Show/Hide
|
C28H32N4O3
|
1
|
| 1 |
IC50 = 1905.46 nM
|
|
|
|
CP0372715
|
[9-[(3-phenoxyphenyl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyrimidin-4-ylmethanone
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 = 1949.84 nM
|
|
|
|
CP0178475
|
2-(2-aminoethylamino)-4-(m-tolylamino)pyrimidine-5-carboxamide
Show/Hide
|
C14H18N6O
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0426943
|
N-[3-chloro-4-[5-(4-piperidin-1-ylbutylamino)-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
Show/Hide
|
C24H27ClFN5O2
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0029082
|
N-[(4-chlorophenyl)methyl]-2-[2-(6-methoxyquinolin-4-yl)ethyl]-1,3-dioxan-5-amine
Show/Hide
|
C23H25ClN2O3
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0435818
|
2-methyl-4-phenyl-9-(2-pyridin-2-ylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H27N3O2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0573805
|
1-[3-(4,6-dimethyl-1H-benzimidazol-2-yl)-5-(3,5-dimethylphenyl)pyridin-4-yl]piperidin-4-amine
Show/Hide
|
C27H31N5
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0451063
|
(4R,4aR,8aS)-8a-(2,4-difluorophenyl)-4-methyl-6-(3-methyl-1,2-oxazol-5-yl)-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
|
C18H19F2N3O2S
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0569456
|
(4S,4aR,8aS)-8a-(2,4-difluorophenyl)-4-(fluoromethyl)-6-(3-methyl-1,2-oxazol-5-yl)-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
|
C18H18F3N3O2S
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0422581
|
5-(2,3-difluorophenyl)-N-(1,1-dioxothian-4-yl)-1H-indazole-3-carboxamide
Show/Hide
|
C19H17F2N3O3S
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0432152
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
|
C24H30N4O2S
|
1
|
| 1 |
IC50 = 2110 nM
|
|
|
|
CP0456354
|
N-[[3-(4-fluoro-2-methoxyphenyl)phenyl]methyl]cyclopentanamine
Show/Hide
|
C19H22FNO
|
1
|
| 1 |
IC50 = 2150 nM
|
|
|
|
CP0520915
|
N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]cyclohexanamine
Show/Hide
|
C19H23FN2O
|
1
|
| 1 |
IC50 = 2180 nM
|
|
|
|
CP0912528
|
6-(8-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)octylamino)-5,6,7,8-tetrahydroquinolin-2(1H)-one
Show/Hide
|
C30H39ClN4O
|
1
|
| 1 |
IC50 = 2191 nM
|
|
|
|
CP0885339
|
3-((3,4-Dichlorophenyl)(propoxy)methyl)azetidine hydrochloride
Show/Hide
|
C13H18Cl3NO
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0559166
|
2-[4-(4-aminopiperidin-1-yl)-5-(3,5-dimethylphenyl)pyridin-3-yl]-3H-benzimidazole-5-carbonitrile
Show/Hide
|
C26H26N6
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0416745
|
N-[(3,4-dichlorophenyl)methyl]-4-[2-(6-methoxyquinolin-4-yl)ethyl]cyclohexan-1-amine
Show/Hide
|
C25H28Cl2N2O
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0390889
|
[9-[[2-(2-methylprop-2-enoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyridin-4-ylmethanone
Show/Hide
|
C26H33N3O2
|
1
|
| 1 |
IC50 = 2344.23 nM
|
|
|
|
CP0835358
|
6-(2-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)ethylamino)-5,6,7,8-tetrahydroquinolin-2(1H)-one
Show/Hide
|
C24H27ClN4O
|
1
|
| 1 |
IC50 = 2408 nM
|
|
|
|
CP0017736
|
6-[[[2-[2-(6-methoxyquinolin-4-yl)ethyl]-1,3-dioxan-5-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C24H26N4O5
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0189449
|
4-(3-methylanilino)-2-[[(3R)-piperidin-3-yl]amino]pyrimidine-5-carboxamide
Show/Hide
|
C17H22N6O
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0190184
|
4-(3-methylanilino)-2-[[(2R)-pyrrolidin-2-yl]methylamino]pyrimidine-5-carboxamide
Show/Hide
|
C17H22N6O
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0226765
|
4-(3-methylanilino)-2-(piperidin-2-ylmethylamino)pyrimidine-5-carboxamide
Show/Hide
|
C18H24N6O
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0313635
|
4-(3-methylanilino)-2-[[(3S)-pyrrolidin-3-yl]amino]pyrimidine-5-carboxamide
Show/Hide
|
C16H20N6O
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0450305
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-butylquinolin-2-yl]propanoic acid
Show/Hide
|
C37H52N4O3
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0184098
|
2-(1-adamantyl)-1-(4-iodophenyl)guanidine
Show/Hide
|
C17H22IN3
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0472950
|
3-(3,3-dimethylbutyl)-N-[[5-(2-methylpropyl)-1-phenylpyrazol-3-yl]methyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
Show/Hide
|
C26H38N4O
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0952332
|
6-(9-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)nonylamino)-5,6,7,8-tetrahydroquinolin-2(1H)-one
Show/Hide
|
C31H41ClN4O
|
1
|
| 1 |
IC50 = 2755 nM
|
|
|
|
CP0967562
|
6-(10-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)decylamino)-5,6,7,8-tetrahydroquinolin-2(1H)-one
Show/Hide
|
C32H43ClN4O
|
1
|
| 1 |
IC50 = 2768 nM
|
|
|
|
CP0540380
|
1-[3-(1H-benzimidazol-2-yl)-5-(3,5-dimethylphenyl)pyridin-4-yl]piperidin-4-amine
Show/Hide
|
C25H27N5
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0550627
|
N-[[3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]-5-(2-methylpropyl)-1-phenylpyrazole-3-carboxamide
Show/Hide
|
C26H38N4O
|
1
|
| 1 |
IC50 = 3130 nM
|
|
|
|
CP0189447
|
2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-(3-methylanilino)pyrimidine-5-carboxamide
Show/Hide
|
C18H24N6O
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0303918
|
2-[[(1R,2S)-2-amino-4,4-difluorocyclohexyl]amino]-4-(3-methylanilino)pyrimidine-5-carboxamide
Show/Hide
|
C18H22F2N6O
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0069651
|
7-methoxy-N-(piperidin-4-ylmethyl)-3-[3-(trifluoromethoxy)phenyl]triazolo[4,5-b]pyridin-5-amine
Show/Hide
|
C19H21F3N6O2
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0713718
|
N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine disulfate
Show/Hide
|
C20H24F3N5O5S
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0439960
|
[5-[3-(4-methylphenyl)-5-methylsulfonylphenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C18H18N2O4S3
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0405003
|
3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-2-[[5-(trifluoromethyl)pyridin-2-yl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C24H17F6N3O3
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0435805
|
2-methyl-9-(2-phenylethyl)-4-[4-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H26F3N3O2
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0401259
|
(5-aminopyridin-2-yl)-[9-[(2-ethyl-2-propyl-3H-1-benzofuran-4-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
|
C29H40N4O2
|
1
|
| 1 |
IC50 = 3467.37 nM
|
|
|
|
CP0301939
|
7-methoxy-3-oxo-2-(2-pyridin-2-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C25H22F3N3O4
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0487474
|
1-[3-(3,5-dimethylphenyl)-5-(6-fluoro-1H-benzimidazol-2-yl)pyridin-4-yl]piperidin-4-amine
Show/Hide
|
C25H26FN5
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0545856
|
6-[[[1-[2-(6-methoxyquinolin-4-yl)ethyl]piperidin-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0435810
|
2-methyl-9-(2-phenylethyl)-4-[2-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H26F3N3O2
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0498978
|
N-[[2-(4-fluoro-2-methoxyphenyl)pyridin-4-yl]methyl]cyclopentanamine
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C18H21FN2O
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1
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| 1 |
IC50 = 3850 nM
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CP0896091
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4-(4-chlorobenzoyl)-1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
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C28H34ClN3O5
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1
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| 1 |
IC50 = 3981.07 nM
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CP0201292
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2-[[(3R,4R)-3-aminooxan-4-yl]amino]-4-(3-methylanilino)pyrimidine-5-carboxamide
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C17H22N6O2
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1
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| 1 |
IC50 = 3981.07 nM
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CP0311031
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2-[[(3S,4R)-4-aminooxolan-3-yl]amino]-4-(3-methylanilino)pyrimidine-5-carboxamide
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C16H20N6O2
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1
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| 1 |
IC50 = 3981.07 nM
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CP0389757
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N-[3-chloro-4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
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C23H25ClFN5O2
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1
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| 1 |
IC50 = 3981.07 nM
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CP0414356
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N-[3-ethyl-4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
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C25H30FN5O2
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1
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| 1 |
IC50 = 3981.07 nM
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CP0489264
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2-fluoro-N-[3-methyl-4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
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C24H28FN5O2
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1
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| 1 |
IC50 = 3981.07 nM
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CP0007277
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Aloxi
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C19H24N2O
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1
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| 1 |
IC50 = 3981.07 nM
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CP0562233
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5-(2,3-difluorophenyl)-N-(oxan-4-ylmethyl)-1H-indazole-3-carboxamide
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C20H19F2N3O2
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1
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| 1 |
IC50 = 4100 nM
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CP0570592
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4-[[2-[[1-[2-(4-cyanophenyl)ethyl]piperidin-4-yl]amino]benzimidazol-1-yl]methyl]benzoic acid
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C29H29N5O2
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1
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| 1 |
IC50 = 4160 nM
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CP0418591
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(3-aminopyridin-2-yl)-[9-[(2,2-dimethyl-3H-1-benzofuran-7-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
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C26H34N4O2
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1
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| 1 |
IC50 = 4168.69 nM
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CP0392063
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2-(2-methyl-1-pyridin-2-ylpropan-2-yl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
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C26H24F3N3O3
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1
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| 1 |
IC50 = 4300 nM
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CP0944975
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5-(2,3-Difluorophenyl)-N-((tetrahydrofuran-3-yl)methyl)-1H-indazole-3-carboxamide
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C19H17F2N3O2
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1
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| 1 |
IC50 = 4300 nM
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CP0409004
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N-[[5-(2-methylpropyl)-1-phenylpyrazol-3-yl]methyl]quinoline-8-sulfonamide
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C23H24N4O2S
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1
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| 1 |
IC50 = 4670 nM
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CP0090151
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N-cyclopropyl-N-[(3,4-dichlorophenyl)methyl]azetidin-3-amine
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C13H16Cl2N2
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1
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| 1 |
IC50 = 4710 nM
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CP0232239
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2-[(4aR,6S,8aR)-2-amino-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-8a-yl]-N-(6-methoxypyridin-2-yl)-1,3-thiazole-5-carboxamide
Show/Hide
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C18H21N5O3S2
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1
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| 1 |
IC50 = 4800 nM
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CP0032213
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N-[(3,4-dichlorophenyl)methyl]-2-[2-(6-methoxyquinolin-4-yl)ethyl]-1,3-dioxan-5-amine
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C23H24Cl2N2O3
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1
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| 1 |
IC50 = 4800 nM
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CP0157774
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4-[[1-(5-cyanopyridin-2-yl)piperidin-4-yl]amino]-6-[(5-methylpyrazin-2-yl)amino]pyridine-3-carboxamide
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C22H23N9O
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1
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| 1 |
IC50 = 4800 nM
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CP0373959
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[9-[[2-(2-methylpropoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyrimidin-4-ylmethanone
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C25H34N4O2
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1
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| 1 |
IC50 = 4897.79 nM
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CP0114257
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3-oxo-2-(2-pyridin-2-yloxyethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
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C24H20F3N3O4
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1
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| 1 |
IC50 = 4900 nM
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CP0548117
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N-[4-(4-aminopiperidin-1-yl)-5-(3,5-dichlorophenyl)pyridin-3-yl]-2,5-dimethylpyrazole-3-carboxamide
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C22H24Cl2N6O
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1
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| 1 |
IC50 = 4900 nM
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CP0578857
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1-[3-(3-chloro-5-fluorophenyl)-5-(6-fluoro-1H-benzimidazol-2-yl)pyridin-4-yl]piperidin-4-amine
Show/Hide
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C23H20ClF2N5
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1
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| 1 |
IC50 = 4900 nM
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CP0126140
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2-fluoro-N-[3-methoxy-4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
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C24H28FN5O3
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1
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| 1 |
IC50 = 5011.87 nM
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CP0519796
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2-fluoro-N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]-3-(trifluoromethyl)phenyl]benzamide
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C24H25F4N5O2
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1
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| 1 |
IC50 = 5011.87 nM
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CP0573108
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5-[4-(difluoromethoxy)phenyl]-3-[2-(2,4-difluorophenyl)-2-oxoethyl]-5-methylimidazolidine-2,4-dione
Show/Hide
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C19H14F4N2O4
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1
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| 1 |
IC50 = 5011.87 nM
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CP0213835
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7-(5-methylthiophen-2-yl)-N-[[(3S)-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
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C18H21N5S
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1
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| 1 |
IC50 = 5011.87 nM
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CP0381632
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3-oxo-2-(2-pyridin-4-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C24H20F3N3O3
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1
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| 1 |
IC50 = 5100 nM
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CP0032212
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N-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-2-[2-(6-methoxyquinolin-4-yl)ethyl]-1,3-dioxan-5-amine
Show/Hide
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C25H28N2O5
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1
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| 1 |
IC50 = 5100 nM
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CP0401281
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pyridin-4-yl-[9-[[2-(1,1,2,2-tetrafluoroethoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
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C24H27F4N3O2
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1
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| 1 |
IC50 = 5128.61 nM
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CP0486684
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N-benzyl-5-(4-fluoro-2-methoxyphenyl)pyridin-3-amine
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C19H17FN2O
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1
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| 1 |
IC50 = 5200 nM
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CP0223061
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1-[4-[4-[(5-chloro-4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]-3-methylpyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
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C22H23ClN8O
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1
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| 1 |
IC50 = 5200 nM
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CP0307982
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1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3-ethylpyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
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C23H25ClN8O
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1
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| 1 |
IC50 = 5200 nM
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CP0547460
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(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((5-methyloxazol-2-yl)methyl)piperidin-1-yl)prop-2-en-1-one
Show/Hide
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C22H25ClN6O2
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1
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| 1 |
IC50 = 5200 nM
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CP0381629
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2-[2-(5-fluoropyridin-2-yl)ethyl]-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C24H19F4N3O3
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1
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| 1 |
IC50 = 5300 nM
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CP0239554
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(3R)-3-(3,4-dichlorophenyl)-1-(2-methoxyethyl)-2,3,4,7-tetrahydroazepine
Show/Hide
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C15H19Cl2NO
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1
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| 1 |
IC50 = 5300 nM
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CP0046509
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1-[4-[4-[(5-chloro-4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]pyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
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C21H21ClN8O
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1
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| 1 |
IC50 = 5400 nM
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CP0549898
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4-[[1-(5-cyanopyridin-2-yl)piperidin-4-yl]amino]-6-[(6-methylpyrazin-2-yl)amino]pyridine-3-carboxamide
Show/Hide
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C22H23N9O
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1
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| 1 |
IC50 = 5400 nM
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CP0381633
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3-oxo-2-(2-pyridin-3-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C24H20F3N3O3
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1
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| 1 |
IC50 = 5500 nM
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CP0461026
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2-[2-(5-fluoropyrimidin-2-yl)ethyl]-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C23H18F4N4O3
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1
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| 1 |
IC50 = 5500 nM
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CP0088935
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N-(azetidin-3-ylmethyl)-N-[(3,4-dichlorophenyl)methyl]propan-2-amine;hydrochloride
Show/Hide
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C14H21Cl3N2
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1
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| 1 |
IC50 = 5500 nM
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CP0405002
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7-fluoro-3-oxo-2-(2-pyridin-2-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C24H19F4N3O3
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1
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| 1 |
IC50 = 5600 nM
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CP0449609
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7-methyl-3-oxo-2-(2-pyridin-2-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C25H22F3N3O3
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1
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| 1 |
IC50 = 5600 nM
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CP0409689
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5-[5-(methoxymethyl)pyridin-3-yl]-N-(oxan-4-ylmethyl)-1H-indazole-3-carboxamide
Show/Hide
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C21H24N4O3
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1
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| 1 |
IC50 = 5700 nM
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CP0487475
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1-[3-(6-fluoro-1H-benzimidazol-2-yl)-5-(3-fluoro-5-methylphenyl)pyridin-4-yl]piperidin-4-amine
Show/Hide
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C24H23F2N5
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1
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| 1 |
IC50 = 5700 nM
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CP0391895
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4-[5-[5-[[(1E)-1-ethoxyimino-2,3-dihydroinden-5-yl]oxy]pentyl]-1,1-dioxo-1,2,5-thiadiazolidin-2-yl]pyridin-2-amine
Show/Hide
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C23H31N5O4S
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1
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| 1 |
IC50 = 6000 nM
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CP0156814
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3-(3,4-dichlorophenyl)azepane
Show/Hide
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C12H15Cl2N
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1
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| 1 |
IC50 = 6100 nM
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CP0446346
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2-[(4aR,6S,8aR)-2-amino-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-8a-yl]-N-(3-methoxyphenyl)-1,3-thiazole-5-carboxamide
Show/Hide
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C19H22N4O3S2
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1
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| 1 |
IC50 = 6200 nM
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CP0498966
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N-[[6-(4-fluoro-2-methoxyphenyl)pyridin-2-yl]methyl]cyclopentanamine
Show/Hide
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C18H21FN2O
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1
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| 1 |
IC50 = 6230 nM
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CP0482375
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(2R)-9-[2-(2-fluorophenyl)ethyl]-2-methyl-4-[4-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C23H25F4N3O2
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1
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| 1 |
IC50 = 6300 nM
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CP0902706
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4-(4-fluorobenzoyl)-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
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C25H30FN3O5
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1
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| 1 |
IC50 = 6309.57 nM
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CP0226766
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2-[[(1S,2R)-2-aminocyclohexyl]amino]-4-(3-methylanilino)pyrimidine-5-carboxamide
Show/Hide
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C18H24N6O
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1
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| 1 |
IC50 = 6309.57 nM
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CP0426947
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N-[4-[5-[3-[(1S,4R)-2-azabicyclo[2.2.1]heptan-2-yl]propylamino]-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
Show/Hide
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C24H26FN5O2
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1
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| 1 |
IC50 = 6309.57 nM
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CP0489263
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2-fluoro-N-[2-fluoro-4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C23H25F2N5O2
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1
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| 1 |
IC50 = 6309.57 nM
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CP0519795
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N-[4-[5-[3-(azepan-1-yl)propylamino]-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
Show/Hide
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C24H28FN5O2
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1
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| 1 |
IC50 = 6309.57 nM
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CP0010657
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CAS_99200-09-6
Show/Hide
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C22H25F2NO4
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1
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| 1 |
IC50 = 6309.57 nM
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CP0468325
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3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-benzylquinolin-2-yl]propanoic acid
Show/Hide
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C40H50N4O3
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1
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| 1 |
IC50 = 6309.57 nM
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CP0560815
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3-[2-(2,4-difluorophenyl)-2-oxoethyl]-5-methyl-5-[4-(tetrazol-1-yl)phenyl]imidazolidine-2,4-dione
Show/Hide
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C19H14F2N6O3
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1
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| 1 |
IC50 = 6309.57 nM
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CP0912527
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6-(7-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)heptylamino)-5,6,7,8-tetrahydroquinolin-2(1H)-one
Show/Hide
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C29H37ClN4O
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1
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| 1 |
IC50 = 6357 nM
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CP0566501
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1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3-ethoxypyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
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C23H25ClN8O2
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1
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| 1 |
IC50 = 6400 nM
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CP0408602
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2-[2-(6-methylpyridin-2-yl)ethyl]-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C25H22F3N3O3
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1
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| 1 |
IC50 = 6600 nM
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CP0180485
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1-[4-[4-[(5-chloro-4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]-3-methoxypyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
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C22H23ClN8O2
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1
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| 1 |
IC50 = 6600 nM
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CP0476470
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(2R)-9-[2-(2-fluorophenyl)ethyl]-2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C23H25F4N3O2
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1
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| 1 |
IC50 = 6600 nM
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CP0271443
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4-[[1-(5-cyanopyridin-2-yl)piperidin-4-yl]amino]-6-[(2-methyl-1,3-benzoxazol-5-yl)amino]pyridine-3-carboxamide
Show/Hide
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C25H24N8O2
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1
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| 1 |
IC50 = 6600 nM
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CP0957066
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5-(2,3-Difluorophenyl)-N-(tetrahydro-2H-pyran-3-yl)-1H-indazole-3-carboxamide
Show/Hide
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C19H17F2N3O2
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1
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| 1 |
IC50 = 6600 nM
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CP0513151
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N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]propan-2-amine
Show/Hide
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C16H19FN2O
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1
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| 1 |
IC50 = 6670 nM
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CP0418594
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[9-[(2,2-dimethyl-3H-1-benzofuran-4-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyridin-4-ylmethanone
Show/Hide
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C26H33N3O2
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1
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| 1 |
IC50 = 7079.46 nM
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CP0342282
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N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]pyrazine-2-carboxamide
Show/Hide
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C18H15FN4O2
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1
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| 1 |
IC50 = 7110 nM
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CP0559560
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1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3-methylpyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
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C22H23ClN8O
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1
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| 1 |
IC50 = 7200 nM
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CP0404999
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3-oxo-2-(2-pyridin-2-ylethyl)-N-[1-[4-(2,2,2-trifluoroethoxy)phenyl]ethyl]-1H-isoindole-1-carboxamide
Show/Hide
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C26H24F3N3O3
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1
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| 1 |
IC50 = 7300 nM
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CP0260475
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US9409895, 32
Show/Hide
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C20H23Cl2N3O5
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1
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| 1 |
IC50 = 7300 nM
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CP0564270
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N-[4-(4-aminopiperidin-1-yl)-5-(3,5-dichlorophenyl)pyridin-3-yl]-1-methyl-5-(trifluoromethyl)pyrazole-4-carboxamide
Show/Hide
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C22H21Cl2F3N6O
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1
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| 1 |
IC50 = 7300 nM
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CP0564268
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1-[3-(6-fluoro-1H-benzimidazol-2-yl)-5-(3-fluoro-5-methoxyphenyl)pyridin-4-yl]piperidin-4-amine
Show/Hide
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C24H23F2N5O
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1
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| 1 |
IC50 = 7500 nM
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CP0704391
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rac-3-(3,4-Dichloro-phenyl)-1-methyl-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
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C13H15Cl2N
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1
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| 1 |
IC50 = 7600 nM
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CP0955093
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6-(5-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)pentylamino)-5,6,7,8-tetrahydroquinolin-2(1H)-one
Show/Hide
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C27H33ClN4O
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1
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| 1 |
IC50 = 7657 nM
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CP0389791
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4-[[(1R,2R,3aS,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
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C22H31N3O
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1
|
| 1 |
IC50 = 7700 nM
|
|
|
|
CP0271444
|
4-[[1-(5-cyanopyridin-2-yl)piperidin-4-yl]amino]-6-(pyrazin-2-ylamino)pyridine-3-carboxamide
Show/Hide
|
C21H21N9O
|
1
|
| 1 |
IC50 = 7700 nM
|
|
|
|
CP0046511
|
2-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]-N,N-dimethylacetamide
Show/Hide
|
C25H30ClN9O
|
1
|
| 1 |
IC50 = 7800 nM
|
|
|
|
CP0845130
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(3,5-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H33F2N3O5
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0860703
|
4-(3,5-difluorobenzoyl)-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one
Show/Hide
|
C24H27F2N3O3
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0069961
|
2-[[(3S,4S)-4-aminooxan-3-yl]amino]-4-(3-methylanilino)pyrimidine-5-carboxamide
Show/Hide
|
C17H22N6O2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0223907
|
2-[[(1R,2S)-2-amino-5,5-difluorocyclohexyl]amino]-4-(3-methylanilino)pyrimidine-5-carboxamide
Show/Hide
|
C18H22F2N6O
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0408671
|
2-fluoro-N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C23H26FN5O2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0415787
|
N-[4-[5-[3-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]propylamino]-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
Show/Hide
|
C24H28FN5O2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0426946
|
2-fluoro-N-[4-[5-(3-pyrrolidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C22H24FN5O2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0428410
|
2-fluoro-N-[4-[5-[3-(4-fluoropiperidin-1-yl)propylamino]-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C23H25F2N5O2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0389756
|
2,6-difluoro-N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C23H25F2N5O2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0408674
|
3-fluoro-N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C23H26FN5O2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0519797
|
2-methyl-N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C24H29N5O2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0450310
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline
Show/Hide
|
C30H40N4O
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0485843
|
N-[[(3S)-4,4-difluoropiperidin-3-yl]methyl]-7-[6-(dimethylamino)pyridin-3-yl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
|
C20H23F2N7
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0565243
|
7-(4-methylphenyl)-5-[[(3S)-piperidin-3-yl]methylamino]-3H-pyrido[4,3-d]pyrimidin-4-one
Show/Hide
|
C20H23N5O
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0835385
|
6-(4-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)butylamino)-5,6,7,8-tetrahydroquinolin-2(1H)-one
Show/Hide
|
C26H31ClN4O
|
1
|
| 1 |
IC50 = 8069 nM
|
|
|
|
CP0175864
|
4-[[1-(5-cyanopyridin-2-yl)piperidin-4-yl]amino]-6-[(2-methylpyrimidin-4-yl)amino]pyridine-3-carboxamide
Show/Hide
|
C22H23N9O
|
1
|
| 1 |
IC50 = 8100 nM
|
|
|
|
CP0381631
|
4-fluoro-3-oxo-2-(2-pyridin-2-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C24H19F4N3O3
|
1
|
| 1 |
IC50 = 8200 nM
|
|
|
|
CP0435816
|
2-methyl-9-(2-phenylethyl)-4-[3-(trifluoromethyl)pyridin-2-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H26F3N3O2
|
1
|
| 1 |
IC50 = 8200 nM
|
|
|
|
CP0557722
|
1-[3-(3-fluoro-5-methoxyphenyl)-5-(6-methyl-1H-benzimidazol-2-yl)pyridin-4-yl]piperidin-4-amine
Show/Hide
|
C25H26FN5O
|
1
|
| 1 |
IC50 = 8300 nM
|
|
|
|
CP0381628
|
3-oxo-2-(1-pyridin-2-ylpropan-2-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C25H22F3N3O3
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0445250
|
3-oxo-2-(2-pyridin-2-ylethyl)-N-[[4-(trifluoromethyl)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C24H20F3N3O2
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0480989
|
4-[[(1R,2R,3aR,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-fluoro-7a-methyl-1,2,3,3a,6,7-hexahydroinden-1-yl]oxy]benzonitrile
Show/Hide
|
C22H28FN3O
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0249946
|
US9409895, 35
Show/Hide
|
C19H23Cl2N5O3
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0487476
|
1-[3-(3,5-dimethoxyphenyl)-5-(6-methyl-1H-benzimidazol-2-yl)pyridin-4-yl]piperidin-4-amine
Show/Hide
|
C26H29N5O2
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0565374
|
[4-[2-[4-[[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]phenyl]-piperazin-1-ylmethanone
Show/Hide
|
C32H37FN6O
|
1
|
| 1 |
IC50 = 8610 nM
|
|
|
|
CP0509289
|
3-(4-fluoro-2-methoxyphenyl)-5-(pyrrolidin-2-yl)pyridine
Show/Hide
|
C16H17FN2O
|
1
|
| 1 |
IC50 = 8620 nM
|
|
|
|
CP0013001
|
(+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-indan-1-one
Show/Hide
|
C24H29NO3
|
1
|
| 1 |
IC50 = 8718 nM
|
|
|
|
CP0254738
|
US9409895, 19
Show/Hide
|
C18H21Cl2N5O3
|
1
|
| 1 |
IC50 = 8800 nM
|
|
|
|
CP0426125
|
3-oxo-2-(2-pyridin-2-ylethyl)-N-[[4-(2,2,2-trifluoroethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C25H22F3N3O3
|
1
|
| 1 |
IC50 = 8900 nM
|
|
|
|
CP0826607
|
6-(3-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)propylamino)-5,6,7,8-tetrahydroquinolin-2(1H)-one
Show/Hide
|
C25H29ClN4O
|
1
|
| 1 |
IC50 = 8975 nM
|
|
|
|
CP0266599
|
1-[6-[(4-fluorophenyl)methyl]-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazin-1-yl]ethanone
Show/Hide
|
C29H40FN5O2
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0124822
|
US9315520, 7
Show/Hide
|
C17H18ClN5O2S2
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0389051
|
4-[5-[5-[4-[(E)-ethoxyiminomethyl]phenoxy]pentyl]-1,1-dioxo-1,2,5-thiadiazolidin-2-yl]pyridin-2-amine
Show/Hide
|
C21H29N5O4S
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0429527
|
3-oxo-2-(2-pyrazin-2-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C23H19F3N4O3
|
1
|
| 1 |
IC50 = 9200 nM
|
|
|
|
CP0381635
|
N-[(4-bromophenyl)methyl]-3-oxo-2-(2-pyridin-2-ylethyl)-1H-isoindole-1-carboxamide
Show/Hide
|
C23H20BrN3O2
|
1
|
| 1 |
IC50 = 9300 nM
|
|
|
|
CP0555539
|
2-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]ethanol
Show/Hide
|
C23H27ClN8O
|
1
|
| 1 |
IC50 = 9300 nM
|
|
|
|
CP0327531
|
US9409895, 20
Show/Hide
|
C20H25Cl2N5O3
|
1
|
| 1 |
IC50 = 9300 nM
|
|
|
|
CP0232211
|
N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-1,3-thiazol-4-yl}-1-(difluoromethyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C16H18F2N6O2S2
|
1
|
| 1 |
IC50 = 9300 nM
|
|
|
|
CP0681610
|
4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C28H32N4O5
|
1
|
| 1 |
IC50 = 9332.54 nM
|
|
|
|
CP0527174
|
5-(4-fluoro-2-methoxyphenyl)-N-(tetrahydro-2H-pyran-3-yl)pyridin-3-amine
Show/Hide
|
C17H19FN2O2
|
1
|
| 1 |
IC50 = 9400 nM
|
|
|
|
CP0018951
|
N-(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-ylmethyl)-2-[2-(6-methoxyquinolin-4-yl)ethyl]-1,3-dioxan-5-amine
Show/Hide
|
C24H27N3O5
|
1
|
| 1 |
IC50 = 9500 nM
|
|
|
|
CP0097508
|
US9315520, 45
Show/Hide
|
C19H21F2N5O3S2
|
1
|
| 1 |
IC50 = 9600 nM
|
|
|
|
CP0445686
|
2-(2,2-difluoro-2-pyridin-2-ylethyl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C24H18F5N3O3
|
1
|
| 1 |
IC50 = 9700 nM
|
|
|
|
CP0088772
|
3-(4-methoxyphenyl)-7-(2-methylphenyl)thieno[3,2-d]pyrimidin-4-one
Show/Hide
|
C20H16N2O2S
|
1
|
| 1 |
IC50 = 9870 nM
|
|
|
|
CP0097523
|
US9315520, 1
Show/Hide
|
C18H19F2N5O3S2
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0200067
|
N-(piperidin-4-ylmethyl)-3-[3-(trifluoromethoxy)phenyl]triazolo[4,5-b]pyridin-5-amine
Show/Hide
|
C18H19F3N6O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0430640
|
2-fluoro-N-[3-fluoro-4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C23H25F2N5O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0489261
|
4-fluoro-N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C23H26FN5O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0239558
|
(3R)-3-(3,4-dichlorophenyl)-1-methyl-2,3,4,7-tetrahydroazepine
Show/Hide
|
C13H15Cl2N
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0261048
|
2-[(3R)-3-(3,4-dichlorophenyl)-2,3,4,7-tetrahydroazepin-1-yl]ethanol
Show/Hide
|
C14H17Cl2NO
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0285760
|
3-(3,4-dichlorophenyl)-1-methylazepane
Show/Hide
|
C13H17Cl2N
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0002211
|
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C22H27FN4O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0008168
|
CAS_136434-34-9
Show/Hide
|
C18H19NOS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0223062
|
1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3-methoxypyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C22H23ClN8O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0324869
|
8-[2-(2-fluorophenyl)ethyl]-12-[2-(trifluoromethyl)pyridin-3-yl]-4-oxa-8,12-diazadispiro[2.1.55.33]tridecan-13-one
Show/Hide
|
C24H25F4N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0444476
|
N-[3-[2-(2-methyl-3-oxo-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)ethyl]phenyl]acetamide
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0444499
|
N-[3-[2-[(2R)-2-methyl-3-oxo-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl]ethyl]phenyl]acetamide
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0528271
|
[5-(3-methylsulfonyl-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C17H16N2O4S3
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0255249
|
N,N-dimethyl-5-[5-[[(3S)-piperidin-3-yl]methoxy]pyrido[3,4-b]pyrazin-7-yl]pyridin-2-amine
Show/Hide
|
C20H24N6O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0463551
|
7-(4-methylphenyl)-N-[[(3S)-piperidin-3-yl]methyl]pyrido[4,3-d]pyrimidin-5-amine
Show/Hide
|
C20H23N5
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0446351
|
US9315520, 20
Show/Hide
|
C18H18F3N5O3S2
|
1
|
| 1 |
IC50 = 10100 nM
|
|
|
|
CP0097502
|
US9315520, 9
Show/Hide
|
C17H18FN5O2S2
|
1
|
| 1 |
IC50 = 10700 nM
|
|
|
|
CP0343858
|
3-(4-methoxyphenyl)-7-phenylthieno[3,2-d]pyrimidin-4-one
Show/Hide
|
C19H14N2O2S
|
1
|
| 1 |
IC50 = 10800 nM
|
|
|
|
CP0087786
|
1-methyl-3-oxo-2-(2-pyridin-2-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]isoindole-1-carboxamide
Show/Hide
|
C25H22F3N3O3
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0435277
|
tert-butyl 3-[3-oxo-1-[[4-(trifluoromethoxy)phenyl]methylcarbamoyl]-1H-isoindol-2-yl]azetidine-1-carboxylate
Show/Hide
|
C25H26F3N3O5
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0770079
|
rac-3-(3,4-Dichloro-phenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C12H13Cl2N
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0944976
|
5-(2,3-Difluorophenyl)-N-((tetrahydrofuran-2-yl)methyl)-1H-indazole-3-carboxamide
Show/Hide
|
C19H17F2N3O2
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0373960
|
[9-[(2,2-dimethyl-3,4-dihydrochromen-6-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyrimidin-4-ylmethanone
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
IC50 = 11220.18 nM
|
|
|
|
CP0401245
|
(5-aminopyridin-2-yl)-[9-[(2-tert-butyl-2-methyl-3H-1-benzofuran-4-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
|
C29H40N4O2
|
1
|
| 1 |
IC50 = 11220.18 nM
|
|
|
|
CP0968905
|
6-(6-(6-chloro-1,2,3,4-tetrahydroacridin-9-ylamino)hexylamino)-5,6,7,8-tetrahydroquinolin-2(1H)-one
Show/Hide
|
C28H35ClN4O
|
1
|
| 1 |
IC50 = 11637 nM
|
|
|
|
CP0179937
|
US9315520, 17
Show/Hide
|
C18H18F3N5O2S2
|
1
|
| 1 |
IC50 = 11700 nM
|
|
|
|
CP0133961
|
2-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]-N-methylacetamide
Show/Hide
|
C24H28ClN9O
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0023683
|
N-(3,4-dihydro-2H-pyrano[2,3-c]pyridin-6-ylmethyl)-2-[2-(6-methoxyquinolin-4-yl)ethyl]-1,3-dioxan-5-amine
Show/Hide
|
C25H29N3O4
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0230989
|
3-[4-[(3S)-3-[(4-chlorophenyl)methyl]morpholin-4-yl]piperidin-1-yl]-1H-1,2,4-triazol-5-amine
Show/Hide
|
C18H25ClN6O
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0511870
|
(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((3-methylisoxazol-5-yl)methyl)piperazin-1-yl)prop-2-en-1-one
Show/Hide
|
C21H24ClN7O2
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0484759
|
N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-1,3-thiazol-4-yl}-5-cyanopyridine-2-carboxamide
Show/Hide
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C18H18N6O2S2
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1
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| 1 |
IC50 = 12100 nM
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CP0845126
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1-(4-(3-(azepan-1-yl)propoxy)phenyl)-4-(4-fluorobenzoyl)piperazin-2-one formic acid
Show/Hide
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C27H34FN3O5
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1
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| 1 |
IC50 = 12589.25 nM
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CP0854444
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(S)-4-(3,5-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
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C26H31F2N3O5
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1
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| 1 |
IC50 = 12589.25 nM
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CP0890878
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4-(1-(4-(3-(azepan-1-yl)propoxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
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C28H34N4O5
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1
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| 1 |
IC50 = 12589.25 nM
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CP0900120
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1-(4-(3-(azepan-1-yl)propoxy)phenyl)-4-(3,5-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
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C27H33F2N3O5
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1
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| 1 |
IC50 = 12589.25 nM
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CP0209320
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2-fluoro-N-[4-[5-(4-piperidin-1-ylbutylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C24H28FN5O2
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1
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| 1 |
IC50 = 12589.25 nM
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CP0415789
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2-fluoro-N-[4-[5-[4-(1,4-oxazepan-4-yl)butylamino]-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C24H28FN5O3
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1
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| 1 |
IC50 = 12589.25 nM
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CP0428407
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N-[4-[5-[3-(1,4-diazabicyclo[3.2.2]nonan-4-yl)propylamino]-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
Show/Hide
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C25H29FN6O2
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1
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| 1 |
IC50 = 12589.25 nM
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CP0490915
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2-fluoro-N-[4-[5-(4-pyrrolidin-1-ylbutylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C23H26FN5O2
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1
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| 1 |
IC50 = 12589.25 nM
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CP0389758
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N-[3-ethoxy-4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
Show/Hide
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C25H30FN5O3
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1
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| 1 |
IC50 = 12589.25 nM
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CP0416793
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N-[4-[5-[3-(diethylamino)propylamino]-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
Show/Hide
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C22H26FN5O2
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1
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| 1 |
IC50 = 12589.25 nM
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CP0430636
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2-chloro-N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C23H26ClN5O2
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1
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| 1 |
IC50 = 12589.25 nM
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CP0368705
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N,N-dimethyl-5-[5-[[(3R)-piperidin-3-yl]methoxy]pyrido[3,4-b]pyrazin-7-yl]pyridin-2-amine
Show/Hide
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C20H24N6O
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1
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| 1 |
IC50 = 12589.25 nM
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CP0456376
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4-[[(1R,2R,3aR,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5,5-difluoro-7a-methyl-2,3,3a,4,6,7-hexahydro-1H-inden-1-yl]oxy]benzonitrile
Show/Hide
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C22H29F2N3O
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1
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| 1 |
IC50 = 13000 nM
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CP0369611
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US9315520, 19
Show/Hide
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C18H21N5O3S2
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1
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| 1 |
IC50 = 13100 nM
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CP0944977
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5-(2,3-Difluorophenyl)-N-(tetrahydrofuran-3-yl)-1H-indazole-3-carboxamide
Show/Hide
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C18H15F2N3O2
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1
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| 1 |
IC50 = 13300 nM
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CP0684741
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4-{[1-(5-Cyanopyridin-2-yl)piperidin-4-yl]amino}-1Hpyrrolo[2,3-b]pyridine-5-carboxamide
Show/Hide
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C19H19N7O
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1
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| 1 |
IC50 = 13400 nM
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CP0262848
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(3S)-3-(3,4-dichlorophenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
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C12H13Cl2N
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1
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| 1 |
IC50 = 13700 nM
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CP0449592
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3-oxo-2-(2-pyridin-2-ylethyl)-N-[[4-(2,2,2-trifluoroethyl)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C25H22F3N3O2
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1
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| 1 |
IC50 = 14000 nM
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CP0456749
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tert-butyl 4-[3-oxo-1-[[4-(trifluoromethoxy)phenyl]methylcarbamoyl]-1H-isoindol-2-yl]piperidine-1-carboxylate
Show/Hide
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C27H30F3N3O5
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1
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| 1 |
IC50 = 14000 nM
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CP0555856
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(E)-1-(4-(3-Methyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one
Show/Hide
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C21H22F3N7O2
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1
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| 1 |
IC50 = 14000 nM
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CP0374034
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3-[9-[[2-(2-methoxyphenoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecane-3-carbonyl]-1H-pyridin-2-one
Show/Hide
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C29H33N3O4
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1
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| 1 |
IC50 = 14125.38 nM
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CP0001598
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1,2,3,4-tetrahydro-9-acridinamine
Show/Hide
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C13H14N2
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1
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| 1 |
IC50 = 14312 nM
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CP0944978
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5-(2,3-Difluorophenyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1H-indazole-3-carboxamide
Show/Hide
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C18H15F2N3O3S
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1
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| 1 |
IC50 = 14500 nM
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CP0470498
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2-[[1-(4-fluorophenyl)-5-propan-2-ylpyrazol-3-yl]methyl]-3H-1,2-benzothiazole 1,1-dioxide
Show/Hide
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C20H20FN3O2S
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1
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| 1 |
IC50 = 14700 nM
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CP0145994
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3-(1-benzofuran-2-yl)-1-methyl-2,3,4,7-tetrahydroazepine
Show/Hide
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C15H17NO
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1
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| 1 |
IC50 = 15000 nM
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CP0482700
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4-[[(1R,2R,3aS,5S,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-(difluoromethyl)-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
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C23H31F2N3O
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1
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| 1 |
IC50 = 15000 nM
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CP0189386
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6-[6-[3-(dimethylamino)propoxy]pyridin-3-yl]-N-methyl-4-[[(1S)-1-(oxan-4-yl)ethyl]amino]cinnoline-3-carboxamide
Show/Hide
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C27H36N6O3
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1
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| 1 |
IC50 = 15000 nM
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CP0471035
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3-benzoyl-N-[[5-(2-methylpropyl)-1-phenylpyrazol-3-yl]methyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
Show/Hide
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C27H30N4O2
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1
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| 1 |
IC50 = 15000 nM
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CP0554881
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(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((1-methyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)prop-2-en-1-one
Show/Hide
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C21H25ClN8O
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1
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| 1 |
IC50 = 15000 nM
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CP0239557
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3-naphthalen-2-yl-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
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C16H17N
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1
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| 1 |
IC50 = 15400 nM
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CP0108321
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(4aR,6S,8aS)-8a-(2,4-difluorophenyl)-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
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C14H16F2N2OS
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1
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| 1 |
IC50 = 15800 nM
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CP0415793
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2-fluoro-N-[3-methoxy-4-[5-(4-piperidin-1-ylbutylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C25H30FN5O3
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1
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| 1 |
IC50 = 15848.93 nM
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CP0415794
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2-fluoro-N-[4-[5-[4-(4-fluoropiperidin-1-yl)butylamino]-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C24H27F2N5O2
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1
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| 1 |
IC50 = 15848.93 nM
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CP0432104
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N-[3-fluoro-4-[5-(4-morpholin-4-ylbutylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C23H26FN5O3
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1
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| 1 |
IC50 = 15848.93 nM
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CP0389759
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N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C23H27N5O2
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1
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| 1 |
IC50 = 15848.93 nM
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CP0416794
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2-fluoro-N-[2-methyl-4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C24H28FN5O2
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1
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| 1 |
IC50 = 15848.93 nM
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CP0523653
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2-fluoro-N-[3-methoxy-4-[5-(3-morpholin-4-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C23H26FN5O4
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1
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| 1 |
IC50 = 15848.93 nM
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CP0450308
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3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-2-yl]propanoic acid
Show/Hide
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C33H44N4O3
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1
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| 1 |
IC50 = 15848.93 nM
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CP0213833
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N'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine
Show/Hide
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C18H21N5
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1
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| 1 |
IC50 = 15848.93 nM
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CP0528542
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7-[6-(dimethylamino)pyridin-3-yl]-N-[[(2R)-1-methylpiperazin-2-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C20H26N8
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1
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| 1 |
IC50 = 15848.93 nM
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CP0530525
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7-(4-methylphenyl)-N-[[(3S)-piperidin-3-yl]methyl]-1,6-naphthyridin-5-amine
Show/Hide
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C21H24N4
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1
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| 1 |
IC50 = 15848.93 nM
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CP0545546
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N,N-dimethyl-5-[5-(2-piperidin-3-ylethyl)pyrido[3,4-b]pyrazin-7-yl]pyridin-2-amine
Show/Hide
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C21H26N6
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1
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| 1 |
IC50 = 15848.93 nM
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CP0528898
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N-[[6-(4-fluoro-2-methoxyphenyl)pyrazin-2-yl]methyl]cyclopentanamine
Show/Hide
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C17H20FN3O
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1
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| 1 |
IC50 = 16000 nM
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CP0381634
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3-oxo-2-(2-pyridin-2-ylethyl)-N-[[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C24H21F3N4O3
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1
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| 1 |
IC50 = 16000 nM
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CP0488683
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3-oxo-2-(2-pyrimidin-2-ylethyl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C23H19F3N4O3
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1
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| 1 |
IC50 = 16000 nM
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CP0376952
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(5-aminopyridin-2-yl)-[9-[(2,2-dimethyl-3H-1-benzofuran-4-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
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C26H34N4O2
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1
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| 1 |
IC50 = 16595.87 nM
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CP0447656
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(2-aminopyridin-4-yl)-[9-[(2,2-dimethyl-1,3-benzodioxol-4-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
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C25H32N4O3
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1
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| 1 |
IC50 = 16595.87 nM
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CP0394364
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5-fluoro-3-[3-[4-(4-fluoro-2-phenylphenyl)piperazin-1-yl]propyl]-1H-indole
Show/Hide
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C27H27F2N3
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1
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| 1 |
IC50 = 16660 nM
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CP0445311
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3-oxo-2-[[(2S)-oxolan-2-yl]methyl]-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
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C22H21F3N2O4
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1
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| 1 |
IC50 = 17000 nM
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CP0180486
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1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]-2-methoxyethanone
Show/Hide
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C24H27ClN8O2
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1
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| 1 |
IC50 = 17000 nM
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CP0350255
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1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-5-ethylpyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
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C23H25ClN8O
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1
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| 1 |
IC50 = 17000 nM
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CP0485521
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4-[[(1S,2R,3R,4R,6R,7S)-4-[(3R)-3-aminopiperidin-1-yl]-9-oxo-3-tricyclo[5.2.1.02,6]decanyl]oxy]benzonitrile
Show/Hide
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C22H27N3O2
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1
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| 1 |
IC50 = 17000 nM
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CP0368393
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4-[[1-(5-cyanopyridin-2-yl)piperidin-4-yl]amino]-6-(pyrimidin-4-ylamino)pyridine-3-carboxamide
Show/Hide
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C21H21N9O
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1
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| 1 |
IC50 = 17000 nM
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CP0539849
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4-[(E)-3-[4-chloro-2-[(5-methyltetrazol-2-yl)methyl]phenyl]prop-2-enoyl]-1-[(3-methyl-1,2-oxazol-5-yl)methyl]piperazin-2-one
Show/Hide
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C21H22ClN7O3
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1
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| 1 |
IC50 = 17000 nM
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CP0076103
|
US9315520, 13
Show/Hide
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C18H20FN5O2S2
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1
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| 1 |
IC50 = 17900 nM
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CP0346856
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N-[2-[(4aR,6S,8aR)-2-amino-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-8a-yl]-1,3-thiazol-4-yl]-4-methoxybenzamide
Show/Hide
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C19H22N4O3S2
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1
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| 1 |
IC50 = 18400 nM
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CP0456353
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N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]cyclobutanecarboxamide
Show/Hide
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C18H19FN2O2
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1
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| 1 |
IC50 = 18600 nM
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CP0478186
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N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]benzamide
Show/Hide
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C20H17FN2O2
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1
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| 1 |
IC50 = 18800 nM
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CP0208587
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3-(1-benzofuran-2-yl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C14H15NO
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1
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| 1 |
IC50 = 19000 nM
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CP0528637
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(E)-3-[2-[(5-methyltetrazol-2-yl)methyl]-4-(trifluoromethyl)phenyl]-1-[4-(trifluoromethyl)piperidin-1-yl]prop-2-en-1-one
Show/Hide
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C19H19F6N5O
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1
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| 1 |
IC50 = 19000 nM
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CP0446775
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2-[(1-tert-butyl-5-propan-2-ylpyrazol-3-yl)methyl]-3H-1,2-benzothiazole 1,1-dioxide
Show/Hide
|
C18H25N3O2S
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1
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| 1 |
IC50 = 19300 nM
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CP0401261
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(5-aminopyridin-2-yl)-[9-[(2,2-dimethyl-3,4-dihydrochromen-6-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
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C27H36N4O2
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1
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| 1 |
IC50 = 19498.45 nM
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CP0845132
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1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(4-fluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H34FN3O5
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1
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| 1 |
IC50 = 19952.62 nM
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CP0890877
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(R)-4-(4-fluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
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C26H32FN3O5
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1
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| 1 |
IC50 = 19952.62 nM
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CP0205195
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2-[[(3R,4R)-3-aminooxan-4-yl]amino]-4-(4-methylanilino)pyrimidine-5-carboxamide
Show/Hide
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C17H22N6O2
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1
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| 1 |
IC50 = 19952.62 nM
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CP0415791
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N-[4-[5-[4-(diethylamino)butylamino]-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
Show/Hide
|
C23H28FN5O2
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1
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| 1 |
IC50 = 19952.62 nM
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CP0428408
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N-[4-[5-(4-piperidin-1-ylbutylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C24H29N5O2
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1
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| 1 |
IC50 = 19952.62 nM
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CP0428409
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2-fluoro-N-[4-[5-[3-(1,4-oxazepan-4-yl)propylamino]-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C23H26FN5O3
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1
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| 1 |
IC50 = 19952.62 nM
|
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CP0416795
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N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]cyclohexanecarboxamide
Show/Hide
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C23H33N5O2
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1
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| 1 |
IC50 = 19952.62 nM
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CP0489262
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N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]cycloheptanecarboxamide
Show/Hide
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C24H35N5O2
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1
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| 1 |
IC50 = 19952.62 nM
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CP0010652
|
ALFUZOSIN
Show/Hide
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C19H27N5O4
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1
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| 1 |
IC50 = 19952.62 nM
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CP0450307
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8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-3-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
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| 1 |
IC50 = 19952.62 nM
|
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CP0149810
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N-[[(3R)-4,4-difluoropiperidin-3-yl]methyl]-7-[6-(dimethylamino)pyridin-3-yl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
|
C20H23F2N7
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1
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| 1 |
IC50 = 19952.62 nM
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CP0255252
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7-(5-methylfuran-2-yl)-N-[[(3S)-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
|
C18H21N5O
|
1
|
| 1 |
IC50 = 19952.62 nM
|
|
|
|
CP0069850
|
(6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylimidothiocarbamate
Show/Hide
|
C21H34N4S2
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0135993
|
1,3-dicyclohexyl-2-((5,6-dihydroimidazo[2,1-b]thiazol-3-yl)methyl)isothiourea
Show/Hide
|
C19H30N4S2
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0449612
|
3-oxo-2-(2-pyridin-2-ylethyl)-N-[[6-(3,3,3-trifluoropropoxy)pyridin-3-yl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C25H23F3N4O3
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0118796
|
Cariprazine
Show/Hide
|
C21H32Cl2N4O
|
1
|
| 1 |
IC50 = 20720 nM
|
|
|
|
CP0422090
|
(6-cyclohexyl-6-azaspiro[2.5]octan-2-yl)-(4-cyclohexylpiperazin-1-yl)methanone
Show/Hide
|
C24H41N3O
|
1
|
| 1 |
IC50 = 20800 nM
|
|
|
|
CP0430149
|
N-[[5-(2-methylpropyl)-1-phenylpyrazol-3-yl]methyl]-3-(2-phenylacetyl)-3-azabicyclo[3.1.0]hexane-6-carboxamide
Show/Hide
|
C28H32N4O2
|
1
|
| 1 |
IC50 = 20800 nM
|
|
|
|
CP0401922
|
[9-[(2-methyl-2,3-dihydro-1-benzofuran-7-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-pyridin-4-ylmethanone
Show/Hide
|
C25H31N3O2
|
1
|
| 1 |
IC50 = 20892.96 nM
|
|
|
|
CP0123400
|
US9409895, 17
Show/Hide
|
C19H23Cl2N5O3
|
1
|
| 1 |
IC50 = 20900 nM
|
|
|
|
CP0381630
|
3-oxo-2-(2-pyridin-2-ylethyl)-N-[[3-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C24H20F3N3O3
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0333998
|
(3R)-3-(3,4-dichlorophenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C12H13Cl2N
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0307981
|
1-[4-[4-[(5-chloro-4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]-5-methylpyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C22H23ClN8O
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0449591
|
2-[2-(oxan-4-yl)ethyl]-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C24H25F3N2O4
|
1
|
| 1 |
IC50 = 22000 nM
|
|
|
|
CP0202712
|
1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]-2-hydroxyethanone
Show/Hide
|
C23H25ClN8O2
|
1
|
| 1 |
IC50 = 22000 nM
|
|
|
|
CP0878600
|
5-(2,3-Difluorophenyl)-N-((tetrahydro-2H-pyran-3-yl)methyl)-1H-indazole-3-carboxamide
Show/Hide
|
C20H19F2N3O2
|
1
|
| 1 |
IC50 = 22300 nM
|
|
|
|
CP0396386
|
2-(3,3-difluorocyclobutyl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C21H17F5N2O3
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0145943
|
3-(3-chloro-4-fluorophenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C12H13ClFN
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0018335
|
1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C23H25ClN8O
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0046512
|
(2S)-1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]-2-hydroxypropan-1-one
Show/Hide
|
C24H27ClN8O2
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0686385
|
(S)-3-(4-(3-(4-chlorobenzyl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Show/Hide
|
C23H27ClN6O
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0539848
|
(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((2-methyloxazol-4-yl)methyl)piperazin-1-yl)prop-2-en-1-one
Show/Hide
|
C21H24ClN7O2
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0547723
|
(E)-1-(4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one
Show/Hide
|
C21H22F3N7O2
|
1
|
| 1 |
IC50 = 23000 nM
|
|
|
|
CP0097501
|
N-{2-[(4aR,6S,8aR)-2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-1,3-thiazol-4-yl}-5-(difluoromethoxy)pyrazine-2-carboxamide
Show/Hide
|
C17H18F2N6O3S2
|
1
|
| 1 |
IC50 = 23600 nM
|
|
|
|
CP0449607
|
2-[2-(5-fluoropyrimidin-2-yl)ethyl]-3-oxo-N-[[3-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C23H18F4N4O3
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0133966
|
5-chloro-N-(3,5-dimethyl-1-piperidin-4-ylpyrazol-4-yl)-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-amine
Show/Hide
|
C21H23ClN8
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0123998
|
6-[6-[3-(dimethylamino)propoxy]pyridin-3-yl]-4-[[(1S)-1-(oxan-4-yl)ethyl]amino]cinnoline-3-carboxamide
Show/Hide
|
C26H34N6O3
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0478052
|
4-[[(1R,2R,3aR,5E,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-methoxyimino-7a-methyl-2,3,3a,4,6,7-hexahydro-1H-inden-1-yl]oxy]benzonitrile
Show/Hide
|
C23H32N4O2
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0486263
|
1-[(E)-3-[2-[(5-methyltetrazol-2-yl)methyl]-4-(trifluoromethyl)phenyl]prop-2-enoyl]piperidine-4-carbonitrile
Show/Hide
|
C19H19F3N6O
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0552980
|
(E)-1-(4-(3-Methyl-1H-1,2,4-triazol-1-yl)piperidin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one
Show/Hide
|
C21H23F3N8O
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0547805
|
7-[(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-3-hydroxy-8-methylquinolin-2-one
Show/Hide
|
C19H24FN3O2
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0845134
|
(S)-4-(4-fluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H32FN3O5
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0854442
|
1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(2,4-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C28H33F2N3O5
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0069962
|
2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-(4-methylanilino)pyrimidine-5-carboxamide
Show/Hide
|
C18H24N6O
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0415792
|
N-[4-[5-(4-piperidin-1-ylbutylamino)-1,3,4-oxadiazol-2-yl]phenyl]cyclohexanecarboxamide
Show/Hide
|
C24H35N5O2
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0517269
|
N-[4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]cyclopentanecarboxamide
Show/Hide
|
C22H31N5O2
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0519798
|
N-[2-ethyl-4-[5-(3-piperidin-1-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
Show/Hide
|
C25H30FN5O2
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0013593
|
1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-(2,2,2-trifluoro-ethoxy)-phenoxy]-ethylamino}-propyl)-2,3-dihydro-1H-indole-7-carboxylic acid amide
Show/Hide
|
C25H32F3N3O4
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0564631
|
4-[1-[2-(2,4-difluorophenyl)-2-oxoethyl]-4-methyl-2,5-dioxoimidazolidin-4-yl]benzonitrile
Show/Hide
|
C19H13F2N3O3
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0482662
|
7-[6-(dimethylamino)pyridin-3-yl]-N-[[(3S)-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
|
C20H25N7
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0485845
|
3-methyl-7-(4-methylphenyl)-5-[[(3S)-piperidin-3-yl]methylamino]pyrido[4,3-d]pyrimidin-4-one
Show/Hide
|
C21H25N5O
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0543111
|
5-[(4,4-difluoropiperidin-3-yl)methoxy]-7-(1-methylpyrazol-4-yl)pyrido[3,4-b]pyrazine
Show/Hide
|
C17H18F2N6O
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0550625
|
N-[[(3S)-4,4-difluoropiperidin-3-yl]methyl]-7-(1-methylpyrazol-4-yl)pyrido[3,4-b]pyrazin-5-amine
Show/Hide
|
C17H19F2N7
|
1
|
| 1 |
IC50 = 25118.86 nM
|
|
|
|
CP0418626
|
[9-[[3-(2-methoxyphenoxy)phenyl]methyl]-3,9-diazaspiro[5.5]undecan-3-yl]-(1-oxidopyridin-1-ium-4-yl)methanone
Show/Hide
|
C29H33N3O4
|
1
|
| 1 |
IC50 = 25703.96 nM
|
|
|
|
CP0426640
|
US9180116, 2C
Show/Hide
|
C21H31F2NO4
|
1
|
| 1 |
IC50 = 25900 nM
|
|
|
|
CP0429528
|
2-(2-cyanoethyl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C20H16F3N3O3
|
1
|
| 1 |
IC50 = 26000 nM
|
|
|
|
CP0239555
|
3-(4-chloro-3-methylphenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C13H16ClN
|
1
|
| 1 |
IC50 = 26000 nM
|
|
|
|
CP0262847
|
3-(4-chloro-3-methylphenyl)-1-methyl-2,3,4,7-tetrahydroazepine
Show/Hide
|
C14H18ClN
|
1
|
| 1 |
IC50 = 26000 nM
|
|
|
|
CP0241221
|
N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]pyridine-2-carboxamide
Show/Hide
|
C19H16FN3O2
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0086307
|
(+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine
Show/Hide
|
C16H18N2
|
1
|
| 1 |
IC50 > 27000 nM
|
|
|
|
CP0261049
|
3-(3-chloro-4-methylphenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C13H16ClN
|
1
|
| 1 |
IC50 > 27000 nM
|
|
|
|
CP0134116
|
1-[4-[4-[(5-chloro-4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C23H25ClN8O
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0836435
|
cis-4-{[1-(5-Cyanopyridin-2-yl)-3-methylpiperidin-4-yl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
IC50 = 28700 nM
|
|
|
|
CP0430717
|
(2-aminopyridin-4-yl)-[9-[(2,2-dimethyl-3H-1-benzofuran-4-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
IC50 = 28840.32 nM
|
|
|
|
CP0065432
|
(2R)-1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]-2-hydroxypropan-1-one
Show/Hide
|
C24H27ClN8O2
|
1
|
| 1 |
IC50 = 29000 nM
|
|
|
|
CP0133965
|
5-chloro-4-imidazo[1,2-a]pyridin-3-yl-N-(3-methyl-1-piperidin-4-ylpyrazol-4-yl)pyrimidin-2-amine
Show/Hide
|
C20H21ClN8
|
1
|
| 1 |
IC50 = 29000 nM
|
|
|
|
CP0417632
|
7-[(2R)-2-[(E,3S,4S)-3-hydroxy-4-methylnon-1-en-6-ynyl]-5-oxopyrrolidin-1-yl]heptanoic acid
Show/Hide
|
C21H33NO4
|
1
|
| 1 |
IC50 = 29000 nM
|
|
|
|
CP0426810
|
[4-[3-ethyl-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C16H18N4O2S2
|
1
|
| 1 |
IC50 = 29000 nM
|
|
|
|
CP0390426
|
4-[[(1R,2R,3aS,7aR)-2-[(3R)-3-aminopiperidin-1-yl]-7a-methyl-5-oxo-2,3,3a,4,6,7-hexahydro-1H-inden-1-yl]oxy]benzonitrile
Show/Hide
|
C22H29N3O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0475136
|
4-[[(1R,2R,3aR,6aR)-2-[(3R)-3-aminopiperidin-1-yl]-4-oxo-2,3,3a,5,6,6a-hexahydro-1H-pentalen-1-yl]oxy]benzonitrile
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0475137
|
4-[[(1R,2R,3aR,5R,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-hydroxy-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0475138
|
4-[[(1R,2R,3aR,5S,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-hydroxy-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
|
C22H31N3O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0480990
|
(2E)-2-[(1R,2R,3aS,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-1-(4-cyanophenoxy)-7a-methyl-2,3,3a,4,6,7-hexahydro-1H-inden-5-ylidene]-N,N-dimethylacetamide
Show/Hide
|
C26H36N4O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0482699
|
4-[[(1R,2R,3aR,5R,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-methoxy-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
|
C23H33N3O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0519974
|
4-[[(1R,2R,3aR,5S,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-methoxy-7a-methyl-1,2,3,3a,4,5,6,7-octahydroinden-1-yl]oxy]benzonitrile
Show/Hide
|
C23H33N3O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0391893
|
2-[5-[4-(4-chlorophenyl)phenoxy]pentyl]-5-pyridin-4-yl-1,2,5-thiadiazolidine 1,1-dioxide
Show/Hide
|
C24H26ClN3O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0486264
|
(E)-1-(4-chloropiperidin-1-yl)-3-[2-[(5-methyltetrazol-2-yl)methyl]-4-(trifluoromethyl)phenyl]prop-2-en-1-one
Show/Hide
|
C18H19ClF3N5O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0555857
|
(E)-3-(4-Chloro-2-((5-methyl-2H-tetrazol-2-yl)methyl)phenyl)-1-(4-((5-methyl-1,3,4-oxadiazol-2-yl)methyl)piperidin-1-yl)prop-2-en-1-one
Show/Hide
|
C21H24ClN7O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0570319
|
(E)-1-(4-(5-Methyl-1,2,4-oxadiazol-3-yl)piperidin-1-yl)-3-(2-((5-methyl-2H-tetrazol-2-yl)methyl)-4-(trifluoromethyl)phenyl)prop-2-en-1-one
Show/Hide
|
C21H22F3N7O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0572936
|
(2S)-5-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-6-fluoro-2-methyl-11-oxo-1-azatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraene-10-carboxylic acid
Show/Hide
|
C20H22FN3O3
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0574854
|
(13S)-8-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-7-fluoro-13-methyl-2-oxo-10-oxa-1-azatricyclo[7.4.1.05,14]tetradeca-3,5,7,9(14)-tetraene-3-carboxylic acid
Show/Hide
|
C21H24FN3O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0574858
|
(2S)-6-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-8-cyano-7-fluoro-2-methyl-12-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,10-tetraene-11-carboxylic acid
Show/Hide
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C21H21FN4O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0572058
|
(2S,4S)-4-fluoro-1-[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C19H20F2N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0390887
|
(5-aminopyridin-2-yl)-[9-[(3,3-difluoro-2,2-dimethyl-1-benzofuran-7-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
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C26H32F2N4O2
|
1
|
| 1 |
IC50 = 30902.95 nM
|
|
|
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CP0408628
|
2-(1-cyanopropan-2-yl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C21H18F3N3O3
|
1
|
| 1 |
IC50 = 31000 nM
|
|
|
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CP0142333
|
3-(4-chlorophenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C12H14ClN
|
1
|
| 1 |
IC50 > 31000 nM
|
|
|
|
CP0237238
|
3-(4-Methoxy-phenyl)-9-prop-2-ynylamino-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one
Show/Hide
|
C19H14N4O2S
|
1
|
| 1 |
IC50 = 31000 nM
|
|
|
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CP0854404
|
(S)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
|
CP0890876
|
4-(4-chlorobenzoyl)-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C26H31Cl2N3O3
|
1
|
| 1 |
IC50 = 31622.78 nM
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|
|
|
CP0896098
|
4-(4-methylbenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
|
C26H34ClN3O3
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
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CP0128906
|
3-[3-(dimethylamino)phenyl]-7-methoxy-N-(piperidin-4-ylmethyl)triazolo[4,5-b]pyridin-5-amine
Show/Hide
|
C20H27N7O
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
|
CP0408672
|
2-fluoro-N-[4-[5-(3-morpholin-4-ylpropylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C22H24FN5O3
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
|
CP0465009
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-7-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
|
CP0512424
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-3-yl]propanoic acid
Show/Hide
|
C33H44N4O3
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
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CP0255248
|
4-[[7-[6-(dimethylamino)pyridin-3-yl]pyrido[3,4-b]pyrazin-5-yl]amino]butan-1-ol
Show/Hide
|
C18H22N6O
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
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CP0528846
|
N-[[5-(4-fluoro-2-methoxyphenyl)pyridin-3-yl]methyl]cyclopropanecarboxamide
Show/Hide
|
C17H17FN2O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0032962
|
2-(oxan-4-yl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C22H21F3N2O4
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0449604
|
2-[2-(5-fluoropyrimidin-2-yl)ethyl]-N-[[4-fluoro-3-(trifluoromethyl)phenyl]methyl]-3-oxo-1H-isoindole-1-carboxamide
Show/Hide
|
C23H17F5N4O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0500330
|
2-(4-cyanocyclohexyl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
Show/Hide
|
C24H22F3N3O3
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0208586
|
2-[(3S)-3-(3,4-dichlorophenyl)azepan-3-yl]ethanol
Show/Hide
|
C14H19Cl2NO
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0239553
|
2-[(3S)-3-(3,4-dichlorophenyl)piperidin-3-yl]ethanol
Show/Hide
|
C13H17Cl2NO
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0262846
|
2-[(3R)-3-(1-benzofuran-2-yl)piperidin-3-yl]ethanol
Show/Hide
|
C15H19NO2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0285757
|
2-[(3R)-3-(3,4-dichlorophenyl)piperidin-3-yl]ethanol
Show/Hide
|
C13H17Cl2NO
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0285758
|
2-[(3R)-3-(3,4-dichlorophenyl)azepan-3-yl]ethanol
Show/Hide
|
C14H19Cl2NO
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0334040
|
3-(3-chlorophenyl)-2,3,4,7-tetrahydro-1H-azepine
Show/Hide
|
C12H14ClN
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0121871
|
(4-cyclobutylpiperazin-1-yl)-[7-(oxan-4-yl)-7-azaspiro[3.5]nonan-2-yl]methanone
Show/Hide
|
C22H37N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0225036
|
[(2S)-6-(oxan-4-yl)-6-azaspiro[2.5]octan-2-yl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C20H35N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0422084
|
(4-cyclobutylpiperazin-1-yl)-(7-phenyl-7-azaspiro[3.5]nonan-2-yl)methanone
Show/Hide
|
C23H33N3O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0422088
|
[6-(oxan-4-yl)-6-azaspiro[2.5]octan-2-yl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C20H35N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0422092
|
(4-cyclobutyl-1,4-diazepan-1-yl)-(8-propan-2-ylsulfonyl-2,8-diazaspiro[4.5]decan-2-yl)methanone
Show/Hide
|
C21H38N4O3S
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0422118
|
[8-(benzenesulfonyl)-2,8-diazaspiro[4.5]decan-2-yl]-(4-cyclobutyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C24H36N4O3S
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0422251
|
(4-cyclobutylpiperazin-1-yl)-[6-(oxan-4-yl)-6-azaspiro[2.5]octan-2-yl]methanone
Show/Hide
|
C21H35N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0458806
|
1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl-[7-(oxan-4-yl)-7-azaspiro[3.5]nonan-2-yl]methanone
Show/Hide
|
C22H37N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0467077
|
[7-(benzenesulfonyl)-2,7-diazaspiro[4.5]decan-2-yl]-(4-cyclobutyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C24H36N4O3S
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0467078
|
(4-cyclopropylpiperazin-1-yl)-[6-(oxan-4-yl)-6-azaspiro[2.5]octan-2-yl]methanone
Show/Hide
|
C20H33N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0467079
|
[2-(4-cyclobutyl-1,4-diazepane-1-carbonyl)-2,8-diazaspiro[4.5]decan-8-yl]-phenylmethanone
Show/Hide
|
C25H36N4O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0469125
|
(4-cyclopentylpiperazin-1-yl)-[6-(oxan-4-yl)-6-azaspiro[2.5]octan-2-yl]methanone
Show/Hide
|
C22H37N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0473254
|
[7-(oxan-4-yl)-7-azaspiro[3.5]nonan-2-yl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C21H37N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0478593
|
(7-benzoyl-7-azaspiro[3.5]nonan-2-yl)-(4-cyclobutylpiperazin-1-yl)methanone
Show/Hide
|
C24H33N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0487028
|
(7-benzoyl-7-azaspiro[3.5]nonan-2-yl)-(4-propan-2-yl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C24H35N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0487070
|
[2-(4-cyclobutylpiperazine-1-carbonyl)-2,8-diazaspiro[4.5]decan-8-yl]-phenylmethanone
Show/Hide
|
C24H34N4O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0487072
|
[9-(oxan-4-yl)-2,9-diazaspiro[4.5]decan-2-yl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C21H38N4O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0487073
|
(4-cyclobutyl-1,4-diazepan-1-yl)-[9-(oxan-4-yl)-2,9-diazaspiro[4.5]decan-2-yl]methanone
Show/Hide
|
C23H40N4O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0489300
|
[(2R)-6-(oxan-4-yl)-6-azaspiro[2.5]octan-2-yl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C20H35N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0489302
|
6-azaspiro[2.5]octan-2-yl-(4-cyclohexylpiperazin-1-yl)methanone
Show/Hide
|
C18H31N3O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0489305
|
[8-(oxan-4-yl)-2,8-diazaspiro[4.5]decan-2-yl]-(4-propan-2-ylpiperazin-1-yl)methanone
Show/Hide
|
C21H38N4O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0555257
|
(4-cyclohexylpiperazin-1-yl)-[6-(oxan-4-yl)-6-azaspiro[2.5]octan-2-yl]methanone
Show/Hide
|
C23H39N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0566246
|
(4-cyclobutylpiperazin-1-yl)-(7-methylsulfonyl-7-azaspiro[3.5]nonan-2-yl)methanone
Show/Hide
|
C18H31N3O3S
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0046515
|
1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]-2-(methylamino)ethanone
Show/Hide
|
C24H28ClN9O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0059945
|
1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-5-methylpyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C22H23ClN8O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0131631
|
(2S)-2-amino-1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]propan-1-one
Show/Hide
|
C24H28ClN9O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0133963
|
2-amino-1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]ethanone
Show/Hide
|
C23H26ClN9O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0148255
|
1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3-methoxyphenyl]piperazin-1-yl]ethanone
Show/Hide
|
C24H24ClN7O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0350256
|
(2R)-2-amino-1-[4-[4-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-3,5-dimethylpyrazol-1-yl]piperidin-1-yl]propan-1-one
Show/Hide
|
C24H28ClN9O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0510238
|
5-chloro-4-imidazo[1,2-a]pyridin-3-yl-N-(5-methyl-1-piperidin-4-ylpyrazol-4-yl)pyrimidin-2-amine
Show/Hide
|
C20H21ClN8
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0349042
|
[5-(3-ethyl-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C18H18N2O2S2
|
1
|
| 1 |
IC50 = 36000 nM
|
|
|
|
CP0455316
|
(2-aminopyridin-4-yl)-[9-[(2,2-dimethylchromen-8-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
|
C27H34N4O2
|
1
|
| 1 |
IC50 = 38018.94 nM
|
|
|
|
CP0860701
|
4-(3,5-difluorobenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C26H31F2N3O5
|
1
|
| 1 |
IC50 = 39810.72 nM
|
|
|
|
CP0146499
|
2-fluoro-N-[3-fluoro-4-[5-(4-morpholin-4-ylbutylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
|
C23H25F2N5O3
|
1
|
| 1 |
IC50 = 39810.72 nM
|
|
|
|
CP0461431
|
8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-6-carboxylic acid
Show/Hide
|
C31H40N4O3
|
1
|
| 1 |
IC50 = 39810.72 nM
|
|
|
|
CP0564633
|
N-[4-[1-[2-(2,4-difluorophenyl)-2-oxoethyl]-4-methyl-2,5-dioxoimidazolidin-4-yl]phenyl]methanesulfonamide
Show/Hide
|
C19H17F2N3O5S
|
1
|
| 1 |
IC50 = 39810.72 nM
|
|
|
|
CP0485838
|
N'-[7-[6-(dimethylamino)pyridin-3-yl]pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine
Show/Hide
|
C18H23N7
|
1
|
| 1 |
IC50 = 39810.72 nM
|
|
|
|
CP0556851
|
7-[6-(dimethylamino)pyridin-3-yl]-N-[[(3S)-piperidin-3-yl]methyl]quinolin-5-amine
Show/Hide
|
C22H27N5
|
1
|
| 1 |
IC50 = 39810.72 nM
|
|
|
|
CP0540590
|
(4aR,6S,8aS)-6-methyl-8a-thiophen-3-yl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
|
C12H16N2OS2
|
1
|
| 1 |
IC50 = 39900 nM
|
|
|
|
CP0422582
|
5-[4-(hydroxymethyl)pyridin-3-yl]-N-(oxan-4-ylmethyl)-1H-indazole-3-carboxamide
Show/Hide
|
C20H22N4O3
|
1
|
| 1 |
IC50 = 41300 nM
|
|
|
|
CP0574856
|
(2S)-6-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-8-chloro-2-methyl-12-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,10-tetraene-11-carboxylic acid
Show/Hide
|
C20H22ClN3O4
|
1
|
| 1 |
IC50 = 42000 nM
|
|
|
|
CP0238478
|
US9315520, 10
Show/Hide
|
C17H20N6O3S2
|
1
|
| 1 |
IC50 = 43000 nM
|
|
|
|
CP0388409
|
(5-aminopyridin-2-yl)-[9-[(2,2-dimethyl-3H-1-benzofuran-7-yl)methyl]-3,9-diazaspiro[5.5]undecan-3-yl]methanone
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
IC50 = 43651.58 nM
|
|
|
|
CP0384459
|
[5-[3-ethyl-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C16H18N4O2S2
|
1
|
| 1 |
IC50 = 47000 nM
|
|
|
|
CP0570870
|
5-[4-(methoxymethyl)pyridin-3-yl]-N-(oxan-4-ylmethyl)-1H-indazole-3-carboxamide
Show/Hide
|
C21H24N4O3
|
1
|
| 1 |
IC50 = 47100 nM
|
|
|
|
CP0034173
|
7-[(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-methylquinolin-2-one
Show/Hide
|
C19H24FN3O
|
1
|
| 1 |
IC50 = 49000 nM
|
|
|
|
CP0487581
|
N-(oxan-4-ylmethyl)-5-pyridin-3-yl-1H-indazole-3-carboxamide
Show/Hide
|
C19H20N4O2
|
1
|
| 1 |
IC50 = 49300 nM
|
|
|
|
CP0681609
|
4-(4-fluoro-benzoyl)-1-[4-(3-piperidin-1-yl-propoxy)-phenyl]-piperazin-2-one formic acid
Show/Hide
|
C26H32FN3O5
|
1
|
| 1 |
IC50 = 50118.72 nM
|
|
|
|
CP0896096
|
1-(4-(3-(azepan-1-yl)propoxy)phenyl)-4-(2,4-difluorobenzoyl)piperazin-2-one formic acid
Show/Hide
|
C27H33F2N3O5
|
1
|
| 1 |
IC50 = 50118.72 nM
|
|
|
|
CP0189448
|
2-[[(3R,4R)-3-aminooxan-4-yl]amino]-4-(4-methoxyanilino)pyrimidine-5-carboxamide
Show/Hide
|
C17H22N6O3
|
1
|
| 1 |
IC50 > 50118.72 nM
|
|
|
|
CP0005166
|
BMS-354825
Show/Hide
|
C22H26ClN7O2S
|
1
|
| 1 |
IC50 = 50118.72 nM
|
|
|
|
CP0464411
|
3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]-6-ethylquinolin-2-yl]propanoic acid
Show/Hide
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C35H48N4O3
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1
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| 1 |
IC50 = 50118.72 nM
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CP0526070
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3-[2-(2,4-difluorophenyl)-2-oxoethyl]-5-methyl-5-[4-(2-oxo-1,3-oxazolidin-3-yl)phenyl]imidazolidine-2,4-dione
Show/Hide
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C21H17F2N3O5
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1
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| 1 |
IC50 > 50118.72 nM
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CP0560814
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3-[2-(2,4-difluorophenyl)-2-oxoethyl]-5-methyl-5-phenylimidazolidine-2,4-dione
Show/Hide
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C18H14F2N2O3
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1
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| 1 |
IC50 > 50118.72 nM
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CP0564632
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3-[2-(2,4-difluorophenyl)-2-oxoethyl]-5-methyl-5-(4-methylsulfonylphenyl)imidazolidine-2,4-dione
Show/Hide
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C19H16F2N2O5S
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1
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| 1 |
IC50 > 50118.72 nM
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CP0564634
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4-[1-[2-(3,5-difluoropyridin-2-yl)-2-oxoethyl]-4-methyl-2,5-dioxoimidazolidin-4-yl]benzonitrile
Show/Hide
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C18H12F2N4O3
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1
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| 1 |
IC50 > 50118.72 nM
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CP0149809
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7-[6-(dimethylamino)pyridin-3-yl]-N-[[(2R)-morpholin-2-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C19H23N7O
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1
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| 1 |
IC50 > 50118.72 nM
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CP0213834
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7-[6-(dimethylamino)pyridin-3-yl]-N-[[(3S)-piperidin-3-yl]methyl]-1,6-naphthyridin-5-amine
Show/Hide
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C21H26N6
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1
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| 1 |
IC50 > 50118.72 nM
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CP0213838
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7-(1-methylpyrazol-4-yl)-N-[[(3S)-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C17H21N7
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1
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| 1 |
IC50 > 50118.72 nM
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CP0255250
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4-[5-[[(3S)-piperidin-3-yl]methylamino]pyrido[3,4-b]pyrazin-7-yl]piperazin-2-one
Show/Hide
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C17H23N7O
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1
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| 1 |
IC50 = 50118.72 nM
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CP0255255
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7-(1-methylpyrazol-4-yl)-N-[[(2S)-morpholin-2-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C16H19N7O
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1
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| 1 |
IC50 > 50118.72 nM
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CP0352190
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7-piperazin-1-yl-N-[[(3S)-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C17H25N7
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1
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| 1 |
IC50 > 50118.72 nM
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CP0352191
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N-[[(3S)-piperidin-3-yl]methyl]-7-(1H-pyrazol-4-yl)pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C16H19N7
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1
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| 1 |
IC50 > 50118.72 nM
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CP0463552
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5-[(5,5-difluoropiperidin-3-yl)methoxy]-7-(1-methylpyrazol-4-yl)pyrido[3,4-b]pyrazine
Show/Hide
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C17H18F2N6O
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1
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| 1 |
IC50 > 50118.72 nM
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CP0485839
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7-[6-(dimethylamino)pyridin-3-yl]-N-(2,2,2-trifluoroethyl)pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C16H15F3N6
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1
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| 1 |
IC50 > 50118.72 nM
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CP0485840
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N-[[(2S)-1-methylpiperazin-2-yl]methyl]-7-(1-methylpyrazol-4-yl)pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C17H22N8
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1
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| 1 |
IC50 > 50118.72 nM
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CP0485841
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3-[[7-[6-(dimethylamino)pyridin-3-yl]pyrido[3,4-b]pyrazin-5-yl]amino]propanamide
Show/Hide
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C17H19N7O
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1
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| 1 |
IC50 > 50118.72 nM
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CP0485842
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7-[6-(dimethylamino)pyridin-3-yl]-N-[[(2S)-morpholin-2-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C19H23N7O
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1
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| 1 |
IC50 > 50118.72 nM
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CP0485844
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7-[6-(dimethylamino)pyridin-3-yl]-N-[[(2S)-1-methylpiperazin-2-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C20H26N8
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1
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| 1 |
IC50 > 50118.72 nM
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CP0530524
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N-[(5,5-difluoropiperidin-3-yl)methyl]-7-[6-(dimethylamino)pyridin-3-yl]pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C20H23F2N7
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1
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| 1 |
IC50 > 50118.72 nM
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CP0530877
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7-(1-methylpyrazol-4-yl)-5-[[(3S)-piperidin-3-yl]methoxy]pyrido[3,4-b]pyrazine
Show/Hide
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C17H20N6O
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1
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| 1 |
IC50 > 50118.72 nM
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CP0531984
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N-[(5,5-difluoropiperidin-3-yl)methyl]-7-(1-methylpyrazol-4-yl)pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C17H19F2N7
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1
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| 1 |
IC50 > 50118.72 nM
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CP0550624
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N-[[(3S)-piperidin-3-yl]methyl]-7-(1H-pyrazol-5-yl)pyrido[3,4-b]pyrazin-5-amine
Show/Hide
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C16H19N7
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1
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| 1 |
IC50 > 50118.72 nM
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CP0559861
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5-[[(2S)-1-methylpiperazin-2-yl]methoxy]-7-(1-methylpyrazol-4-yl)pyrido[3,4-b]pyrazine
Show/Hide
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C17H21N7O
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1
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| 1 |
IC50 > 50118.72 nM
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CP0528276
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(5-naphthalen-2-ylsulfonyl-1,3-thiazol-2-yl)methanamine
Show/Hide
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C14H12N2O2S2
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1
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| 1 |
IC50 = 51000 nM
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CP0361400
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(4aR,6S,8aS)-6-methyl-8a-[2-(trifluoromethyl)phenyl]-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
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C15H17F3N2OS
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1
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| 1 |
IC50 = 55400 nM
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CP0890879
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4-benzoyl-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one hydrochloride
Show/Hide
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C25H32ClN3O3
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1
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| 1 |
IC50 = 63095.73 nM
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CP0124168
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2-fluoro-N-[4-[5-(4-morpholin-4-ylbutylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C23H26FN5O3
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1
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| 1 |
IC50 = 63095.73 nM
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CP0432094
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2-fluoro-N-[3-methoxy-4-[5-(4-morpholin-4-ylbutylamino)-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C24H28FN5O4
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1
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| 1 |
IC50 > 63095.73 nM
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CP0450474
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N-[4-[5-[3-(4,4-difluoropiperidin-1-yl)propylamino]-1,3,4-oxadiazol-2-yl]phenyl]-2-fluorobenzamide
Show/Hide
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C23H24F3N5O2
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1
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| 1 |
IC50 > 63095.73 nM
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CP0513763
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2-fluoro-N-[4-[5-[3-(4-methylpiperazin-1-yl)propylamino]-1,3,4-oxadiazol-2-yl]phenyl]benzamide
Show/Hide
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C23H27FN6O2
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1
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| 1 |
IC50 = 63095.73 nM
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CP0002230
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4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
Show/Hide
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C28H22F3N7O
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1
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| 1 |
IC50 = 63095.73 nM
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CP0013112
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(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate
Show/Hide
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C27H37N3O7S
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1
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| 1 |
IC50 = 63095.73 nM
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CP0461430
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8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-4-carboxylic acid
Show/Hide
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C31H40N4O3
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1
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| 1 |
IC50 > 63095.73 nM
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CP0468326
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8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinoline-5-carbonitrile
Show/Hide
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C31H39N5O
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1
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| 1 |
IC50 > 63095.73 nM
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CP0469081
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(E)-3-[8-[4-[2-[4-[3-(azepan-1-yl)propoxy]phenyl]ethyl]piperazin-1-yl]quinolin-2-yl]prop-2-enoic acid
Show/Hide
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C33H42N4O3
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1
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| 1 |
IC50 > 63095.73 nM
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CP0559457
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[5-[3-fluoro-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
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C14H13FN4O2S2
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1
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| 1 |
IC50 = 66000 nM
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CP0356374
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1-[6-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazin-1-yl]ethanone
Show/Hide
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C30H42FN5O3
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1
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| 1 |
IC50 = 69000 nM
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CP0000847
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(2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11(16),12,14-tetraene-4,7-dione
Show/Hide
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C22H19N3O4
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1
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| 1 |
IC50 = 79432.82 nM
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CP0097509
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(4aR,6S,8aS)-8a-(2-methoxyphenyl)-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
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C15H20N2O2S
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1
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| 1 |
IC50 = 85600 nM
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CP0097510
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(4aR,6S,8aS)-6-methyl-8a-phenyl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
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C14H18N2OS
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1
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| 1 |
IC50 = 85700 nM
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CP0574855
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(2S)-6-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-2-methyl-12-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13),10-tetraene-11-carboxylic acid
Show/Hide
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C20H23N3O4
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1
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| 1 |
IC50 = 90000 nM
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CP0088771
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7-(2-fluorophenyl)-3-(4-methoxyphenyl)thieno[3,2-d]pyrimidin-4-one
Show/Hide
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C19H13FN2O2S
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1
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| 1 |
IC50 > 100000 nM
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CP0644033
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4-{[(3S,4R)-1-(5-Cyanopyridin-2-yl)-3-fluoropiperidin-4-yl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
Show/Hide
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C19H18FN7O
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1
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| 1 |
IC50 > 100000 nM
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CP0659782
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4-{[1-(6-Cyanopyridazin-3-yl)piperidin-4-yl]amino}-1Hpyrrolo[2,3-b]pyridine-5-carboxamide
Show/Hide
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C18H18N8O
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1
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| 1 |
IC50 > 100000 nM
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CP0684740
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4-{[(3R,4S)-1-(5-Cyanopyridin-2-yl)-3-fluoropiperidin-4-yl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
Show/Hide
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C19H18FN7O
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1
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| 1 |
IC50 > 100000 nM
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CP0944168
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4-{[1-(5-Cyanopyrazin-2-yl)piperidin-4-yl]amino}-1Hpyrrolo[2,3-b]pyridine-5-carboxamide
Show/Hide
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C18H18N8O
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1
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| 1 |
IC50 > 100000 nM
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CP0390399
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4-[[(1R,2R,3aR,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-5-hydroxy-5,7a-dimethyl-2,3,3a,4,6,7-hexahydro-1H-inden-1-yl]oxy]benzonitrile
Show/Hide
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C23H33N3O2
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1
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| 1 |
IC50 > 100000 nM
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CP0390400
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4-[[(1R,2R,3R,5R)-3-[(3R)-3-aminopiperidin-1-yl]-6-oxo-2-bicyclo[3.2.0]heptanyl]oxy]benzonitrile
Show/Hide
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C19H23N3O2
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1
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| 1 |
IC50 > 100000 nM
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CP0538675
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4-[[(1R,2R,3aR,7aS)-2-[(3R)-3-aminopiperidin-1-yl]-7a-methyl-5-oxo-2,3,3a,4,6,7-hexahydro-1H-inden-1-yl]oxy]benzonitrile
Show/Hide
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C22H29N3O2
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1
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| 1 |
IC50 > 100000 nM
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CP0149411
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(4aR,6S,8aR)-6-methyl-8a-thiophen-2-yl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
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C12H16N2OS2
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1
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| 1 |
IC50 > 100000 nM
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CP0179938
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(4aR,6S,8aS)-8a-(3-fluoropyridin-2-yl)-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
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C13H16FN3OS
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1
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| 1 |
IC50 > 100000 nM
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CP0189453
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(4aR,6S,8aR)-6-methyl-8a-(1,3-thiazol-2-yl)-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
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C11H15N3OS2
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1
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| 1 |
IC50 > 100000 nM
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CP0101306
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N-hydroxy-3-[methyl-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]-1-(2-methylpropanoyl)azetidine-3-carboxamide
Show/Hide
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C26H30N4O6S
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1
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| 1 |
IC50 > 100000 nM
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CP0149466
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N-hydroxy-1-(3-methylbutanoyl)-3-[methyl-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]sulfonylamino]azetidine-3-carboxamide
Show/Hide
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C27H32N4O6S
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1
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| 1 |
IC50 > 100000 nM
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CP0020443
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4-[[1-(4-cyanophenyl)piperidin-4-yl]amino]-6-[(2-methylpyrimidin-4-yl)amino]pyridine-3-carboxamide
Show/Hide
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C23H24N8O
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1
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| 1 |
IC50 > 100000 nM
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CP0157772
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4-[[(3S,4R)-1-(5-cyanopyridin-2-yl)-3-fluoropiperidin-4-yl]amino]-6-[(2-methylpyrimidin-4-yl)amino]pyridine-3-carboxamide
Show/Hide
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C22H22FN9O
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1
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| 1 |
IC50 > 100000 nM
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CP0032233
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5-[5-(hydroxymethyl)pyridin-3-yl]-N-(oxan-4-ylmethyl)-1H-indazole-3-carboxamide
Show/Hide
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C20H22N4O3
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1
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| 1 |
IC50 > 100000 nM
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CP0845127
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4-(2,4-difluorobenzoyl)-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one
Show/Hide
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C24H27F2N3O3
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1
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| 1 |
IC50 < 15848.93 nM
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CP0845136
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4-(2-oxo-1-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)piperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
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C26H30N4O5
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1
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| 1 |
IC50 < 15848.93 nM
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CP0495731
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4-(4-fluoro-benzoyl)-1-[4-(3-piperidin-1-yl-propoxy)-phenyl]-piperazin-2-one formic acid
Show/Hide
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C25H30FN3O3
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1
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| 1 |
IC50 < 31622.78 nM
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CP0854415
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1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-fluorobenzoyl)piperazin-2-one hydrochloride
Show/Hide
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C26H31ClFN3O3
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1
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| 1 |
IC50 < 31622.78 nM
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CP0845124
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4-(1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C27H32N4O5
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1
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| 1 |
IC50 < 63095.73 nM
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CP0845129
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4-isonicotinoyl-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
Show/Hide
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C25H32N4O5
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1
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| 1 |
IC50 < 63095.73 nM
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CP0845131
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4-(1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C29H34N4O5
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1
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| 1 |
IC50 < 63095.73 nM
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CP0845133
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(S)-4-(1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C27H32N4O5
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1
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| 1 |
IC50 < 63095.73 nM
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CP0845135
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1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(3-(methylsulfonyl)benzoyl)piperazin-2-one formic acid
Show/Hide
|
C29H37N3O7S
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1
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| 1 |
IC50 < 63095.73 nM
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CP0860700
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(R)-4-(1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid
Show/Hide
|
C27H32N4O5
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1
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| 1 |
IC50 < 63095.73 nM
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CP0860702
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4-(4-(methylsulfonyl)benzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one
Show/Hide
|
C26H33N3O5S
|
1
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| 1 |
IC50 < 63095.73 nM
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CP0860704
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1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-4-pivaloylpiperazin-2-one hydrochloride
Show/Hide
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C23H36ClN3O3
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1
|
| 1 |
IC50 < 63095.73 nM
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CP0872588
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4-(4-(azetidine-1-carbonyl)benzoyl)-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
Show/Hide
|
C31H38N4O6
|
1
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| 1 |
IC50 < 63095.73 nM
|
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CP0873040
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1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-methylbenzoyl)piperazin-2-one hydrochloride
Show/Hide
|
C27H34ClN3O3
|
1
|
| 1 |
IC50 < 63095.73 nM
|
|
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CP0896097
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1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-4-(pyrazolo[1,5-a]pyrimidine-3-carbonyl)piperazin-2-one formic acid
Show/Hide
|
C26H32N6O5
|
1
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| 1 |
IC50 < 63095.73 nM
|
|
|
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CP0900122
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4-(2,4-difluorobenzoyl)-1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
Show/Hide
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C26H31F2N3O5
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1
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| 1 |
IC50 < 63095.73 nM
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CP0906031
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4-(4-(azetidine-1-carbonyl)benzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
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C30H38N4O6
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1
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| 1 |
IC50 < 63095.73 nM
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CP0915877
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4-(3,5-difluorobenzoyl)-1-(4-(1-isopropylpiperidin-4-yloxy)phenyl)piperazin-2-one formic acid
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C26H31F2N3O5
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1
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| 1 |
IC50 < 63095.73 nM
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CP0915879
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1-(4-(1-cyclopentylpiperidin-4-yloxy)phenyl)-4-(4-(methylsulfonyl)benzoyl)piperazin-2-one formic acid
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C29H37N3O7S
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1
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| 1 |
IC50 < 63095.73 nM
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CP0915880
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1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(3,5-difluorobenzoyl)piperazin-2-one formic acid
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C27H31F2N3O5
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1
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| 1 |
IC50 < 63095.73 nM
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CP0915881
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4-(2,4-difluorobenzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
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C26H31F2N3O5
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1
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| 1 |
IC50 < 63095.73 nM
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CP0916136
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1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(2,4-difluorobenzoyl)piperazin-2-one formic acid
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C27H31F2N3O5
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1
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| 1 |
IC50 < 63095.73 nM
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CP0918636
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4-benzoyl-1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)piperazin-2-one hydrochloride
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C26H32ClN3O3
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1
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| 1 |
IC50 < 63095.73 nM
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CP0920179
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4-(3-(methylsulfonyl)benzoyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid
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C27H35N3O7S
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1
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| 1 |
IC50 < 63095.73 nM
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CP0939742
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1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-4-(4-(methylsulfonyl)benzoyl)piperazin-2-one formic acid
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C28H35N3O7S
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1
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| 1 |
IC50 < 63095.73 nM
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