Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-hydroxy-5-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]-1,4-diazepan-1-yl]-1H-quinolin-2-one
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 PubChem ID
CID: 137657427
Canonical SMILES
Oc1ccc(N2CCCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c2ccc(=O)[nH]c12
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Compound Formula C27H32N4O4
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 0.81 nM
   TI
   LI
   LO
   TS
2
Ki = 1.6 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 67 nM
   TI
   LI
   LO
   TS
2
EC50 = 190 nM
   TI
   LI
   LO
   TS
3
EC50 = 200 nM
   TI
   LI
   LO
   TS