Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CAS_52-53-9
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 PubChem ID
CID: 2520
SID: 14784349
Canonical SMILES
COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC
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Compound Formula C27H38N2O4
Compound Structure
Protein Name
 Protein Info 
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Potassium channels
>
Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 141.25 nM
   TI
   LI
   LO
   TS
2
IC50 = 143 nM
   TI
   LI
   LO
   TS
3
IC50 = 530 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 143 nM
   TI
   LI
   LO
   TS
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 144.54 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM
2 IC50 = 141.25 nM
3 IC50 = 400 nM
4 IC50 = 3100 nM