Brief Information of the Compound and Protein
Compound Name
6-chloro-2-(2,5-difluoro-4-methoxyphenyl)-N-(piperidin-4-ylmethyl)-1H-imidazo[4,5-b]pyridin-7-amine
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PubChem ID
CID: 127038947
Canonical SMILES
COc1cc(F)c(cc1F)-c1nc2c(NCC3CCNCC3)c(Cl)cnc2[nH]1
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Compound Formula C19H20ClF2N5O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000157 NCI-H1975 Homo sapiens (Human)  1
1
IC50 = 71 nM
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