Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(10R)-10-(dipropylamino)-3-propyl-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
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 PubChem ID
CID: 127047229
Canonical SMILES
CCCN(CCC)[C@@H]1Cc2cccc3n(CCC)c(=O)n(C1)c23
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Compound Formula C19H29N3O
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000153 CHOP
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 13.7 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 33.9 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  9
1
EC50 = 0.9 nM
   TI
   LI
   LO
   TS
2
EC50 = 1 nM
   TI
   LI
   LO
   TS
3
EC50 = 16.8 nM
   TI
   LI
   LO
   TS
4
EC50 = 20.5 nM
   TI
   LI
   LO
   TS
5
IC50 = 98.9 nM
   TI
   LI
   LO
   TS
6
IC50 = 157.8 nM
   TI
   LI
   LO
   TS
7
IC50 = 931.1 nM
   TI
   LI
   LO
   TS
8
Ki = 2.59 nM
   TI
   LI
   LO
   TS
9
Ki = 146 nM
   TI
   LI
   LO
   TS