Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CHEBI:51137
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 PubChem ID
CID: 4184
SID: 14848151
Canonical SMILES
CN1CCN2C(C1)c1ccccc1Cc1ccccc21
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Compound Formula C18H20N2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28223
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
Ki = 1.2 nM
   TI
   LI
   LO
   TS
2
Ki = 2 nM
   TI
   LI
   LO
   TS
3
Ki = 2.2 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 2.8 nM
   TI
   LI
   LO
   TS
2
Ki = 3.2 nM
   TI
   LI
   LO
   TS
CL000309 NCTC clone 929
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 10.47 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20.89 nM
2 Ki = 4.3 nM