[3-[[2-[3-(difluoromethyl)-2-fluoro-5-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]anilino]-5-methylpyrimidin-4-yl]amino]phenyl]methanol

4-N-[(2R)-butan-2-yl]-2-N-[2-fluoro-5-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyridin-3-yl]-5-methylpyrimidine-2,4-diamine

[3-[[2-[3-(difluoromethyl)-5-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]anilino]-5-methylpyrimidin-4-yl]amino]phenyl]methanol

2-N-[2-fluoro-5-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyridin-3-yl]-5-methyl-4-N-pentan-3-ylpyrimidine-2,4-diamine

2-N-[2-fluoro-5-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyridin-3-yl]-5-methyl-4-N-[(2R)-3-methylbutan-2-yl]pyrimidine-2,4-diamine

[3-[[2-[[2-fluoro-5-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyridin-3-yl]amino]-5-methylpyrimidin-4-yl]amino]phenyl]methanol

[3-[[5-methyl-2-[3-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]-5-methylsulfonylanilino]pyrimidin-4-yl]amino]phenyl]methanol

[3-[[5-methyl-2-[3-(4-methylpiperazin-1-yl)-5-methylsulfonylanilino]pyrimidin-4-yl]amino]phenyl]methanol

[3-[[2-[2-fluoro-5-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]anilino]-5-methylpyrimidin-4-yl]amino]phenyl]methanol

[3-[[2-[3-[4-(2-methoxyethyl)piperazin-1-yl]-5-methylsulfonylanilino]-5-methylpyrimidin-4-yl]amino]phenyl]methanol

[3-[[2-[3-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-5-methylsulfonylanilino]-5-methylpyrimidin-4-yl]amino]phenyl]methanol

[3-[[5-methyl-2-(3-methylsulfonyl-5-piperazin-1-ylanilino)pyrimidin-4-yl]amino]phenyl]methanol

2-[4-[3-[[4-[3-(hydroxymethyl)anilino]-5-methylpyrimidin-2-yl]amino]-5-methylsulfonylphenyl]piperazin-1-yl]ethanol

1-[4-[3-[[4-[3-(hydroxymethyl)anilino]-5-methylpyrimidin-2-yl]amino]-5-methylsulfonylphenyl]piperazin-1-yl]ethanone

6-chloro-2-(4-methoxyphenyl)-N-(piperidin-4-ylmethyl)-1H-imidazo[4,5-b]pyridin-7-amine

6-chloro-2-(2-fluoro-4-methoxyphenyl)-N-(piperidin-4-ylmethyl)-1H-imidazo[4,5-b]pyridin-7-amine

6-chloro-2-(4-methoxy-2-methylphenyl)-N-(piperidin-4-ylmethyl)-1H-imidazo[4,5-b]pyridin-7-amine

6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-N-(piperidin-4-ylmethyl)-1H-imidazo[4,5-b]pyridin-7-amine

(2R)-N-(3-{2- [(1,3-dimethyl-1H- pyrazol-4-yl)amino]-5- fluoropyimidin-4-yl}- 1H-indol-7-yl)-3-methoxy- 2-(4-methylpiperazin-1- yl)propanamide

(2R)-N-(3-(5-chloro-2-(3-methoxy-1-methyl-1H-pyrazol-4-ylamino)pyrimidin-4-yl)-1H-indol-7-yl)-2-(4-methylpiperazin-1-yl)propanamide

6-chloro-2-(2,5-difluoro-4-methoxyphenyl)-N-(piperidin-4-ylmethyl)-1H-imidazo[4,5-b]pyridin-7-amine

(2R)-N-(3-(2-(1,3-dimethyl-1H-pyrazol-4-ylamino)-5-fluoropyrimidin-4-yl)-1H-indol-7-yl)-2-(4-methylpiperazin-1-yl)butanamide

6-chloro-2-(2-fluoro-5-methoxyphenyl)-N-(piperidin-4-ylmethyl)-1H-imidazo[4,5-b]pyridin-7-amine

(2R)-N-[3-[2-[(2-fluoropyridin-3-yl)amino]-5-methylpyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propanamide

6-chloro-2-(3,4-dimethoxyphenyl)-N-(piperidin-4-ylmethyl)-1H-imidazo[4,5-b]pyridin-7-amine

(2R)-N-[3-[5-bromo-2-[(3-methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propanamide

(2R)-N-(3-(2-(3-ethoxy-1-methyl-1H-pyrazol-4-ylamino)-5-methylpyrimidin-4-yl)-1H-indol-7-yl)-2-(4-methylpiperazin-1-yl)butanamide

(2R)-N-[3-[5-fluoro-2-[(3-methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propanamide

(2R)-N-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propanamide

(2R)-N-[3-[2-[(3-methoxy-1-methyl-pyrazol-4-yl)amino]-5-methyl-pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propanamide

(2R)-N-[3-[5-methyl-2-[(2-methylpyridin-3-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propanamide

(R)-2-((S)-2,4-dimethylpiperazin-1-yl)-N-(3-(2-(3-methoxy-1-methyl-1H-pyrazol-4-ylamino)pyrimidin-4-yl)-1H-indol-7-yl)propanamide

(2S)-2-((S)-2,4-dimethylpiperazin-1-yl)-N-(3-(2-(3-ethoxy-1-methyl-1H-pyrazol-4-ylamino)-5-fluoropyrimidin-4-yl)-1H-indol-7-yl)propanamide