General Information of the Compound
Compound ID
CP0471035
Compound Name
3-benzoyl-N-[[5-(2-methylpropyl)-1-phenylpyrazol-3-yl]methyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
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Structure
Formula
C27H30N4O2
Molecular Weight
442.563
Canonical SMILES
CC(C)Cc1cc(CNC(=O)C2C3CN(CC23)C(=O)c2ccccc2)nn1-c1ccccc1
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InChI
InChI=1S/C27H30N4O2/c1-18(2)13-22-14-20(29-31(22)21-11-7-4-8-12-21)15-28-26(32)25-23-16-30(17-24(23)25)27(33)19-9-5-3-6-10-19/h3-12,14,18,23-25H,13,15-17H2,1-2H3,(H,28,32)
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InChIKey
AJDSKTXYDMITDW-UHFFFAOYSA-N
Physicochemical Property
logP
3.7052
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
67.23
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 86292938
ChEMBL ID
CHEMBL4463242
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 15000 nM
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