Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[3-(dimethylamino)cyclopentyl]-1-[(4-fluorophenyl)methyl]-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
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 PubChem ID
CID: 168286241
Canonical SMILES
CC(C)COc1ccc(CNC(=O)N(Cc2ccc(F)cc2)C2CCC(C2)N(C)C)cc1
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Compound Formula C26H36FN3O2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28223
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 110.2 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 101 nM
   TI
   LI
   LO
   TS