Brief Information of the Compound and Protein
Compound Name
[3-[[2-[3-(difluoromethyl)-2-fluoro-5-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl]anilino]-5-methylpyrimidin-4-yl]amino]phenyl]methanol
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PubChem ID
CID: 145971190
Canonical SMILES
CN1C[C@@H]2C[C@H]1CN2c1cc(Nc2ncc(C)c(Nc3cccc(CO)c3)n2)c(F)c(c1)C(F)F
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Compound Formula C25H27F3N6O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000157 NCI-H1975 Homo sapiens (Human)  1
1
EC50 = 26 nM
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