Brief Information of the Compound and Protein
Compound Name
4-[2-[4-[[1-[[6-(trifluoromethyl)pyridin-3-yl]methyl]benzimidazol-2-yl]amino]piperidin-1-yl]ethyl]benzonitrile
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Canonical SMILES
FC(F)(F)c1ccc(Cn2c(NC3CCN(CCc4ccc(cc4)C#N)CC3)nc3ccccc23)cn1
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Compound Formula C28H27F3N6
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 970 nM
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