Brief Information of the Compound and Protein
Compound Name
[3-[[2-[3-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-5-methylsulfonylanilino]-5-methylpyrimidin-4-yl]amino]phenyl]methanol
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PubChem ID
CID: 145952312
Canonical SMILES
C[C@H]1CN(C[C@@H](C)N1)c1cc(Nc2ncc(C)c(Nc3cccc(CO)c3)n2)cc(c1)S(C)(=O)=O
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Compound Formula C25H32N6O3S
Compound Structure
Protein Name
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000157 NCI-H1975 Homo sapiens (Human)  1
1
EC50 = 325 nM
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