| Compound ID |
Compound Name |
Compound Formula |
|
CP0579435
|
2-[6-(difluoromethyl)pyridin-2-yl]-1-(2-methoxy-5-methylphenyl)-N-(2-methylquinolin-5-yl)sulfonylcyclopropane-1-carboxamide
Show/Hide
|
C28H25F2N3O4S
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0571389
|
1-(2-methoxy-5-methylphenyl)-N-(2-methylquinolin-5-yl)sulfonyl-2-[3-(trifluoromethyl)phenyl]cyclopropane-1-carboxamide
Show/Hide
|
C29H25F3N2O4S
|
1
|
| 1 |
EC50 = 0.51 nM
|
|
|
|
CP0575716
|
1-(2-methoxy-5-methylphenyl)-2-(4-methoxyphenyl)-N-(2-methylquinolin-5-yl)sulfonylcyclopropane-1-carboxamide
Show/Hide
|
C29H28N2O5S
|
1
|
| 1 |
EC50 = 0.66 nM
|
|
|
|
CP0571732
|
1-(2-methoxy-5-methylphenyl)-2-(4-methylphenyl)-N-(2-methylquinolin-5-yl)sulfonylcyclopropane-1-carboxamide
Show/Hide
|
C29H28N2O4S
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0571138
|
1-(2-methoxy-5-methylphenyl)-2-(3-methoxyphenyl)-N-(2-methylquinolin-5-yl)sulfonylcyclopropane-1-carboxamide
Show/Hide
|
C29H28N2O5S
|
1
|
| 1 |
EC50 = 0.84 nM
|
|
|
|
CP0578716
|
1-(2-methoxy-5-methylphenyl)-N-(2-methylquinolin-5-yl)sulfonyl-2-(6-propan-2-yloxypyridin-2-yl)cyclopropane-1-carboxamide
Show/Hide
|
C30H31N3O5S
|
1
|
| 1 |
EC50 = 0.9 nM
|
|
|
|
CP0388845
|
N-(4-tert-butyl-3-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
Show/Hide
|
C20H20N2O3
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0362762
|
3-amino-N-[(2S)-2-hydroxypropyl]-5-[4-(trifluoromethoxy)phenyl]sulfonylpyridine-2-carboxamide
Show/Hide
|
C16H16F3N3O5S
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0088272
|
CHEBI:66901
Show/Hide
|
C24H28N2O3
|
4
|
| 1 |
EC50 = 22 nM
|
|
|
| 2 |
EC50 = 34 nM
|
|
|
| 3 |
EC50 = 68 nM
|
|
|
| 4 |
EC50 = 236 nM
|
|
|
|
CP0490597
|
N-[4-tert-butyl-5-hydroxy-2-(trifluoromethyl)phenyl]-4-oxo-1H-quinoline-3-carboxamide
Show/Hide
|
C21H19F3N2O3
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0494908
|
(2S,3S,4S,5S)-3-tert-butyl-4-(2-methylanilino)-1-[(2S)-oxane-2-carbonyl]-5-(2-propan-2-ylphenyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C31H42N2O4
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0532736
|
3-Amino-6-bromo-5-trifluoromethyl-pyridine-2-carboxylic acid ((S)-3,3,3-trifluoro-2-hydroxy-2-methyl-propyl)-amide
Show/Hide
|
C11H10BrF6N3O2
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0551217
|
US10117858, Example 5
Show/Hide
|
C12H13F6N3O3
|
2
|
| 1 |
EC50 = 39 nM
|
|
|
| 2 |
EC50 = 72 nM
|
|
|
|
CP0527765
|
(2S,3S,4S,5S)-3-tert-butyl-5-[(5-cyclobutyl-2-methoxypyridin-3-yl)methyl]-4-[(5-cyclobutyl-2-methoxypyridin-3-yl)methylamino]-1-[(2S)-oxane-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C37H52N4O6
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0387052
|
N-(3-tert-butyl-1H-indol-6-yl)-4-oxo-1H-quinoline-3-carboxamide
Show/Hide
|
C22H21N3O2
|
1
|
| 1 |
EC50 = 42 nM
|
|
|
|
CP0400231
|
N-(4-tert-butyl-2-fluoro-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
Show/Hide
|
C20H19FN2O3
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0494401
|
N-(5-tert-butyl-1H-indol-6-yl)-4-oxo-1H-quinoline-3-carboxamide
Show/Hide
|
C22H21N3O2
|
1
|
| 1 |
EC50 = 97 nM
|
|
|
|
CP0532463
|
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-tert-butyl-2-methoxypyridin-3-yl)methylamino]-1-(cyclohexanecarbonyl)-5-phenylpyrrolidine-2-carboxylic acid
Show/Hide
|
C33H47N3O4
|
1
|
| 1 |
EC50 = 107 nM
|
|
|
|
CP0562768
|
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-tert-butyl-2-methoxyphenyl)methylamino]-1-(cyclohexanecarbonyl)-5-phenylpyrrolidine-2-carboxylic acid
Show/Hide
|
C34H48N2O4
|
1
|
| 1 |
EC50 = 113 nM
|
|
|
|
CP0527833
|
(2S,3S,4S,5S)-4-[[5-(1-adamantyl)-2-methoxyphenyl]methylamino]-3-tert-butyl-1-(cyclohexanecarbonyl)-5-phenylpyrrolidine-2-carboxylic acid
Show/Hide
|
C40H54N2O4
|
1
|
| 1 |
EC50 = 136 nM
|
|
|
|
CP0353054
|
(2S,3S,4S,5S)-3-tert-butyl-4-[[2-(dimethylamino)pyridin-3-yl]amino]-1-[(2S)-oxane-2-carbonyl]-5-(2-propan-2-ylphenyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C31H44N4O4
|
1
|
| 1 |
EC50 = 142 nM
|
|
|
|
CP0569896
|
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-tert-butyl-2-methoxyphenyl)methylamino]-5-[[2-methoxy-5-(trifluoromethyl)pyridin-3-yl]methyl]-1-[(2S)-oxane-2-carbonyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C35H48F3N3O6
|
1
|
| 1 |
EC50 = 159 nM
|
|
|
|
CP0576906
|
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-cyclobutyl-2-methoxypyridin-3-yl)methylamino]-1-(cyclohexanecarbonyl)-5-phenylpyrrolidine-2-carboxylic acid
Show/Hide
|
C33H45N3O4
|
1
|
| 1 |
EC50 = 184 nM
|
|
|
|
CP0532464
|
(2S,3S,4S,5S)-3-tert-butyl-1-(cyclohexanecarbonyl)-4-[(2-methoxy-5-propan-2-ylphenyl)methylamino]-5-phenylpyrrolidine-2-carboxylic acid
Show/Hide
|
C33H46N2O4
|
1
|
| 1 |
EC50 = 188 nM
|
|
|
|
CP0575054
|
(2S,3S,4S,5S)-3-tert-butyl-1-(cyclohexanecarbonyl)-4-[[2-methoxy-5-(3-tricyclo[3.1.0.01,3]hexanyl)phenyl]methylamino]-5-phenylpyrrolidine-2-carboxylic acid
Show/Hide
|
C36H46N2O4
|
1
|
| 1 |
EC50 = 190 nM
|
|
|
|
CP0527764
|
(2S,3S,4S,5S)-3-tert-butyl-1-(cyclohexanecarbonyl)-4-[[2-methoxy-5-(trifluoromethyl)pyridin-3-yl]methylamino]-5-phenylpyrrolidine-2-carboxylic acid
Show/Hide
|
C30H38F3N3O4
|
1
|
| 1 |
EC50 = 210 nM
|
|
|
|
CP0543195
|
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-chloro-2-methoxyphenyl)methylamino]-1-(cyclohexanecarbonyl)-5-phenylpyrrolidine-2-carboxylic acid
Show/Hide
|
C30H39ClN2O4
|
1
|
| 1 |
EC50 = 241 nM
|
|
|
|
CP0575055
|
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-tert-butyl-2-methoxyphenyl)methylamino]-1-[(2S)-oxane-2-carbonyl]-5-phenylpyrrolidine-2-carboxylic acid
Show/Hide
|
C33H46N2O5
|
1
|
| 1 |
EC50 = 321 nM
|
|
|
|
CP0550164
|
(6R,12R)-17-amino-12-(hydroxymethyl)-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
Show/Hide
|
C17H18F6N4O4
|
1
|
| 1 |
EC50 < 500 nM
|
|
|
|
CP0550165
|
(6R,12R)-17-amino-8,9-dideuterio-12-methyl-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
Show/Hide
|
C17H18F6N4O3
|
1
|
| 1 |
EC50 < 500 nM
|
|
|
|
CP0550166
|
(6R)-17-amino-11,11-dimethyl-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
Show/Hide
|
C18H20F6N4O3
|
1
|
| 1 |
EC50 < 500 nM
|
|
|
|
CP0577539
|
(6R,12S)-17-amino-12-methyl-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
Show/Hide
|
C17H18F6N4O3
|
1
|
| 1 |
EC50 < 500 nM
|
|
|
|
CP0579031
|
17-amino-6,15-bis(trifluoromethyl)-13,19-dioxa-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
Show/Hide
|
C16H16F6N4O3
|
1
|
| 1 |
EC50 < 500 nM
|
|
|
|
CP0579780
|
(6R)-17-amino-6,15-bis(trifluoromethyl)-19-oxa-13-thia-3,4,18-triazatricyclo[12.3.1.12,5]nonadeca-1(17),2,4,14(18),15-pentaen-6-ol
Show/Hide
|
C16H16F6N4O2S
|
1
|
| 1 |
EC50 < 500 nM
|
|
|
|
CP0385469
|
7,9-Dimethyl-6-(5-methyl-furan-2-yl)-11-phenyl-6,7-dihydro-5H-5,7,9,11a-tetraaza-benzo[a]fluorene-8,10-dione
Show/Hide
|
C26H22N4O3
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
