General Information of the Cell Line
Cell Line ID
CL000265
Cell Line Name
NS0
Synonyms
NSO
NS/0
NS/O
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_3940
Disease
Mouse plasma cell myeloma (NCIt: C125417)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00842, 72 kDa type IV collagenase
 Protein Info 
Compound ID Compound Name Compound Formula
CP0081310
 Compound Info 
N-(2-aminoethyl)-4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]benzenesulfonamide
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C22H24N4O3S2
  1
1
IC50 = 730 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0205581
 Compound Info 
N-[(1R,2S)-2-aminocyclohexyl]-4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]benzenesulfonamide
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C26H30N4O3S2
  1
1
IC50 = 2700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0117835
 Compound Info 
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2R)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
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C25H27FN4O4S
  1
1
IC50 = 3100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0081308
 Compound Info 
N-[(1R,2R)-2-aminocyclohexyl]-4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]benzenesulfonamide
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C26H30N4O3S2
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099232
 Compound Info 
5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]-N-[(2S)-3-methyl-1-(methylamino)-1-oxobutan-2-yl]furan-2-carboxamide
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C25H27FN4O4S
  1
1
IC50 > 5000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0159081
 Compound Info 
N-[(1R)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
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C28H31FN4O4S
  1
1
IC50 > 5000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0228996
 Compound Info 
N-(2-hydroxyethyl)-4-[4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]benzenesulfonamide
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C22H23N3O4S2
  1
1
IC50 > 5000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0228998
 Compound Info 
N-[(1S)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]-5-[3-fluoro-4-[(4-oxo-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)sulfanylmethyl]phenyl]furan-2-carboxamide
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C28H31FN4O4S
  1
1
IC50 > 5000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT02235, Cocaine esterase
 Protein Info 
Protein ID: PT01276, Collagenase 3
 Protein Info 
Protein ID: PT06778, Frizzled-1
 Protein Info 
Protein ID: PT00848, Interstitial collagenase
 Protein Info 
Protein ID: PT02569, Kallikrein-14
 Protein Info 
Protein ID: PT04137, Kallikrein-8
 Protein Info 
Protein ID: PT04868, Lysyl oxidase homolog 2
 Protein Info 
Protein ID: PT00900, Neutrophil collagenase
 Protein Info 
Protein ID: PT02196, Plasma kallikrein
 Protein Info 
Protein ID: PT00822, Prothrombin
 Protein Info 
Protein ID: PT03005, Serine protease hepsin
 Protein Info 
Protein ID: PT03015, Stratum corneum chymotryptic enzyme
 Protein Info 
Protein ID: PT01043, Urokinase-type plasminogen activator
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0219509
 Compound Info 
6-[(2-amino-3-chloropyridin-4-yl)methoxy]-N-cyclohexyl-1,3-benzothiazol-2-amine
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 C19H21ClN4OS  1
1
IC50 = 41666 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line