Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-[4-[4-(4-ethoxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
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 PubChem ID
CID: 71460601
Canonical SMILES
CCOc1ccc(cc1)N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1
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Compound Formula C25H33N3O3
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 53 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 251 nM
   TI
   LI
   LO
   TS
CL000883 HTLA
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 50 nM
   TI
   LI
   LO
   TS