| Compound ID |
Compound Name |
Compound Formula |
|
CP0342612
|
UNC10107969
Show/Hide
|
C27H35N3O3
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0442857
|
UNC10107968
Show/Hide
|
C26H36N4O3
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0392345
|
7-[4-[4-(2-fluorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H28FN3O2
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0531455
|
UNC10108018
Show/Hide
|
C24H30N4O4
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0436262
|
7-[4-(4-phenylpiperazin-1-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H29N3O2
|
1
|
| 1 |
EC50 = 0.8 nM
|
|
|
|
CP0042927
|
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C23H27Cl2N3O2
|
4
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
EC50 = 130 nM
|
|
|
| 3 |
EC50 = 740 nM
|
|
|
| 4 |
EC50 = 1100 nM
|
|
|
|
CP0518814
|
UNC10108010
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|
C25H30N4O4
|
1
|
| 1 |
EC50 = 1.8 nM
|
|
|
|
CP0006107
|
CAS_85760-74-3
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|
C13H21N3
|
5
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
EC50 = 16 nM
|
|
|
| 3 |
EC50 = 28.18 nM
|
|
|
| 4 |
EC50 = 52 nM
|
|
|
| 5 |
EC50 = 270 nM
|
|
|
|
CP0453632
|
7-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H31N3O3
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0409653
|
(R)-5-Dipropylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one
Show/Hide
|
C16H23N3O
|
1
|
| 1 |
EC50 = 2.53 nM
|
|
|
|
CP0930982
|
Rac-7-(3-(((2-(5-Chloro-2-methoxyphenyl)cyclopropyl)methyl)amino)propoxy)quinolin-2(1H)-one
Show/Hide
|
C23H25ClN2O3
|
1
|
| 1 |
EC50 = 2.63 nM
|
|
|
|
CP0015273
|
N-[4-[2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]ethyl]phenyl]pent-4-ynamide
Show/Hide
|
C26H32N2O2
|
3
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
Ki = 17 nM
|
|
|
| 3 |
Ki = 19 nM
|
|
|
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CP0343133
|
(S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C19H25NOS
|
3
|
| 1 |
EC50 = 3.2 nM
|
|
|
| 2 |
EC50 = 4.1 nM
|
|
|
| 3 |
EC50 = 4.4 nM
|
|
|
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CP0011589
|
N-[4-[2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]ethyl]phenyl]-3-[1-[8-[methyl-[5-[[2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetyl]amino]pentyl]amino]octyl]triazol-4-yl]propanamide
Show/Hide
|
C53H71N9O4S
|
3
|
| 1 |
EC50 = 3.3 nM
|
|
|
| 2 |
Ki = 13 nM
|
|
|
| 3 |
Ki = 50 nM
|
|
|
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CP0453634
|
2-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]piperazin-1-yl]benzonitrile
Show/Hide
|
C24H28N4O2
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0036921
|
3-HYDROXYTYRAMINE HYDROCHLORIDE
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|
C8H11NO2
|
4
|
| 1 |
EC50 = 5 nM
|
|
|
| 2 |
EC50 = 160 nM
|
|
|
| 3 |
EC50 = 200 nM
|
|
|
| 4 |
EC50 = 390 nM
|
|
|
|
CP0013424
|
N-[4-[2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]ethyl]phenyl]-3-[1-[10-[methyl-[5-[[2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetyl]amino]pentyl]amino]decyl]triazol-4-yl]propanamide
Show/Hide
|
C55H75N9O4S
|
3
|
| 1 |
EC50 = 5.5 nM
|
|
|
| 2 |
Ki = 79 nM
|
|
|
| 3 |
Ki = 171 nM
|
|
|
|
CP0283545
|
7-[3-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]propoxy]-3,4-dihydro-2H-isoquinolin-1-one
Show/Hide
|
C23H27Cl2N3O2
|
1
|
| 1 |
EC50 = 5.6 nM
|
|
|
|
CP0187462
|
6-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-1H-indazole
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|
C21H24Cl2N4O
|
1
|
| 1 |
EC50 = 5.7 nM
|
|
|
|
CP0392317
|
7-[4-[[4-(2,3-dichlorophenyl)piperazin-1-yl]methyl]phenoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H25Cl2N3O2
|
1
|
| 1 |
EC50 = 5.7 nM
|
|
|
|
CP0346568
|
UNC10000003
Show/Hide
|
C23H27Cl2N3O2
|
1
|
| 1 |
EC50 = 6.1 nM
|
|
|
|
CP0127400
|
(-)-Pramipexole
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|
C10H17N3S
|
7
|
| 1 |
EC50 = 6.457 nM
|
|
|
| 2 |
EC50 = 9.6 nM
|
|
|
| 3 |
EC50 = 27 nM
|
|
|
| 4 |
EC50 = 100 nM
|
|
|
| 5 |
Kd = 0.0149 nM
|
|
|
| 6 |
Ki = 25.7 nM
|
|
|
| 7 |
Ki = 1000 nM
|
|
|
|
CP0012430
|
N-[4-[2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propylamino]ethyl]phenyl]-3-[1-[6-[[2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetyl]amino]hexyl]triazol-4-yl]propanamide
Show/Hide
|
C45H54N8O4S
|
3
|
| 1 |
EC50 = 7.6 nM
|
|
|
| 2 |
Ki = 142 nM
|
|
|
| 3 |
Ki = 295 nM
|
|
|
|
CP0436260
|
7-[4-[4-(2-ethoxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
EC50 = 7.9 nM
|
|
|
|
CP0488175
|
7-[4-[4-(2-chlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H28ClN3O2
|
1
|
| 1 |
EC50 = 7.9 nM
|
|
|
|
CP0320773
|
6-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy]-1H-indazole
Show/Hide
|
C20H22Cl2N4O
|
1
|
| 1 |
EC50 = 9.7 nM
|
|
|
|
CP0443660
|
5-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy]-1,3-benzothiazole
Show/Hide
|
C20H21Cl2N3OS
|
1
|
| 1 |
EC50 = 9.8 nM
|
|
|
|
CP0418630
|
7-[3-[[2-(2-methoxyphenyl)cyclopropyl]methylamino]propoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0402522
|
UNC10107957
Show/Hide
|
C23H30N4O3
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0097331
|
UNC10107966
Show/Hide
|
C23H25Cl2N3O2
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0292499
|
7-[4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
Show/Hide
|
C23H28Cl2N4O2
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0405813
|
4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-(3-formylpyrazolo[1,5-a]pyridin-5-yl)butanamide
Show/Hide
|
C22H23Cl2N5O2
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0445308
|
7-[4-[4-(2-methylphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0084819
|
(R)-5-Propylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one
Show/Hide
|
C13H17N3O
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0078329
|
5-[4-[4-(2,3-dichlorophenyl)piperidin-1-yl]butoxy]-1,3-benzothiazole
Show/Hide
|
C22H24Cl2N2OS
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0240206
|
N-[4-[methyl-[(10R)-2-oxo-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-10-yl]amino]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C24H27N5O2
|
1
|
| 1 |
EC50 = 22.7 nM
|
|
|
|
CP0436263
|
7-[4-[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0514063
|
7-[4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H28F3N3O2
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0870119
|
7-(4-(((2-(2-Methoxyphenyl)cyclopropyl)methyl)amino)butoxy)-quinolin-2(1H)-one
Show/Hide
|
C24H28N2O3
|
1
|
| 1 |
EC50 = 26.3 nM
|
|
|
|
CP0882687
|
7-(4-(((2-(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)cycloprop-1-yl)-methyl)amino)butoxy)quinolin-2(1H)-one
Show/Hide
|
C25H28N2O4
|
1
|
| 1 |
EC50 = 26.3 nM
|
|
|
|
CP0324453
|
UNC10107962
Show/Hide
|
C26H33N3O3
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0409654
|
(10R)-10-[methyl(propyl)amino]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C14H19N3O
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0078778
|
4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one
Show/Hide
|
C16H24N2O
|
3
|
| 1 |
EC50 = 30 nM
|
|
|
| 2 |
EC50 = 89 nM
|
|
|
| 3 |
EC50 = 330 nM
|
|
|
|
CP0398936
|
(10R)-3-butyl-10-(methylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C15H21N3O
|
1
|
| 1 |
EC50 = 30.5 nM
|
|
|
|
CP0393847
|
(10R)-10-(dipropylamino)-3-propyl-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C19H29N3O
|
1
|
| 1 |
EC50 = 33.9 nM
|
|
|
|
CP0398934
|
(10R)-10-(methylamino)-3-propyl-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C14H19N3O
|
1
|
| 1 |
EC50 = 38.7 nM
|
|
|
|
CP0398933
|
N-[4-[methyl-[(10R)-2-oxo-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-10-yl]amino]butyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C24H26N4O3
|
1
|
| 1 |
EC50 = 43.3 nM
|
|
|
|
CP0178363
|
(R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one
Show/Hide
|
C11H13N3O
|
1
|
| 1 |
EC50 = 60.1 nM
|
|
|
|
CP0412946
|
5-hydroxy-8-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C23H27N5O4
|
1
|
| 1 |
EC50 = 62 nM
|
|
|
|
CP0446908
|
8-hydroxy-5-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]-1,4-diazepan-1-yl]-1H-quinolin-2-one
Show/Hide
|
C27H32N4O4
|
3
|
| 1 |
EC50 = 67 nM
|
|
|
| 2 |
EC50 = 190 nM
|
|
|
| 3 |
EC50 = 200 nM
|
|
|
|
CP0401191
|
(10R)-3-propyl-10-(propylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C16H23N3O
|
1
|
| 1 |
EC50 = 68 nM
|
|
|
|
CP0472405
|
5-hydroxy-8-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]-1,4-diazepan-1-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H32N4O5
|
3
|
| 1 |
EC50 = 78 nM
|
|
|
| 2 |
EC50 = 470 nM
|
|
|
| 3 |
EC50 = 630 nM
|
|
|
|
CP0408071
|
N-(3-cyanopyrazolo[1,5-a]pyridin-5-yl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide
Show/Hide
|
C23H26N6O2
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0458293
|
8-hydroxy-5-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)-1,4-diazepan-1-yl]-1H-quinolin-2-one
Show/Hide
|
C25H29N5O3
|
3
|
| 1 |
EC50 = 90 nM
|
|
|
| 2 |
EC50 = 250 nM
|
|
|
| 3 |
EC50 = 370 nM
|
|
|
|
CP0472407
|
5-hydroxy-8-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]piperazin-1-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H30N4O5
|
1
|
| 1 |
EC50 = 92 nM
|
|
|
|
CP0458292
|
8-hydroxy-5-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]piperazin-1-yl]-1H-quinolin-2-one
Show/Hide
|
C26H30N4O4
|
1
|
| 1 |
EC50 = 93 nM
|
|
|
|
CP0566879
|
7-[4-[[2-(2,3-dihydro-1,4-benzodioxin-5-yl)cyclopropyl]methylamino]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H30N2O4
|
1
|
| 1 |
EC50 = 95.5 nM
|
|
|
|
CP0455926
|
N-[4-[methyl-[(10R)-2-oxo-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-10-yl]amino]butyl]-9H-fluorene-2-carboxamide
Show/Hide
|
C29H30N4O2
|
1
|
| 1 |
EC50 = 109 nM
|
|
|
|
CP0078330
|
7-[4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H29Cl2N3O2
|
3
|
| 1 |
EC50 = 126 nM
|
|
|
| 2 |
EC50 = 270 nM
|
|
|
| 3 |
EC50 > 5000 nM
|
|
|
|
CP0393652
|
7-[4-[4-(8-hydroxy-2-oxochromen-5-yl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C27H31N3O5
|
3
|
| 1 |
EC50 = 130 nM
|
|
|
| 2 |
EC50 = 220 nM
|
|
|
| 3 |
EC50 > 5000 nM
|
|
|
|
CP0405821
|
N-(3-formylpyrazolo[1,5-a]pyridin-5-yl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0445310
|
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-1H-quinolin-2-one
Show/Hide
|
C23H25Cl2N3O2
|
1
|
| 1 |
EC50 = 158 nM
|
|
|
|
CP0499478
|
7-[4-[4-(3-ethoxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
EC50 = 158 nM
|
|
|
|
CP0346569
|
UNC10107953
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
EC50 = 163 nM
|
|
|
|
CP0456743
|
7-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0518813
|
UNC10107955
Show/Hide
|
C24H32N4O3
|
1
|
| 1 |
EC50 = 222 nM
|
|
|
|
CP0405814
|
4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-pyrazolo[1,5-a]pyridin-5-ylbutanamide
Show/Hide
|
C21H23Cl2N5O
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0446909
|
8-hydroxy-5-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]-1H-quinolin-2-one
Show/Hide
|
C24H27N5O3
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0453633
|
7-[4-[4-(4-ethoxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
EC50 = 251 nM
|
|
|
|
CP0486943
|
7-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C22H25Cl2N3O2
|
1
|
| 1 |
EC50 = 251 nM
|
|
|
|
CP0516751
|
UNC10107954
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
EC50 = 306 nM
|
|
|
|
CP0444214
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-[(1R)-1-phenylethyl]urea
Show/Hide
|
C17H24N6OS
|
2
|
| 1 |
EC50 = 338.84 nM
|
|
|
| 2 |
Ki = 154.88 nM
|
|
|
|
CP0436261
|
5-[3-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]propoxy]-1,3-benzothiazole
Show/Hide
|
C21H23Cl2N3OS
|
1
|
| 1 |
EC50 = 348 nM
|
|
|
|
CP0436264
|
7-[4-[4-(2,3-dichlorophenyl)piperidin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H28Cl2N2O2
|
1
|
| 1 |
EC50 = 363 nM
|
|
|
|
CP0405812
|
N-[3-[(Z)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
EC50 = 470 nM
|
|
|
|
CP0117340
|
UNC10099988
Show/Hide
|
C20H22Cl2N4O2
|
1
|
| 1 |
EC50 = 512 nM
|
|
|
|
CP0444218
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-[1-(3-fluorophenyl)ethyl]urea
Show/Hide
|
C17H23FN6OS
|
2
|
| 1 |
EC50 = 588.84 nM
|
|
|
| 2 |
Ki = 316.23 nM
|
|
|
|
CP0412994
|
4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-[3-[(Z)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]butanamide
Show/Hide
|
C22H24Cl2N6O2
|
1
|
| 1 |
EC50 = 600 nM
|
|
|
|
CP0405822
|
4-[4-(2-methoxyphenyl)piperazin-1-yl]-N-pyrazolo[1,5-a]pyridin-5-ylbutanamide
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
EC50 = 630 nM
|
|
|
|
CP0458291
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[3-[4-(8-hydroxy-2-oxo-1H-quinolin-5-yl)-1,4-diazepan-1-yl]propyl]-3-methoxybenzamide
Show/Hide
|
C34H45N7O5
|
1
|
| 1 |
EC50 = 680 nM
|
|
|
|
CP0401190
|
(10R)-10-amino-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C10H11N3O
|
1
|
| 1 |
EC50 = 697 nM
|
|
|
|
CP0405820
|
N-(3-cyanopyrazolo[1,5-a]pyridin-5-yl)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butanamide
Show/Hide
|
C22H22Cl2N6O
|
1
|
| 1 |
EC50 = 870 nM
|
|
|
|
CP0188931
|
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-ynoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H23Cl2N3O2
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0423460
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-pentylurea
Show/Hide
|
C14H26N6OS
|
2
|
| 1 |
EC50 = 1047.13 nM
|
|
|
| 2 |
Ki = 446.68 nM
|
|
|
|
CP0444217
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-[1-(furan-2-yl)ethyl]urea
Show/Hide
|
C15H22N6O2S
|
2
|
| 1 |
EC50 = 1071.52 nM
|
|
|
| 2 |
Ki = 1698.24 nM
|
|
|
|
CP0419814
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-[2-methyl-3-(4-methylphenyl)propyl]urea
Show/Hide
|
C20H30N6OS
|
2
|
| 1 |
EC50 = 1096.48 nM
|
|
|
| 2 |
Ki = 501.19 nM
|
|
|
|
CP0419813
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-(2-phenylbutyl)urea
Show/Hide
|
C19H28N6OS
|
2
|
| 1 |
EC50 = 1122.02 nM
|
|
|
| 2 |
Ki = 524.81 nM
|
|
|
|
CP0545099
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-[6-[[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]carbamoylamino]hexyl]urea;2,2,2-trifluoroacetic acid
Show/Hide
|
C28H40F12N14O10S2
|
3
|
| 1 |
EC50 = 1122.02 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki = 954.99 nM
|
|
|
|
CP0546840
|
1-[N'-[3-(2-amino-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-pentylurea;2,2,2-trifluoroacetic acid
Show/Hide
|
C17H26F6N6O5S
|
3
|
| 1 |
EC50 = 1412.54 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki = 3467.37 nM
|
|
|
|
CP0423456
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-[(1R)-1-phenylethyl]thiourea
Show/Hide
|
C17H24N6S2
|
2
|
| 1 |
EC50 = 1513.56 nM
|
|
|
| 2 |
Ki = 1174.9 nM
|
|
|
|
CP0393916
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[4-(8-hydroxy-2-oxo-1H-quinolin-5-yl)-1,4-diazepan-1-yl]butyl]-3-methoxybenzamide
Show/Hide
|
C35H47N7O5
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0531530
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-benzylurea
Show/Hide
|
C16H22N6OS
|
2
|
| 1 |
EC50 = 1659.59 nM
|
|
|
| 2 |
Ki = 602.56 nM
|
|
|
|
CP0423428
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-(3-cyclohexyl-2-methylpropyl)urea
Show/Hide
|
C19H34N6OS
|
2
|
| 1 |
EC50 = 1698.24 nM
|
|
|
| 2 |
Ki = 478.63 nM
|
|
|
|
CP0423431
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-hexylurea
Show/Hide
|
C15H28N6OS
|
2
|
| 1 |
EC50 = 1737.8 nM
|
|
|
| 2 |
Ki = 562.34 nM
|
|
|
|
CP0444219
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-[(1S)-1-phenylethyl]urea
Show/Hide
|
C17H24N6OS
|
2
|
| 1 |
EC50 = 2691.53 nM
|
|
|
| 2 |
Ki = 794.33 nM
|
|
|
|
CP0423459
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-(2-methyl-5-phenylpentyl)urea
Show/Hide
|
C21H32N6OS
|
2
|
| 1 |
EC50 = 2951.21 nM
|
|
|
| 2 |
Ki = 588.84 nM
|
|
|
|
CP0485229
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-(2-cyclohexylpropyl)urea
Show/Hide
|
C18H32N6OS
|
2
|
| 1 |
EC50 = 3235.94 nM
|
|
|
| 2 |
Ki = 263.03 nM
|
|
|
|
CP0545459
|
1-[N'-[3-(2-amino-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-benzylurea;2,2,2-trifluoroacetic acid
Show/Hide
|
C19H22F6N6O5S
|
3
|
| 1 |
EC50 = 3388.44 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki = 4570.88 nM
|
|
|
|
CP0392383
|
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-2H-isoquinolin-1-one
Show/Hide
|
C23H27Cl2N3O2
|
1
|
| 1 |
EC50 = 3700 nM
|
|
|
|
CP0564608
|
1-[N'-[3-(2-amino-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-[2-methyl-3-(4-methylphenyl)propyl]urea;2,2,2-trifluoroacetic acid
Show/Hide
|
C23H30F6N6O5S
|
3
|
| 1 |
EC50 = 4466.84 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki = 489.78 nM
|
|
|
|
CP0423429
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-(2-methyl-4-phenylbutyl)urea
Show/Hide
|
C20H30N6OS
|
2
|
| 1 |
EC50 = 5370.32 nM
|
|
|
| 2 |
Ki = 354.81 nM
|
|
|
|
CP0188914
|
UNC10099984
Show/Hide
|
C24H29Cl2N3O2
|
1
|
| 1 |
EC50 = 9870 nM
|
|
|
|
CP0420826
|
(6aR)-3-bromo-10,11-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Show/Hide
|
C19H20BrNO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0427261
|
(6aS)-3-bromo-10,11-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Show/Hide
|
C19H20BrNO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0427265
|
(6aS)-1-bromo-10,11-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Show/Hide
|
C19H20BrNO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0427267
|
(6aR)-3-ethyl-10,11-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Show/Hide
|
C21H25NO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0435353
|
[(6aR)-11-acetyloxy-6-methyl-9-propan-2-yl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl] acetate
Show/Hide
|
C24H27NO4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0420830
|
(12R)-13-methyl-4,6-dioxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaene
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0424442
|
[(6aR)-11-acetyloxy-9-chloro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl] acetate
Show/Hide
|
C21H20ClNO4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0427266
|
(6aR)-1-bromo-10,11-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Show/Hide
|
C19H20BrNO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0427272
|
[(6aR)-11-acetyloxy-9-bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl] acetate
Show/Hide
|
C21H20BrNO4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0435351
|
(6aR)-10,11-dimethoxy-3,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Show/Hide
|
C20H23NO2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0435360
|
(6aS)-3-ethyl-10,11-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Show/Hide
|
C21H25NO2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0440881
|
[(6aR)-11-acetyloxy-9-(3-methoxyphenyl)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl] acetate
Show/Hide
|
C28H27NO5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0543296
|
1-[(1R)-1-phenylethyl]-3-[N'-[3-(1H-1,2,4-triazol-5-yl)propyl]carbamimidoyl]urea;dihydrochloride
Show/Hide
|
C15H23Cl2N7O
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki > 10000 nM
|
|
|
|
CP0543298
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-[1-(3-fluorophenyl)ethyl]urea;dihydrochloride
Show/Hide
|
C15H22Cl2FN7OS
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki > 10000 nM
|
|
|
|
CP0543300
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-benzylurea;2,2,2-trifluoroacetic acid
Show/Hide
|
C18H21F6N7O5S
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki = 6309.57 nM
|
|
|
|
CP0546841
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-(2-cyclohexylpropyl)urea;2,2,2-trifluoroacetic acid
Show/Hide
|
C20H31F6N7O5S
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki = 1621.81 nM
|
|
|
|
CP0546844
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-hexylurea;2,2,2-trifluoroacetic acid
Show/Hide
|
C17H27F6N7O5S
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki > 10000 nM
|
|
|
|
CP0550064
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-[(1R)-1-phenylethyl]urea;dihydrochloride
Show/Hide
|
C15H23Cl2N7OS
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki > 10000 nM
|
|
|
|
CP0551746
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-pentylurea;2,2,2-trifluoroacetic acid
Show/Hide
|
C16H25F6N7O5S
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.0149 nM
|
|
|
| 3 |
Ki = 9549.93 nM
|
|
|
|
CP0516189
|
UNC10000007
Show/Hide
|
C27H33Cl2N3O2
|
1
|
| 1 |
EC50 = 46000 nM
|
|
|
|
CP0390315
|
(R)-Modafinil
Show/Hide
|
C15H15NO2S
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0451508
|
N-[2-[bis(4-fluorophenyl)methylsulfanyl]ethyl]-3-phenylpropan-1-amine
Show/Hide
|
C24H25F2NS
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0053105
|
(S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide
Show/Hide
|
C17H25ClN2O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0139957
|
3-[Bis-(4-fluoro-phenyl)-methoxy]-8-butyl-8-aza-bicyclo[3.2.1]octane
Show/Hide
|
C24H29F2NO
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385310
|
US10913711, Compound 10j
Show/Hide
|
C28H32F2N2O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0451512
|
1-[4-[2-[bis(4-fluorophenyl)methylsulfanyl]ethyl]piperazin-1-yl]propan-2-ol
Show/Hide
|
C22H28F2N2OS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0464096
|
US10913711, Compound 10d
Show/Hide
|
C22H28F2N2O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0545461
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-(2-methyl-5-phenylpentyl)urea;2,2,2-trifluoroacetic acid
Show/Hide
|
C23H31F6N7O5S
|
2
|
| 1 |
Kd = 0.0149 nM
|
|
|
| 2 |
Ki = 446.68 nM
|
|
|
|
CP0546843
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-[2-methyl-3-(4-methylphenyl)propyl]urea;2,2,2-trifluoroacetic acid
Show/Hide
|
C22H29F6N7O5S
|
2
|
| 1 |
Kd = 0.0149 nM
|
|
|
| 2 |
Ki = 1071.52 nM
|
|
|
|
CP0008601
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
Show/Hide
|
C21H23ClFNO2
|
1
|
| 1 |
Ki = 0.263 nM
|
|
|
|
CP0415831
|
(1S)-5-methoxy-14-(2-methylpropyl)-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
Show/Hide
|
C20H25NO2S
|
1
|
| 1 |
Ki = 7.54 nM
|
|
|
|
CP0401676
|
(1S)-14-(cyclopropylmethyl)-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
Show/Hide
|
C20H23NO2S
|
1
|
| 1 |
Ki = 11.51 nM
|
|
|
|
CP0382576
|
(1S)-14-(4-chlorobutyl)-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
Show/Hide
|
C20H24ClNO2S
|
1
|
| 1 |
Ki = 12.02 nM
|
|
|
|
CP0399529
|
(1S)-14-(2-chloropropyl)-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
Show/Hide
|
C19H22ClNO2S
|
1
|
| 1 |
Ki = 16.49 nM
|
|
|
|
CP0382575
|
(1S)-14-butyl-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
Show/Hide
|
C20H25NO2S
|
1
|
| 1 |
Ki = 17.61 nM
|
|
|
|
CP0470906
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(13aS)-3-methoxy-9-(2-methoxyethoxy)-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol
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C21H25NO5
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1
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| 1 |
Ki = 18 nM
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CP0411232
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(1S)-14-(3-chloropropyl)-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
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C19H22ClNO2S
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1
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| 1 |
Ki = 18.38 nM
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CP0432162
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(13aS)-3-methoxy-9-pentoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol
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C23H29NO4
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1
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| 1 |
Ki = 23 nM
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CP0475971
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(1S)-5-methoxy-14-(2-methylbutyl)-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
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C21H27NO2S
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1
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| 1 |
Ki = 29.1 nM
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CP0411225
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(1S)-14-(cyclobutylmethyl)-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
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C21H25NO2S
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1
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| 1 |
Ki = 34.23 nM
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CP0382574
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(1S)-14-(2-chloroethyl)-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
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C18H20ClNO2S
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1
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| 1 |
Ki = 34.36 nM
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CP0480718
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(1S)-5-methoxy-14-propyl-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
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C19H23NO2S
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1
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| 1 |
Ki = 38.63 nM
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CP0480362
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(1S)-14-ethyl-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
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C18H21NO2S
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1
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| 1 |
Ki = 40.83 nM
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CP0376923
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(13aS)-3-methoxy-9-propoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol
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C21H25NO4
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1
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| 1 |
Ki = 41 nM
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CP0001862
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N-[5-[8-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]octyl-methylamino]pentyl]-2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetamide
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C49H65N9O5S
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2
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| 1 |
Ki = 45 nM
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| 2 |
Ki = 132 nM
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CP0474189
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(1S)-5-methoxy-14-pentyl-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
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C21H27NO2S
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1
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| 1 |
Ki = 46.7 nM
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CP0006133
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1-(2-methoxyphenyl)-4-[(3-methoxy-4-prop-2-ynoxyphenyl)methyl]piperazine
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C22H26N2O3
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2
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| 1 |
Ki = 69 nM
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| 2 |
Ki = 77 nM
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CP0377065
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(13aS)-12-bromo-3-methoxy-9-propoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol
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C21H24BrNO4
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1
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| 1 |
Ki = 70 nM
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CP0401687
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(1S)-5-methoxy-14-(3-methylbutyl)-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
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C21H27NO2S
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1
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| 1 |
Ki = 79.54 nM
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CP0399530
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(1S)-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
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C16H17NO2S
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1
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| 1 |
Ki = 88.02 nM
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CP0007431
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N-[5-[8-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]octyl-methylamino]pentyl]-2-[3-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]phenoxy]acetamide
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C50H66N8O5S
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2
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| 1 |
Ki = 94 nM
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| 2 |
Ki = 147 nM
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CP0376925
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(13aS)-9-butan-2-yloxy-3-methoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol
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C22H27NO4
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1
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| 1 |
Ki = 104 nM
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CP0089986
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STEPHOLIDINE
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C19H21NO4
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2
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| 1 |
Ki = 105.41 nM
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| 2 |
Ki = 974 nM
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CP0470908
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(13aS)-12-bromo-9-butoxy-3-methoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol
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C22H26BrNO4
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1
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| 1 |
Ki = 107 nM
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CP0006108
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N-[5-[10-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]decyl-methylamino]pentyl]-2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetamide
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C51H69N9O5S
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2
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| 1 |
Ki = 115 nM
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| 2 |
Ki = 303 nM
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CP0443216
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(1S)-16-methoxy-5-oxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-17-ol
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C20H21NO3
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1
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| 1 |
Ki = 146.9 nM
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CP0419584
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(13aS)-3-methoxy-9,11-dimethyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
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C20H23NO2
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1
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| 1 |
Ki = 160.9 nM
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CP0012892
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N-[2-[2-[2-[2-[2-[2-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetamide
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C47H60N8O10S
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2
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| 1 |
Ki = 186 nM
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| 2 |
Ki = 352 nM
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CP0401675
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(1S)-14-(2,2-dimethylpropyl)-5-methoxy-15-thia-10-azatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-4-ol
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C21H27NO2S
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1
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| 1 |
Ki = 189.99 nM
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CP0014446
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N-[2-[2-[2-[2-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]-2-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-3-yl]oxyacetamide
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C43H52N8O8S
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2
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| 1 |
Ki = 251 nM
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| 2 |
Ki = 438 nM
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CP0007147
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N-[5-[10-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]decyl-methylamino]pentyl]-2-[3-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]phenoxy]acetamide
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C52H70N8O5S
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2
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| 1 |
Ki = 252 nM
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| 2 |
Ki = 398 nM
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CP0376922
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(13aS)-12-bromo-9-butan-2-yloxy-3-methoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol
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C22H26BrNO4
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1
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| 1 |
Ki = 331 nM
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CP0376921
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(13aS)-12-bromo-3-methoxy-9-pentoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol
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C23H28BrNO4
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1
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| 1 |
Ki = 398 nM
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CP0444220
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1-[N'-(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)carbamimidoyl]-3-benzylurea
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C16H20N6OS
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1
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| 1 |
Ki = 549.54 nM
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CP0492120
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(13aS)-12-bromo-9-hexoxy-3-methoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,10-diol
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C24H30BrNO4
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1
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| 1 |
Ki = 731 nM
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CP0444221
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(r)-pramipexole
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C10H17N3S
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1
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| 1 |
Ki = 1000 nM
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CP0423463
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1-[N'-(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)carbamimidoyl]-3-hexylurea
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C15H26N6OS
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1
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| 1 |
Ki = 1258.93 nM
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CP0423739
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1-[N'-[3-(2-amino-1,3-thiazol-4-yl)phenyl]carbamimidoyl]-3-hexylurea
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C17H24N6OS
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1
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| 1 |
Ki = 2511.89 nM
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CP0117807
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4-[4-[1-[4-[1-(6-aminohexyl)triazol-4-yl]butyl]piperidin-4-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
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C41H46F3N5O2
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1
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| 1 |
Ki = 8210 nM
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