Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-[4-[4-(8-hydroxy-2-oxochromen-5-yl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
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 PubChem ID
CID: 137647533
Canonical SMILES
Oc1ccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c2ccc(=O)oc12
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Compound Formula C27H31N3O5
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 37 nM
   TI
   LI
   LO
   TS
2
Ki = 100 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
2
EC50 = 220 nM
   TI
   LI
   LO
   TS
3
EC50 > 5000 nM
   TI
   LI
   LO
   TS