Brief Information of the Compound and Protein
Compound Name
1-[N'-[3-(2-amino-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-[2-methyl-3-(4-methylphenyl)propyl]urea;2,2,2-trifluoroacetic acid
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PubChem ID
CID: 168292953
Canonical SMILES
OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC(CNC(=O)\N=C(/N)NCCCc1cnc(N)s1)Cc1ccc(C)cc1
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Compound Formula C23H30F6N6O5S
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  3
1
EC50 = 4466.84 nM
   TI
   LI
   LO
   TS
2
Kd = 0.0149 nM
   TI
   LI
   LO
   TS
3
Ki = 489.78 nM
   TI
   LI
   LO
   TS