Brief Information of the Compound and Protein
Compound Name
(2S)-2-((S)-2,4-dimethylpiperazin-1-yl)-N-(3-(2-(3-ethoxy-1-methyl-1H-pyrazol-4-ylamino)-5-fluoropyrimidin-4-yl)-1H-indol-7-yl)propanamide
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PubChem ID
CID: 126715363
Canonical SMILES
CCOc1nn(C)cc1Nc1ncc(F)c(-c2c[nH]c3c(NC(=O)[C@H](C)N4CCN(C)C[C@@H]4C)cccc23)n1
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Compound Formula C27H34FN9O2
Compound Structure
Protein Name
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000157 NCI-H1975 Homo sapiens (Human)  1
1
IC50 > 3000 nM
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