Brief Information of the Compound and Protein
Compound Name
(S)-6-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol
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PubChem ID
CID: 59227
SID: 14752455
Canonical SMILES
CCCN(CCc1cccs1)[C@H]1CCc2c(O)cccc2C1
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Compound Formula C19H25NOS
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.7 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
Ki = 0.06 nM
   TI
   LI
   LO
   TS
2
Ki = 20 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T Homo sapiens (Human)  3
1
EC50 = 3.2 nM
   TI
   LI
   LO
   TS
2
EC50 = 4.1 nM
   TI
   LI
   LO
   TS
3
EC50 = 4.4 nM
   TI
   LI
   LO
   TS