| Compound ID |
Compound Name |
Compound Formula |
|
CP0057346
|
3-(2-aminopropyl)-1H-indol-5-ol
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|
C11H14N2O
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0499026
|
10-[3-(4-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C19H20FN5O
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0001238
|
14C-5-hydroxy tryptamine creatinine disulfate
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|
C10H12N2O
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
EC50 = 47 nM
|
|
|
|
CP0394858
|
10-[3-(3-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C19H20FN5O
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0394691
|
10-[3-(3-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0407685
|
10-[3-(Pyridin-3-yloxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C18H20N6O
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0439393
|
N-ethyl-2,6,7,12-tetrazatricyclo[7.5.0.03,7]tetradeca-1,3,5,8-tetraen-8-amine
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|
C12H17N5
|
1
|
| 1 |
EC50 = 138 nM
|
|
|
|
CP0426448
|
10-Piperidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C15H21N5
|
1
|
| 1 |
EC50 = 585 nM
|
|
|
|
CP0394689
|
10-[3-(2-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C19H20FN5O
|
1
|
| 1 |
EC50 = 648 nM
|
|
|
|
CP0394687
|
5-[1-(6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]inden-10-yl)-azetidin-3-yloxy]-1,3-dihydro-indol-2-one
Show/Hide
|
C21H22N6O2
|
1
|
| 1 |
EC50 = 762 nM
|
|
|
|
CP0468202
|
10-[3-(Pyridin-4-yloxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C18H20N6O
|
1
|
| 1 |
EC50 = 1227 nM
|
|
|
|
CP0394864
|
N-methyl-N-[4-[1-(2,6,7,12-tetrazatricyclo[7.5.0.03,7]tetradeca-1,3,5,8-tetraen-8-yl)azetidin-3-yl]oxyphenyl]acetamide
Show/Hide
|
C22H26N6O2
|
1
|
| 1 |
EC50 = 2046 nM
|
|
|
|
CP0407618
|
10-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C14H19N5
|
1
|
| 1 |
EC50 = 2310 nM
|
|
|
|
CP0426449
|
10-Azetidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C13H17N5
|
1
|
| 1 |
EC50 = 2348 nM
|
|
|
|
CP0407617
|
10-[3-(4-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
EC50 = 2634 nM
|
|
|
|
CP0439382
|
10-[3-(2-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
EC50 = 2676 nM
|
|
|
|
CP0407686
|
10-[3-(Pyridin-2-yloxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene
Show/Hide
|
C18H20N6O
|
1
|
| 1 |
EC50 = 5165 nM
|
|
|
|
CP0470834
|
10-(3-Phenoxy-azetidin-1-yl)-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraazacyclohepta[f]indene
Show/Hide
|
C19H21N5O
|
1
|
| 1 |
EC50 = 7774 nM
|
|
|
|
CP0432152
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
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|
C24H30N4O2S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 31.75 nM
|
|
|
|
CP0000753
|
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S,3R)-2-[[(2S)-2-(hexadecanoylamino)-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxamide
Show/Hide
|
C88H137N17O18
|
2
|
| 1 |
EC50 > 30000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0191883
|
(R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(trifluoromethyl)phenoxy)methyl)pyrimidin-4(3H)-one
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|
C18H21F3N4O2
|
1
|
| 1 |
EC50 > 1500 nM
|
|
|
|
CP0041613
|
Anapriline
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|
C16H21NO2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0066236
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-8-yl)oxy]propan-2-ol
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|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0366351
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-5-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0447670
|
N-(cyclohexylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C30H38FN3O2S
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0543621
|
1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2,2,2-trifluoroethoxy)phenyl]methyl]urea
Show/Hide
|
C22H26F4N4O2
|
1
|
| 1 |
IC50 = 0.54 nM
|
|
|
|
CP0477664
|
N-(cyclohexylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]naphthalene-2-sulfonamide
Show/Hide
|
C30H39N3O2S
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0940057
|
N-(1-ethylcyclopentyl)-7-(4-fluorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C18H24FN3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0778103
|
7-(2,4-difluorophenyl)-N-(1-ethylcyclopentyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C18H23F2N3
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0917881
|
N-(2-cyclobutylpropan-2-yl)-7-(2,4-difluorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C18H23F2N3
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0782717
|
7-(4-fluorophenyl)-N-(3-methylpentan-3-yl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C17H24FN3
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0918245
|
7-(4-fluorophenyl)-N-(1-methylcyclohexyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C18H24FN3
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0571640
|
3-[[4-(3-fluoropropoxy)phenyl]methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C23H30F2N4O2
|
1
|
| 1 |
IC50 = 1.93 nM
|
|
|
|
CP0912053
|
2-Benzyl-N-(4-fluorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H22ClFN4
|
1
|
| 1 |
IC50 = 1.95 nM
|
|
|
|
CP0552025
|
1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(propan-2-yloxymethyl)phenyl]methyl]urea
Show/Hide
|
C24H33FN4O2
|
1
|
| 1 |
IC50 = 2.05 nM
|
|
|
|
CP0571636
|
3-[[4-(2-fluoroethoxy)phenyl]methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C22H28F2N4O2
|
1
|
| 1 |
IC50 = 2.11 nM
|
|
|
|
CP0554502
|
3-[[4-(2,2-difluoroethoxy)phenyl]methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C22H27F3N4O2
|
1
|
| 1 |
IC50 = 2.17 nM
|
|
|
|
CP0544065
|
3-[[4-(4-fluorobutoxy)phenyl]methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C24H32F2N4O2
|
1
|
| 1 |
IC50 = 2.35 nM
|
|
|
|
CP0846855
|
N-(2-methyl-1-phenylpropan-2-yl)-7-p-tolyl-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C22H27N3
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0514881
|
N-(cyclohexylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]naphthalene-1-sulfonamide
Show/Hide
|
C30H39N3O2S
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0724162
|
2-Benzyl-N-phenyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H23ClN4
|
1
|
| 1 |
IC50 = 2.69 nM
|
|
|
|
CP0674236
|
2-Benzyl-N-(3-chlorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H22Cl2N4
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0544066
|
3-[[4-(2-fluoro-2-methylpropoxy)phenyl]methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C24H32F2N4O2
|
1
|
| 1 |
IC50 = 3.13 nM
|
|
|
|
CP0510691
|
N-(cyclohexylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-4-methoxybenzenesulfonamide
Show/Hide
|
C27H38FN3O3S
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0571639
|
3-[(2,2-dimethyl-3H-1-benzofuran-5-yl)methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C24H31FN4O2
|
1
|
| 1 |
IC50 = 3.49 nM
|
|
|
|
CP0853401
|
N-(1-ethylcyclopentyl)-7-(2-fluorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C18H24FN3
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0668809
|
7-(2,4-difluorophenyl)-N-(3-ethylpentan-3-yl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C18H25F2N3
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0568895
|
1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(4,4,4-trifluorobutoxy)phenyl]methyl]urea
Show/Hide
|
C24H30F4N4O2
|
1
|
| 1 |
IC50 = 3.78 nM
|
|
|
|
CP0939182
|
7-(2-fluorophenyl)-N-(2-methyl-1-phenylpropan-2-yl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C21H24FN3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0244731
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(4-fluorophenyl)-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C31H31Cl2FN4O
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0401996
|
N-(cyclohexylmethyl)-4-nitro-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
|
C26H36N4O4S
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0571641
|
3-[[4-(4,4-difluorobutoxy)phenyl]methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C24H31F3N4O2
|
1
|
| 1 |
IC50 = 4.29 nM
|
|
|
|
CP0577079
|
3-[[4-(3,3-difluoropropoxy)phenyl]methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C23H29F3N4O2
|
1
|
| 1 |
IC50 = 4.64 nM
|
|
|
|
CP0575888
|
1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(3,3,3-trifluoropropoxy)phenyl]methyl]urea
Show/Hide
|
C23H28F4N4O2
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0673445
|
2-Benzyl-N-(3-fluorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C21H22ClFN4
|
1
|
| 1 |
IC50 = 4.92 nM
|
|
|
|
CP0371721
|
N-(cyclohexylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
|
C29H37FN4O2S
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0858683
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl6N5O2
|
1
|
| 1 |
IC50 = 5.17 nM
|
|
|
|
CP0532670
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-5-methyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C28H35Cl2N5O2
|
1
|
| 1 |
IC50 = 5.17 nM
|
|
|
|
CP0510686
|
N-[4-[4-(4-fluorophenyl)piperazin-1-yl]butan-2-yl]naphthalene-2-sulfonamide
Show/Hide
|
C24H28FN3O2S
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0577204
|
1-[(5-fluoropyridin-2-yl)methyl]-3-[[3-fluoro-4-(2,2,2-trifluoroethoxy)phenyl]methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C22H25F5N4O2
|
1
|
| 1 |
IC50 = 6.86 nM
|
|
|
|
CP0522007
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-(4-fluorophenyl)-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C33H37FN4O
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0502602
|
N-(cyclohexylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C27H36F3N3O2S
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
|
CP0492830
|
N-(cyclohexylmethyl)-N-[3-[4-(3,4-dichlorophenyl)piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
|
C29H36Cl2N4O2S
|
1
|
| 1 |
IC50 = 7.7 nM
|
|
|
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CP0510369
|
N-(cyclopropylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
|
C26H31FN4O2S
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
|
CP0852994
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H35Cl6N5O3
|
1
|
| 1 |
IC50 = 8.63 nM
|
|
|
|
CP0434338
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C27H31Cl2N5O3
|
1
|
| 1 |
IC50 = 8.63 nM
|
|
|
|
CP0546972
|
1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
|
C24H33FN4O2
|
1
|
| 1 |
IC50 = 8.64 nM
|
|
|
|
CP0429608
|
ACP-103
Show/Hide
|
C25H34FN3O2
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 27.3 nM
|
|
|
|
CP0857451
|
N-(3-methoxyphenyl)-6-(4-methylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C17H21N7O
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
|
CP0421573
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)benzenesulfonamide
Show/Hide
|
C24H28FN3O4S
|
1
|
| 1 |
IC50 = 9.3 nM
|
|
|
|
CP0502603
|
N-(cyclohexylmethyl)-4-methoxy-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
|
C27H39N3O3S
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
|
CP0919600
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
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C27H35Cl6N5O4
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1
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| 1 |
IC50 = 9.86 nM
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CP0473479
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
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C27H31Cl2N5O4
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1
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| 1 |
IC50 = 9.86 nM
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CP0568896
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1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[(2-propan-2-yl-2,3-dihydro-1-benzofuran-5-yl)methyl]urea
Show/Hide
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C25H33FN4O2
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1
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| 1 |
IC50 = 9.98 nM
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CP0382888
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N-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
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C28H36N4O
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1
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| 1 |
IC50 = 10 nM
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CP0903271
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
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C26H35Cl6N5O2
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1
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| 1 |
IC50 = 10.3 nM
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CP0443120
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(2-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
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C26H31Cl2N5O2
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1
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| 1 |
IC50 = 10.3 nM
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CP0892125
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N-tert-butyl-7-(2,4-difluorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C15H19F2N3
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1
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| 1 |
IC50 = 11 nM
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CP0939181
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N-tert-butyl-7-p-tolyl-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C16H23N3
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1
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| 1 |
IC50 = 11 nM
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CP0055933
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3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
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C22H22FN3O3
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2
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| 1 |
IC50 = 11 nM
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| 2 |
IC50 = 80 nM
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CP0421575
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4-cyano-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)benzenesulfonamide
Show/Hide
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C25H27FN4O4S
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1
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| 1 |
IC50 = 11.3 nM
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CP0430835
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N-(cyclohexylmethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C31H41N3O3S
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1
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| 1 |
IC50 = 11.6 nM
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CP0424879
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-propan-2-ylbenzamide
Show/Hide
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C25H30FN3O2
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1
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| 1 |
IC50 = 11.6 nM
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CP0464923
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US8835436, Example 103
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C28H36ClN5O
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1
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| 1 |
IC50 = 12 nM
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CP0577601
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3-[[3-bromo-4-(2,2,2-trifluoroethoxy)phenyl]methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
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C22H25BrF4N4O2
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1
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| 1 |
IC50 = 12 nM
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CP0917395
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C31H36Cl4FN5O
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1
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| 1 |
IC50 = 12.2 nM
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CP0775801
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5-((1H-1,2,4-Triazol-1-yl)methyl)-N-(3-(4-(3-chloro-2-methylphenyl)piperazin-1-yl)propyl)-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C33H38Cl4N8O
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1
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| 1 |
IC50 = 12.3 nM
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CP0373567
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N-[4-(4-phenylpiperazin-1-yl)butan-2-yl]naphthalene-2-sulfonamide
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C24H29N3O2S
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1
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| 1 |
IC50 = 12.7 nM
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CP0930888
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl4N5O2
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1
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| 1 |
IC50 = 12.8 nM
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CP0486579
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N-[3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]propyl]-1-(2-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
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C27H34ClN5O2
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1
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| 1 |
IC50 = 12.8 nM
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CP0858684
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C31H37Cl6N5O2
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1
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| 1 |
IC50 = 13 nM
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CP0502301
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N-(cyclohexylmethyl)-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C31H38F3N3O2S
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1
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| 1 |
IC50 = 13.1 nM
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CP0528543
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N-(cyclohexylmethyl)-4-fluoro-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
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C26H36FN3O2S
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1
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| 1 |
IC50 = 13.2 nM
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CP0871154
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1,2-diphenyl-1Himidazole-4-carboxamide dihydrochloride
Show/Hide
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C31H37Cl2N5O
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1
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| 1 |
IC50 = 13.2 nM
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CP0751540
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C31H37Cl4N5O
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1
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| 1 |
IC50 = 13.9 nM
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CP0940055
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N-tert-butyl-7-(2-fluoro-4-methylphenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C16H22FN3
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1
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| 1 |
IC50 = 14 nM
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CP0894532
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide Dihydrochloride
Show/Hide
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C30H35Cl6N5O
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1
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| 1 |
IC50 = 14.2 nM
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CP0897814
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7-(2-fluorophenyl)-N-(3-methylpentan-3-yl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C17H24FN3
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1
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| 1 |
IC50 = 14.5 nM
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CP0543618
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1-[(6-fluoropyridazin-3-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
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C23H32FN5O2
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1
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| 1 |
IC50 = 14.7 nM
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CP0699448
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N-(3-methylpentan-3-yl)-7-p-tolyl-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C18H27N3
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1
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| 1 |
IC50 = 14.9 nM
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CP0424886
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4-fluoro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)benzenesulfonamide
Show/Hide
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C24H27F2N3O4S
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1
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| 1 |
IC50 = 15.1 nM
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CP0847153
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C29H41Cl4N5O2
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1
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| 1 |
IC50 = 15.2 nM
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CP0515714
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N-[3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-5-methyl-2-propylimidazole-4-carboxamide
Show/Hide
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C29H38ClN5O2
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1
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| 1 |
IC50 = 15.2 nM
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CP0409927
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US8835436, Example 113
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C28H37N5O
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1
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| 1 |
IC50 = 16 nM
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CP0430832
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N-(cyclohexylmethyl)-4-methoxy-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]benzenesulfonamide
Show/Hide
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C28H41N3O4S
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1
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| 1 |
IC50 = 16.3 nM
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CP0908964
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C25H32Cl6FN5O
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1
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| 1 |
IC50 = 16.8 nM
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CP0414724
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(2-fluorophenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
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C25H28Cl2FN5O
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1
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| 1 |
IC50 = 16.8 nM
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CP0497140
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-N,2-dimethyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
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C31H42N4O
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1
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| 1 |
IC50 = 17 nM
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CP0571642
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3-[(2,2-dimethylchromen-6-yl)methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
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C25H31FN4O2
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1
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| 1 |
IC50 = 17.27 nM
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CP0846051
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N-(4-fluorophenyl)-6-(4-(4-fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C21H19F2N7
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1
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| 1 |
IC50 = 17.9 nM
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CP0940012
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N-tert-butyl-7-(2-fluorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C15H20FN3
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1
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| 1 |
IC50 = 18 nM
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CP0577202
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1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(3,3,3-trifluoropropyl)phenyl]methyl]urea
Show/Hide
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C23H28F4N4O
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1
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| 1 |
IC50 = 18.3 nM
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CP0673546
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C25H33Cl6N5O
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1
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| 1 |
IC50 = 18.6 nM
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CP0402995
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2,5-dimethyl-1-phenylimidazole-4-carboxamide
Show/Hide
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C25H29Cl2N5O
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1
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| 1 |
IC50 = 18.6 nM
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CP0552795
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)benzamide
Show/Hide
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C25H28FN3O3
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1
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| 1 |
IC50 = 18.8 nM
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CP0373060
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N-[3-[4-(3,4-dichlorophenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C23H25Cl2N3O2S
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1
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| 1 |
IC50 = 19 nM
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CP0847156
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1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C34H41Cl2N5O3
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1
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| 1 |
IC50 = 19 nM
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CP0857566
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C32H39Cl2N5O2
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1
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| 1 |
IC50 = 19 nM
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CP0420028
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-2-phenylimidazole-4-carboxamide
Show/Hide
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C32H37N5O2
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1
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| 1 |
IC50 = 19 nM
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CP0373407
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N-(cyclohexylmethyl)-4-methoxy-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]benzenesulfonamide
Show/Hide
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C28H38F3N3O3S
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1
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| 1 |
IC50 = 19.5 nM
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CP0911229
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C30H34Cl6FN5O
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1
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| 1 |
IC50 = 19.5 nM
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CP0871159
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-chlorophenyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl6N5O
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1
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| 1 |
IC50 = 20 nM
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CP0910744
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C26H35Cl6N5O2
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1
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| 1 |
IC50 = 20 nM
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CP0486576
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
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C26H31Cl2N5O2
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1
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| 1 |
IC50 = 20 nM
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CP0875068
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(S)-N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C31H36Cl4FN5O2
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1
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| 1 |
IC50 = 20.1 nM
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CP0420202
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N-[(2S)-3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(4-fluorophenyl)-5-methyl-2-phenylimidazole-4-carboxamide
Show/Hide
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C31H33ClFN5O2
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1
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| 1 |
IC50 = 20.1 nM
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CP0568897
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1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[(2-propan-2-yl-1-benzofuran-5-yl)methyl]urea
Show/Hide
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C25H31FN4O2
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1
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| 1 |
IC50 = 20.9 nM
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CP0824248
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N-tert-butyl-7-(4-fluorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C15H20FN3
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1
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| 1 |
IC50 = 21 nM
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CP0844939
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-(pyridin-2-yl)-1H-pyrrole-3-carboxamide dihydrochloride
Show/Hide
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C24H31Cl6N5O
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1
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| 1 |
IC50 = 21 nM
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CP0858682
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-5-methyl-1-phenyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl6N5O
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1
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| 1 |
IC50 = 21 nM
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CP0887878
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H39Cl4N5O2
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1
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| 1 |
IC50 = 21 nM
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CP0894534
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H36Cl6FN5O
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1
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| 1 |
IC50 = 21 nM
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CP0415720
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-5-methyl-1-phenyl-2-propylimidazole-4-carboxamide
Show/Hide
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C27H33Cl2N5O
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1
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| 1 |
IC50 = 21 nM
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CP0577200
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3-[(2,2-dimethyl-3,4-dihydrochromen-6-yl)methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
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C25H33FN4O2
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1
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| 1 |
IC50 = 21.25 nM
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CP0406099
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N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
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C26H31FN4O
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1
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| 1 |
IC50 = 22 nM
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CP0382793
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N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1-(4-fluorophenyl)-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
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C31H32ClFN4O
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1
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| 1 |
IC50 = 22.9 nM
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CP0527405
|
US8835436, Example 114
Show/Hide
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C26H32FN5O
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1
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| 1 |
IC50 = 23 nM
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CP0871051
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl4N5O2
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1
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| 1 |
IC50 = 23.1 nM
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CP0402822
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N-[3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
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C27H34ClN5O2
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1
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| 1 |
IC50 = 23.1 nM
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CP0852998
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C33H41Cl2N5O2
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1
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| 1 |
IC50 = 24 nM
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CP0871027
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H35Cl6N5O2
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1
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| 1 |
IC50 = 24 nM
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CP0402819
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-methyl-1,2-diphenylimidazole-4-carboxamide
Show/Hide
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C30H31Cl2N5O2
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1
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| 1 |
IC50 = 24 nM
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CP0846048
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N-(4-fluorophenyl)-6-(4-methylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C16H18FN7
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1
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| 1 |
IC50 = 24.2 nM
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CP0861033
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2,4-dimethyl-5-phenyl-1-propyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C28H35Cl3N4O
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1
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| 1 |
IC50 = 25 nM
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CP0846049
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6-(4-methylpiperazin-1-yl)-N-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C16H19N7
|
1
|
| 1 |
IC50 = 25.1 nM
|
|
|
|
CP0891570
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C22H35Cl6N5O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0574469
|
1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropyl)phenyl]methyl]urea
Show/Hide
|
C24H33FN4O
|
1
|
| 1 |
IC50 = 26.4 nM
|
|
|
|
CP0847162
|
rac-N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C31H36Cl4FN5O2
|
1
|
| 1 |
IC50 = 26.7 nM
|
|
|
|
CP0858681
|
N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-2-ethyl-5-methyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H33Cl6N5O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0527457
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-2-ethyl-5-methyl-1-phenylimidazole-4-carboxamide
Show/Hide
|
C25H29Cl2N5O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0847879
|
N-(4-fluorophenyl)-6-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C21H20FN7
|
1
|
| 1 |
IC50 = 27.2 nM
|
|
|
|
CP0543620
|
1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2,2,2-trifluoroethoxy)-3-(trifluoromethyl)phenyl]methyl]urea
Show/Hide
|
C23H25F7N4O2
|
1
|
| 1 |
IC50 = 27.3 nM
|
|
|
|
CP0871052
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H38Cl2FN5O
|
1
|
| 1 |
IC50 = 27.8 nM
|
|
|
|
CP0390407
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C27H32Cl2N4O
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0871160
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H37Cl4N5O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0876522
|
N-(4-chlorophenyl)-6-(4-methylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C16H18ClN7
|
1
|
| 1 |
IC50 = 28.8 nM
|
|
|
|
CP0853000
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2-chlorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0420234
|
US8835436, Example 115
Show/Hide
|
C27H33N5O3
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0497110
|
N-(cyclohexylmethyl)-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
|
C30H37F3N4O2S
|
1
|
| 1 |
IC50 = 29.1 nM
|
|
|
|
CP0857563
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H39Cl2N5O
|
1
|
| 1 |
IC50 = 29.4 nM
|
|
|
|
CP0891571
|
1-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H33Cl8N5O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0413785
|
US8835436, Example 11
Show/Hide
|
C25H28Cl3N5O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0668069
|
N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-2,5-dimethyl-1-phenyl-1Himidazole-4-carboxamide dihydrochloride
Show/Hide
|
C24H31Cl6N5O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0857567
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H40Cl2FN5O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0412633
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-2,5-dimethyl-1-phenylimidazole-4-carboxamide
Show/Hide
|
C24H27Cl2N5O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0894640
|
1-(3,5-Dimethoxyphenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl2N5O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0422518
|
1-(3,5-dimethoxyphenyl)-N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C29H39N5O3
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0875090
|
1-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl4N5O
|
1
|
| 1 |
IC50 = 32.4 nM
|
|
|
|
CP0456781
|
1-(4-chlorophenyl)-N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2-propylimidazole-4-carboxamide
Show/Hide
|
C28H36ClN5O
|
1
|
| 1 |
IC50 = 32.4 nM
|
|
|
|
CP0861032
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1,2,4-trimethyl-5-phenyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C26H31Cl3N4O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0918850
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-N,2-dimethyl-5-phenyl-1-propyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C29H37Cl3N4O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0463160
|
US8835436, Example 147
Show/Hide
|
C28H37N5O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0571637
|
1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]methyl]urea
Show/Hide
|
C22H24F6N4O2
|
1
|
| 1 |
IC50 = 33.4 nM
|
|
|
|
CP0473460
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-1-propyl-5-pyridin-4-ylpyrrole-3-carboxamide
Show/Hide
|
C27H33Cl2N5O
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0430833
|
N-(cyclohexylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]quinoline-8-sulfonamide
Show/Hide
|
C29H38N4O2S
|
1
|
| 1 |
IC50 = 34.6 nM
|
|
|
|
CP0483490
|
4-chloro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)benzenesulfonamide
Show/Hide
|
C24H27ClFN3O4S
|
1
|
| 1 |
IC50 = 34.6 nM
|
|
|
|
CP0744599
|
N-tert-butyl-7-phenyl-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C15H21N3
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0918740
|
N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-6-phenylpyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C25H28Cl3N5O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0426880
|
N-(cyclopropylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H33N3O2S
|
1
|
| 1 |
IC50 = 35.9 nM
|
|
|
|
CP0497500
|
5-tert-Butyl-N-(2-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C25H38N4O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0912473
|
N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-2,4-dimethyl-5-phenyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C25H29Cl3N4O
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0847154
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H34Cl4FN5O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0422033
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-pyridin-4-ylpyrrole-3-carboxamide
Show/Hide
|
C25H29Cl2N5O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0513546
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N,1,2-trimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C27H32Cl2N4O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0912474
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2,4-dimethyl-5-phenyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C26H31Cl3N4O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0904461
|
N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-5-methyl-1-phenyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0429821
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-5-methyl-1-phenyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C26H31Cl2N5O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0224658
|
8-chloro-7-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H26ClFN2O4
|
1
|
| 1 |
IC50 = 39.2 nM
|
|
|
|
CP0373838
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C24H26Cl2N4O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0917394
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H34Cl4FN5O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0390294
|
N-[3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]propyl]-1-(2-fluorophenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C26H31ClFN5O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0725663
|
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H39Cl2N5O3
|
1
|
| 1 |
IC50 = 40.6 nM
|
|
|
|
CP0531998
|
N-(cyclopropylmethyl)-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]benzamide
Show/Hide
|
C26H30FN3O2
|
1
|
| 1 |
IC50 = 40.8 nM
|
|
|
|
CP0916425
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1,2-dimethyl-5-(pyridin-2-yl)-1H-pyrrole-3-carboxamide dihydrochloride
Show/Hide
|
C25H33Cl6N5O
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0543622
|
1-[(3,5-difluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
|
C24H32F2N4O2
|
1
|
| 1 |
IC50 = 43.2 nM
|
|
|
|
CP0903877
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-isobutyl-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C24H39Cl4N5O
|
1
|
| 1 |
IC50 = 45.5 nM
|
|
|
|
CP0418377
|
N-[3-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]propyl]-2,5-dimethyl-1-(2-methylpropyl)imidazole-4-carboxamide
Show/Hide
|
C24H36ClN5O
|
1
|
| 1 |
IC50 = 45.5 nM
|
|
|
|
CP0039201
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C26H30Cl2N4O
|
2
|
| 1 |
IC50 = 46 nM
|
|
|
| 2 |
IC50 = 46.2 nM
|
|
|
|
CP0372471
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-1-propyl-5-pyridin-3-ylpyrrole-3-carboxamide
Show/Hide
|
C27H33Cl2N5O
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0664262
|
N-(2-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethyl)-6-methyl-2-(methylthio)pyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C21H30ClN5OS
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0871161
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H41Cl4N5O3
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0922377
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2-ethyl-5-methyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0456760
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-ethyl-5-methyl-1-phenylimidazole-4-carboxamide
Show/Hide
|
C26H31Cl2N5O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0844940
|
5-tert-Butyl-N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C23H33Cl3N4O
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0417851
|
N-benzyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C28H29N3O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0430831
|
N-(cyclopropylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H32FN3O2S
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0853005
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O3
|
1
|
| 1 |
IC50 = 52.1 nM
|
|
|
|
CP0453995
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(2-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C26H31Cl2N5O3
|
1
|
| 1 |
IC50 = 52.1 nM
|
|
|
|
CP0880357
|
6-(4-benzylpiperazin-1-yl)-N-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C22H22FN7
|
1
|
| 1 |
IC50 = 52.2 nM
|
|
|
|
CP0916526
|
N-(3-(4-(3,4-Dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1-propyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C28H35Cl3N4O
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0845009
|
N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-6-methyl-2-(methylthio)pyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C22H32ClN5OS
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0851845
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H38Cl4FN5O
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0860116
|
N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-6-methyl-2-(methylthio)pyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C19H24Cl3N5OS
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0891617
|
1-Cyclopentyl-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C24H37Cl6N5O
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0871162
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl4N5O3
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0695796
|
SID50106634
Show/Hide
|
C21H28N2O3S3
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0373832
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0853002
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C31H37Cl4N5O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0857951
|
2-Benzyl-N-(4-methoxyphenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
|
C22H25ClN4O
|
1
|
| 1 |
IC50 = 57.4 nM
|
|
|
|
CP0916426
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-1-propyl-5-(pyridin-2-yl)-1H-pyrrole-3-carboxamide dihydrochloride
Show/Hide
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C27H37Cl6N5O
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1
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| 1 |
IC50 = 58 nM
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CP0887876
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1-(2-(trifluoromethyl)phenyl)-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C26H32Cl6F3N5O
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1
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| 1 |
IC50 = 58 nM
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CP0851847
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-5-methyl-1,2-diphenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C32H39Cl2N5O2
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1
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| 1 |
IC50 = 58.6 nM
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CP0389324
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-5-methyl-1,2-diphenylimidazole-4-carboxamide
Show/Hide
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C32H37N5O2
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1
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| 1 |
IC50 = 58.6 nM
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CP0430836
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N-(cyclohexylmethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
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C30H40N4O3S
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1
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| 1 |
IC50 = 59.9 nM
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CP0373841
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N-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
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C29H38N4O
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1
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| 1 |
IC50 = 61 nM
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CP0847152
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C28H39Cl2N5O2
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1
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| 1 |
IC50 = 62.7 nM
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CP0847158
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C28H39Cl6N5O3
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1
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| 1 |
IC50 = 63.1 nM
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CP0561515
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(4-methoxyphenyl)-5-methyl-2-propylimidazole-4-carboxamide
Show/Hide
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C28H35Cl2N5O3
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1
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| 1 |
IC50 = 63.1 nM
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CP0852999
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H36Cl2FN5O
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1
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| 1 |
IC50 = 64.8 nM
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CP0930892
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1-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl4N5O
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1
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| 1 |
IC50 = 67 nM
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CP0074515
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-piperidin-1-ylpyrrole-3-carboxamide
Show/Hide
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C30H37Cl2N5O
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1
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| 1 |
IC50 = 67.1 nM
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CP0575891
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1-[(5-fluoropyridin-2-yl)methyl]-3-[[4-(3-methylbutyl)phenyl]methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
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C25H35FN4O
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1
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| 1 |
IC50 = 67.2 nM
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CP0450109
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US8835436, Example 148
Show/Hide
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C28H37N5O2
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1
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| 1 |
IC50 = 68.2 nM
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CP0860117
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2-tert-butyl-N-(2-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethyl)-6-methylpyrimidine-4-carboxamide hydrochloride
Show/Hide
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C24H36ClN5O
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1
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| 1 |
IC50 = 69 nM
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CP0401343
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US8835436, Example 4
Show/Hide
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C25H28Cl3N5O
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1
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| 1 |
IC50 = 69 nM
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CP0373410
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N-(cyclopropylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
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C24H30F3N3O2S
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1
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| 1 |
IC50 = 70.8 nM
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CP0852997
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C30H43Cl2N5O2
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1
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| 1 |
IC50 = 70.8 nM
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CP0573741
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-(4-methoxyphenyl)-5-methyl-2-propylimidazole-4-carboxamide
Show/Hide
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C30H41N5O2
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1
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| 1 |
IC50 = 70.8 nM
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CP0875091
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1-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C26H35Cl8N5O
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1
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| 1 |
IC50 = 70.9 nM
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CP0472050
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US8835436, Example 2
Show/Hide
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C13H15N3
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1
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| 1 |
IC50 = 70.9 nM
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CP0846853
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N-tert-butyl-7-(2,4-dimethylphenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C17H25N3
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1
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| 1 |
IC50 = 71 nM
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CP0923410
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C32H38Cl2FN5O2
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1
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| 1 |
IC50 = 71 nM
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CP0452722
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N-(cyclopropylmethyl)-N-[3-[4-(4-fluorophenyl)piperazin-1-yl]propyl]-4-methoxybenzenesulfonamide
Show/Hide
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C24H32FN3O3S
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1
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| 1 |
IC50 = 72.5 nM
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CP0871165
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(R)-N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl2N5O2
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1
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| 1 |
IC50 = 72.5 nM
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CP0403437
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N-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-2,5-dimethyl-1-phenylimidazole-4-carboxamide
Show/Hide
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C27H35N5O2
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1
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| 1 |
IC50 = 72.5 nM
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CP0424877
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-propylbenzamide
Show/Hide
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C25H30FN3O2
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1
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| 1 |
IC50 = 73.1 nM
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CP0501817
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4-Methoxy-N-{3-[4-(p-fluorophenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide
Show/Hide
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C20H26FN3O3S
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1
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| 1 |
IC50 = 74 nM
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CP0373833
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-ethyl-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
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C29H38N4O
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1
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| 1 |
IC50 = 75 nM
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CP0371722
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N-(cyclopropylmethyl)-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
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C27H31F3N4O2S
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1
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| 1 |
IC50 = 75 nM
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CP0871152
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-5-methyl-1-phenyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C29H41Cl2N5O
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1
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| 1 |
IC50 = 75 nM
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CP0543617
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1-[1-[2-(dimethylamino)ethyl]piperidin-4-yl]-1-[(4-fluorophenyl)methyl]-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
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C28H41FN4O2
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1
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| 1 |
IC50 = 75.4 nM
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CP0846854
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N-tert-butyl-7-(2-chlorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C15H20ClN3
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1
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| 1 |
IC50 = 76 nM
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CP0500061
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4-butoxy-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
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C17H28N2O3S
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1
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| 1 |
IC50 = 77 nM
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CP0847160
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H36Cl2FN5O2
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1
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| 1 |
IC50 = 78.3 nM
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CP0853001
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1-(2-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl4N5O
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1
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| 1 |
IC50 = 80 nM
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CP0403000
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1-(2-chlorophenyl)-N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2,5-dimethylimidazole-4-carboxamide
Show/Hide
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C27H34ClN5O
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1
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| 1 |
IC50 = 80 nM
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CP0857562
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-cyclopentyl-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C25H39Cl4N5O
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1
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| 1 |
IC50 = 80.6 nM
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CP0673446
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2-Benzyl-N-(3-methoxyphenyl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine-4-amine hydrochloride
Show/Hide
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C22H25ClN4O
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1
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| 1 |
IC50 = 84.4 nM
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CP0259093
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C24H29N3O3S
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1
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| 1 |
IC50 = 85 nM
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CP0373571
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N-(cyclopropylmethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C28H35N3O3S
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1
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| 1 |
IC50 = 85.8 nM
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CP0416326
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N-(cyclopropylmethyl)-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
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C25H29N3O2S
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1
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| 1 |
IC50 = 88 nM
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CP0851846
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1-(2-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C29H41Cl4N5O
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1
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| 1 |
IC50 = 90 nM
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CP0852995
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl2N5O
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1
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| 1 |
IC50 = 91 nM
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CP0372469
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N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
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C26H31ClN4O
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1
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| 1 |
IC50 = 92 nM
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CP0373828
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N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1-ethyl-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
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C27H33ClN4O
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1
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| 1 |
IC50 = 92 nM
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CP0914751
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5-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
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C27H34Cl2N4O
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1
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| 1 |
IC50 = 92 nM
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CP0424881
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
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C25H27F4N3O4S
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1
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| 1 |
IC50 = 92.7 nM
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CP0847161
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C30H34Cl6FN5O2
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1
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| 1 |
IC50 = 94 nM
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CP0419082
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N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C24H26F3N3O2S
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1
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| 1 |
IC50 = 95 nM
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CP0871166
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(R)-N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C31H36Cl4FN5O2
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1
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| 1 |
IC50 = 95 nM
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CP0887879
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1-(3-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl4N5O
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1
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| 1 |
IC50 = 96.8 nM
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CP0441409
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US8835436, Example 112
Show/Hide
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C28H37N5O3
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1
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| 1 |
IC50 = 97 nM
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CP0912346
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-cyclopentyl-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C25H39Cl4N5O2
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1
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| 1 |
IC50 = 97.6 nM
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CP0373839
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
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C29H36Cl2N4O
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1
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| 1 |
IC50 = 104 nM
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CP0853010
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C25H32Cl6FN5O2
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1
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| 1 |
IC50 = 104 nM
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CP0914752
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5-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
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C25H28Cl4N4O
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1
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| 1 |
IC50 = 105 nM
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CP0852996
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-2-isopropyl-5-methyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C29H41Cl2N5O
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1
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| 1 |
IC50 = 105 nM
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CP0408305
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-5-methyl-1-phenyl-2-propan-2-ylimidazole-4-carboxamide
Show/Hide
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C29H39N5O
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1
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| 1 |
IC50 = 105 nM
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CP0857559
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N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C29H39Cl6N5O3
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1
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| 1 |
IC50 = 106 nM
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CP0861034
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5-tert-Butyl-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-propyl)-2-methyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
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C23H33Cl3N4O
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1
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| 1 |
IC50 = 107 nM
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CP0917398
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-chlorophenyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl6N5O2
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1
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| 1 |
IC50 = 107 nM
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CP0577037
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1-[3-(dimethylamino)cyclopentyl]-1-[(4-fluorophenyl)methyl]-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
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C26H36FN3O2
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1
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| 1 |
IC50 = 110.2 nM
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CP0904596
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N-tert-butyl-7-o-tolyl-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C16H23N3
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1
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| 1 |
IC50 = 112 nM
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CP0645882
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N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-6-isopropyl-2-methylpyrimidine-4-carboxamide Hydrochloride
Show/Hide
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C22H30Cl3N5O
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1
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| 1 |
IC50 = 113 nM
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CP0871158
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H36Cl2FN5O
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1
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| 1 |
IC50 = 117.9 nM
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CP0398640
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N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-2-sulfonamide
Show/Hide
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C24H29N3O2S
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1
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| 1 |
IC50 = 118 nM
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CP0398637
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N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-1-sulfonamide
Show/Hide
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C24H29N3O2S
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1
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| 1 |
IC50 = 122 nM
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CP0540384
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3-[[3-chloro-4-(2,2,2-trifluoroethoxy)phenyl]methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
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C22H25ClF4N4O2
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1
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| 1 |
IC50 = 125 nM
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CP0871028
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H43Cl2N5O3
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1
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| 1 |
IC50 = 126 nM
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CP0417821
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(4-methoxyphenyl)-5-methyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C30H41N5O3
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1
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| 1 |
IC50 = 126 nM
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CP0871164
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C28H37Cl4N5O4
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1
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| 1 |
IC50 = 127 nM
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CP0544499
|
US8835436, Example 90
Show/Hide
|
C33H36BrCl2N5O
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1
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| 1 |
IC50 = 127 nM
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CP0373834
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C30H40N4O
|
1
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| 1 |
IC50 = 129 nM
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CP0452562
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-piperidin-1-ylpyrrole-3-carboxamide
Show/Hide
|
C32H43N5O
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1
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| 1 |
IC50 = 133 nM
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CP0919010
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-phenyl-2-propyl-1Himidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl2N5O
|
1
|
| 1 |
IC50 = 133 nM
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CP0429646
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-phenyl-2-propylimidazole-4-carboxamide
Show/Hide
|
C28H37N5O
|
1
|
| 1 |
IC50 = 133 nM
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CP0473458
|
N-[3-[4-(2,5-difluorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C28H34F2N4O
|
1
|
| 1 |
IC50 = 135 nM
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CP0492831
|
N-(cyclopropylmethyl)-4-methoxy-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
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C24H33N3O3S
|
1
|
| 1 |
IC50 = 136 nM
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CP0403439
|
US8835436, Example 133
Show/Hide
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C30H31Cl2N5O3
|
1
|
| 1 |
IC50 = 137 nM
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CP0579474
|
1-[3-(dimethylamino)cyclobutyl]-1-[(4-fluorophenyl)methyl]-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
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C25H34FN3O2
|
1
|
| 1 |
IC50 = 138.8 nM
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CP0894533
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl6N5O2
|
1
|
| 1 |
IC50 = 139 nM
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CP0847155
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(4-fluorophenyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H38Cl2FN5O
|
1
|
| 1 |
IC50 = 141 nM
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CP0507696
|
N-(cyclopropylmethyl)-4-fluoro-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
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C23H30FN3O2S
|
1
|
| 1 |
IC50 = 142 nM
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CP0857564
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl2N5O2
|
1
|
| 1 |
IC50 = 144 nM
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CP0415700
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-1-(2-methoxyphenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C28H37N5O2
|
1
|
| 1 |
IC50 = 144 nM
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CP0875066
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1-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl4N5O2
|
1
|
| 1 |
IC50 = 147 nM
|
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CP0389365
|
US8835436, Example 111
Show/Hide
|
C28H36ClN5O2
|
1
|
| 1 |
IC50 = 147 nM
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CP0916528
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-1-ethyl-2-methyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C29H38Cl2N4O
|
1
|
| 1 |
IC50 = 151 nM
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CP0470731
|
N-[2-[4-(3-chloro-2-methylphenyl)piperazin-1-yl]ethyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C26H31ClN4O
|
1
|
| 1 |
IC50 = 152 nM
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CP0514205
|
N-[3-[4-(3-methoxyphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C29H38N4O2
|
1
|
| 1 |
IC50 = 153 nM
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|
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CP0912475
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-1-ethyl-2-methyl-1H-pyrrole-3-carboxamidehydrochloride
Show/Hide
|
C27H32Cl4N4O
|
1
|
| 1 |
IC50 = 153 nM
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CP0894626
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-5-methyl-1-phenyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl4N5O
|
1
|
| 1 |
IC50 = 154 nM
|
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CP0452116
|
4-iodo-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C13H19IN2O2S
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0399042
|
N-methyl-N-(1-methylpiperidin-4-yl)-4-propan-2-ylbenzenesulfonamide
Show/Hide
|
C16H26N2O2S
|
1
|
| 1 |
IC50 = 161 nM
|
|
|
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CP0497501
|
5-tert-butyl-N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1,2-dimethylpyrrole-3-carboxamide
Show/Hide
|
C24H34Cl2N4O
|
1
|
| 1 |
IC50 = 163 nM
|
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CP0847878
|
2-(4-(4-(4-fluorophenylamino)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)piperazin-1-yl)ethanol
Show/Hide
|
C17H20FN7O
|
1
|
| 1 |
IC50 = 163 nM
|
|
|
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CP0817944
|
N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2,6-dimethylpyrimidine-4-carboxamide Hydrochloride
Show/Hide
|
C20H26Cl3N5O
|
1
|
| 1 |
IC50 = 166 nM
|
|
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CP0853008
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C32H39Cl4N5O3
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0447686
|
N-(cyclopropylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]naphthalene-1-sulfonamide
Show/Hide
|
C27H33N3O2S
|
1
|
| 1 |
IC50 = 171 nM
|
|
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|
CP0871156
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl4N5O2
|
1
|
| 1 |
IC50 = 171 nM
|
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CP0417858
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylbenzenesulfonamide
Show/Hide
|
C20H27N3O2S
|
1
|
| 1 |
IC50 = 172 nM
|
|
|
|
CP0853006
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl2N5O3
|
1
|
| 1 |
IC50 = 174.9 nM
|
|
|
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CP0428964
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C25H28Cl2N4O
|
1
|
| 1 |
IC50 = 175 nM
|
|
|
|
CP0903799
|
N-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-1-ethyl-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C25H29Cl3N4O
|
1
|
| 1 |
IC50 = 175 nM
|
|
|
|
CP0847164
|
1-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl8N5O2
|
1
|
| 1 |
IC50 = 176.6 nM
|
|
|
|
CP0373830
|
1-benzyl-N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C32H35ClN4O
|
1
|
| 1 |
IC50 = 179 nM
|
|
|
|
CP0371728
|
N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butan-2-yl]naphthalene-2-sulfonamide
Show/Hide
|
C25H28F3N3O2S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0415113
|
N-(cyclopropylmethyl)-4-nitro-N-[3-(4-phenylpiperazin-1-yl)propyl]benzenesulfonamide
Show/Hide
|
C23H30N4O4S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
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CP0894623
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(3-chlorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H35Cl6N5O2
|
1
|
| 1 |
IC50 = 182.1 nM
|
|
|
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CP0871163
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-5-methyl-2-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C33H41Cl2N5O3
|
1
|
| 1 |
IC50 = 185 nM
|
|
|
|
CP0382791
|
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C28H35ClN4O
|
1
|
| 1 |
IC50 = 191 nM
|
|
|
|
CP0916529
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methyl-1-propyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C30H40Cl2N4O
|
1
|
| 1 |
IC50 = 192 nM
|
|
|
|
CP0919599
|
N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H36Cl6FN5O2
|
1
|
| 1 |
IC50 = 196 nM
|
|
|
|
CP0871029
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H34Cl4FN5O2
|
1
|
| 1 |
IC50 = 197 nM
|
|
|
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CP0917330
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-5-methyl-1-phenyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C28H39Cl4N5O2
|
1
|
| 1 |
IC50 = 201 nM
|
|
|
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CP0853009
|
1-(3,4-Dimethoxyphenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl2N5O4
|
1
|
| 1 |
IC50 = 204.5 nM
|
|
|
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CP0379359
|
N'-[(E)-[1-(4-methoxyphenyl)sulfonyl-4-nitroindol-3-yl]methylideneamino]-N,N-dimethylmethanimidamide
Show/Hide
|
C19H19N5O5S
|
1
|
| 1 |
IC50 = 205 nM
|
|
|
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CP0470730
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-pyridin-3-ylpyrrole-3-carboxamide
Show/Hide
|
C25H29Cl2N5O
|
1
|
| 1 |
IC50 = 209 nM
|
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CP0493630
|
2-Methyl-5-phenyl-1-propyl-N-(3-(4-(quinolin-8-yl)piperazin-1-yl)propyl)-1H-pyrrole-3-carboxamide
Show/Hide
|
C31H37N5O
|
1
|
| 1 |
IC50 = 210 nM
|
|
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CP0406098
|
N-[3-[4-(2,4-dichlorophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C26H30Cl2N4O
|
1
|
| 1 |
IC50 = 213 nM
|
|
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CP0902449
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
|
C28H36Cl2N4O
|
1
|
| 1 |
IC50 = 213 nM
|
|
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CP0857950
|
N-(4-Fluorophenyl)-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C19H26ClFN6
|
1
|
| 1 |
IC50 = 215 nM
|
|
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CP0871153
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-isobutyl-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H41Cl2N5O
|
1
|
| 1 |
IC50 = 216.8 nM
|
|
|
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CP0409810
|
N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2,5-dimethyl-1-(2-methylpropyl)imidazole-4-carboxamide
Show/Hide
|
C25H39N5O
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
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CP0416325
|
N-ethyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C23H27N3O2S
|
1
|
| 1 |
IC50 = 218 nM
|
|
|
|
CP0469927
|
N-(cyclopropylmethyl)-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C28H32F3N3O2S
|
1
|
| 1 |
IC50 = 221 nM
|
|
|
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CP0470721
|
N-[3-[4-(2-bromophenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C26H31BrN4O
|
1
|
| 1 |
IC50 = 221 nM
|
|
|
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CP0493628
|
N-[3-[4-(3-bromophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C28H35BrN4O
|
1
|
| 1 |
IC50 = 221 nM
|
|
|
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CP0469851
|
1-benzyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C34H40N4O
|
1
|
| 1 |
IC50 = 224 nM
|
|
|
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CP0847165
|
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1Himidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H39Cl2N5O4
|
1
|
| 1 |
IC50 = 231.5 nM
|
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|
|
CP0372470
|
5-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C26H29Cl3N4O
|
1
|
| 1 |
IC50 = 232 nM
|
|
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CP0470732
|
5-tert-Butyl-N-(2-(4-(3-chloro-2-methylphenyl)piperazin-1-yl)ethyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C24H35ClN4O
|
1
|
| 1 |
IC50 = 233 nM
|
|
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CP0851849
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H41Cl4N5O4
|
1
|
| 1 |
IC50 = 237 nM
|
|
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CP0917396
|
1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C31H43Cl2N5O3
|
1
|
| 1 |
IC50 = 241 nM
|
|
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CP0875067
|
N-((S)-3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H36Cl2FN5O2
|
1
|
| 1 |
IC50 = 244 nM
|
|
|
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CP0420502
|
N-[(2S)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(2-fluorophenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C27H34FN5O2
|
1
|
| 1 |
IC50 = 244 nM
|
|
|
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CP0429864
|
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C25H29ClN4O
|
1
|
| 1 |
IC50 = 245 nM
|
|
|
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CP0398560
|
N'-[(E)-[1-(4-iodophenyl)sulfonyl-4-nitroindol-3-yl]methylideneamino]-N,N-dimethylmethanimidamide
Show/Hide
|
C18H16IN5O4S
|
1
|
| 1 |
IC50 = 247 nM
|
|
|
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CP0847157
|
rac-N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride dihydrochloride
Show/Hide
|
C27H37Cl2N5O2
|
1
|
| 1 |
IC50 = 247.6 nM
|
|
|
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CP0574466
|
2-[4-[(4-fluorophenyl)methyl-[[4-(2-methylpropoxy)phenyl]methylcarbamoyl]amino]piperidin-1-yl]-N,N-dimethylacetamide
Show/Hide
|
C28H39FN4O3
|
1
|
| 1 |
IC50 = 252 nM
|
|
|
|
CP0871157
|
N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)propyl)-1-(2-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C30H43Cl2N5O2
|
1
|
| 1 |
IC50 = 253 nM
|
|
|
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CP0379360
|
N,N-dimethyl-N'-[(E)-[1-(4-methylphenyl)sulfonyl-4-nitroindol-3-yl]methylideneamino]methanimidamide
Show/Hide
|
C19H19N5O4S
|
1
|
| 1 |
IC50 = 253 nM
|
|
|
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CP0847159
|
N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C26H34Cl4FN5O2
|
1
|
| 1 |
IC50 = 254 nM
|
|
|
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CP0860115
|
2-cyclopropyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-6-methylpyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C24H34ClN5O
|
1
|
| 1 |
IC50 = 256 nM
|
|
|
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CP0918739
|
N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-5-methoxy-2,6-dimethylpyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C20H26Cl3N5O2
|
1
|
| 1 |
IC50 = 263 nM
|
|
|
|
CP0429728
|
US8835436, Example 141
Show/Hide
|
C26H30Cl3N5O2
|
1
|
| 1 |
IC50 = 264 nM
|
|
|
|
CP0918456
|
N-((R)-3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H36Cl2FN5O2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
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CP0385791
|
N-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-1-(2-fluorophenyl)-2,5-dimethylimidazole-4-carboxamide
Show/Hide
|
C27H34FN5O2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
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CP0851117
|
2-tert-butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-6-methylpyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C25H38ClN5O
|
1
|
| 1 |
IC50 = 274 nM
|
|
|
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CP0847163
|
1-(3-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl4N5O2
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1
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| 1 |
IC50 = 275.1 nM
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CP0401604
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N-methyl-N-(1-methylpiperidin-4-yl)-4-phenylbenzenesulfonamide
Show/Hide
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C19H24N2O2S
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1
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| 1 |
IC50 = 281 nM
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CP0373566
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N-(cyclopropylmethyl)-N-[3-(4-phenylpiperazin-1-yl)propyl]quinoline-8-sulfonamide
Show/Hide
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C26H32N4O2S
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1
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| 1 |
IC50 = 292 nM
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CP0847166
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1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-5-methyl-2-propyl-1Himidazole-4-carboxamide dihydrochloride
Show/Hide
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C31H43Cl2N5O4
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1
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| 1 |
IC50 = 294 nM
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CP0515345
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US8835436, Example 132
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C26H34N6O
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1
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| 1 |
IC50 = 297 nM
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CP0074514
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
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C25H28Cl2N4O
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1
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| 1 |
IC50 = 300 nM
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CP0406102
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
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C27H34N4O
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1
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| 1 |
IC50 = 300 nM
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CP0912349
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1-(2-Chlorophenyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl4N5O2
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1
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| 1 |
IC50 = 318 nM
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CP0039374
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
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C28H34Cl2N4O
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1
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| 1 |
IC50 = 324 nM
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CP0871031
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-fluorophenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C29H40Cl2FN5O2
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1
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| 1 |
IC50 = 327 nM
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CP0427524
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N-methyl-N-(1-methylpiperidin-4-yl)-4-propylbenzenesulfonamide
Show/Hide
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C16H26N2O2S
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1
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| 1 |
IC50 = 329 nM
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CP0382037
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N'-[(E)-[1-(benzenesulfonyl)-4-nitroindol-3-yl]methylideneamino]-N,N-dimethylmethanimidamide
Show/Hide
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C18H17N5O4S
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1
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| 1 |
IC50 = 329 nM
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CP0373829
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N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2-methyl-1-(2-methylpropyl)-5-phenylpyrrole-3-carboxamide
Show/Hide
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C29H37ClN4O
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1
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| 1 |
IC50 = 333 nM
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CP0844938
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5-(4-Chlorophenyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-1-propyl-1H-pyrrole-3-carboxamidehydrochloride
Show/Hide
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C28H34Cl4N4O
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1
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| 1 |
IC50 = 333 nM
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CP0857944
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6-(4-(4-fluorophenyl)piperazin-1-yl)-N-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C22H22FN7O
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1
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| 1 |
IC50 = 350 nM
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CP0419080
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4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide
Show/Hide
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C21H26F3N3O3S
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1
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| 1 |
IC50 = 352 nM
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CP0502357
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1,2-Dimethyl-5-phenyl-N-(3-(4-(quinolin-8-yl)piperazin-1-yl)propyl)-1H-pyrrole-3-carboxamide
Show/Hide
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C29H33N5O
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1
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| 1 |
IC50 = 352 nM
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CP0382795
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1-benzyl-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
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C32H34Cl2N4O
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1
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| 1 |
IC50 = 354 nM
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CP0893205
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-methoxyphenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
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C27H37Cl4N5O3
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1
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| 1 |
IC50 = 370 nM
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CP0400310
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-1-ethyl-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
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C27H32Cl2N4O
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1
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| 1 |
IC50 = 376 nM
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CP0406103
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5-tert-Butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-1,2-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
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C26H40N4O
|
1
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| 1 |
IC50 = 386 nM
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CP0487098
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N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propylnaphthalene-2-sulfonamide
Show/Hide
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C24H29N3O2S
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1
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| 1 |
IC50 = 389 nM
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CP0450054
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US8835436, Example 100
Show/Hide
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C28H37N5O3
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1
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| 1 |
IC50 = 389 nM
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CP0471449
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-2-methyl-1-(2-methylpropyl)-5-phenylpyrrole-3-carboxamide
Show/Hide
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C29H36Cl2N4O
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1
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| 1 |
IC50 = 406 nM
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CP0406101
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N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
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C27H32Cl2N4O
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1
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| 1 |
IC50 = 408 nM
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CP0916527
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2-Methyl-5-phenyl-1-propyl-N-(3-(4-(3-(trifluoromethyl)-phenyl)piperazin-1-yl)propyl)-1H-pyrrole-3-carboxamide hydrochloride
Show/Hide
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C29H36ClF3N4O
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1
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| 1 |
IC50 = 410 nM
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CP0379358
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N,N-dimethyl-N'-[(E)-(1-naphthalen-2-ylsulfonyl-4-nitroindol-3-yl)methylideneamino]methanimidamide
Show/Hide
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C22H19N5O4S
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1
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| 1 |
IC50 = 433 nM
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CP0382792
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N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-piperidin-1-ylpyrrole-3-carboxamide
Show/Hide
|
C30H38ClN5O
|
1
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| 1 |
IC50 = 441 nM
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CP0392991
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4-ethyl-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
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C15H24N2O2S
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1
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| 1 |
IC50 = 452 nM
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CP0645881
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6-tert-butyl-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methylpyrimidine-4-carboxamide Hydrochloride
Show/Hide
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C25H38ClN5O
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1
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| 1 |
IC50 = 458 nM
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CP0539551
|
US8835436, Example 109
Show/Hide
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C28H37N5O2
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1
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| 1 |
IC50 = 469 nM
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CP0414658
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N'-[(E)-[1-(2,5-dimethoxyphenyl)sulfonyl-4-nitroindol-3-yl]methylideneamino]-N,N-dimethylmethanimidamide
Show/Hide
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C20H21N5O6S
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1
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| 1 |
IC50 = 479 nM
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CP0431769
|
US8835436, Example 98
Show/Hide
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C23H34ClN5O2
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1
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| 1 |
IC50 = 480 nM
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CP0845010
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N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-6-isopropyl-2-methylpyrimidine-4-carboxamide Hydrochloride
Show/Hide
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C24H36ClN5O
|
1
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| 1 |
IC50 = 490 nM
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CP0427522
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N-methyl-N-(1-methylpiperidin-4-yl)naphthalene-1-sulfonamide
Show/Hide
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C17H22N2O2S
|
1
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| 1 |
IC50 = 502 nM
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CP0420463
|
US8835436, Example 121
Show/Hide
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C28H37N5O2
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1
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| 1 |
IC50 = 504 nM
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CP0932564
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N-tert-butyl-7-(3-(trifluoromethyl)phenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C16H20F3N3
|
1
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| 1 |
IC50 = 514 nM
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CP0503176
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4-tert-butyl-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
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C17H28N2O2S
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1
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| 1 |
IC50 = 519 nM
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CP0955625
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N-tert-butyl-7-(4-methoxyphenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
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C16H23N3O
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1
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| 1 |
IC50 = 534 nM
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CP0401642
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4-chloro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
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C13H19ClN2O2S
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1
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| 1 |
IC50 = 537 nM
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CP0379361
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N,N-dimethyl-N'-[(E)-(1-naphthalen-1-ylsulfonyl-4-nitroindol-3-yl)methylideneamino]methanimidamide
Show/Hide
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C22H19N5O4S
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1
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| 1 |
IC50 = 555 nM
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CP0371727
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N-(cyclopropylmethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]quinoline-8-sulfonamide
Show/Hide
|
C27H34N4O3S
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1
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| 1 |
IC50 = 561 nM
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CP0853011
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rac-N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(2-fluorophenyl)-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H36Cl2FN5O2
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1
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| 1 |
IC50 = 579 nM
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CP0851848
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N-(3-(4-(3-Chloro-2-methylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-(4-methoxyphenyl)-5-methyl-2-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C29H41Cl4N5O3
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1
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| 1 |
IC50 = 582 nM
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CP0847168
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(S)-N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1-phenyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C27H37Cl2N5O2
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1
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| 1 |
IC50 = 646 nM
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CP0472314
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N-[(2S)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-2,5-dimethyl-1-phenylimidazole-4-carboxamide
Show/Hide
|
C27H35N5O2
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1
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| 1 |
IC50 = 646 nM
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CP0497111
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-2-yl]naphthalene-2-sulfonamide
Show/Hide
|
C25H31N3O3S
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1
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| 1 |
IC50 = 664 nM
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CP0513542
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N-[3-[4-(2,3-dimethoxyphenyl)piperazin-1-yl]propyl]-1,2-dimethyl-5-phenylpyrrole-3-carboxamide
Show/Hide
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C28H36N4O3
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1
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| 1 |
IC50 = 666 nM
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CP0919957
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N-(4-Fluorophenyl)-7-methyl-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C20H28ClFN6
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1
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| 1 |
IC50 = 684 nM
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CP0919958
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6-(4-(4-fluorophenyl)piperazin-1-yl)-N-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C22H22FN7O
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1
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| 1 |
IC50 = 696 nM
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CP0480574
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N'-[(E)-[1-(4-fluorophenyl)sulfonyl-4-nitroindol-3-yl]methylideneamino]-N,N-dimethylmethanimidamide
Show/Hide
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C18H16FN5O4S
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1
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| 1 |
IC50 = 702 nM
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CP0463951
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N-(cyclopropylmethyl)-4-methoxy-N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]benzenesulfonamide
Show/Hide
|
C25H32F3N3O3S
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1
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| 1 |
IC50 = 726 nM
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CP0403039
|
US8835436, Example 106
Show/Hide
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C29H39N5O2
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1
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| 1 |
IC50 = 731 nM
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CP0913240
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N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-5-methoxy-2,6-dimethylpyrimidine-4-carboxamide hydrochloride
Show/Hide
|
C23H34ClN5O2
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1
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| 1 |
IC50 = 744 nM
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CP0552800
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N-(cyclopropylmethyl)-N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]benzamide
Show/Hide
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C24H29Cl2N3O
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1
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| 1 |
IC50 = 768.1 nM
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CP0447406
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N-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C31H42N4O
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1
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| 1 |
IC50 = 792 nM
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CP0401605
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4-methoxy-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C14H22N2O3S
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1
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| 1 |
IC50 = 831 nM
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CP0523815
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1,2-Dimethyl-N-(3-(4-(2-methylquinolin-8-yl)piperazin-1-yl)propyl)-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C30H35N5O
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1
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| 1 |
IC50 = 832 nM
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CP0853003
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-2,5-dimethyl-1-propyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C24H39Cl2N5O2
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1
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| 1 |
IC50 = 839.9 nM
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CP0474740
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-2,5-dimethyl-1-propylimidazole-4-carboxamide
Show/Hide
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C24H37N5O2
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1
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| 1 |
IC50 = 840 nM
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CP0845008
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N-(2-(4-(2,3-dimethylphenyl)piperazin-1-yl)ethyl)-5-methoxy-2,6-dimethylpyrimidine-4-carboxamide hydrochloride
Show/Hide
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C22H32ClN5O2
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1
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| 1 |
IC50 = 842 nM
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CP0473457
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N-[3-[4-(2,3-dimethoxyphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
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C30H40N4O3
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1
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| 1 |
IC50 = 874 nM
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CP0373836
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propyl]-2-methyl-1-(2-methylpropyl)-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C31H42N4O
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1
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| 1 |
IC50 = 897 nM
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CP0848760
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N4-(4-fluorophenyl)-N6-(4-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C19H17FN6
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1
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| 1 |
IC50 = 947 nM
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CP0513545
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-2-methyl-5-phenyl-1-propylpyrrole-3-carboxamide
Show/Hide
|
C29H38N4O2
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1
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| 1 |
IC50 = 953 nM
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CP0439977
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3-chloro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C13H19ClN2O2S
|
1
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| 1 |
IC50 = 986 nM
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CP0853004
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N-(3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-2-hydroxypropyl)-1-isobutyl-2,5-dimethyl-1H-imidazole-4-carboxamide dihydrochloride
Show/Hide
|
C25H41Cl2N5O2
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1
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| 1 |
IC50 = 1011 nM
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CP0538189
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N-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-2,5-dimethyl-1-(2-methylpropyl)imidazole-4-carboxamide
Show/Hide
|
C25H39N5O2
|
1
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| 1 |
IC50 = 1011 nM
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CP0399041
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N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C13H20N2O2S
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1
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| 1 |
IC50 = 1019 nM
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CP0382794
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N-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1-(cyclohexylmethyl)-2-methyl-5-phenylpyrrole-3-carboxamide
Show/Hide
|
C32H41ClN4O
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1
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| 1 |
IC50 = 1067 nM
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CP0429866
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1-(cyclohexylmethyl)-N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C34H46N4O
|
1
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| 1 |
IC50 = 1233 nM
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CP0508730
|
US8835436, Example 88
Show/Hide
|
C31H31BrCl3N5O
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1
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| 1 |
IC50 = 1262 nM
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CP0912131
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N6-benzyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C18H15FN6
|
1
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| 1 |
IC50 = 1268 nM
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CP0861747
|
4-(2-Benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl)thiomorpholine hydrochloride
Show/Hide
|
C19H25ClN4S
|
1
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| 1 |
IC50 = 1271 nM
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CP0856419
|
N-(4-fluorophenyl)-6-(4-(2-methoxyphenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C22H22FN7O
|
1
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| 1 |
IC50 = 1378 nM
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CP0377202
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N-methyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C22H25N3O2S
|
1
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| 1 |
IC50 = 1423 nM
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CP0955575
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7-(2-fluorophenyl)-N-neopentyl-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C16H22FN3
|
1
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| 1 |
IC50 = 1515 nM
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CP0427521
|
N,2-dimethyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C14H22N2O2S
|
1
|
| 1 |
IC50 = 1550 nM
|
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CP0420210
|
N'-[(E)-[1-(5-chloro-2-methoxyphenyl)sulfonyl-4-nitroindol-3-yl]methylideneamino]-N,N-dimethylmethanimidamide
Show/Hide
|
C19H18ClN5O5S
|
1
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| 1 |
IC50 = 1593 nM
|
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CP0377208
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N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C21H23N3O2S
|
1
|
| 1 |
IC50 = 1616 nM
|
|
|
|
CP0467639
|
N-methyl-N-(1-methylpiperidin-4-yl)-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C14H19F3N2O2S
|
1
|
| 1 |
IC50 = 1683 nM
|
|
|
|
CP0459682
|
4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-piperazin-1-yl]-1-methyl-propyl}-benzenesulfonamide
Show/Hide
|
C22H28F3N3O3S
|
1
|
| 1 |
IC50 = 1824 nM
|
|
|
|
CP0504041
|
3-fluoro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C13H19FN2O2S
|
1
|
| 1 |
IC50 = 1859 nM
|
|
|
|
CP0857942
|
N4-(4-chlorophenyl)-N6,N6-diethyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C15H17ClN6
|
1
|
| 1 |
IC50 = 1894 nM
|
|
|
|
CP0424880
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N-propan-2-ylbenzamide
Show/Hide
|
C23H29Cl2N3O
|
1
|
| 1 |
IC50 = 2008 nM
|
|
|
|
CP0860610
|
N6,N6-diethyl-N4-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C16H20N6O
|
1
|
| 1 |
IC50 = 2084 nM
|
|
|
|
CP0439975
|
N,4-dimethyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C14H22N2O2S
|
1
|
| 1 |
IC50 = 2130 nM
|
|
|
|
CP0424883
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N-(oxetan-3-yl)benzamide
Show/Hide
|
C23H27Cl2N3O2
|
1
|
| 1 |
IC50 = 2177 nM
|
|
|
|
CP0864840
|
N-(4-fluorophenyl)-6-(piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C16H17FN6
|
1
|
| 1 |
IC50 = 2198 nM
|
|
|
|
CP0415115
|
N-(cyclopropylmethyl)-4-methoxy-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]benzenesulfonamide
Show/Hide
|
C25H35N3O4S
|
1
|
| 1 |
IC50 = 2210 nM
|
|
|
|
CP0411036
|
US8835436, Example 89
Show/Hide
|
C31H30BrCl4N5O
|
1
|
| 1 |
IC50 = 2320 nM
|
|
|
|
CP0439973
|
N-methyl-N-(1-methylpiperidin-4-yl)-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C14H19F3N2O3S
|
1
|
| 1 |
IC50 = 2448 nM
|
|
|
|
CP0876517
|
N-(4-fluorophenyl)-6-morpholino-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C15H15FN6O
|
1
|
| 1 |
IC50 = 2618 nM
|
|
|
|
CP0857943
|
4-(furan-2-ylmethoxy)-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine hydrochloride
Show/Hide
|
C18H26ClN5O2
|
1
|
| 1 |
IC50 = 2625 nM
|
|
|
|
CP0848758
|
N4-(3,4-dimethylphenyl)-N6,N6-diethyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C17H22N6
|
1
|
| 1 |
IC50 = 2753 nM
|
|
|
|
CP0943580
|
4-(7-(tert-butylamino)-3,4-dihydro-2H-1,4-diazepin-5-yl)benzonitrile
Show/Hide
|
C16H20N4
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0454934
|
2-chloro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C13H19ClN2O2S
|
1
|
| 1 |
IC50 = 3180 nM
|
|
|
|
CP0532001
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N-propylbenzamide
Show/Hide
|
C23H29Cl2N3O
|
1
|
| 1 |
IC50 = 3249 nM
|
|
|
|
CP0399040
|
N,3-dimethyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C14H22N2O2S
|
1
|
| 1 |
IC50 = 3450 nM
|
|
|
|
CP0848759
|
N6-cyclohexyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C17H19FN6
|
1
|
| 1 |
IC50 = 3666 nM
|
|
|
|
CP0856418
|
N-(4-fluorophenyl)-6-(4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C17H19FN6
|
1
|
| 1 |
IC50 = 3673 nM
|
|
|
|
CP0873149
|
1-(2-Methoxyphenyl)-4-{2-[2-(2,3,5-trimethylphenoxy)ethoxy]ethyl}piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O3
|
1
|
| 1 |
IC50 = 4011 nM
|
|
|
|
CP0496121
|
1-(cyclohexylmethyl)-N-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C32H40Cl2N4O
|
1
|
| 1 |
IC50 = 4383 nM
|
|
|
|
CP0848761
|
N6-cyclopentyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C16H17FN6
|
1
|
| 1 |
IC50 = 4499 nM
|
|
|
|
CP0856417
|
N6,N6-diethyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C15H17FN6
|
1
|
| 1 |
IC50 = 4535 nM
|
|
|
|
CP0861030
|
1,2-Dimethyl-5-phenyl-N-(3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)-1H-pyrrole-3-carboxamide dihydrochloride
Show/Hide
|
C25H33Cl2N5O
|
1
|
| 1 |
IC50 = 4559 nM
|
|
|
|
CP0848757
|
N6,N6-diethyl-N4-o-tolyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C16H20N6
|
1
|
| 1 |
IC50 = 4578 nM
|
|
|
|
CP0857941
|
N4-(4-fluorophenyl)-N6,N6-dimethyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C13H13FN6
|
1
|
| 1 |
IC50 = 4880 nM
|
|
|
|
CP0233824
|
4-Methoxy-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide
Show/Hide
|
C21H29N3O4S
|
1
|
| 1 |
IC50 = 5168 nM
|
|
|
|
CP0876523
|
N4-(4-fluorophenyl)-N6-(3-methoxypropyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C15H17FN6O
|
1
|
| 1 |
IC50 = 5283 nM
|
|
|
|
CP0864805
|
6-(3,5-dimethylpiperidin-1-yl)-N-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
|
C18H21FN6
|
1
|
| 1 |
IC50 = 5866 nM
|
|
|
|
CP0401603
|
4-fluoro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C13H19FN2O2S
|
1
|
| 1 |
IC50 = 5900 nM
|
|
|
|
CP0496232
|
N,3,4-trimethyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C15H24N2O2S
|
1
|
| 1 |
IC50 = 5980 nM
|
|
|
|
CP0846050
|
N6-allyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C14H13FN6
|
1
|
| 1 |
IC50 = 6577 nM
|
|
|
|
CP0853339
|
1-{2-[2-(2,3-Dimethylphenoxy)ethoxy]ethyl}-4-phenethylpiperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O2
|
1
|
| 1 |
IC50 = 6970 nM
|
|
|
|
CP0483491
|
N-propyl-N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]benzamide
Show/Hide
|
C22H30N4O
|
1
|
| 1 |
IC50 = 7549 nM
|
|
|
|
CP0528554
|
N-(cyclopropylmethyl)-N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]benzamide
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
IC50 = 7719 nM
|
|
|
|
CP0857446
|
N4-(4-fluorophenyl)-N6-(2-morpholinoethyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C17H20FN7O
|
1
|
| 1 |
IC50 = 9741 nM
|
|
|
|
CP0427520
|
N-methyl-N-(1-methylpiperidin-4-yl)-4-nitrobenzenesulfonamide
Show/Hide
|
C13H19N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0439974
|
4-cyano-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C14H19N3O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0452120
|
2-fluoro-N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide
Show/Hide
|
C13H19FN2O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0496233
|
N-methyl-N-(1-methylpiperidin-4-yl)-1-benzothiophene-7-sulfonamide
Show/Hide
|
C15H20N2O2S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0848762
|
N6-ethyl-N4-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C13H13FN6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0856415
|
N-(3-Methoxyphenyl)-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C20H29ClN6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0856416
|
N,N-Dimethyl-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C15H27ClN6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0857445
|
N4-(4-fluorophenyl)-N6-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C12H11FN6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0857447
|
3-(4-(4-fluorophenylamino)-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)propan-1-ol
Show/Hide
|
C14H15FN6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0857936
|
2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine hydrochloride
Show/Hide
|
C13H22ClN5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0857940
|
2-(4-Methylpiperazin-1-yl)-N-ethyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C15H27ClN6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0857949
|
4-(2-(4-Methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl)thiomorpholine hydrochloride
Show/Hide
|
C17H29ClN6S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0864804
|
N-Methyl-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C14H25ClN6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0864839
|
N6-ethyl-N4-phenyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C13H14N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0876524
|
N4-(4-fluorophenyl)-N6-(2-methoxyethyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C14H15FN6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0912127
|
N4-phenyl-N6-propyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Show/Hide
|
C14H16N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0919956
|
N,N-Diethyl-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine hydrochloride
Show/Hide
|
C17H31ClN6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0946361
|
4-Methoxy-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine hydrochloride
Show/Hide
|
C14H24ClN5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0946362
|
4-(2-(4-Methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl)morpholine hydrochloride
Show/Hide
|
C17H29ClN6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0864251
|
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O3
|
1
|
| 1 |
IC50 = 18200 nM
|
|
|
|
CP0873148
|
1-[3-(4-Chloro-3-methylphenoxy)propyl]-4-phenylpiperazine dihydrochloride
Show/Hide
|
C20H27Cl3N2O
|
1
|
| 1 |
IC50 = 85800 nM
|
|
|
|
CP0548126
|
1-(1-benzothiophen-4-ylmethyl)-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
|
C27H35N3O2S
|
1
|
| 1 |
IC50 > 500 nM
|
|
|
|
CP0550410
|
1-(1H-benzimidazol-4-ylmethyl)-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
|
C26H35N5O2
|
1
|
| 1 |
IC50 > 500 nM
|
|
|
|
CP0571638
|
1-[(6-fluoropyridin-3-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
|
C24H33FN4O2
|
1
|
| 1 |
IC50 > 500 nM
|
|
|
|
CP0577081
|
1-[3-(dimethylamino)cyclohexyl]-1-[(4-fluorophenyl)methyl]-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
|
C27H38FN3O2
|
1
|
| 1 |
IC50 > 500 nM
|
|
|
|
CP0578314
|
1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Show/Hide
|
C24H36N4O3
|
1
|
| 1 |
IC50 > 500 nM
|
|
|
|
CP0578316
|
1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]-1-(1H-pyrazol-4-ylmethyl)urea
Show/Hide
|
C22H33N5O2
|
1
|
| 1 |
IC50 > 500 nM
|
|
|
|
CP0911104
|
N,N-diethyl-7-(2-fluorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C15H20FN3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0911105
|
5-(piperazin-1-yl)-7-p-tolyl-2,3-dihydro-1H-1,4-diazepine
Show/Hide
|
C16H22N4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0932722
|
5-morpholino-7-p-tolyl-2,3-dihydro-1H-1,4-diazepine
Show/Hide
|
C16H21N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0949503
|
N,N-diethyl-7-p-tolyl-2,3-dihydro-1H-1,4-diazepin-5-amine
Show/Hide
|
C16H23N3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0528055
|
6-fluoro-3-[3-[3-(naphthalen-2-ylsulfonylmethyl)pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
|
C25H25FN2O3S
|
1
|
| 1 |
Ki = 0.2455 nM
|
|
|
|
CP0395869
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
|
C22H28N4O2S2
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0039958
|
(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H27FN4O2
|
2
|
| 1 |
Ki = 0.5 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0307921
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0399032
|
6-chloro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
|
C26H27ClFN3O3S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0447214
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]naphthalene-1-sulfonamide
Show/Hide
|
C26H28FN3O3S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0534014
|
6-fluoro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23F2N3O3S2
|
1
|
| 1 |
Ki = 0.6457 nM
|
|
|
|
CP0549990
|
N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H24FN3O3S2
|
1
|
| 1 |
Ki = 0.6918 nM
|
|
|
|
CP0440756
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
|
C25H28N4O3S
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0443093
|
5-fluoro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C25H27F2N3O3S2
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0443103
|
N-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]naphthalene-1-sulfonamide
Show/Hide
|
C24H24FN3O3S
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0447245
|
6-chloro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
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C24H25ClFN3O3S2
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1
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| 1 |
Ki = 0.8 nM
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CP0461312
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-1-benzothiophene-2-sulfonamide
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C23H24FN3O3S2
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1
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| 1 |
Ki = 0.9 nM
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CP0486986
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N-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]naphthalene-2-sulfonamide
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C23H24N4O2S2
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1
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| 1 |
Ki = 0.9 nM
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CP0430935
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8-[5-(2-methoxy-5-phenylphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
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C25H29N3O4
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1
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| 1 |
Ki = 1 nM
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CP0150364
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2,8-Dimethyl-5-((Z)-styryl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
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C21H22N2
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1
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| 1 |
Ki = 1 nM
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CP0440753
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5-chloro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-3-methyl-1-benzothiophene-2-sulfonamide
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C25H27ClFN3O3S2
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1
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| 1 |
Ki = 1 nM
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CP0353494
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2,8-Dimethyl-5-(2-p-tolylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
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C22H26N2
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1
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| 1 |
Ki = 1.096 nM
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CP0026495
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CHEBI:51137
Show/Hide
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C18H20N2
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3
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| 1 |
Ki = 1.2 nM
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| 2 |
Ki = 2 nM
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| 3 |
Ki = 2.2 nM
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CP0468503
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N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-3-methylbenzenesulfonamide
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C21H26N4O2S2
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1
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| 1 |
Ki = 1.3 nM
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CP0440757
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3-chloro-4-fluoro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]benzenesulfonamide
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C21H22ClF2N3O3S
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1
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| 1 |
Ki = 1.5 nM
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CP0461293
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N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
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C25H28N4O2S2
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1
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| 1 |
Ki = 1.5 nM
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CP0552785
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N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]naphthalene-2-sulfonamide
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C25H26FN3O3S
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1
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| 1 |
Ki = 1.514 nM
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CP0040671
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8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
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C23H26FN3O2
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1
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| 1 |
Ki = 1.585 nM
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CP0037301
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CHEBI:584020
Show/Hide
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C21H27N3O2
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1
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| 1 |
Ki = 1.585 nM
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CP0489949
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-1-benzothiophene-3-sulfonamide
Show/Hide
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C23H24FN3O3S2
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1
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| 1 |
Ki = 1.6 nM
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CP0532876
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3-[3-[3-[(3,4-dichlorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole
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C21H21Cl2FN2O3S
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1
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| 1 |
Ki = 1.698 nM
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CP0551501
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3-[3-[3-[(3,4-dimethylphenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole
Show/Hide
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C23H27FN2O3S
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1
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| 1 |
Ki = 1.698 nM
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CP0440755
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N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
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C26H28FN3O3S
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1
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| 1 |
Ki = 1.7 nM
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CP0486995
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]naphthalene-1-sulfonamide
Show/Hide
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C25H26FN3O3S
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1
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| 1 |
Ki = 1.7 nM
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CP0056386
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5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one
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C21H21ClN4OS
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1
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| 1 |
Ki = 1.7 nM
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CP0857136
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6-acetyl-4,7-dimethyl-5-{4-[4-(4-chlorophenyl)piperazin-1-yl]butoxy}coumarin
Show/Hide
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C27H31ClN2O4
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1
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| 1 |
Ki = 1.7 nM
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CP0510211
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N-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]naphthalene-2-sulfonamide
Show/Hide
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C24H24FN3O3S
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1
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| 1 |
Ki = 1.8 nM
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CP0045063
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2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
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C17H20N4S
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3
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| 1 |
Ki = 1.905 nM
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| 2 |
Ki = 4 nM
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| 3 |
Ki = 5.6 nM
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CP0528049
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6-fluoro-3-[3-[3-[[4-(trifluoromethyl)phenyl]sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole
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C22H22F4N2O3S
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1
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| 1 |
Ki = 1.95 nM
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CP0237538
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2,8-Dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
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C21H24N2
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1
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| 1 |
Ki = 1.995 nM
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CP0037955
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METHIOTHEPIN
Show/Hide
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C20H24N2S2
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1
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| 1 |
Ki = 1.995 nM
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CP0395874
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N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
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C23H28FN3O3S
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1
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| 1 |
Ki = 2.1 nM
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CP0395881
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3,4-dichloro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]benzenesulfonamide
Show/Hide
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C21H22Cl2FN3O3S
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1
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| 1 |
Ki = 2.2 nM
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CP0447121
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N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-4-(trifluoromethoxy)benzenesulfonamide
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C22H25F3N4O3S2
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1
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| 1 |
Ki = 2.2 nM
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CP0461307
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5-fluoro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
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C24H25F2N3O3S2
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1
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| 1 |
Ki = 2.3 nM
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CP0473172
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6-chloro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H23ClFN3O3S2
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1
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| 1 |
Ki = 2.6 nM
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CP0488670
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N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzofuran-2-sulfonamide
Show/Hide
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C23H24FN3O4S
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1
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| 1 |
Ki = 2.754 nM
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CP0395875
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C25H26FN3O3S
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1
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| 1 |
Ki = 2.8 nM
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CP0532871
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6-fluoro-3-[3-[3-[[3-(trifluoromethyl)phenyl]sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
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C22H22F4N2O3S
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1
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| 1 |
Ki = 2.951 nM
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CP0468502
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6-chloro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C25H25ClFN3O3S
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1
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| 1 |
Ki = 3.1 nM
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CP0440062
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N-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
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C21H24FN3O3S
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1
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| 1 |
Ki = 3.5 nM
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CP0528053
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3-chloro-4-fluoro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]benzenesulfonamide
Show/Hide
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C21H22ClF2N3O3S
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1
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| 1 |
Ki = 3.548 nM
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CP0481184
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N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
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C23H25F4N3O4S
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1
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| 1 |
Ki = 3.6 nM
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CP0447122
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
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C22H26FN3O3S
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1
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| 1 |
Ki = 3.7 nM
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CP0468501
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
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C22H23F4N3O4S
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1
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| 1 |
Ki = 3.8 nM
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CP0552784
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3-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]benzenesulfonamide
Show/Hide
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C21H23ClFN3O3S
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1
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| 1 |
Ki = 3.89 nM
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CP0905189
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6-acetyl-4,7-dimethyl-5-{3-[4-(4-chlorophenyl)piperazin-1-yl]propoxy}coumarin
Show/Hide
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C26H29ClN2O4
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1
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| 1 |
Ki = 4 nM
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CP0525896
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N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzamide
Show/Hide
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C24H30N4OS
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1
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| 1 |
Ki = 4 nM
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CP0530031
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(1R,2S,6R,7S)-4-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
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C26H34N4O2S
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1
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| 1 |
Ki = 4 nM
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CP0488671
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6-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H23ClFN3O3S2
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1
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| 1 |
Ki = 4.169 nM
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CP0528228
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N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-1-benzothiophene-3-sulfonamide
Show/Hide
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C23H24FN3O3S2
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1
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| 1 |
Ki = 4.169 nM
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CP0488674
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3-[3-[3-[(3-chlorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole
Show/Hide
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C21H22ClFN2O3S
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1
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| 1 |
Ki = 4.365 nM
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CP0499522
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3,4-dichloro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]benzenesulfonamide
Show/Hide
|
C22H24Cl2FN3O3S
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1
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| 1 |
Ki = 4.9 nM
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CP0389125
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6-fluoro-3-[1-[2-[(2R)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperidin-4-yl]-1,2-benzoxazole
Show/Hide
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C27H29FN4O3S
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1
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| 1 |
Ki = 5 nM
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CP0491001
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2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C23H28N6OS
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1
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| 1 |
Ki = 5 nM
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CP0443102
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]thiophene-2-sulfonamide
Show/Hide
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C19H22FN3O3S2
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1
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| 1 |
Ki = 5.1 nM
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CP0395870
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N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]thiophene-2-sulfonamide
Show/Hide
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C19H24N4O2S3
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1
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| 1 |
Ki = 5.5 nM
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CP0447218
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N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-3-sulfonamide
Show/Hide
|
C24H26FN3O3S2
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1
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| 1 |
Ki = 5.7 nM
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CP0546332
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6-fluoro-3-[3-[3-[(3-methylphenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
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C22H25FN2O3S
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1
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| 1 |
Ki = 5.888 nM
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CP0466976
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N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H26N4O2S3
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1
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| 1 |
Ki = 6 nM
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CP0445939
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8-acetyl-7-[3-[4-(3-bromophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H27BrN2O4
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1
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| 1 |
Ki = 6 nM
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CP0396617
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6-fluoro-3-[1-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperidin-4-yl]-1,2-benzoxazole
Show/Hide
|
C27H29FN4O3S
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1
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| 1 |
Ki = 6 nM
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CP0473056
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3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1,3-benzoxazol-2-one
Show/Hide
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C24H28N4O2S
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1
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| 1 |
Ki = 6 nM
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CP0484413
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3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1H-benzimidazol-2-one
Show/Hide
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C24H29N5OS
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1
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| 1 |
Ki = 6 nM
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CP0492700
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8-[5-(4,5-dichloro-2-methoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C19H23Cl2N3O4
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1
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| 1 |
Ki = 6.31 nM
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CP0551500
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3-[3-[3-[(3-chloro-4-fluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole
Show/Hide
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C21H21ClF2N2O3S
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1
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| 1 |
Ki = 6.31 nM
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CP0447097
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]imidazo[1,2-a]pyridine-3-sulfonamide
Show/Hide
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C22H24FN5O3S
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1
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| 1 |
Ki = 6.5 nM
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CP0447124
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N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-6-chloro-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H25ClN4O2S3
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1
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| 1 |
Ki = 6.5 nM
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CP0468506
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N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-5-fluoro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H27FN4O2S3
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1
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| 1 |
Ki = 6.5 nM
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CP0466083
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8-acetyl-7-[4-[4-(3-bromophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H29BrN2O4
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1
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| 1 |
Ki = 6.5 nM
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CP0528047
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5-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
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C24H25ClFN3O3S2
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1
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| 1 |
Ki = 6.918 nM
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CP0416077
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8-acetyl-7-[3-[4-(2-bromophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H27BrN2O4
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1
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| 1 |
Ki = 7 nM
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CP0396074
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5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azetidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H28N4O2S2
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1
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| 1 |
Ki = 7 nM
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CP0440922
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N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-5-fluoro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
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C24H27FN4O3S2
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1
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| 1 |
Ki = 7.4 nM
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CP0395876
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N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
|
C22H25N5O2S3
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1
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| 1 |
Ki = 7.5 nM
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CP0395872
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N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-6-chloronaphthalene-2-sulfonamide
Show/Hide
|
C25H27ClN4O3S
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1
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| 1 |
Ki = 7.7 nM
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CP0520931
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8-acetyl-7-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H26Cl2N2O4
|
1
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| 1 |
Ki = 8 nM
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CP0541206
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8-acetyl-7-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C26H30N2O5
|
1
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| 1 |
Ki = 8 nM
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CP0447107
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N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-6-chloronaphthalene-2-sulfonamide
Show/Hide
|
C25H27ClN4O2S2
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1
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| 1 |
Ki = 8.1 nM
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CP0481185
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-3-sulfonamide
Show/Hide
|
C22H26N6O2S2
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1
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| 1 |
Ki = 8.1 nM
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CP0482709
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
|
C21H23N5O2S3
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1
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| 1 |
Ki = 8.4 nM
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|
|
|
CP0443106
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
|
C23H25FN4O3S2
|
1
|
| 1 |
Ki = 8.5 nM
|
|
|
|
CP0458499
|
N-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
|
C20H24N4O2S2
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
|
CP0447213
|
3-chloro-4-fluoro-N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]benzenesulfonamide
Show/Hide
|
C22H24ClF2N3O3S
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0086335
|
4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0416050
|
5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0869883
|
6-acetyl-4,7-dimethyl-5-{4-[4-(2-fluorophenyl)piperazin-1-yl]butoxy}coumarin
Show/Hide
|
C27H31FN2O4
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0443105
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
|
C22H23FN4O3S2
|
1
|
| 1 |
Ki = 9.1 nM
|
|
|
|
CP0506649
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]thiophene-2-sulfonamide
Show/Hide
|
C18H22N4O2S3
|
1
|
| 1 |
Ki = 9.1 nM
|
|
|
|
CP0447217
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]thiophene-2-sulfonamide
Show/Hide
|
C20H24FN3O3S2
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0468504
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C21H23F3N4O3S2
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0482708
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-6-chloro-1-benzothiophene-2-sulfonamide
Show/Hide
|
C22H23ClN4O2S3
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0489950
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]imidazo[1,2-a]pyridine-3-sulfonamide
Show/Hide
|
C23H26FN5O3S
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0456368
|
8-acetyl-7-[3-[4-(4-chlorophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H27ClN2O4
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0895862
|
1-Isopropyl-N-[[1-[2-(4-hydroxyphenyl)ethyl]-4-piperidinyl]-methyl]-1H-indazole-3-carboxamide hydrochloride
Show/Hide
|
C25H33ClN4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0440055
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-3,4-dichlorobenzenesulfonamide
Show/Hide
|
C21H24Cl2N4O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0461294
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C24H26N4O2S2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0519825
|
8-acetyl-7-[4-[4-(2-bromophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H29BrN2O4
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0445918
|
3-[4-[2-[(2R)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0395873
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-6-chloro-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H25ClN4O3S2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0461314
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C22H24N4O2S3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0447123
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3,4-dichlorobenzenesulfonamide
Show/Hide
|
C21H24Cl2N4O2S2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0461305
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]imidazo[1,2-a]pyridine-3-sulfonamide
Show/Hide
|
C21H24N6O2S2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0390939
|
6-fluoro-3-[1-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperidin-4-yl]-1,2-benzoxazole
Show/Hide
|
C27H29FN4O3S
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0414533
|
3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C27H33N5OS
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0033479
|
(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Show/Hide
|
C17H19ClN2S
|
1
|
| 1 |
Ki = 12.02 nM
|
|
|
|
CP0466084
|
8-acetyl-7-[3-[4-(3,5-dimethylphenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C27H32N2O4
|
1
|
| 1 |
Ki = 12.5 nM
|
|
|
|
CP0437463
|
8-[5-(5-chloro-2-methoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
|
C19H24ClN3O4
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0534012
|
6-chloro-N-[(3S,5S)-1-[3-(6-fluoro-1,2-benzoxazol-3-yl)propyl]-5-methylpyrrolidin-3-yl]naphthalene-2-sulfonamide
Show/Hide
|
C25H25ClFN3O3S
|
1
|
| 1 |
Ki = 12.88 nM
|
|
|
|
CP0573889
|
3-[3-[3-[(3,4-difluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-6-fluoro-1,2-benzoxazole
Show/Hide
|
C21H21F3N2O3S
|
1
|
| 1 |
Ki = 12.88 nM
|
|
|
|
CP0447262
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-3-sulfonamide
Show/Hide
|
C22H26N6O3S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0468505
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-6-chloronaphthalene-2-sulfonamide
Show/Hide
|
C24H25ClN4O2S2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
2
|
| 1 |
Ki = 13 nM
|
|
|
| 2 |
Ki = 33 nM
|
|
|
|
CP0219574
|
3-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0538566
|
2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexylsulfanyl]-1,3-benzoxazole
Show/Hide
|
C24H28N4OS2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0542762
|
2-N-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C19H28Cl2N8
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0488673
|
6-fluoro-3-[3-[3-[(4-fluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
|
C21H22F2N2O3S
|
1
|
| 1 |
Ki = 13.49 nM
|
|
|
|
CP0395871
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-5-fluoro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H25FN4O2S3
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0506619
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-3-chloro-4-fluorobenzenesulfonamide
Show/Hide
|
C20H22ClFN4O2S2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0510212
|
N-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3-chloro-4-fluorobenzenesulfonamide
Show/Hide
|
C21H24ClFN4O2S2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0396077
|
3-[4-[2-[(2R)-1-isoquinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0414548
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzenesulfonamide
Show/Hide
|
C23H30N4O2S2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0416051
|
3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0466254
|
4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azetidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H28N4O2S2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0447211
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-3-chloro-4-fluorobenzenesulfonamide
Show/Hide
|
C21H24ClFN4O3S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0571683
|
2-N-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C18H26Cl2N8
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0487359
|
3-[4-[2-[(2S)-1-isoquinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0450842
|
5-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0031743
|
1H-imidazo[4,5-c]pyridine derivative
Show/Hide
|
C18H26N4O2S
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0375150
|
8-[5-(2,5-dimethoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
|
C20H27N3O5
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0490833
|
8-acetyl-7-[4-[4-(2-chlorophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H29ClN2O4
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0490835
|
8-acetyl-4-methyl-7-[3-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]propoxy]chromen-2-one
Show/Hide
|
C26H27F3N2O4
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0526779
|
6-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H32N4O2S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0450839
|
3-[4-[2-[(2R)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0490834
|
8-acetyl-7-[3-[4-(2-chlorophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H27ClN2O4
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0008601
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
Show/Hide
|
C21H23ClFNO2
|
2
|
| 1 |
Ki = 22.91 nM
|
|
|
| 2 |
Ki = 89 nM
|
|
|
|
CP0429637
|
2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C24H28N4O3S2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0390938
|
3-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylazetidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C25H27N5O2S2
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0348615
|
2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-hexyl]-isoindole-1,3-dione
Show/Hide
|
C25H28N4O2S
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0542766
|
2-N-[2-(1H-indol-3-yl)ethyl]-4-N-[4-(4-phenylpiperazin-1-yl)butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C27H35N9
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0562769
|
2-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C17H24Cl2N8
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0483771
|
N-[3-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]propyl]-3,4-dichlorobenzenesulfonamide
Show/Hide
|
C20H22Cl2N4O2S2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0473171
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
|
C22H28N4O3S
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0073333
|
3-benzenesulfonyl-8-piperazin-1-ylquinoline
Show/Hide
|
C19H19N3O2S
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0390937
|
3-[4-[2-[(2S)-1-quinolin-4-ylsulfonylazepan-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C28H33N5O2S2
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0415732
|
4-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0532783
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-4-methyl-N-phenylbenzenesulfonamide
Show/Hide
|
C30H36N4O2S2
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0387316
|
8-acetyl-7-[3-[4-(2-fluorophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H27FN2O4
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0852532
|
6-acetyl-4,7-dimethyl-5-{3-[4-(2-fluorophenyl)piperazin-1-yl]propoxy}coumarin
Show/Hide
|
C26H29FN2O4
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0042927
|
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C23H27Cl2N3O2
|
2
|
| 1 |
Ki = 28 nM
|
|
|
| 2 |
Ki = 63 nM
|
|
|
|
CP0396615
|
3-[4-[2-[(2R)-1-quinolin-5-ylsulfonylpiperidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C27H31N5O2S2
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0408251
|
4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azepan-1-yl]sulfonylisoquinoline
Show/Hide
|
C29H34N4O2S2
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0386707
|
8-acetyl-7-[3-[4-(3-methoxyphenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C26H30N2O5
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0386710
|
8-acetyl-7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H28Cl2N2O4
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0415694
|
3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylazetidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C25H27N5O2S2
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0476720
|
3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylazepan-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C28H33N5O2S2
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0336202
|
[4-[2-[4-[(2-methylpyrrolo[3,4-c]quinolin-4-yl)oxymethyl]piperidin-1-yl]ethyl]phenyl]methanol
Show/Hide
|
C27H31N3O2
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0746540
|
1-Isopropyl-N-[[1-(2-phenylethyl)-4-piperidinyl]methyl]-1H-indazole-3-carboxamide hydrochloride
Show/Hide
|
C25H33ClN4O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0526780
|
3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0391297
|
3-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzoxazole
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0445915
|
5-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C28H32N4O2S2
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0487358
|
3-[4-[2-[(2R)-1-quinolin-4-ylsulfonylpiperidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C27H31N5O2S2
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0396076
|
5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0552783
|
6-fluoro-3-[3-[3-[(3-fluorophenyl)sulfonylmethyl]pyrrolidin-1-yl]propyl]-1,2-benzoxazole
Show/Hide
|
C21H22F2N2O3S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0529086
|
3-[4-[2-[(2S)-1-isoquinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzoxazole
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0386713
|
8-acetyl-4-methyl-7-[3-[4-(4-nitrophenyl)piperazin-1-yl]propoxy]chromen-2-one
Show/Hide
|
C25H27N3O6
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0864710
|
5-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C24H26Cl2N2O3
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0417064
|
1-[6-(4-pyrimidin-2-ylpiperazin-1-yl)hexyl]benzo[cd]indol-2-one
Show/Hide
|
C25H29N5O
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0526778
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H32N4O2S2
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0911152
|
6-acetyl-4,7-dimethyl-5-(4-(4-(4-nitrophenyl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
|
C27H31N3O6
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0416080
|
8-acetyl-7-[4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C28H34N2O4
|
1
|
| 1 |
Ki = 46.8 nM
|
|
|
|
CP0489015
|
8-acetyl-7-[4-[4-(2-fluorophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H29FN2O4
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0568318
|
2-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C22H27Cl2N5O
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0864708
|
6-acetyl-4,7-dimethyl-5-{3-[4-(3-methoxyphenyl)-piperazin-1-yl]propoxy}coumarin
Show/Hide
|
C27H32N2O5
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0560081
|
8-acetyl-4-methyl-7-[4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]butoxy]chromen-2-one
Show/Hide
|
C27H29F3N2O4
|
1
|
| 1 |
Ki = 48.7 nM
|
|
|
|
CP0391298
|
3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzoxazole
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0390936
|
5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azepan-1-yl]sulfonylquinoline
Show/Hide
|
C29H34N4O2S2
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0532785
|
2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C29H30N4O2S
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0906607
|
4,7-dimethyl-5-{3-[4-(2-fluorophenyl)piperazin-1-yl]propoxy}coumarin
Show/Hide
|
C24H27FN2O3
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0414547
|
1-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
|
C28H30N4OS
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0488917
|
8-acetyl-7-[4-[4-(4-chlorophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H29ClN2O4
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0457174
|
8-acetyl-7-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C27H32N2O5
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0396080
|
5-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0450872
|
8-acetyl-7-[4-[4-(3,5-dimethylphenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C28H34N2O4
|
1
|
| 1 |
Ki = 58 nM
|
|
|
|
CP0485157
|
1'-[2-[4-(4-fluorophenyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C23H27FN4O
|
1
|
| 1 |
Ki = 59 nM
|
|
|
|
CP0017601
|
2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole
Show/Hide
|
C21H25N3
|
1
|
| 1 |
Ki = 61.66 nM
|
|
|
|
CP0486993
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-6-chloro-1-benzothiophene-2-sulfonamide
Show/Hide
|
C22H23ClN4O3S2
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0478914
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]naphthalene-1-sulfonamide
Show/Hide
|
C27H32N4O2S2
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0472430
|
4-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C28H32N4O2S2
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0857130
|
6-acetyl-4,7-dimethyl-5-{3-[4-(2-cyanophenyl)piperazin-1-yl]-propoxy}coumarin
Show/Hide
|
C27H29N3O4
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0527898
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
Show/Hide
|
C30H33F3N4O2S2
|
1
|
| 1 |
Ki = 65 nM
|
|
|
|
CP0891134
|
6-acetyl-4,7-dimethyl-5-{3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy}coumarin
Show/Hide
|
C26H28Cl2N2O4
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0545006
|
3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C26H33ClN4O
|
1
|
| 1 |
Ki = 66 nM
|
|
|
|
CP0568683
|
4-N-[2-(1H-indol-3-yl)ethyl]-2-N-[2-(4-phenylpiperazin-1-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C25H31N9
|
1
|
| 1 |
Ki = 67 nM
|
|
|
|
CP0456102
|
1'-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C23H27ClN4O
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0891133
|
5-(3-(4-(4-chlorophenyl)piperazin-1-yl)propoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C24H27ClN2O3
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0473054
|
(1S,2R,6S,7R)-4-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C25H34ClN3O2
|
1
|
| 1 |
Ki = 73 nM
|
|
|
|
CP0386708
|
2-[4-[3-(8-acetyl-4-methyl-2-oxochromen-7-yl)oxypropyl]piperazin-1-yl]benzonitrile
Show/Hide
|
C26H27N3O4
|
1
|
| 1 |
Ki = 75 nM
|
|
|
|
CP0456104
|
1'-[2-[4-(4-fluorophenyl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C24H26FN3O
|
1
|
| 1 |
Ki = 75 nM
|
|
|
|
CP0466249
|
4-[(2R)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H31N5O2S
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0046273
|
2-methyl-4-[[1-(2-phenylethyl)piperidin-4-yl]methoxy]pyrrolo[3,4-c]quinoline
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0778940
|
N-[[1-[2-(4-Aminophenyl)ethyl]-4-piperidinyl]methyl]-1-isopropyl-1H-indazole-3-carboxamide dihydrochloride
Show/Hide
|
C25H35Cl2N5O
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0530032
|
(1S,2R,6S,7R)-4-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C25H34ClN3O2
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0487624
|
4-[(2S)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H31N5O2S
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0386712
|
2-[4-[4-(8-acetyl-4-methyl-2-oxochromen-7-yl)oxybutyl]piperazin-1-yl]benzonitrile
Show/Hide
|
C27H29N3O4
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0396073
|
4-[(2S)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H32N4O4S
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0429636
|
2-[6-(4-naphthalen-1-ylpiperazin-1-yl)hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C27H31N3O3S
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0510213
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-3-chloro-4-fluorobenzenesulfonamide
Show/Hide
|
C20H22ClFN4O3S
|
1
|
| 1 |
Ki = 98 nM
|
|
|
|
CP0778942
|
1-Isopropyl-N-[[1-(2-pyridin-2-ylethyl)-4-piperidinyl]methyl]-1Hindazole-3-carboxamide hydrochloride
Show/Hide
|
C24H32ClN5O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0922293
|
2-Isopropyl-4-[[1-(2-phenylethyl)-4-piperidinyl]methoxy]-2Hpyrrolo[3,4-c]quinoline hydrochloride
Show/Hide
|
C28H34ClN3O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0144741
|
4-[1-(benzenesulfonyl)indol-3-yl]-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C18H17ClN4O2S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0466085
|
8-acetyl-7-[3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C27H32N2O4
|
1
|
| 1 |
Ki = 102 nM
|
|
|
|
CP0877295
|
5-(3-(4-(3-methoxyphenyl)piperazin-1-yl)propoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C25H30N2O4
|
1
|
| 1 |
Ki = 106 nM
|
|
|
|
CP0552643
|
4-[1-(benzenesulfonyl)indol-3-yl]-5-ethyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C19H19ClN4O2S
|
1
|
| 1 |
Ki = 107 nM
|
|
|
|
CP0548414
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C24H26N4O3S
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0396619
|
5-[(2S)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C27H32N4O4S
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0869884
|
2-(4-(4-(4,7-dimethyl-2-oxo-2H-chromen-5-yloxy)butyl)piperazin-1-yl)benzonitrile
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
Ki = 112 nM
|
|
|
|
CP0852531
|
5-(4-(4-(2-fluorophenyl)piperazin-1-yl)butoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C25H29FN2O3
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0040250
|
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
Show/Hide
|
C21H25N3O2S
|
1
|
| 1 |
Ki = 120.23 nM
|
|
|
|
CP0416040
|
8-[5-(4-chloro-2-methoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
|
C19H24ClN3O4
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0386709
|
8-acetyl-7-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C27H32N2O5
|
1
|
| 1 |
Ki = 138 nM
|
|
|
|
CP0495706
|
3-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31Cl2N3O2S
|
1
|
| 1 |
Ki = 147 nM
|
|
|
|
CP0489016
|
8-acetyl-4-methyl-7-[4-[4-(4-nitrophenyl)piperazin-1-yl]butoxy]chromen-2-one
Show/Hide
|
C26H29N3O6
|
1
|
| 1 |
Ki = 155 nM
|
|
|
|
CP0530033
|
(1R,2S,6R,7S)-4-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C25H33Cl2N3O2
|
1
|
| 1 |
Ki = 161 nM
|
|
|
|
CP0852534
|
5-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C25H28Cl2N2O3
|
1
|
| 1 |
Ki = 167 nM
|
|
|
|
CP0317610
|
1,1-dioxo-2-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C24H28F3N3O3S
|
1
|
| 1 |
Ki = 167 nM
|
|
|
|
CP0483144
|
3-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H30Cl3N3O2S
|
1
|
| 1 |
Ki = 177 nM
|
|
|
|
CP0391600
|
1,1-dioxo-2-[6-(4-pyrimidin-2-ylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C21H27N5O3S
|
1
|
| 1 |
Ki = 183 nM
|
|
|
|
CP0903003
|
4,7-dimethyl-5-{4-[4-(3-methoxyphenyl)piperazin-1-yl]butoxy}coumarin
Show/Hide
|
C26H32N2O4
|
1
|
| 1 |
Ki = 184 nM
|
|
|
|
CP0525901
|
(1R,2S,6R,7S)-4-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C26H34F3N3O2
|
1
|
| 1 |
Ki = 189 nM
|
|
|
|
CP0443099
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H26N4O3S2
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0568128
|
6-[4-(3-chlorophenyl)piperazin-1-yl]hexylurea
Show/Hide
|
C17H27ClN4O
|
1
|
| 1 |
Ki = 195 nM
|
|
|
|
CP0382741
|
4-(4-methylpiperazin-1-yl)-6-(phenylsulfanylmethyl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H20N6S
|
1
|
| 1 |
Ki = 197 nM
|
|
|
|
CP0431612
|
4-[(4-chloro-3-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6O
|
1
|
| 1 |
Ki = 197 nM
|
|
|
|
CP0159501
|
4-[[1-[2-[4-(methoxymethyl)phenyl]ethyl]piperidin-4-yl]methoxy]-2-methylpyrrolo[3,4-c]quinoline
Show/Hide
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C28H33N3O2
|
1
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| 1 |
Ki = 199.53 nM
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CP0852533
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2-(4-(3-(4,7-dimethyl-2-oxo-2H-chromen-5-yloxy)propyl)piperazin-1-yl)benzonitrile
Show/Hide
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C25H27N3O3
|
1
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| 1 |
Ki = 200 nM
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CP0462115
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1,1-dioxo-2-[6-(4-quinolin-8-ylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
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C26H30N4O3S
|
1
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| 1 |
Ki = 205 nM
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CP0532000
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N-cyclohexyl-2-[4-[3-(5-fluoro-1H-indol-3-yl)propyl]piperazin-1-yl]-N-phenylacetamide
Show/Hide
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C29H37FN4O
|
1
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| 1 |
Ki = 206.71 nM
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CP0416732
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2-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C23H27Cl2N3O3S
|
1
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| 1 |
Ki = 209 nM
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CP0461296
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N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
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C22H25F3N4O4S
|
1
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| 1 |
Ki = 210 nM
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CP0384573
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1-[6-(4-quinolin-8-ylpiperazin-1-yl)hexyl]benzo[cd]indol-2-one
Show/Hide
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C30H32N4O
|
1
|
| 1 |
Ki = 222 nM
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CP0542763
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4-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-2-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
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C27H33Cl2N9
|
1
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| 1 |
Ki = 222 nM
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CP0545014
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2-[6-(4-naphthalen-1-ylpiperazin-1-yl)hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C26H31N5O
|
1
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| 1 |
Ki = 223 nM
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CP0391303
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4-[(2S)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C28H29ClN4O2S
|
1
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| 1 |
Ki = 238 nM
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CP0391293
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5-[(2S)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
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C27H31N5O2S
|
1
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| 1 |
Ki = 244 nM
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CP0483352
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3-[6-[4-(3,4-dichlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H30Cl3N3O2S
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1
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| 1 |
Ki = 251 nM
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CP0811793
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4-[[1-[2-(4-Aminophenyl)ethyl]-4-piperidinyl]methoxy]-2-methyl-2H-pyrrolo[3,4-c]quinoline hydrochloride
Show/Hide
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C26H31ClN4O
|
1
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| 1 |
Ki = 251.19 nM
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CP0545007
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3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene-2-thione
Show/Hide
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C26H33ClN4S
|
1
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| 1 |
Ki = 258 nM
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CP0412402
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1'-[2-[4-(4-fluorophenyl)piperidin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
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C24H28FN3O
|
1
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| 1 |
Ki = 259 nM
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CP0573071
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1-[(2,6-dimethylphenoxy)ethoxyethyl]-4-(2-methoxyphenyl)piperazine hydrochloride (5)
Show/Hide
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C23H32N2O3
|
1
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| 1 |
Ki = 264 nM
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CP0482089
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2-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C23H28ClN3O3S
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1
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| 1 |
Ki = 266 nM
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CP0412404
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1'-[2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
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C23H26Cl2N4O
|
1
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| 1 |
Ki = 270 nM
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CP0545009
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3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene 2,2-dioxide
Show/Hide
|
C25H33ClN4O2S
|
1
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| 1 |
Ki = 282 nM
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CP0471830
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2-[6-[4-(3,4-dichlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C23H27Cl2N3O3S
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1
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| 1 |
Ki = 283 nM
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CP0911941
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6-acetyl-4,7-dimethyl-5-(3-(4-(4-nitrophenyl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
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C26H29N3O6
|
1
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| 1 |
Ki = 286 nM
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CP0395877
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N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-3,4-dichlorobenzenesulfonamide
Show/Hide
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C20H22Cl2N4O3S
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1
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| 1 |
Ki = 290 nM
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CP0568317
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2-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C23H28F3N5O
|
1
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| 1 |
Ki = 291 nM
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CP0378964
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4-(4-chlorophenyl)sulfonyl-5-(3,4-dihydro-1H-isoquinolin-2-yl)-2-ethylsulfonyl-1,3-thiazole
Show/Hide
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C20H19ClN2O4S3
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2
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| 1 |
Ki = 296 nM
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| 2 |
Ki = 315 nM
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CP0408250
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5-[(2R)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
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C27H32N4O4S
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1
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| 1 |
Ki = 296 nM
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CP0432718
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2-[6-[4-(2-fluorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C23H28FN3O3S
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1
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| 1 |
Ki = 307 nM
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CP0311502
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1,1-dioxo-2-[6-(4-phenylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
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C23H29N3O3S
|
1
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| 1 |
Ki = 321 nM
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CP0416668
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3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31Cl2N3O2S
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1
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| 1 |
Ki = 322 nM
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CP0576365
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1-(3-chlorophenyl)-4-[6-(sulfamoylamino)hexyl]piperazine
Show/Hide
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C16H27ClN4O2S
|
1
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| 1 |
Ki = 329 nM
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CP0417067
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2-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
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C29H33N3O3
|
1
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| 1 |
Ki = 334 nM
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CP0417090
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2-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
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C29H33N3O3
|
1
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| 1 |
Ki = 337 nM
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CP0459145
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2-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C24H31N3O4S
|
1
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| 1 |
Ki = 342 nM
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CP0456106
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1'-[2-[4-(4-chlorophenoxy)piperidin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
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C24H28ClN3O2
|
1
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| 1 |
Ki = 343 nM
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CP0542758
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2-N-[2-(1H-indol-3-yl)ethyl]-4-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
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C28H37N9O
|
1
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| 1 |
Ki = 344 nM
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CP0456103
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1'-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
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C23H27ClN4O
|
1
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| 1 |
Ki = 351 nM
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CP0432719
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2-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C23H28ClN3O3S
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1
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| 1 |
Ki = 361 nM
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CP0402058
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4-(4-methylpiperazin-1-yl)-6-(1-phenylselanylethyl)-1,3,5-triazin-2-amine
Show/Hide
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C16H22N6Se
|
1
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| 1 |
Ki = 376 nM
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CP0384693
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3-[6-[4-(2-fluorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31ClFN3O2S
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1
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| 1 |
Ki = 376 nM
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CP0416052
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4-[(2R)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C27H32N4O4S
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1
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| 1 |
Ki = 390 nM
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CP0383941
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8-[5-(2,4-dimethoxy-5-phenylphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C26H31N3O5
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1
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| 1 |
Ki = 398.11 nM
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CP0416079
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8-acetyl-7-[4-[4-(3-fluorophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
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C26H29FN2O4
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1
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| 1 |
Ki = 400 nM
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CP0456105
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1'-[2-[4-(4-chlorophenyl)piperidin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C24H28ClN3O
|
1
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| 1 |
Ki = 404 nM
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CP0382740
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4-(4-methylpiperazin-1-yl)-6-(phenylselanylmethyl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H20N6Se
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1
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| 1 |
Ki = 406 nM
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CP0417077
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1-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
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C27H30Cl3N3O
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1
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| 1 |
Ki = 406 nM
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CP0402157
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4-[1-(2-chlorophenyl)sulfanylethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H21ClN6S
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1
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| 1 |
Ki = 407 nM
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CP0416078
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8-acetyl-7-[3-[4-(3-fluorophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H27FN2O4
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1
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| 1 |
Ki = 408 nM
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CP0486987
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N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C22H24N4O3S2
|
1
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| 1 |
Ki = 410 nM
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CP0301336
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N-[[4-[5-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]pentoxy]phenyl]methyl]-N-methylprop-2-yn-1-amine
Show/Hide
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C34H40N4O3S
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1
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| 1 |
Ki = 420 nM
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CP0483353
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1-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31Cl2N3O
|
1
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| 1 |
Ki = 423 nM
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CP0478414
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1-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31Cl2N3O
|
1
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| 1 |
Ki = 429 nM
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CP0402158
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4-(4-methylpiperazin-1-yl)-6-[(5-methyl-2-propan-2-ylphenoxy)methyl]-1,3,5-triazin-2-amine
Show/Hide
|
C19H28N6O
|
1
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| 1 |
Ki = 430 nM
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CP0569767
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2-[6-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C24H31N5O3
|
1
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| 1 |
Ki = 434 nM
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CP0073332
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2-ethyl-3-[(3-fluorophenyl)methyl]-7-piperazin-1-ylimidazo[4,5-b]pyridine
Show/Hide
|
C19H22FN5
|
1
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| 1 |
Ki = 441 nM
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CP0417065
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3-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C25H30N4O2S
|
1
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| 1 |
Ki = 443 nM
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CP0417452
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3-[(3-chlorophenyl)methyl]-2-ethyl-7-piperazin-1-ylimidazo[4,5-b]pyridine
Show/Hide
|
C19H22ClN5
|
1
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| 1 |
Ki = 449 nM
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CP0445925
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5-[(2R)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C27H31N5O2S
|
1
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| 1 |
Ki = 451 nM
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CP0456107
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1'-[2-[4-(2-chlorophenyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C23H27ClN4O
|
1
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| 1 |
Ki = 452 nM
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CP0417068
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3-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C27H36N4O2
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1
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| 1 |
Ki = 456 nM
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CP0384574
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2-[6-[4-(2-ethoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C30H35N3O3
|
1
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| 1 |
Ki = 461 nM
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CP0864704
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5-(4-(4-(4-chlorophenyl)piperazin-1-yl)butoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C25H29ClN2O3
|
1
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| 1 |
Ki = 465 nM
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CP0569927
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2-[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
|
C23H28Cl2N6
|
1
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| 1 |
Ki = 470 nM
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CP0389653
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3-[(3-fluorophenyl)methyl]-7-piperazin-1-yl-2-propan-2-ylimidazo[4,5-b]pyridine
Show/Hide
|
C20H24FN5
|
1
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| 1 |
Ki = 475 nM
|
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CP0159262
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5-methyl-4-(1-naphthalen-1-ylsulfonylindol-3-yl)-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C22H19ClN4O2S
|
1
|
| 1 |
Ki = 490 nM
|
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CP0416667
|
1-[6-[4-(3,4-dichlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H30Cl3N3O
|
1
|
| 1 |
Ki = 493 nM
|
|
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CP0545013
|
2-[[4-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]cyclohexyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C24H30ClN5O
|
1
|
| 1 |
Ki = 493 nM
|
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CP0485159
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1'-[2-(4-phenylpiperazin-1-yl)ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C23H28N4O
|
1
|
| 1 |
Ki = 496 nM
|
|
|
|
CP0862350
|
6-acetyl-5-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C28H34N2O5
|
1
|
| 1 |
Ki = 520 nM
|
|
|
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CP0384691
|
1-[6-[4-(2-fluorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31ClFN3O
|
1
|
| 1 |
Ki = 524 nM
|
|
|
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CP0569187
|
4-(3-chlorophenyl)-N-[6-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2-yl)hexyl]piperazine-1-carboxamide
Show/Hide
|
C23H29ClN6O2
|
1
|
| 1 |
Ki = 530 nM
|
|
|
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CP0417091
|
3-[6-[4-(2-nitrophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C26H30N4O4S
|
1
|
| 1 |
Ki = 533 nM
|
|
|
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CP0416669
|
1-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31Cl2N3O
|
1
|
| 1 |
Ki = 540 nM
|
|
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CP0525902
|
(1S,2R,6S,7R)-4-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C25H34ClN3O2
|
1
|
| 1 |
Ki = 541 nM
|
|
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|
CP0495707
|
3-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31Cl2N3O2S
|
1
|
| 1 |
Ki = 548 nM
|
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CP0541083
|
2-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
Ki = 563 nM
|
|
|
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CP0483351
|
3-[6-[4-(2-ethoxyphenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C28H35N3O3S
|
1
|
| 1 |
Ki = 578 nM
|
|
|
|
CP0382746
|
4-[1-(3-chlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6O
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0478413
|
3-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C27H31ClF3N3O2S
|
1
|
| 1 |
Ki = 596 nM
|
|
|
|
CP0055944
|
N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C27H31F3N4O7S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0417069
|
1-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
|
C28H33N3O2
|
1
|
| 1 |
Ki = 652 nM
|
|
|
|
CP0424446
|
4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-ethyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C20H21ClN4O3S
|
1
|
| 1 |
Ki = 661 nM
|
|
|
|
CP0489725
|
4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C19H19ClN4O3S
|
1
|
| 1 |
Ki = 676 nM
|
|
|
|
CP0417454
|
3-[(3-chlorophenyl)methyl]-7-piperazin-1-yl-2-propan-2-ylimidazo[4,5-b]pyridine
Show/Hide
|
C20H24ClN5
|
1
|
| 1 |
Ki = 694 nM
|
|
|
|
CP0383204
|
1'-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
Show/Hide
|
C24H29ClN4O
|
1
|
| 1 |
Ki = 715 nM
|
|
|
|
CP0417089
|
1-[6-[4-(2-ethoxyphenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
|
C29H35N3O2
|
1
|
| 1 |
Ki = 717 nM
|
|
|
|
CP0384692
|
1-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C28H31ClF3N3O
|
1
|
| 1 |
Ki = 773 nM
|
|
|
|
CP0473055
|
(1R,2S,6R,7S)-4-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C26H37N3O3
|
1
|
| 1 |
Ki = 785 nM
|
|
|
|
CP0159204
|
5-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C18H17ClN4O3S
|
1
|
| 1 |
Ki = 794 nM
|
|
|
|
CP0404364
|
4-cyano-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
|
C27H31N5O7S
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0409618
|
4-chloro-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
|
C26H31ClN4O7S
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0445897
|
2-[2-[4-[(2-methylpyrrolo[3,4-c]quinolin-4-yl)oxymethyl]piperidin-1-yl]ethyl]benzoic acid
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0519609
|
5-[1-(benzenesulfonyl)indol-3-yl]-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C17H15ClN4O2S
|
1
|
| 1 |
Ki = 891 nM
|
|
|
|
CP0384570
|
1-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]benzo[cd]indol-2-one
Show/Hide
|
C26H30N4O
|
1
|
| 1 |
Ki = 892 nM
|
|
|
|
CP0469370
|
1,1-dioxo-2-[6-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C24H28F3N3O3S
|
1
|
| 1 |
Ki = 922 nM
|
|
|
|
CP0497340
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C21H23F3N4O4S
|
1
|
| 1 |
Ki = 950 nM
|
|
|
|
CP0447212
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]thiophene-2-sulfonamide
Show/Hide
|
C18H22N4O3S2
|
1
|
| 1 |
Ki = 970 nM
|
|
|
|
CP0448988
|
N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C27H31F3N4O8S
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0917665
|
1-Isopropyl-N-[[1-[2-(4-nitrophenyl)ethyl]-4-piperidinyl]methyl]-1H-indazole-3-carboxamide oxalate
Show/Hide
|
C27H33N5O7
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0566208
|
4-(5-methoxy-1-naphthalen-2-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C23H21ClN4O3S
|
1
|
| 1 |
Ki = 1047 nM
|
|
|
|
CP0545010
|
2-[[4-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C24H24ClN5O
|
1
|
| 1 |
Ki = 1067 nM
|
|
|
|
CP0420831
|
4-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C19H18ClFN4O3S
|
1
|
| 1 |
Ki = 1122 nM
|
|
|
|
CP0476721
|
5-[(2R)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C28H29ClN4O2S
|
1
|
| 1 |
Ki = 1150 nM
|
|
|
|
CP0489018
|
8-acetyl-4-methyl-7-[4-(4-pyrazin-2-ylpiperazin-1-yl)butoxy]chromen-2-one
Show/Hide
|
C24H28N4O4
|
1
|
| 1 |
Ki = 1158 nM
|
|
|
|
CP0438428
|
4-[1-(benzenesulfonyl)indol-6-yl]-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C18H17ClN4O2S
|
1
|
| 1 |
Ki = 1175 nM
|
|
|
|
CP0395878
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-5-fluoro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H25FN4O3S2
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0144745
|
4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-N-(2,2-difluoroethyl)-5-methyl-1H-imidazol-2-amine
Show/Hide
|
C21H20F2N4O3S
|
1
|
| 1 |
Ki = 1230 nM
|
|
|
|
CP0432270
|
N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-propan-2-ylbenzenesulfonamide
Show/Hide
|
C29H38N4O7S
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0432567
|
1,1-dioxo-2-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C22H28N4O3S
|
1
|
| 1 |
Ki = 1290 nM
|
|
|
|
CP0576876
|
2-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
|
C22H26Cl2N6
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0396072
|
5-[(2S)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C28H29ClN4O2S
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0545011
|
2-[[4-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C24H24ClN5O
|
1
|
| 1 |
Ki = 1450 nM
|
|
|
|
CP0568014
|
2-N-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C20H32N8O
|
1
|
| 1 |
Ki = 1455 nM
|
|
|
|
CP0416670
|
1-[6-[4-(4-bromophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31BrClN3O
|
1
|
| 1 |
Ki = 1490 nM
|
|
|
|
CP0417076
|
3-[6-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C27H31ClF3N3O2S
|
1
|
| 1 |
Ki = 1526 nM
|
|
|
|
CP0864709
|
6-acetyl-4,7-dimethyl-5-(4-(4-(pyridin-4-yl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
|
C26H31N3O4
|
1
|
| 1 |
Ki = 1595 nM
|
|
|
|
CP0435403
|
4-(5-methoxy-1-naphthalen-1-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C23H21ClN4O3S
|
1
|
| 1 |
Ki = 1660 nM
|
|
|
|
CP0421839
|
3-(3-ethylimidazol-4-yl)-4,5-difluoro-1H-indole
Show/Hide
|
C13H11F2N3
|
1
|
| 1 |
Ki = 1698 nM
|
|
|
|
CP0569537
|
[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C24H30Cl2N4O
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0417075
|
1-[6-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C28H31ClF3N3O
|
1
|
| 1 |
Ki = 1766 nM
|
|
|
|
CP0576950
|
[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]piperazin-1-yl]-(1-methylindazol-3-yl)methanone
Show/Hide
|
C25H30Cl2N6O
|
1
|
| 1 |
Ki = 1800 nM
|
|
|
|
CP0402156
|
4-[1-(2-chlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6O
|
1
|
| 1 |
Ki = 1830 nM
|
|
|
|
CP0396618
|
4-[(2R)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C28H29ClN4O2S
|
1
|
| 1 |
Ki = 1904 nM
|
|
|
|
CP0519608
|
4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-N-(2-phenylethyl)-1H-imidazol-2-amine
Show/Hide
|
C27H26N4O3S
|
1
|
| 1 |
Ki = 1905 nM
|
|
|
|
CP0495705
|
2-[6-[4-(2-nitrophenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C28H30N4O4
|
1
|
| 1 |
Ki = 1918 nM
|
|
|
|
CP0384571
|
1-[6-[4-(4-methoxyphenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
|
C28H33N3O2
|
1
|
| 1 |
Ki = 1927 nM
|
|
|
|
CP0390940
|
4-[4-[2-[(2R)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
Show/Hide
|
C26H29N5O4S
|
1
|
| 1 |
Ki = 1970 nM
|
|
|
|
CP0430675
|
N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-methoxybenzenesulfonamide
Show/Hide
|
C27H34N4O8S
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0492835
|
3-chloro-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
|
C26H31ClN4O7S
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0396620
|
4-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
Show/Hide
|
C26H29N5O4S
|
1
|
| 1 |
Ki = 2040 nM
|
|
|
|
CP0568316
|
2-[6-(4-quinolin-8-ylpiperazin-1-yl)hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C25H30N6O
|
1
|
| 1 |
Ki = 2196 nM
|
|
|
|
CP0402155
|
4-[(3-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H22N6O
|
1
|
| 1 |
Ki = 2274 nM
|
|
|
|
CP0435404
|
5-[1-(benzenesulfonyl)indol-4-yl]-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C17H15ClN4O2S
|
1
|
| 1 |
Ki = 2291 nM
|
|
|
|
CP0864705
|
4,7-dimethyl-5-(4-(4-(pyrazin-2-yl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
|
CP0574555
|
[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]piperazin-1-yl]-pyridin-2-ylmethanone
Show/Hide
|
C23H29Cl2N5O
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
|
CP0519973
|
8-acetyl-4-methyl-7-[3-(4-pyridin-4-ylpiperazin-1-yl)propoxy]chromen-2-one
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
Ki = 2434 nM
|
|
|
|
CP0472438
|
4-[4-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
Show/Hide
|
C26H29N5O4S
|
1
|
| 1 |
Ki = 2453 nM
|
|
|
|
CP0547877
|
4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-1,3-thiazol-2-amine
Show/Hide
|
C19H17N3O3S2
|
1
|
| 1 |
Ki = 2455 nM
|
|
|
|
CP0857137
|
6-acetyl-4,7-dimethyl-5-(4-(4-(pyrazin-2-yl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
|
C25H30N4O4
|
1
|
| 1 |
Ki = 2500 nM
|
|
|
|
CP0376691
|
N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-methylbenzenesulfonamide
Show/Hide
|
C27H34N4O7S
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0390364
|
8-acetyl-4-methyl-7-(3-morpholin-4-ylpropoxy)chromen-2-one
Show/Hide
|
C19H23NO5
|
1
|
| 1 |
Ki = 2542 nM
|
|
|
|
CP0542765
|
2-N-[4-(4-phenylpiperazin-1-yl)butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C17H26N8
|
1
|
| 1 |
Ki = 2619 nM
|
|
|
|
CP0382745
|
4-(4-methylpiperazin-1-yl)-6-(phenoxymethyl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H20N6O
|
1
|
| 1 |
Ki = 2628 nM
|
|
|
|
CP0575067
|
2-N-[2-(2,3-dichlorophenoxy)ethyl]-4-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C21H21Cl2N7O
|
1
|
| 1 |
Ki = 2637 nM
|
|
|
|
CP0871828
|
6-acetyl-5-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C27H30Cl2N2O4
|
1
|
| 1 |
Ki = 2650 nM
|
|
|
|
CP0497344
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]thiophene-2-sulfonamide
Show/Hide
|
C19H24N4O3S2
|
1
|
| 1 |
Ki = 2700 nM
|
|
|
|
CP0542760
|
2-N-[2-(1H-indol-3-yl)ethyl]-4-N-[2-(2-methoxyphenyl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 2749 nM
|
|
|
|
CP0862349
|
6-acetyl-4,7-dimethyl-5-(3-(4-(pyrazin-2-yl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
|
C24H28N4O4
|
1
|
| 1 |
Ki = 3000 nM
|
|
|
|
CP0384762
|
N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
|
C26H32N4O7S
|
1
|
| 1 |
Ki = 3162.28 nM
|
|
|
|
CP0338298
|
N-[4-[2-[4-[(2-methylpyrrolo[3,4-c]quinolin-4-yl)oxymethyl]piperidin-1-yl]ethyl]phenyl]acetamide
Show/Hide
|
C28H32N4O2
|
1
|
| 1 |
Ki = 3162.28 nM
|
|
|
|
CP0476616
|
5-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-1-(2,2-difluoroethyl)-4-methylimidazol-2-amine
Show/Hide
|
C21H20F2N4O3S
|
1
|
| 1 |
Ki = 3236 nM
|
|
|
|
CP0542757
|
2-N-[6-(4-phenylpiperazin-1-yl)hexyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C19H30N8
|
1
|
| 1 |
Ki = 3265 nM
|
|
|
|
CP0447126
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
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C21H23N5O3S2
|
1
|
| 1 |
Ki = 3300 nM
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CP0379115
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10-[(4-chloro-2-fluorophenyl)methyl]phenothiazine 5,5-dioxide
Show/Hide
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C19H13ClFNO2S
|
1
|
| 1 |
Ki = 3866 nM
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CP0417066
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1-[6-[4-(2-nitrophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
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C27H30N4O3
|
1
|
| 1 |
Ki = 3983 nM
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CP0510210
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N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
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C21H26N4O3S
|
1
|
| 1 |
Ki = 4200 nM
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CP0417078
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1-[6-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C28H31ClF3N3O
|
1
|
| 1 |
Ki = 4354 nM
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CP0542994
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2-N-[5-(4-phenylpiperazin-1-yl)pentyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C18H28N8
|
1
|
| 1 |
Ki = 4408 nM
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CP0891132
|
6-acetyl-4,7-dimethyl-5-(4-morpholinobutoxy)-2H-chromen-2-one
Show/Hide
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C21H27NO5
|
1
|
| 1 |
Ki = 4460 nM
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CP0857134
|
4,7-dimethyl-5-(3-(4-(pyrazin-2-yl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
|
C22H26N4O3
|
1
|
| 1 |
Ki = 4565 nM
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CP0438423
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2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-3-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidine;hydrochloride
Show/Hide
|
C22H23ClN4O3S
|
1
|
| 1 |
Ki = 5129 nM
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CP0400005
|
5-chloro-2-(3,4-dihydro-1H-isoquinolin-2-yl)-4-(4-methylphenyl)sulfonyl-1,3-thiazole
Show/Hide
|
C19H17ClN2O2S2
|
1
|
| 1 |
Ki = 5192 nM
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CP0400395
|
3-(4-chlorophenyl)sulfonyl-1-(2-methoxyethyl)-4,5-dimethylpyrrol-2-amine
Show/Hide
|
C15H19ClN2O3S
|
1
|
| 1 |
Ki = 5264 nM
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CP0571682
|
2-[4-[3-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
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C22H25N5O2
|
1
|
| 1 |
Ki = 5300 nM
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CP0544200
|
4-N-[2-(2,3-dichlorophenyl)ethyl]-2-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C21H21Cl2N7
|
1
|
| 1 |
Ki = 5967 nM
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CP0395880
|
N-[4-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-1,3-benzothiazole-4-sulfonamide
Show/Hide
|
C22H25N5O3S2
|
1
|
| 1 |
Ki = 6100 nM
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CP0577590
|
phenyl-[4-[3-(4-phenylpiperazin-1-yl)propyl]piperazin-1-yl]methanone
Show/Hide
|
C24H32N4O
|
1
|
| 1 |
Ki = 6500 nM
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CP0542761
|
2-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C19H30N8O
|
1
|
| 1 |
Ki = 6521 nM
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CP0418579
|
2-(benzenesulfonyl)-4,6-diphenylthieno[2,3-b]pyridin-3-amine
Show/Hide
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C25H18N2O2S2
|
1
|
| 1 |
Ki = 6836 nM
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CP0568818
|
7-[4-[4-(pyridine-2-carbonyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
Ki = 6900 nM
|
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CP0569926
|
2-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
Ki = 7400 nM
|
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CP0493761
|
N-[4-[1-(benzenesulfonyl)indol-6-yl]-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki = 7413 nM
|
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CP0544198
|
6-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4-diamine
Show/Hide
|
C23H24Cl2N8
|
1
|
| 1 |
Ki = 7910 nM
|
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CP0435405
|
N-[4-[1-(benzenesulfonyl)-5-fluoroindol-3-yl]-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C21H19FN4O3S
|
1
|
| 1 |
Ki = 7943 nM
|
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CP0573228
|
[4-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]piperazin-1-yl]-(1-methylindazol-3-yl)methanone
Show/Hide
|
C26H34N6O2
|
1
|
| 1 |
Ki = 8300 nM
|
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CP0421837
|
3-(3-ethylimidazol-4-yl)-7-fluoro-5-iodo-1H-indole
Show/Hide
|
C13H11FIN3
|
1
|
| 1 |
Ki = 8511 nM
|
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CP0426679
|
4,5-difluoro-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H9F2N3
|
1
|
| 1 |
Ki = 8913 nM
|
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CP0421835
|
5-bromo-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H10BrN3
|
1
|
| 1 |
Ki = 9333 nM
|
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CP0569637
|
2-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C18H28N8O
|
1
|
| 1 |
Ki = 9581 nM
|
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CP0046312
|
4-[2-[4-[[(1-propan-2-ylindazole-3-carbonyl)amino]methyl]piperidin-1-yl]ethyl]benzoic acid
Show/Hide
|
C26H32N4O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
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CP0046314
|
4-[2-[4-[(2-methylpyrrolo[3,4-c]quinolin-4-yl)oxymethyl]piperidin-1-yl]ethyl]benzoic acid
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
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CP0768837
|
2-Methyl-4-[[1-(2-morpholin-4-ylethyl)-4-piperidinyl]methoxy]-2H-pyrrolo[3,4-c]quinoline hydrochloride
Show/Hide
|
C24H33ClN4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0497341
|
N-[3-[4-(1,2-benzoxazol-3-yl)piperazin-1-yl]propyl]-6-chloronaphthalene-2-sulfonamide
Show/Hide
|
C24H25ClN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0489017
|
8-acetyl-4-methyl-7-(4-morpholin-4-ylbutoxy)chromen-2-one
Show/Hide
|
C20H25NO5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0852529
|
6-acetyl-4,7-dimethyl-5-[3-(morpholin-4-yl)propoxy]coumarin
Show/Hide
|
C20H25NO5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0852530
|
4,7-dimethyl-5-(4-(4-(4-nitrophenyl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
|
C25H29N3O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0857132
|
4,7-dimethyl-5-(3-(4-(4-nitrophenyl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
|
C24H27N3O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0864707
|
6-acetyl-4,7-dimethyl-5-(3-(4-(pyridin-4-yl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
|
C25H29N3O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0869881
|
4,7-dimethyl-5-(4-morpholinobutoxy)-2H-chromen-2-one
Show/Hide
|
C19H25NO4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0905188
|
4,7-dimethyl-5-(3-morpholinopropoxy)-2H-chromen-2-one
Show/Hide
|
C18H23NO4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0423253
|
N-[4-[1-(benzenesulfonyl)indol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
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CP0424448
|
N-[4-[1-(benzenesulfonyl)indol-3-yl]-5-ethyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0424449
|
N-[4-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C22H21FN4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0435386
|
N-[4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C21H20N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0435391
|
2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-3-methyl-1H-imidazo[1,2-a]pyrimidin-4-ium;bromide
Show/Hide
|
C22H19BrN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0435398
|
N-[4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]-2-phenylacetamide
Show/Hide
|
C27H24N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0435400
|
N-[4-[1-(benzenesulfonyl)-5-fluoroindol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H17FN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435406
|
N-[4-(5-methoxy-1-naphthalen-1-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C25H22N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0438422
|
N-[5-methyl-4-(1-naphthalen-1-ylsulfonylindol-3-yl)-1H-imidazol-2-yl]propanamide
Show/Hide
|
C25H22N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0438427
|
N-[4-(5-methoxy-1-naphthalen-2-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C25H22N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440887
|
1-[3-[1-(benzenesulfonyl)indol-3-yl]-2-methyl-6,7-dihydro-5H-imidazo[1,2-a]pyrimidin-8-yl]ethanone
Show/Hide
|
C23H22N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440888
|
2-[1-(benzenesulfonyl)indol-3-yl]-1H-imidazo[1,2-a]pyrimidin-4-ium;bromide
Show/Hide
|
C20H15BrN4O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0476615
|
1-[5-[1-(benzenesulfonyl)indol-3-yl]-6-methyl-2,3-dihydroimidazo[1,2-a]imidazol-1-yl]ethanone
Show/Hide
|
C22H20N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489684
|
N-[4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-ethyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C22H22N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489726
|
N-[5-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H17FN4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0519613
|
N-[4-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C21H19FN4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0519614
|
2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-3-methyl-1H-imidazo[1,2-a]pyridin-4-ium;bromide
Show/Hide
|
C23H20BrN3O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0521240
|
N-[4-[1-(benzenesulfonyl)indol-6-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0521248
|
N-[4-[1-(benzenesulfonyl)indol-4-yl]-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0538216
|
N-[4-(5-methoxy-1-naphthalen-2-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C26H24N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0098968
|
3-(3-ethylimidazol-4-yl)-1H-indole-5-carboxamide
Show/Hide
|
C14H14N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0413064
|
3-(3-ethylimidazol-4-yl)-5-iodo-1H-indole
Show/Hide
|
C13H12IN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0757055
|
3-(1-methyl-1H-imidazol-5-yl)-1H-indole-5-carboxamide
Show/Hide
|
C13H12N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0859942
|
3-(1-ethyl-1H-imidazol-5-yl)-1H-indole-5-sulfonamide
Show/Hide
|
C13H14N4O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0900183
|
methyl 3-(1-ethyl-1H-imidazol-5-yl)-1H-indole-5-carboxylate
Show/Hide
|
C15H15N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0344919
|
3-(3-ethylimidazol-4-yl)-4-fluoro-5-iodo-1H-indole
Show/Hide
|
C13H11FIN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421663
|
5-chloro-3-(3-ethylimidazol-4-yl)-6-fluoro-1H-indole
Show/Hide
|
C13H11ClFN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421833
|
5-ethoxy-3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421836
|
3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole-5-carboxamide
Show/Hide
|
C14H13FN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421838
|
3-(3-ethylimidazol-4-yl)-5-fluoro-1H-indole
Show/Hide
|
C13H12FN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440388
|
3-(3-ethylimidazol-4-yl)-5-methyl-1H-indole
Show/Hide
|
C14H15N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440390
|
5-chloro-3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H12ClN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440391
|
5-bromo-3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H12BrN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440392
|
5-iodo-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H10IN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0528449
|
5-bromo-4-fluoro-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H9BrFN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0528508
|
3-(3-ethylimidazol-4-yl)-5-methoxy-1H-indole
Show/Hide
|
C14H15N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0528509
|
3-(3-ethylimidazol-4-yl)-4-fluoro-5-methoxy-1H-indole
Show/Hide
|
C14H14FN3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0528510
|
5-chloro-3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole
Show/Hide
|
C13H11ClFN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0528511
|
4-fluoro-5-methoxy-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H12FN3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0530508
|
3-(3-ethylimidazol-4-yl)-5-(trifluoromethyl)-1H-indole
Show/Hide
|
C14H12F3N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0537948
|
4-fluoro-3-(3-methylimidazol-4-yl)-1H-indole-5-carboxamide
Show/Hide
|
C13H11FN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0541120
|
5-chloro-4-fluoro-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H9ClFN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0541121
|
3-(3-ethylimidazol-4-yl)-6-fluoro-1H-indole
Show/Hide
|
C13H12FN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0541126
|
3-(3-ethylimidazol-4-yl)-5-(trifluoromethoxy)-1H-indole
Show/Hide
|
C14H12F3N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0553532
|
3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H13N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0562326
|
3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole
Show/Hide
|
C13H12FN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0000082
|
CAS_68647
Show/Hide
|
C18H19N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0379116
|
3-(benzenesulfonyl)-6-chloro-N-(4-methylphenyl)quinolin-4-amine
Show/Hide
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C22H17ClN2O2S
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1
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| 1 |
Ki = 10150 nM
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CP0575068
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2-N-[2-(1H-indol-3-yl)ethyl]-6-(4-phenylpiperazin-1-yl)-1,3,5-triazine-2,4-diamine
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C23H26N8
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1
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| 1 |
Ki = 10640 nM
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CP0542995
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2-N-(2-anilinoethyl)-4-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
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C21H24N8
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1
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| 1 |
Ki = 11050 nM
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CP0431611
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4-[(2-chlorophenyl)sulfonylmethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
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C15H19ClN6O2S
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1
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| 1 |
Ki = 11590 nM
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CP0568664
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4-N-[2-(1H-indol-3-yl)ethyl]-2-N-[2-(2-methoxyphenoxy)ethyl]-1,3,5-triazine-2,4,6-triamine
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C22H25N7O2
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1
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| 1 |
Ki = 12830 nM
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CP0543606
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2-[4-[3-(4-phenylpiperazin-1-yl)propyl]piperazin-1-yl]pyridine-3-carbonitrile
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C23H30N6
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1
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| 1 |
Ki = 13000 nM
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CP0542759
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4-N-[2-(1H-indol-3-yl)ethyl]-2-N-[2-(2-methoxyanilino)ethyl]-1,3,5-triazine-2,4,6-triamine
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C22H26N8O
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1
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| 1 |
Ki = 14390 nM
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CP0379117
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1-[3-(benzenesulfonyl)-6-chloroquinolin-4-yl]piperidine-4-carboxamide
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C21H20ClN3O3S
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1
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| 1 |
Ki = 14960 nM
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CP0481865
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N-(5-chloro-2-methylphenyl)-2-(2,4-difluorophenyl)-N-methyl-1-oxoisoquinoline-4-carboxamide
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C24H17ClF2N2O2
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1
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| 1 |
Ki = 14980 nM
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CP0400394
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5'-Chloro-1H,1''H-[3,3':3',3''-terindol]-2'(1'H)-one (4c)
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C24H16ClN3O
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2
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| 1 |
Ki = 15830 nM
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| 2 |
Ki = 18340 nM
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CP0382743
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4-[(2-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
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C16H22N6O
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1
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| 1 |
Ki = 17170 nM
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CP0456108
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1'-[2-[4-(4-chlorobenzoyl)piperazin-1-yl]ethyl]spiro[1H-indole-3,3'-pyrrolidine]-2-one
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C24H27ClN4O2
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1
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| 1 |
Ki = 17330 nM
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CP0384209
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4-chloro-N-(2-isoquinolin-1-ylphenyl)benzenesulfonamide
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C21H15ClN2O2S
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1
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| 1 |
Ki = 18130 nM
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CP0544199
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2-N-[2-(2,3-dichloroanilino)ethyl]-4-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
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C21H22Cl2N8
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1
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| 1 |
Ki = 18190 nM
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CP0379113
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5-bromo-N-[1-(naphthalen-1-ylmethyl)pyrazol-3-yl]thiophene-2-sulfonamide
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C18H14BrN3O2S2
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1
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| 1 |
Ki = 18570 nM
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CP0569929
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2-[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
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C24H32N6O
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1
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| 1 |
Ki = 23000 nM
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CP0400006
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4-benzyl-12-bromo-1,4-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-9(16),10(15),11,13-tetraene
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C21H21BrN2
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1
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| 1 |
Ki = 25120 nM
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CP0523197
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2-(4-fluorophenyl)sulfonyl-1-(1H-indol-3-yl)-3H-isoquinoline
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C23H17FN2O2S
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1
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| 1 |
Ki = 26540 nM
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CP0413125
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5-(6-oxo-1H-pyridazin-3-yl)-N-(5,6,7,8-tetrahydronaphthalen-1-yl)thiophene-2-sulfonamide
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C18H17N3O3S2
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1
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| 1 |
Ki = 26780 nM
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CP0542764
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2-N-[2-(1H-indol-3-yl)ethyl]-6-[4-(2-methoxyphenyl)piperazin-1-yl]-1,3,5-triazine-2,4-diamine
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C24H28N8O
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1
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| 1 |
Ki = 27660 nM
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CP0418580
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N-(3-chlorophenyl)-2-(3-methoxyphenyl)-N-methyl-1-oxoisoquinoline-4-carboxamide
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C24H19ClN2O3
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1
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| 1 |
Ki = 28980 nM
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CP0056178
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4-fluoranyl-N-(4-oxidanyl-3-quinolin-8-ylsulfanyl-naphthalen-1-yl)benzenesulfonamide
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C25H17FN2O3S2
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1
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| 1 |
Ki = 29190 nM
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CP0569536
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[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]piperazin-1-yl]-phenylmethanone
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C25H34N4O2
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1
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| 1 |
Ki = 30000 nM
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CP0576951
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[4-[3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl]piperazin-1-yl]-phenylmethanone
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C25H34N4O2
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1
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| 1 |
Ki = 30000 nM
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CP0504617
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4-[(4-chlorophenyl)methylsulfanyl]-6-fluoro-3-(4-methylphenyl)sulfonylquinoline
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C23H17ClFNO2S2
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1
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| 1 |
Ki = 31010 nM
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CP0908603
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1-(1H-indol-3-yl)-2-(phenylsulfonyl)-1,2-dihydroisoquinoline
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C23H18N2O2S
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1
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| 1 |
Ki = 31530 nM
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CP0545394
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4-(3-chlorophenyl)piperazine-1-carboxamide
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C11H14ClN3O
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1
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| 1 |
Ki = 32360 nM
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CP0400393
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N-[(E)-(6-chloro-2,3,4,9-tetrahydrocarbazol-1-ylidene)amino]-4-methylbenzenesulfonamide
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C19H18ClN3O2S
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1
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| 1 |
Ki = 32700 nM
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CP0504618
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N-(10a-morpholin-4-yl-7,8,9,10-tetrahydro-6bH-naphtho[1,2-b][1]benzofuran-5-yl)benzenesulfonamide
Show/Hide
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C26H28N2O4S
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1
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| 1 |
Ki = 33870 nM
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CP0147070
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N-(4-hydroxy-3-quinolin-8-ylsulfanylnaphthalen-1-yl)benzenesulfonamide
Show/Hide
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C25H18N2O3S2
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1
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| 1 |
Ki = 34220 nM
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CP0580053
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazine-2-carboxamide
Show/Hide
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C19H25N5O2
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1
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| 1 |
Ki = 35800 nM
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CP0573200
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2-[4-[3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
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C24H32N6O
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1
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| 1 |
Ki = 40000 nM
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CP0417063
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2-[6-[4-(4-methoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
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C29H33N3O3
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1
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| 1 |
Ki = 60100 nM
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CP0500281
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N-[[1-methyl-1-(2-phenylethyl)piperidin-1-ium-4-yl]methyl]-1-propan-2-ylindazole-3-carboxamide;iodide
Show/Hide
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C26H35IN4O
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1
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| 1 |
Ki > 1000 nM
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CP0524042
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4-[(1-butylpiperidin-4-yl)methoxy]-2-methylpyrrolo[3,4-c]quinoline
Show/Hide
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C22H29N3O
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1
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| 1 |
Ki > 1000 nM
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CP0652596
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1-Isopropyl-N-[[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl]-1H-indazole-3-carboxamide hydrochloride
Show/Hide
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C20H32ClN5O3S
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1
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| 1 |
Ki > 1000 nM
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CP0690769
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1-Isopropyl-N-[[1-[2-morpholin-4-ylethyl]-4-piperidinyl]methyl]-1H-indazole-3-carboxamide dihydrochloride
Show/Hide
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C23H37Cl2N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0716507
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N-[[1-[3-(Dimethylamino)propyl]-4-piperidinyl]methyl]-1-isopropyl-1H-indazole-3-carboxamide maleate
Show/Hide
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C26H39N5O5
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1
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| 1 |
Ki > 1000 nM
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CP0852268
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N-[[1-(2-Cyclohexylethyl)-4-piperidinyl]methyl]-1-isopropyl-1Hindazole-3-carboxamide hydrochloride
Show/Hide
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C25H39ClN4O
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1
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| 1 |
Ki > 1000 nM
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CP0924842
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1-Isopropyl-N-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-indazole-3-carboxamide hydrochloride
Show/Hide
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C24H31ClN4O
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1
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| 1 |
Ki > 1000 nM
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CP0386711
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8-acetyl-4-methyl-7-[4-(4-pyridin-4-ylpiperazin-1-yl)butoxy]chromen-2-one
Show/Hide
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C25H29N3O4
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1
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| 1 |
Ki > 5000 nM
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CP0520930
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8-acetyl-4-methyl-7-[3-(4-pyrazin-2-ylpiperazin-1-yl)propoxy]chromen-2-one
Show/Hide
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C23H26N4O4
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1
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| 1 |
Ki > 5000 nM
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CP0864706
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4,7-dimethyl-5-(4-(4-(pyridin-4-yl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
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C24H29N3O3
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1
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| 1 |
Ki > 5000 nM
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CP0891123
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4,7-dimethyl-5-(3-(4-(pyridin-4-yl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
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C23H27N3O3
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1
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| 1 |
Ki > 5000 nM
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CP0430131
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4-acetyl-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
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C28H34N4O8S
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1
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| 1 |
Ki < 10000 nM
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CP0432240
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4-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzene-1,4-disulfonamide
Show/Hide
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C26H33N5O9S2
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1
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| 1 |
Ki < 10000 nM
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CP0445660
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2-chloro-N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]benzenesulfonamide
Show/Hide
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C26H31ClN4O7S
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1
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| 1 |
Ki < 10000 nM
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CP0498411
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N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]-4-fluorobenzenesulfonamide
Show/Hide
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C26H31FN4O7S
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1
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| 1 |
Ki < 10000 nM
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CP0502718
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N-[4-[[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)pentanoyl]-2,4-dimethoxyphenyl]sulfamoyl]phenyl]acetamide
Show/Hide
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C28H35N5O8S
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1
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| 1 |
Ki < 10000 nM
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CP0497328
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8-[5-(2-methoxyphenyl)-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C19H25N3O4
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1
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| 1 |
Ki < 10000 nM
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