Compound ID |
Compound Name |
Compound Formula |
CP0383206
|
4-(4-fluorophenyl)-N-[8-methyl-3-(pyrrolidin-1-ylmethyl)quinolin-7-yl]benzamide
Show/Hide
|
C28H26FN3O
|
2
|
1 |
IC50 = 1 nM
|
|
|
2 |
IC50 = 1.7 nM
|
|
|
CP0421013
|
4-butoxy-N-[8-methyl-3-(pyrrolidin-1-ylmethyl)quinolin-7-yl]benzamide
Show/Hide
|
C26H31N3O2
|
1
|
1 |
IC50 = 1.2 nM
|
|
|
CP0383012
|
4-(cyclopropylmethoxy)-N-[8-methyl-3-(pyrrolidin-1-ylmethyl)quinolin-7-yl]benzamide
Show/Hide
|
C26H29N3O2
|
1
|
1 |
IC50 = 1.6 nM
|
|
|
CP0383034
|
4-(cyclopropylmethoxy)-N-[8-methyl-3-[(1R)-1-pyrrolidin-1-ylethyl]quinolin-7-yl]benzamide
Show/Hide
|
C27H31N3O2
|
1
|
1 |
IC50 = 1.9 nM
|
|
|
CP0475742
|
4-(2-cyclopropylethoxy)-N-[8-methyl-3-(pyrrolidin-1-ylmethyl)quinolin-7-yl]benzamide
Show/Hide
|
C27H31N3O2
|
1
|
1 |
IC50 = 2 nM
|
|
|
CP0498841
|
4-(4-chlorophenyl)-N-[6-(pyrrolidin-1-ylmethyl)-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C28H27ClN2O
|
1
|
1 |
IC50 = 2.2 nM
|
|
|
CP0526610
|
4-(4-methylphenyl)-N-[6-(pyrrolidin-1-ylmethyl)-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C29H30N2O
|
1
|
1 |
IC50 = 2.4 nM
|
|
|
CP0526881
|
N-[3-[(1R)-1-(2-acetamidoethylamino)ethyl]-8-methylquinolin-7-yl]-4-(cyclopropylmethoxy)benzamide
Show/Hide
|
C27H32N4O3
|
1
|
1 |
IC50 = 2.4 nM
|
|
|
CP0472693
|
4-(4-chlorophenyl)-N-[6-(piperidin-1-ylmethyl)-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C29H29ClN2O
|
1
|
1 |
IC50 = 2.5 nM
|
|
|
CP0425471
|
4-(4-chlorophenyl)-N-[6-[(dimethylamino)methyl]-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C26H25ClN2O
|
1
|
1 |
IC50 = 2.7 nM
|
|
|
CP0515596
|
4-(cyclopropylmethoxy)-N-[3-[1-[(2-hydroxy-2-methylpropyl)amino]ethyl]-8-methylquinolin-7-yl]benzamide
Show/Hide
|
C27H33N3O3
|
1
|
1 |
IC50 = 2.7 nM
|
|
|
CP0489108
|
N-[3-[1-(2-acetamidoethylamino)ethyl]-8-methylquinolin-7-yl]-4-(cyclopropylmethoxy)benzamide
Show/Hide
|
C27H32N4O3
|
1
|
1 |
IC50 = 3.4 nM
|
|
|
CP0498842
|
4-(4-methoxyphenyl)-N-[6-(pyrrolidin-1-ylmethyl)-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C29H30N2O2
|
1
|
1 |
IC50 = 3.7 nM
|
|
|
CP0428326
|
4-(4-fluorophenyl)-N-[6-(pyrrolidin-1-ylmethyl)-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C28H27FN2O
|
2
|
1 |
IC50 = 4.1 nM
|
|
|
2 |
IC50 = 11 nM
|
|
|
CP0494822
|
4-(cyclopropylmethoxy)-N-[8-methyl-3-(1-pyrrolidin-1-ylethyl)quinolin-7-yl]benzamide
Show/Hide
|
C27H31N3O2
|
1
|
1 |
IC50 = 4.2 nM
|
|
|
CP0426176
|
4-(4-chlorophenyl)-N-[6-[(4-methylpiperazin-1-yl)methyl]-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C29H30ClN3O
|
1
|
1 |
IC50 = 5.3 nM
|
|
|
CP0416008
|
N-[3-[1-(azepan-1-yl)ethyl]-8-methylquinolin-7-yl]-4-(cyclopropylmethoxy)benzamide
Show/Hide
|
C29H35N3O2
|
1
|
1 |
IC50 = 5.6 nM
|
|
|
CP0459932
|
4-(4-chlorophenyl)-N-[6-[[methyl(propanoyl)amino]methyl]-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C28H27ClN2O2
|
1
|
1 |
IC50 = 6.2 nM
|
|
|
CP0407716
|
N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-2-[4-(trifluoromethoxy)phenoxy]acetamide
Show/Hide
|
C20H18F3N3O3
|
1
|
1 |
IC50 = 6.3 nM
|
|
|
CP0475139
|
4-[4-(4-chlorophenyl)piperidin-1-yl]-1-(3-ethylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-7-yl)butan-1-one
Show/Hide
|
C27H35ClN2O3S
|
1
|
1 |
IC50 = 6.4 nM
|
|
|
CP0383014
|
4-(cyclopropylmethoxy)-N-[8-methyl-3-[(2-methylpyrrolidin-1-yl)methyl]quinolin-7-yl]benzamide
Show/Hide
|
C27H31N3O2
|
1
|
1 |
IC50 = 6.7 nM
|
|
|
CP0416006
|
4-(2-methylpropoxy)-N-[8-methyl-3-(pyrrolidin-1-ylmethyl)quinolin-7-yl]benzamide
Show/Hide
|
C26H31N3O2
|
1
|
1 |
IC50 = 6.7 nM
|
|
|
CP0475339
|
4-[4-(4-chlorophenyl)piperidin-1-yl]-1-[3-(cyclopropanecarbonyl)-1,2,4,5-tetrahydro-3-benzazepin-7-yl]butan-1-one
Show/Hide
|
C29H35ClN2O2
|
1
|
1 |
IC50 = 7.3 nM
|
|
|
CP0452187
|
1-(3-butanoyl-1,2,4,5-tetrahydro-3-benzazepin-7-yl)-4-[4-(4-chlorophenyl)piperidin-1-yl]butan-1-one
Show/Hide
|
C29H37ClN2O2
|
1
|
1 |
IC50 = 7.5 nM
|
|
|
CP0407728
|
4-[(5-chlorothiophen-3-yl)methoxy]-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyridin-2-one
Show/Hide
|
C21H18ClN3O2S
|
1
|
1 |
IC50 = 7.5 nM
|
|
|
CP0407714
|
N-(2,3-dimethylimidazo[1,2-a]pyridin-6-yl)-2-[4-(trifluoromethoxy)phenoxy]acetamide
Show/Hide
|
C18H16F3N3O3
|
1
|
1 |
IC50 = 7.8 nM
|
|
|
CP0421009
|
4-(cyclopropylmethoxy)-N-[8-methyl-3-[(1S)-1-pyrrolidin-1-ylethyl]quinolin-7-yl]benzamide
Show/Hide
|
C27H31N3O2
|
1
|
1 |
IC50 = 8 nM
|
|
|
CP0383008
|
4-(cyclopropylmethoxy)-N-[8-methyl-3-(1-piperidin-1-ylethyl)quinolin-7-yl]benzamide
Show/Hide
|
C28H33N3O2
|
1
|
1 |
IC50 = 8.3 nM
|
|
|
CP0526882
|
4-(cyclopropylmethoxy)-N-[8-methyl-3-(2-pyrrolidin-1-ylpropan-2-yl)quinolin-7-yl]benzamide
Show/Hide
|
C28H33N3O2
|
1
|
1 |
IC50 = 8.3 nM
|
|
|
CP0400414
|
4-[4-(4-chlorophenyl)piperidin-1-yl]-1-(3-propanoyl-1,2,4,5-tetrahydro-3-benzazepin-7-yl)butan-1-one
Show/Hide
|
C28H35ClN2O2
|
1
|
1 |
IC50 = 8.4 nM
|
|
|
CP0903416
|
4'-Chloro-N-[6-(methylamino)methyl]-7,8-dihydro-2-naphthalenyl][1,1'-biphenyl]-4-carboxamide 2,2,2-trifluoroacetate
Show/Hide
|
C27H24ClF3N2O3
|
1
|
1 |
IC50 = 8.5 nM
|
|
|
CP0387991
|
4-[4-(4-chlorophenyl)piperidin-1-yl]-1-(3-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-7-yl)butan-1-one
Show/Hide
|
C26H33ClN2O3S
|
1
|
1 |
IC50 = 8.5 nM
|
|
|
CP0452306
|
4-[(4-bromophenyl)methoxy]-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyridin-2-one
Show/Hide
|
C23H20BrN3O2
|
1
|
1 |
IC50 = 9.3 nM
|
|
|
CP0490517
|
4-[(5-chlorothiophen-3-yl)methoxy]-1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C21H18ClN3O2S
|
1
|
1 |
IC50 = 9.3 nM
|
|
|
CP0392050
|
7-[4-[4-(4-chlorophenyl)piperidin-1-yl]butanoyl]-N-ethyl-1,2,4,5-tetrahydro-3-benzazepine-3-carboxamide
Show/Hide
|
C28H36ClN3O2
|
1
|
1 |
IC50 = 11 nM
|
|
|
CP0400412
|
1-(2-acetyl-3,4-dihydro-1H-isoquinolin-7-yl)-4-[4-(4-chlorophenyl)piperidin-1-yl]butan-1-one
Show/Hide
|
C26H31ClN2O2
|
1
|
1 |
IC50 = 11 nM
|
|
|
CP0400415
|
1-[7-[4-[4-(4-chlorophenyl)piperidin-1-yl]butanoyl]-1,2,4,5-tetrahydro-3-benzazepin-3-yl]pentan-1-one
Show/Hide
|
C30H39ClN2O2
|
1
|
1 |
IC50 = 11 nM
|
|
|
CP0505227
|
2-(4-chlorophenyl)-5-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)furo[3,2-c]pyridin-4-one
Show/Hide
|
C24H18ClN3O2
|
1
|
1 |
IC50 = 11 nM
|
|
|
CP0380259
|
4-[(5-chlorothiophen-2-yl)methoxy]-1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C21H18ClN3O2S
|
1
|
1 |
IC50 = 11 nM
|
|
|
CP0396718
|
N-[6-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl]-4-(4-methylphenyl)benzamide
Show/Hide
|
C27H30N2O
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0457411
|
4-(4-chlorophenyl)-N-[6-(morpholin-4-ylmethyl)-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C28H27ClN2O2
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0472692
|
4-phenyl-N-[6-(pyrrolidin-1-ylmethyl)-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C28H28N2O
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0494590
|
4-(4-chlorophenyl)-N-[6-[[methyl(2-phenylethyl)amino]methyl]-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C33H31ClN2O
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0417411
|
5-(4-fluorophenyl)-N-[8-methyl-3-(pyrrolidin-1-ylmethyl)quinolin-7-yl]-5-oxopentanamide
Show/Hide
|
C26H28FN3O2
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0421008
|
5-(4-fluorophenyl)-N-[8-methyl-3-(pyrrolidin-1-ylmethyl)quinolin-7-yl]pentanamide
Show/Hide
|
C26H30FN3O
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0481426
|
N-[3-[(1S)-1-(2-acetamidoethylamino)ethyl]-8-methylquinolin-7-yl]-4-(cyclopropylmethoxy)benzamide
Show/Hide
|
C27H32N4O3
|
1
|
1 |
IC50 = 12 nM
|
|
|
CP0494230
|
N-[6-[[acetyl(methyl)amino]methyl]-7,8-dihydronaphthalen-2-yl]-4-(4-chlorophenyl)benzamide
Show/Hide
|
C27H25ClN2O2
|
1
|
1 |
IC50 = 13 nM
|
|
|
CP0499067
|
4-(cyclopropylmethoxy)-N-[3-[1-(2-hydroxyethylamino)ethyl]-8-methylquinolin-7-yl]benzamide
Show/Hide
|
C25H29N3O3
|
1
|
1 |
IC50 = 13 nM
|
|
|
CP0376292
|
1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)-4-[[5-(trifluoromethyl)thiophen-2-yl]methoxy]pyridin-2-one
Show/Hide
|
C22H18F3N3O2S
|
1
|
1 |
IC50 = 13 nM
|
|
|
CP0425459
|
4-(4-chlorophenyl)-N-[6-(diethylaminomethyl)-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C28H29ClN2O
|
1
|
1 |
IC50 = 14 nM
|
|
|
CP0511825
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-[[5-(trifluoromethyl)thiophen-3-yl]methoxy]pyridin-2-one
Show/Hide
|
C22H18F3N3O2S
|
1
|
1 |
IC50 = 15 nM
|
|
|
CP0387992
|
methyl 7-[4-[4-(4-chlorophenyl)piperidin-1-yl]butanoyl]-1,2,4,5-tetrahydro-3-benzazepine-3-carboxylate
Show/Hide
|
C27H33ClN2O3
|
1
|
1 |
IC50 = 17 nM
|
|
|
CP0469560
|
1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)-4-[[4-(trifluoromethyl)thiophen-2-yl]methoxy]pyridin-2-one
Show/Hide
|
C22H18F3N3O2S
|
1
|
1 |
IC50 = 17 nM
|
|
|
CP0409752
|
4-[(4-chlorothiophen-2-yl)methoxy]-1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C21H18ClN3O2S
|
1
|
1 |
IC50 = 18 nM
|
|
|
CP0410727
|
4-(cyclopropylmethoxy)-N-[3-[1-[(3S)-3-hydroxypyrrolidin-1-yl]ethyl]-8-methylquinolin-7-yl]benzamide
Show/Hide
|
C27H31N3O3
|
1
|
1 |
IC50 = 19 nM
|
|
|
CP0443346
|
4-[(5-chloropyridin-2-yl)methoxy]-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyridin-2-one
Show/Hide
|
C22H19ClN4O2
|
1
|
1 |
IC50 = 19 nM
|
|
|
CP0457412
|
4-(4-chlorophenyl)-N-[6-[(N-methylanilino)methyl]-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C31H27ClN2O
|
1
|
1 |
IC50 = 20 nM
|
|
|
CP0526880
|
4-(cyclopropylmethoxy)-N-[8-methyl-3-[1-(4-methylpiperazin-1-yl)ethyl]quinolin-7-yl]benzamide
Show/Hide
|
C28H34N4O2
|
1
|
1 |
IC50 = 20 nM
|
|
|
CP0407713
|
4-[(4-chlorophenyl)methoxy]-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyridin-2-one
Show/Hide
|
C23H20ClN3O2
|
1
|
1 |
IC50 = 20 nM
|
|
|
CP0396715
|
N-[6-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl]-4-(4-ethylphenyl)benzamide
Show/Hide
|
C28H32N2O
|
1
|
1 |
IC50 = 21 nM
|
|
|
CP0385724
|
4-[(4-chlorophenyl)methoxy]-1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C23H20ClN3O2
|
1
|
1 |
IC50 = 21 nM
|
|
|
CP0457410
|
N-[6-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl]-4-(4-methoxyphenyl)benzamide
Show/Hide
|
C27H30N2O2
|
1
|
1 |
IC50 = 22 nM
|
|
|
CP0472705
|
4-(2-chlorophenyl)-N-[6-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl]benzamide
Show/Hide
|
C26H27ClN2O
|
1
|
1 |
IC50 = 23 nM
|
|
|
CP0376428
|
4-[(4-chlorophenyl)methoxy]-1-(2-cyclopropyl-3-methylindazol-5-yl)pyridin-2-one
Show/Hide
|
C23H20ClN3O2
|
1
|
1 |
IC50 = 23 nM
|
|
|
CP0413189
|
4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide
Show/Hide
|
C26H27FN2O
|
1
|
1 |
IC50 = 24 nM
|
|
|
CP0045532
|
1-(2-cyclopropyl-3-methylindazol-5-yl)-4-[[5-(trifluoromethyl)thiophen-3-yl]methoxy]pyridin-2-one
Show/Hide
|
C22H18F3N3O2S
|
1
|
1 |
IC50 = 26 nM
|
|
|
CP0514947
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-phenylmethoxypyridin-2-one
Show/Hide
|
C23H21N3O2
|
1
|
1 |
IC50 = 28 nM
|
|
|
CP0541020
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C23H20FN3O2
|
1
|
1 |
IC50 = 28 nM
|
|
|
CP0493956
|
1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C23H20FN3O2
|
1
|
1 |
IC50 = 28 nM
|
|
|
CP0401611
|
1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)-4-(thiophen-3-ylmethoxy)pyridin-2-one
Show/Hide
|
C21H19N3O2S
|
1
|
1 |
IC50 = 29 nM
|
|
|
CP0535732
|
1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)-4-[[5-(trifluoromethyl)thiophen-3-yl]methoxy]pyridin-2-one
Show/Hide
|
C22H18F3N3O2S
|
1
|
1 |
IC50 = 29 nM
|
|
|
CP0541023
|
4-[(4-chlorophenyl)methoxy]-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyrimidin-2-one
Show/Hide
|
C22H19ClN4O2
|
1
|
1 |
IC50 = 30 nM
|
|
|
CP0566686
|
4-[(4-chlorophenyl)methoxy]-1-(2-cyclopropyl-3-ethylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C24H22ClN3O2
|
1
|
1 |
IC50 = 34 nM
|
|
|
CP0386236
|
1-(2-cyclopropyl-3-methylindazol-5-yl)-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C23H20FN3O2
|
1
|
1 |
IC50 = 35 nM
|
|
|
CP0431626
|
4-[(4-chlorophenyl)methoxy]-1-(2,3-dimethylindazol-5-yl)pyridin-2-one
Show/Hide
|
C21H18ClN3O2
|
1
|
1 |
IC50 = 36 nM
|
|
|
CP0483332
|
1-(2,3-dimethylindazol-5-yl)-4-[[4-(trifluoromethyl)thiophen-2-yl]methoxy]pyridin-2-one
Show/Hide
|
C20H16F3N3O2S
|
1
|
1 |
IC50 = 38 nM
|
|
|
CP0386059
|
1-(2-ethyl-3-methylbenzimidazol-5-yl)-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C22H20FN3O2
|
1
|
1 |
IC50 = 38 nM
|
|
|
CP0534663
|
4-[(4-fluorophenyl)methoxy]-1-(3-methyl-2-propylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C23H22FN3O2
|
1
|
1 |
IC50 = 39 nM
|
|
|
CP0499816
|
1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)-4-phenylmethoxypyridin-2-one
Show/Hide
|
C23H21N3O2
|
1
|
1 |
IC50 = 43 nM
|
|
|
CP0409754
|
4-[(5-chloropyridin-2-yl)methoxy]-1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C22H19ClN4O2
|
1
|
1 |
IC50 = 47 nM
|
|
|
CP0414890
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-(thiophen-3-ylmethoxy)pyridin-2-one
Show/Hide
|
C21H19N3O2S
|
1
|
1 |
IC50 = 54 nM
|
|
|
CP0514948
|
2-(4-chlorophenyl)-6-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-3,4-dihydro-2H-pyrano[3,2-c]pyridin-5-one
Show/Hide
|
C25H22ClN3O2
|
1
|
1 |
IC50 = 62 nM
|
|
|
CP0499146
|
ethyl N-[[6-[[4-(4-chlorophenyl)benzoyl]amino]-3,4-dihydronaphthalen-2-yl]methyl]-N-methylcarbamate
Show/Hide
|
C28H27ClN2O3
|
1
|
1 |
IC50 = 64 nM
|
|
|
CP0399280
|
4-[(4-chlorophenyl)methoxy]-1-(2-ethyl-3-methylindazol-5-yl)pyridin-2-one
Show/Hide
|
C22H20ClN3O2
|
1
|
1 |
IC50 = 65 nM
|
|
|
CP0386058
|
1-(2,3-dimethylbenzimidazol-5-yl)-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C21H18FN3O2
|
1
|
1 |
IC50 = 65 nM
|
|
|
CP0457413
|
4-(4-chlorophenyl)-N-[6-[[ethylcarbamoyl(methyl)amino]methyl]-7,8-dihydronaphthalen-2-yl]benzamide
Show/Hide
|
C28H28ClN3O2
|
1
|
1 |
IC50 = 70 nM
|
|
|
CP0483333
|
1-(2,3-dimethylindazol-5-yl)-4-[[5-(trifluoromethyl)thiophen-3-yl]methoxy]pyridin-2-one
Show/Hide
|
C20H16F3N3O2S
|
1
|
1 |
IC50 = 70 nM
|
|
|
CP0380257
|
4-[(3-chlorophenyl)methoxy]-1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C23H20ClN3O2
|
1
|
1 |
IC50 = 72 nM
|
|
|
CP0469562
|
1-(2,3-dimethylindazol-5-yl)-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C21H18FN3O2
|
1
|
1 |
IC50 = 76 nM
|
|
|
CP0508802
|
1-(2,3-dimethylindazol-5-yl)-4-[[4-(trifluoromethyl)-1,3-thiazol-2-yl]methoxy]pyridin-2-one
Show/Hide
|
C19H15F3N4O2S
|
1
|
1 |
IC50 = 76 nM
|
|
|
CP0418771
|
1-(3-benzoyl-1,2,4,5-tetrahydro-3-benzazepin-7-yl)-4-[4-(4-chlorophenyl)piperidin-1-yl]butan-1-one
Show/Hide
|
C32H35ClN2O2
|
1
|
1 |
IC50 = 79 nM
|
|
|
CP0393454
|
4-[4-(4-chlorophenyl)piperidin-1-yl]-1-(6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl)butan-1-one
Show/Hide
|
C26H32ClNO
|
1
|
1 |
IC50 = 80 nM
|
|
|
CP0414880
|
1-(2,3-dimethylimidazo[1,2-a]pyridin-6-yl)-4-phenylmethoxypyridin-2-one
Show/Hide
|
C21H19N3O2
|
1
|
1 |
IC50 = 80 nM
|
|
|
CP0468317
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-[[4-(trifluoromethyl)phenyl]methoxy]pyridin-2-one
Show/Hide
|
C24H20F3N3O2
|
1
|
1 |
IC50 = 82 nM
|
|
|
CP0394860
|
1-(2-acetyl-1,3,4,5-tetrahydro-2-benzazepin-8-yl)-4-[4-(4-chlorophenyl)piperidin-1-yl]butan-1-one
Show/Hide
|
C27H33ClN2O2
|
1
|
1 |
IC50 = 86 nM
|
|
|
CP0475744
|
N-[8-methyl-3-(pyrrolidin-1-ylmethyl)quinolin-7-yl]-4-(pentanoylamino)benzamide
Show/Hide
|
C27H32N4O2
|
1
|
1 |
IC50 = 90 nM
|
|
|
CP0469563
|
1-(2,3-dimethylindazol-5-yl)-4-[[5-(trifluoromethyl)thiophen-2-yl]methoxy]pyridin-2-one
Show/Hide
|
C20H16F3N3O2S
|
1
|
1 |
IC50 = 90 nM
|
|
|
CP0472704
|
N-[6-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl]-4-phenylbenzamide
Show/Hide
|
C26H28N2O
|
1
|
1 |
IC50 = 95 nM
|
|
|
CP0468318
|
5-[(4-chlorophenyl)methoxy]-2-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyridazin-3-one
Show/Hide
|
C22H19ClN4O2
|
1
|
1 |
IC50 = 110 nM
|
|
|
CP0549408
|
4-[(4-chlorophenyl)methoxy]-1-(2-cyclopropyl-3-propylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C25H24ClN3O2
|
1
|
1 |
IC50 = 110 nM
|
|
|
CP0407715
|
1-(2-ethyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-phenylmethoxypyridin-2-one
Show/Hide
|
C22H21N3O2
|
1
|
1 |
IC50 = 120 nM
|
|
|
CP0380258
|
1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)-4-(thiophen-2-ylmethoxy)pyridin-2-one
Show/Hide
|
C21H19N3O2S
|
1
|
1 |
IC50 = 120 nM
|
|
|
CP0468327
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-(thiophen-2-ylmethoxy)pyridin-2-one
Show/Hide
|
C21H19N3O2S
|
1
|
1 |
IC50 = 130 nM
|
|
|
CP0399279
|
4-[(4-chlorophenyl)methoxy]-1-(3-methyl-2-propylindazol-5-yl)pyridin-2-one
Show/Hide
|
C23H22ClN3O2
|
1
|
1 |
IC50 = 130 nM
|
|
|
CP0535734
|
1-(2,3-dimethylindazol-5-yl)-4-[[2-(trifluoromethyl)-1,3-thiazol-4-yl]methoxy]pyridin-2-one
Show/Hide
|
C19H15F3N4O2S
|
1
|
1 |
IC50 = 130 nM
|
|
|
CP0452309
|
6-[(4-chlorophenyl)methoxy]-3-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyrimidin-4-one
Show/Hide
|
C22H19ClN4O2
|
1
|
1 |
IC50 = 140 nM
|
|
|
CP0420422
|
4-[(2-chlorophenyl)methoxy]-1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C23H20ClN3O2
|
1
|
1 |
IC50 = 140 nM
|
|
|
CP0490511
|
1-[2-(cyclopropylmethyl)-3-methylbenzimidazol-5-yl]-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C24H22FN3O2
|
1
|
1 |
IC50 = 140 nM
|
|
|
CP0443354
|
4-[(4-chlorophenyl)methoxy]-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-5-methylpyridin-2-one
Show/Hide
|
C24H22ClN3O2
|
1
|
1 |
IC50 = 150 nM
|
|
|
CP0541022
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-(pyridin-2-ylmethoxy)pyridin-2-one
Show/Hide
|
C22H20N4O2
|
1
|
1 |
IC50 = 150 nM
|
|
|
CP0468316
|
2-[6-[4-[(4-fluorophenyl)methoxy]-2-oxopyridin-1-yl]-3-methylimidazo[1,2-a]pyridin-2-yl]acetonitrile
Show/Hide
|
C22H17FN4O2
|
1
|
1 |
IC50 = 170 nM
|
|
|
CP0466561
|
N-[6-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl]-4-(4-propylphenyl)benzamide
Show/Hide
|
C29H34N2O
|
1
|
1 |
IC50 = 210 nM
|
|
|
CP0386061
|
1-(2-cyclobutyl-3-methylbenzimidazol-5-yl)-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C24H22FN3O2
|
1
|
1 |
IC50 = 210 nM
|
|
|
CP0501684
|
4-(3-chlorophenyl)-N-[6-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl]benzamide
Show/Hide
|
C26H27ClN2O
|
1
|
1 |
IC50 = 220 nM
|
|
|
CP0407718
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-3-[4-(trifluoromethoxy)phenoxy]pyridin-2-one
Show/Hide
|
C23H18F3N3O3
|
1
|
1 |
IC50 = 240 nM
|
|
|
CP0565750
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-[(4-propan-2-ylphenyl)methoxy]pyridin-2-one
Show/Hide
|
C26H27N3O2
|
1
|
1 |
IC50 = 240 nM
|
|
|
CP0425456
|
tert-butyl N-[[6-[[4-(4-chlorophenyl)benzoyl]amino]-3,4-dihydronaphthalen-2-yl]methyl]-N-methylcarbamate
Show/Hide
|
C30H31ClN2O3
|
1
|
1 |
IC50 = 250 nM
|
|
|
CP0466399
|
[6-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl] 4-phenylbenzoate
Show/Hide
|
C26H27NO2
|
1
|
1 |
IC50 = 280 nM
|
|
|
CP0511116
|
1-(2-cyclopentyl-3-methylbenzimidazol-5-yl)-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C25H24FN3O2
|
1
|
1 |
IC50 = 460 nM
|
|
|
CP0443353
|
3-[(4-chlorophenyl)methoxy]-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyridin-2-one
Show/Hide
|
C23H20ClN3O2
|
1
|
1 |
IC50 = 650 nM
|
|
|
CP0566685
|
4-[(5-chloropyrimidin-2-yl)methoxy]-1-(2-cyclopropyl-3-methylbenzimidazol-5-yl)pyridin-2-one
Show/Hide
|
C21H18ClN5O2
|
1
|
1 |
IC50 = 900 nM
|
|
|
CP0407717
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-[4-(trifluoromethoxy)phenoxy]pyridin-2-one
Show/Hide
|
C23H18F3N3O3
|
1
|
1 |
IC50 = 950 nM
|
|
|
CP0498830
|
N-[6-[(dimethylamino)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl]-4-phenylbenzenesulfonamide
Show/Hide
|
C25H28N2O2S
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0526609
|
6-[(dimethylamino)methyl]-N-[(4-phenylphenyl)methyl]-5,6,7,8-tetrahydronaphthalen-2-amine
Show/Hide
|
C26H30N2
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0443347
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-(pyrimidin-5-ylmethoxy)pyridin-2-one
Show/Hide
|
C21H19N5O2
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0443348
|
4-[(4-fluorophenyl)methoxy]-1-[2-(methoxymethyl)-3-methylimidazo[1,2-a]pyridin-6-yl]pyridin-2-one
Show/Hide
|
C22H20FN3O3
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0443349
|
4-[(4-fluorophenyl)methoxy]-1-[2-(hydroxymethyl)-3-methylimidazo[1,2-a]pyridin-6-yl]pyridin-2-one
Show/Hide
|
C21H18FN3O3
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0443355
|
6-[4-[(4-fluorophenyl)methoxy]-2-oxopyridin-1-yl]-N,N,3-trimethylimidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C23H21FN4O3
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0443357
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-(pyridin-3-ylmethoxy)pyridin-2-one
Show/Hide
|
C22H20N4O2
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0452304
|
6-[4-[(4-fluorophenyl)methoxy]-2-oxopyridin-1-yl]-3-methylimidazo[1,2-a]pyridine-2-carbonitrile
Show/Hide
|
C21H15FN4O2
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0452345
|
1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-(pyridin-4-ylmethoxy)pyridin-2-one
Show/Hide
|
C22H20N4O2
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0468319
|
1-(2-acetyl-3-methylimidazo[1,2-a]pyridin-6-yl)-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C22H18FN3O3
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0505228
|
1-[2-(cyclopropanecarbonyl)-3-methylimidazo[1,2-a]pyridin-6-yl]-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C24H20FN3O3
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0541019
|
N-(2-cyclopropyl-3-methylindolizin-6-yl)-2-[4-(trifluoromethoxy)phenoxy]acetamide
Show/Hide
|
C21H19F3N2O3
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0541024
|
N-(2,3-dimethyl-1-benzofuran-5-yl)-2-[4-(trifluoromethoxy)phenoxy]acetamide
Show/Hide
|
C19H16F3NO4
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0380256
|
1-[2-(2,2-dimethylpropyl)-3-methylbenzimidazol-5-yl]-4-[(4-fluorophenyl)methoxy]pyridin-2-one
Show/Hide
|
C25H26FN3O2
|
1
|
1 |
IC50 > 1000 nM
|
|
|