General Information of the Compound
| Compound ID |
CP0407728
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| Compound Name |
4-[(5-chlorothiophen-3-yl)methoxy]-1-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)pyridin-2-one
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| Structure |
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| Formula |
C21H18ClN3O2S
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| Molecular Weight |
411.914
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| Canonical SMILES |
Cc1c(nc2ccc(cn12)-n1ccc(OCc2csc(Cl)c2)cc1=O)C1CC1
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| InChI |
InChI=1S/C21H18ClN3O2S/c1-13-21(15-2-3-15)23-19-5-4-16(10-25(13)19)24-7-6-17(9-20(24)26)27-11-14-8-18(22)28-12-14/h4-10,12,15H,2-3,11H2,1H3
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| InChIKey |
QNVFWMGJWHJVJJ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01388, Melanin-concentrating hormone receptor 1
Protein ID: PT01027, Melanin-concentrating hormone receptor 1