Brief Information of the Compound and Protein
Compound Name
2-[4-[3-[[4-[3-(hydroxymethyl)anilino]-5-methylpyrimidin-2-yl]amino]-5-methylsulfonylphenyl]piperazin-1-yl]ethanol
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PubChem ID
CID: 145971514
Canonical SMILES
Cc1cnc(Nc2cc(cc(c2)S(C)(=O)=O)N2CCN(CCO)CC2)nc1Nc1cccc(CO)c1
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Compound Formula C25H32N6O4S
Compound Structure
Protein Name
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000157 NCI-H1975 Homo sapiens (Human)  1
1
EC50 > 3000 nM
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