| Compound ID |
Compound Name |
Compound Formula |
|
CP0384458
|
[5-[3-(1-methylpyrazol-4-yl)-5-methylsulfonylphenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C15H16N4O4S3
|
3
|
| 1 |
IC50 = 69 nM
|
|
|
| 2 |
IC50 = 109 nM
|
|
|
| 3 |
IC50 = 331 nM
|
|
|
|
CP0528271
|
[5-(3-methylsulfonyl-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C17H16N2O4S3
|
3
|
| 1 |
IC50 = 69 nM
|
|
|
| 2 |
IC50 = 86 nM
|
|
|
| 3 |
IC50 = 587 nM
|
|
|
|
CP0326412
|
CHEBI:27413
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|
C3H6N2
|
4
|
| 1 |
IC50 = 73 nM
|
|
|
| 2 |
IC50 = 372 nM
|
|
|
| 3 |
IC50 = 665 nM
|
|
|
| 4 |
IC50 = 4260 nM
|
|
|
|
CP0384459
|
[5-[3-ethyl-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C16H18N4O2S2
|
3
|
| 1 |
IC50 = 78 nM
|
|
|
| 2 |
IC50 = 151 nM
|
|
|
| 3 |
IC50 = 687 nM
|
|
|
|
CP0421556
|
[4-(3-methylsulfonyl-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C17H16N2O4S3
|
3
|
| 1 |
IC50 = 85 nM
|
|
|
| 2 |
IC50 = 302 nM
|
|
|
| 3 |
IC50 = 530 nM
|
|
|
|
CP0439960
|
[5-[3-(4-methylphenyl)-5-methylsulfonylphenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C18H18N2O4S3
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0528276
|
(5-naphthalen-2-ylsulfonyl-1,3-thiazol-2-yl)methanamine
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|
C14H12N2O2S2
|
3
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 280 nM
|
|
|
| 3 |
IC50 = 690 nM
|
|
|
|
CP0363427
|
[5-(3-methylsulfonyl-5-phenylphenyl)sulfonylthiophen-2-yl]methanamine
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|
C18H17NO4S3
|
3
|
| 1 |
IC50 = 126 nM
|
|
|
| 2 |
IC50 = 176 nM
|
|
|
| 3 |
IC50 = 439 nM
|
|
|
|
CP0559457
|
[5-[3-fluoro-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C14H13FN4O2S2
|
1
|
| 1 |
IC50 = 143 nM
|
|
|
|
CP0426167
|
[4-[3-(1-methylpyrazol-4-yl)-5-methylsulfonylphenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C15H16N4O4S3
|
3
|
| 1 |
IC50 = 146 nM
|
|
|
| 2 |
IC50 = 370 nM
|
|
|
| 3 |
IC50 = 787 nM
|
|
|
|
CP0037451
|
1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane
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|
C10H20N2S4
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0068761
|
MLS000069752
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|
C6H12N2S4
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0540810
|
[5-[3-methylsulfonyl-5-[4-(trifluoromethyl)phenyl]phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C18H15F3N2O4S3
|
1
|
| 1 |
IC50 = 174 nM
|
|
|
|
CP0426810
|
[4-[3-ethyl-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C16H18N4O2S2
|
3
|
| 1 |
IC50 = 176 nM
|
|
|
| 2 |
IC50 = 425 nM
|
|
|
| 3 |
IC50 = 1238 nM
|
|
|
|
CP0574563
|
[5-(3-methylsulfonylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C11H12N2O4S3
|
1
|
| 1 |
IC50 = 184 nM
|
|
|
|
CP0552032
|
[5-[3-(4-fluorophenyl)-5-methylsulfonylphenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C17H15FN2O4S3
|
1
|
| 1 |
IC50 = 192 nM
|
|
|
|
CP0439961
|
[5-(3-methylsulfonyl-5-phenylphenyl)sulfanyl-1,3-thiazol-2-yl]methanamine
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|
C17H16N2O2S3
|
1
|
| 1 |
IC50 = 233 nM
|
|
|
|
CP0543929
|
[5-(3-methylsulfonyl-5-phenylphenyl)sulfinyl-1,3-thiazol-2-yl]methanamine
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|
C17H16N2O3S3
|
1
|
| 1 |
IC50 = 236 nM
|
|
|
|
CP0528275
|
[5-(3-methoxy-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C17H16N2O3S2
|
1
|
| 1 |
IC50 = 255 nM
|
|
|
|
CP0533666
|
[5-[3-(1-methylpyrazol-4-yl)-5-(trifluoromethyl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C15H13F3N4O2S2
|
1
|
| 1 |
IC50 = 259 nM
|
|
|
|
CP0426603
|
[5-[3-chloro-5-(1-methylpyrazol-4-yl)phenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C14H13ClN4O2S2
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0543928
|
[5-(benzenesulfonyl)-1,3-thiazol-2-yl]methanamine
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|
C10H10N2O2S2
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0437920
|
[5-(3-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C16H14N2O2S2
|
1
|
| 1 |
IC50 = 342 nM
|
|
|
|
CP0531009
|
[5-(3-phenyl-5-propan-2-ylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C19H20N2O2S2
|
1
|
| 1 |
IC50 = 343 nM
|
|
|
|
CP0349042
|
[5-(3-ethyl-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
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|
C18H18N2O2S2
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0488035
|
[5-(3-methylsulfonylphenyl)-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C11H12N2O2S2
|
1
|
| 1 |
IC50 = 394 nM
|
|
|
|
CP0564681
|
3-[[2-(aminomethyl)-1,3-thiazol-5-yl]sulfonyl]-N-methyl-5-phenylaniline
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|
C17H17N3O2S2
|
1
|
| 1 |
IC50 = 397 nM
|
|
|
|
CP0560732
|
[5-[3-(4-methylphenyl)-4-methylsulfonylphenyl]sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C18H18N2O4S3
|
1
|
| 1 |
IC50 = 423 nM
|
|
|
|
CP0224800
|
(5-naphthalen-2-ylsulfonylthiophen-2-yl)methanamine
Show/Hide
|
C15H13NO2S2
|
3
|
| 1 |
IC50 = 470 nM
|
|
|
| 2 |
IC50 = 810 nM
|
|
|
| 3 |
IC50 = 3400 nM
|
|
|
|
CP0556619
|
(5-propylsulfonyl-1,3-thiazol-2-yl)methanamine
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|
C7H12N2O2S2
|
1
|
| 1 |
IC50 = 554 nM
|
|
|
|
CP0437918
|
(5-cyclohexylsulfonyl-1,3-thiazol-2-yl)methanamine
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|
C10H16N2O2S2
|
1
|
| 1 |
IC50 = 606 nM
|
|
|
|
CP0528273
|
[5-(3-methylsulfonyl-5-phenylphenyl)-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C17H16N2O2S2
|
1
|
| 1 |
IC50 = 652 nM
|
|
|
|
CP0530343
|
[3-fluoro-5-(3-methylsulfonyl-5-phenylphenyl)sulfonylthiophen-2-yl]methanamine
Show/Hide
|
C18H16FNO4S3
|
1
|
| 1 |
IC50 = 671 nM
|
|
|
|
CP0574562
|
[5-[3-(4-methylphenyl)-4-methylsulfonylphenyl]sulfonylthiophen-2-yl]methanamine
Show/Hide
|
C19H19NO4S3
|
1
|
| 1 |
IC50 = 686 nM
|
|
|
|
CP0562505
|
(4-naphthalen-2-ylsulfonyl-1,3-thiazol-2-yl)methanamine
Show/Hide
|
C14H12N2O2S2
|
1
|
| 1 |
IC50 = 828 nM
|
|
|
|
CP0396640
|
(4Z)-4-(1-ethylquinolin-2-ylidene)-2-phenyl-5-phenyliminopyrazolidin-3-one
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|
C26H22N4O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0528274
|
[5-(3-tert-butyl-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C20H22N2O2S2
|
1
|
| 1 |
IC50 = 1040 nM
|
|
|
|
CP0528272
|
[5-(3-phenylphenyl)-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C16H14N2S
|
1
|
| 1 |
IC50 = 1596 nM
|
|
|
|
CP0390004
|
4,5-dimethyl-2-phenyl-4H-pyrazol-3-one
Show/Hide
|
C11H12N2O
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0440370
|
[3-chloro-5-(3-methylsulfonyl-5-phenylphenyl)sulfonylthiophen-2-yl]methanamine
Show/Hide
|
C18H16ClNO4S3
|
1
|
| 1 |
IC50 = 2164 nM
|
|
|
|
CP0437916
|
(2-naphthalen-2-ylsulfonyl-1,3-thiazol-5-yl)methanamine
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|
C14H12N2O2S2
|
3
|
| 1 |
IC50 = 3190 nM
|
|
|
| 2 |
IC50 = 6020 nM
|
|
|
| 3 |
IC50 = 26800 nM
|
|
|
|
CP0415596
|
6-(2,5-dimethylfuran-3-yl)-2-phenyl-1H-pyrazolo[3,4-b]pyridin-3-one
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|
C18H15N3O2
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0396642
|
2-phenyl-6-thiophen-2-yl-1H-pyrazolo[3,4-b]pyridin-3-one
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|
C16H11N3OS
|
1
|
| 1 |
IC50 = 7800 nM
|
|
|
|
CP0415597
|
1-hydroxypyridine-2-thione
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|
C5H5NOS
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0229574
|
4,6-dimethyl-2-phenyl-1H-pyrazolo[3,4-b]pyridin-3-one
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|
C14H13N3O
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0415598
|
6-methyl-3-[2-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylidene]hydrazinyl]-4H-1,2,4-triazin-5-one
Show/Hide
|
C15H15N7O2
|
1
|
| 1 |
IC50 = 34000 nM
|
|
|
|
CP0390003
|
6-(2-methoxyphenyl)-2-phenyl-1,7-dihydropyrazolo[3,4-b]pyridine-3,4-dione
Show/Hide
|
C19H15N3O3
|
1
|
| 1 |
IC50 = 45000 nM
|
|
|
|
CP0562029
|
N-methyl-1-[5-(3-methylsulfonyl-5-phenylphenyl)sulfonyl-1,3-thiazol-2-yl]methanamine
Show/Hide
|
C18H18N2O4S3
|
1
|
| 1 |
IC50 = 68260 nM
|
|
|
|
CP0196902
|
3-phenyl-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-4-one
Show/Hide
|
C13H9N3OS
|
1
|
| 1 |
IC50 = 75000 nM
|
|
|
|
CP0396641
|
5-tert-butyl-2-phenyl-4H-pyrazol-3-one
Show/Hide
|
C13H16N2O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0457811
|
diethyl 5-[(5-amino-3-oxo-2-phenyl-1H-pyrazol-4-yl)diazenyl]-3-methylthiophene-2,4-dicarboxylate
Show/Hide
|
C20H21N5O5S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
