Brief Information of the Compound and Protein
| Compound Name |
(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
5-hydroxytryptamine receptor 2A
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Protein Classification |
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
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| Uniprot ID | Gene Name | HTR2A |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | IC50 = 4.67 nM | ||
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| 2 | Ki = 0.15 nM | ||
| 3 | Ki = 0.16 nM | ||
| 4 | Ki = 0.17 nM | ||
| 5 | Ki = 0.19 nM | ||
| 6 | Ki = 0.29 nM | ||
| 7 | Ki = 0.39 nM | ||
| 8 | Ki = 0.5 nM | ||
| 9 | Ki = 0.5012 nM | ||
| 10 | Ki = 0.81 nM | ||
| 11 | Ki < 1 nM | ||