All Bioactivity

Brief Information of the Cell Line and Protein

Cell Line ID: CL000013 , Sf9

Cell Line Info

Synonyms	SF9 sf9 SF-9 Sf-9 sf-9 Sf 9 Spodoptera frugiperda clone 9 Sf clone 9 IPLB-Sf-9AE IPLB-SF-9AE IPLB-SF-9 IPLB-Sf-9 IPLB-Sf9
Category	Spontaneously immortalized cell line
Organism	Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID	CVCL_0549

Protein ID: PT01221 , TGF-beta receptor type-1

Protein Info

Gene Name	TGFBR1
Organism	Homo sapiens, Human
Protein Classification	Kinase
Uniprot ID	P36897

Table of Molecular Bioactivities Related to the Cell Line and Protein

Cell Line ID: CL000013

Cell Line Info

Protein ID: PT01221

Protein Info

Compound ID	Compound Name	Compound Formula
CP0408745 Compound Info	N-(3-fluoropyridin-4-yl)-2-(6-(trifluoromethyl)pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Show/Hide	C17H10F4N6	2
1	IC50 = 0.55 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.22 nM Bioactivity Info	TI LI LO TS
CP0476350 Compound Info	N-(4-methoxyphenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C23H19N7OS	1
1	IC50 = 0.57 nM Bioactivity Info	TI LI LO TS
CP0568900 Compound Info	3-fluoro-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]pyridin-4-amine Show/Hide	C17H13FN6	1
1	IC50 = 0.96 nM Bioactivity Info	TI LI LO TS
CP0114015 Compound Info	N-(4-((2-(6-(trifluoromethyl)pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)pyridin-2-yl)acetamide Show/Hide	C19H14F3N7O	2
1	IC50 = 1 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.15 nM Bioactivity Info	TI LI LO TS
CP0114016 Compound Info	N-[4-[[2-[6-(trifluoromethyl)pyridin-2-yl]-7H-purin-6-yl]amino]pyridin-2-yl]acetamide Show/Hide	C18H13F3N8O	1
1	IC50 = 1.1 nM Bioactivity Info	TI LI LO TS
CP0566963 Compound Info	4-(dimethylamino)-3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile Show/Hide	C25H23N9	1
1	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0169308 Compound Info	N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]pyridin-4-amine Show/Hide	C17H14N6	1
1	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0110711 Compound Info	N-(4-((2-(6-(trifluoromethyl)pyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)amino)pyridin-2-yl)acetamide Show/Hide	C19H14F3N7O	1
1	IC50 = 1.4 nM Bioactivity Info	TI LI LO TS
CP0110716 Compound Info	N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]quinolin-4-amine Show/Hide	C21H16N6	1
1	IC50 = 1.6 nM Bioactivity Info	TI LI LO TS
CP0408746 Compound Info	3-fluoro-N-[2-(pyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]pyridin-4-amine Show/Hide	C16H11FN6	1
1	IC50 = 1.7 nM Bioactivity Info	TI LI LO TS
CP0410274 Compound Info	2-[4-(2-hydroxyethyl)piperazin-1-yl]-N-[4-({2-[6-(trifluoromethyl)pyridin-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)pyridin-2-yl]acetamide Show/Hide	C25H26F3N9O2	1
1	IC50 = 2.1 nM Bioactivity Info	TI LI LO TS
CP0452519 Compound Info	N-(3,4-difluorophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H15F2N7S	1
1	IC50 = 2.12 nM Bioactivity Info	TI LI LO TS
CP0494266 Compound Info	N-(3-methoxyphenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C23H19N7OS	1
1	IC50 = 2.26 nM Bioactivity Info	TI LI LO TS
CP0499159 Compound Info	N-(3-chlorophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H16ClN7S	1
1	IC50 = 2.37 nM Bioactivity Info	TI LI LO TS
CP0410111 Compound Info	2-[(dimethylamino)methyl]-3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile Show/Hide	C26H25N9	1
1	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
CP0527308 Compound Info	N-(3,5-dimethoxyphenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C24H21N7O2S	1
1	IC50 = 2.49 nM Bioactivity Info	TI LI LO TS
CP0237285 Compound Info	N-[2-(pyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]pyridin-4-amine Show/Hide	C16H12N6	1
1	IC50 = 2.5 nM Bioactivity Info	TI LI LO TS
CP0565420 Compound Info	3-(dimethylamino)-5-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile Show/Hide	C25H23N9	1
1	IC50 = 2.6 nM Bioactivity Info	TI LI LO TS
CP0390162 Compound Info	3-(6-methylpyridin-2-yl)-N-phenyl-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H17N7S	1
1	IC50 = 2.82 nM Bioactivity Info	TI LI LO TS
CP0494265 Compound Info	N-(2-chlorophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H16ClN7S	1
1	IC50 = 2.83 nM Bioactivity Info	TI LI LO TS
CP0565418 Compound Info	4-fluoro-1-N,1-N-dimethyl-3-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]benzene-1,3-diamine Show/Hide	C24H23FN8	1
1	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0438292 Compound Info	N-(4-cyanophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C23H16N8S	1
1	IC50 = 2.95 nM Bioactivity Info	TI LI LO TS
CP0511583 Compound Info	3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-[3-(trifluoromethyl)phenyl]pyrazole-1-carbothioamide Show/Hide	C23H16F3N7S	1
1	IC50 = 3.01 nM Bioactivity Info	TI LI LO TS
CP0512838 Compound Info	3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-[4-(trifluoromethyl)phenyl]pyrazole-1-carbothioamide Show/Hide	C23H16F3N7S	1
1	IC50 = 3.04 nM Bioactivity Info	TI LI LO TS
CP0492707 Compound Info	4-[(dimethylamino)methyl]-3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile Show/Hide	C26H25N9	1
1	IC50 = 3.1 nM Bioactivity Info	TI LI LO TS
CP0499157 Compound Info	N-(3,5-difluorophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H15F2N7S	1
1	IC50 = 3.2 nM Bioactivity Info	TI LI LO TS
CP0476351 Compound Info	3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-[4-(trifluoromethoxy)phenyl]pyrazole-1-carbothioamide Show/Hide	C23H16F3N7OS	1
1	IC50 = 3.3 nM Bioactivity Info	TI LI LO TS
CP0566962 Compound Info	3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]-5-(morpholin-4-ylmethyl)benzonitrile Show/Hide	C28H27N9O	1
1	IC50 = 3.3 nM Bioactivity Info	TI LI LO TS
CP0475804 Compound Info	3,5-difluoro-N-[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]pyridin-4-amine Show/Hide	C17H12F2N6	1
1	IC50 = 3.4 nM Bioactivity Info	TI LI LO TS
CP0390161 Compound Info	3-[[3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioyl]amino]benzamide Show/Hide	C23H18N8OS	1
1	IC50 = 3.45 nM Bioactivity Info	TI LI LO TS
CP0512856 Compound Info	N-(3,4-dimethylphenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C24H21N7S	1
1	IC50 = 3.54 nM Bioactivity Info	TI LI LO TS
CP0091953 Compound Info	4-[2-({4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinolin-7-yl}oxy)ethyl]morpholine Show/Hide	C26H27N5O2	2
1	IC50 = 3.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 69 nM Bioactivity Info	TI LI LO TS
CP0396870 Compound Info	N-(3,4-dichlorophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H15Cl2N7S	1
1	IC50 = 3.78 nM Bioactivity Info	TI LI LO TS
CP0507639 Compound Info	N-(4-chlorophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H16ClN7S	1
1	IC50 = 3.87 nM Bioactivity Info	TI LI LO TS
CP0114017 Compound Info	(3S,4S)-4-amino-1-({4-[(3-fluoropyridin-4-yl)amino]-2-(pyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-5-yl}methyl)piperidin-3-ol Show/Hide	C22H23FN8O	1
1	IC50 = 3.9 nM Bioactivity Info	TI LI LO TS
CP0390160 Compound Info	N-(3,5-dimethylphenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C24H21N7S	1
1	IC50 = 3.97 nM Bioactivity Info	TI LI LO TS
CP0505862 Compound Info	N-(3-methylphenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C23H19N7S	1
1	IC50 = 3.98 nM Bioactivity Info	TI LI LO TS
CP0527309 Compound Info	3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-[2-(trifluoromethoxy)phenyl]pyrazole-1-carbothioamide Show/Hide	C23H16F3N7OS	1
1	IC50 = 3.98 nM Bioactivity Info	TI LI LO TS
CP0007000 Compound Info	2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine Show/Hide	C17H13N5	2
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 181 nM Bioactivity Info	TI LI LO TS
CP0499158 Compound Info	N-(2-methylphenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C23H19N7S	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0512480 Compound Info	N-[[4-(1H-indazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H20N6	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0560421 Compound Info	3-fluoro-N-[[4-(1H-indazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H19FN6	1
1	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0508455 Compound Info	N-(4-fluorophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H16FN7S	1
1	IC50 = 4.09 nM Bioactivity Info	TI LI LO TS
CP0010529 Compound Info	GALUNISERTIB Show/Hide	C22H19N5O	5
1	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 51 nM Bioactivity Info	TI LI LO TS
3	IC50 = 69.4 nM Bioactivity Info	TI LI LO TS
4	IC50 = 119 nM Bioactivity Info	TI LI LO TS
5	IC50 = 129 nM Bioactivity Info	TI LI LO TS
CP0512839 Compound Info	N-[3,5-bis(trifluoromethyl)phenyl]-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C24H15F6N7S	1
1	IC50 = 4.12 nM Bioactivity Info	TI LI LO TS
CP0237283 Compound Info	4-N-[[4-[(3-fluoropyridin-4-yl)amino]-2-pyridin-2-ylpyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]cyclohexane-1,4-diamine Show/Hide	C23H25FN8	1
1	IC50 = 4.3 nM Bioactivity Info	TI LI LO TS
CP0129530 Compound Info	US9090625, 4 Show/Hide	C18H16N4S	1
1	IC50 = 4.33 nM Bioactivity Info	TI LI LO TS
CP0484970 Compound Info	N-(3,4-dimethoxyphenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C24H21N7O2S	1
1	IC50 = 4.37 nM Bioactivity Info	TI LI LO TS
CP0475803 Compound Info	(3R,4R)-4-amino-1-({4-[(3-fluoropyridin-4-yl)amino]-2-(pyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-5-yl}methyl)piperidin-3-ol Show/Hide	C22H23FN8O	1
1	IC50 = 4.4 nM Bioactivity Info	TI LI LO TS
CP0484971 Compound Info	N-(3-fluorophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H16FN7S	1
1	IC50 = 4.43 nM Bioactivity Info	TI LI LO TS
CP0454993 Compound Info	N-(3-cyanophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C23H16N8S	1
1	IC50 = 4.5 nM Bioactivity Info	TI LI LO TS
CP0488054 Compound Info	3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]-4-(morpholin-4-ylmethyl)benzonitrile Show/Hide	C28H27N9O	1
1	IC50 = 4.8 nM Bioactivity Info	TI LI LO TS
CP0565421 Compound Info	3-[(dimethylamino)methyl]-5-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile Show/Hide	C26H25N9	1
1	IC50 = 4.9 nM Bioactivity Info	TI LI LO TS
CP0499308 Compound Info	3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile Show/Hide	C23H18N8	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0565422 Compound Info	3-bromo-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18BrN7	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0551631 Compound Info	2-fluoro-N-[[4-(1H-indazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H19FN6	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0560186 Compound Info	N-[[4-(1H-indazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-2-methylaniline Show/Hide	C24H22N6	1
1	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0387691 Compound Info	N-(3,5-dichlorophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H15Cl2N7S	1
1	IC50 = 5.08 nM Bioactivity Info	TI LI LO TS
CP0352413 Compound Info	N-(3-fluoropyridin-4-yl)-2-(6-methylpyridin-2-yl)-7H-purin-6-amine Show/Hide	C16H12FN7	2
1	IC50 = 5.2 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.14 nM Bioactivity Info	TI LI LO TS
CP0454994 Compound Info	N-(2-fluorophenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H16FN7S	1
1	IC50 = 5.39 nM Bioactivity Info	TI LI LO TS
CP0565419 Compound Info	3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]-2-(pyrrolidin-1-ylmethyl)benzonitrile Show/Hide	C28H27N9	1
1	IC50 = 5.6 nM Bioactivity Info	TI LI LO TS
CP0468500 Compound Info	N-(2-methoxyphenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C23H19N7OS	1
1	IC50 = 5.69 nM Bioactivity Info	TI LI LO TS
CP0276945 Compound Info	4-(6-Methyl-pyridin-2-yl)-5-[1,5]naphthyridin-2-yl-thiazol-2-ylamine Show/Hide	C17H13N5S	1
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0396323 Compound Info	3,5-difluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H17F2N7	1
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0473296 Compound Info	3-chloro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18ClN7	1
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0560422 Compound Info	4-fluoro-N-[[4-(1H-indazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H19FN6	1
1	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0505640 Compound Info	N-(4-methylphenyl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C23H19N7S	1
1	IC50 = 6.61 nM Bioactivity Info	TI LI LO TS
CP0519620 Compound Info	US9090625, 7 Show/Hide	C17H14N4S	1
1	IC50 = 6.65 nM Bioactivity Info	TI LI LO TS
CP0410110 Compound Info	2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-3-(morpholin-4-ylmethyl)aniline Show/Hide	C27H27FN8O	1
1	IC50 = 6.8 nM Bioactivity Info	TI LI LO TS
CP0415650 Compound Info	3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]-4-(pyrrolidin-1-ylmethyl)benzonitrile Show/Hide	C28H27N9	1
1	IC50 = 6.8 nM Bioactivity Info	TI LI LO TS
CP0237284 Compound Info	N-{2-[6-(trifluoromethyl)pyridin-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}pyridin-4-amine Show/Hide	C17H11F3N6	1
1	IC50 = 6.8 nM Bioactivity Info	TI LI LO TS
CP0055625 Compound Info	2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18FN7	4
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 9.67 nM Bioactivity Info	TI LI LO TS
3	IC50 = 10 nM Bioactivity Info	TI LI LO TS
4	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0401137 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-3-methylsulfanylaniline Show/Hide	C23H21N7S	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0435379 Compound Info	2-bromo-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18BrN7	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0424302 Compound Info	N-(3-fluoropyridin-4-yl)-2-(6-methylpyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Show/Hide	C17H13FN6	2
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.14 nM Bioactivity Info	TI LI LO TS
CP0416731 Compound Info	N-[(3-fluorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H17FN6S	1
1	IC50 = 7.01 nM Bioactivity Info	TI LI LO TS
CP0521863 Compound Info	N-[(3,4-difluorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H16F2N6S	1
1	IC50 = 7.43 nM Bioactivity Info	TI LI LO TS
CP0431892 Compound Info	3-[[5-(5-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile Show/Hide	C23H17FN8	1
1	IC50 = 7.68 nM Bioactivity Info	TI LI LO TS
CP0326838 Compound Info	US9090625, 12 Show/Hide	C17H14N4S	1
1	IC50 = 7.94 nM Bioactivity Info	TI LI LO TS
CP0465812 Compound Info	3-ethyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H23N7	1
1	IC50 = 8 nM Bioactivity Info	TI LI LO TS
CP0540562 Compound Info	3,4-dichloro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H17Cl2N7	1
1	IC50 = 8 nM Bioactivity Info	TI LI LO TS
CP0421305 Compound Info	N-[[4-(2,1,3-benzothiadiazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-3-fluoroaniline Show/Hide	C22H17FN6S	1
1	IC50 = 8 nM Bioactivity Info	TI LI LO TS
CP0512481 Compound Info	N-[[4-(1H-indazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-3-methylaniline Show/Hide	C24H22N6	1
1	IC50 = 8 nM Bioactivity Info	TI LI LO TS
CP0481000 Compound Info	3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]-2-(morpholin-4-ylmethyl)benzonitrile Show/Hide	C28H27N9O	1
1	IC50 = 8.1 nM Bioactivity Info	TI LI LO TS
CP0424489 Compound Info	N-[(4-fluorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H17FN6S	1
1	IC50 = 8.61 nM Bioactivity Info	TI LI LO TS
CP0386684 Compound Info	N-[(4-methylphenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C23H20N6S	1
1	IC50 = 8.75 nM Bioactivity Info	TI LI LO TS
CP0436559 Compound Info	N-[(3,5-difluorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H16F2N6S	1
1	IC50 = 8.92 nM Bioactivity Info	TI LI LO TS
CP0380977 Compound Info	3-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18FN7	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0435378 Compound Info	2-chloro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18ClN7	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0478057 Compound Info	2,3-difluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H17F2N7	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0478171 Compound Info	3-methyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H21N7	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0480966 Compound Info	3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzamide Show/Hide	C23H20N8O	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0560187 Compound Info	N-[[4-(1H-indazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-4-methylaniline Show/Hide	C24H22N6	1
1	IC50 = 9 nM Bioactivity Info	TI LI LO TS
CP0530926 Compound Info	3-[[5-(3-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile Show/Hide	C23H17FN8	1
1	IC50 = 9.23 nM Bioactivity Info	TI LI LO TS
CP0539687 Compound Info	N-[[5-(5-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18FN7	1
1	IC50 = 9.23 nM Bioactivity Info	TI LI LO TS
CP0427572 Compound Info	3-[[[4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-yl]amino]methyl]benzonitrile Show/Hide	C23H17N7S	1
1	IC50 = 9.26 nM Bioactivity Info	TI LI LO TS
CP0468635 Compound Info	N-[[5-(3-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18FN7	1
1	IC50 = 9.76 nM Bioactivity Info	TI LI LO TS
CP0381365 Compound Info	3-ethenyl-N-[[5-(3-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H20FN7	1
1	IC50 = 9.81 nM Bioactivity Info	TI LI LO TS
CP0017299 Compound Info	4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiazol-2-ylamine Show/Hide	C17H11ClN4S	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0025659 Compound Info	4-(4-Fluoro-phenyl)-5-[1,5]naphthyridin-2-yl-thiazol-2-ylamine Show/Hide	C17H11FN4S	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0276946 Compound Info	2-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine Show/Hide	C16H11N5	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0234054 Compound Info	3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methylamino)benzamide Show/Hide	C25H21N7O	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0476349 Compound Info	3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-[3-(trifluoromethoxy)phenyl]pyrazole-1-carbothioamide Show/Hide	C23H16F3N7OS	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0395448 Compound Info	3,4-difluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H17F2N7	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0490040 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-2-methylsulfanylaniline Show/Hide	C23H21N7S	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0477281 Compound Info	N-[[4-(2,1,3-benzothiadiazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-4-fluoroaniline Show/Hide	C22H17FN6S	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0560193 Compound Info	3-methyl-N-[[4-(1-methylindazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C25H24N6	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0433920 Compound Info	N-[(3-chlorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H17ClN6S	1
1	IC50 = 10.2 nM Bioactivity Info	TI LI LO TS
CP0512433 Compound Info	N-[(2-fluorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H17FN6S	1
1	IC50 = 10.4 nM Bioactivity Info	TI LI LO TS
CP0530925 Compound Info	3-[[5-(5-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzamide Show/Hide	C23H19FN8O	1
1	IC50 = 10.8 nM Bioactivity Info	TI LI LO TS
CP0380976 Compound Info	2-ethyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H23N7	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0465813 Compound Info	2-[3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]phenyl]acetonitrile Show/Hide	C24H20N8	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0465815 Compound Info	4-chloro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18ClN7	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0494722 Compound Info	3-[(dimethylamino)methyl]-2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C25H25FN8	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0474946 Compound Info	3-[[5-(3-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzamide Show/Hide	C23H19FN8O	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0483379 Compound Info	N-[[4-(2,1,3-benzothiadiazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-2-fluoroaniline Show/Hide	C22H17FN6S	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0512482 Compound Info	3-fluoro-N-[[4-(1-methylindazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H21FN6	1
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0439905 Compound Info	N-[(3-methylphenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C23H20N6S	1
1	IC50 = 11.2 nM Bioactivity Info	TI LI LO TS
CP0512434 Compound Info	N-benzyl-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H18N6S	1
1	IC50 = 11.3 nM Bioactivity Info	TI LI LO TS
CP0514735 Compound Info	N-[(3-methoxyphenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C23H20N6OS	1
1	IC50 = 11.4 nM Bioactivity Info	TI LI LO TS
CP0295820 Compound Info	3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methylamino)benzonitrile Show/Hide	C25H19N7	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0514733 Compound Info	3-[[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-yl]amino]methyl]benzamide Show/Hide	C23H19N7OS	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0435380 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-2-(trifluoromethoxy)aniline Show/Hide	C23H18F3N7O	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0526574 Compound Info	3-ethenyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H21N7	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0566781 Compound Info	2,3-dichloro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H17Cl2N7	1
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
CP0380335 Compound Info	2-fluoro-N-[[5-(3-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H17F2N7	1
1	IC50 = 12.1 nM Bioactivity Info	TI LI LO TS
CP0472542 Compound Info	2-fluoro-N-[[5-(5-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H17F2N7	1
1	IC50 = 12.5 nM Bioactivity Info	TI LI LO TS
CP0300059 Compound Info	US9090625, 5 Show/Hide	C19H16N4S	1
1	IC50 = 12.9 nM Bioactivity Info	TI LI LO TS
CP0390057 Compound Info	2-[3-(6-methylpyridin-2-yl)-4-quinoxalin-6-ylpyrazol-1-yl]-N-phenylethanethioamide Show/Hide	C25H20N6S	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0400764 Compound Info	1-[3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]phenyl]ethanone Show/Hide	C24H21N7O	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0469144 Compound Info	6-[5-(6-methylpyridin-2-yl)-2-(phenoxymethyl)-1H-imidazol-4-yl]-[1,2,4]triazolo[1,5-a]pyridine Show/Hide	C22H18N6O	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0527607 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H19N7	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0477282 Compound Info	N-[[4-(2,1,3-benzothiadiazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-3-methylaniline Show/Hide	C23H20N6S	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0560189 Compound Info	2-fluoro-N-[[4-(1-methylindazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H21FN6	1
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0436557 Compound Info	3-[[[4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-yl]amino]methyl]benzamide Show/Hide	C23H19N7OS	1
1	IC50 = 13.6 nM Bioactivity Info	TI LI LO TS
CP0374672 Compound Info	3-ethenyl-N-[[5-(5-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H20FN7	1
1	IC50 = 13.7 nM Bioactivity Info	TI LI LO TS
CP0391705 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-2-propan-2-ylaniline Show/Hide	C25H25N7	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0465811 Compound Info	2-methyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H21N7	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0478169 Compound Info	2-methoxy-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H21N7O	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0540563 Compound Info	3,5-dimethoxy-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H23N7O2	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0567418 Compound Info	3,5-dimethyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H23N7	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0571532 Compound Info	2-ethenyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H21N7	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0573410 Compound Info	3-methoxy-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H21N7O	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0475536 Compound Info	2-methyl-N-[[4-(6-methylpyridin-2-yl)-5-thieno[3,2-c]pyridin-2-yl-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H21N5S	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0576068 Compound Info	N-[[4-(2,1,3-benzothiadiazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18N6S	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0486131 Compound Info	N-[[4-(1-methylindazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H22N6	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0444432 Compound Info	3-((5-(6-ethylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methylamino)benzamide Show/Hide	C26H23N7O	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0403761 Compound Info	N-[3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]phenyl]methanesulfonamide Show/Hide	C23H22N8O2S	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0465814 Compound Info	N-[3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]phenyl]acetamide Show/Hide	C24H22N8O	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0524466 Compound Info	3,5-dichloro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H17Cl2N7	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0566947 Compound Info	N-[2-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]phenyl]methanesulfonamide Show/Hide	C23H22N8O2S	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0512431 Compound Info	N-[(3,5-dichlorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H16Cl2N6S	1
1	IC50 = 15.1 nM Bioactivity Info	TI LI LO TS
CP0440748 Compound Info	5-[(dimethylamino)methyl]-2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C25H25FN8	1
1	IC50 = 15.3 nM Bioactivity Info	TI LI LO TS
CP0512432 Compound Info	N-[(2-chlorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H17ClN6S	1
1	IC50 = 15.5 nM Bioactivity Info	TI LI LO TS
CP0452520 Compound Info	4-[[3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioyl]amino]benzamide Show/Hide	C23H18N8OS	1
1	IC50 = 15.6 nM Bioactivity Info	TI LI LO TS
CP0436170 Compound Info	N-[(4-chlorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H17ClN6S	1
1	IC50 = 15.8 nM Bioactivity Info	TI LI LO TS
CP0510544 Compound Info	5-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-amine Show/Hide	C18H15N5S	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0380978 Compound Info	4-methyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H21N7	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0469355 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-3-propan-2-ylaniline Show/Hide	C25H25N7	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0560191 Compound Info	4-fluoro-N-[[4-(1-methylindazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H21FN6	1
1	IC50 = 16 nM Bioactivity Info	TI LI LO TS
CP0420952 Compound Info	N-[(3,5-dimethoxyphenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C24H22N6O2S	1
1	IC50 = 16.5 nM Bioactivity Info	TI LI LO TS
CP0453776 Compound Info	N-[(2-methylphenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C23H20N6S	1
1	IC50 = 16.9 nM Bioactivity Info	TI LI LO TS
CP0173805 Compound Info	3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methyl)benzamide Show/Hide	C25H20N6O	3
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
2	IC50 = 17.2 nM Bioactivity Info	TI LI LO TS
3	IC50 = 36 nM Bioactivity Info	TI LI LO TS
CP0395449 Compound Info	3,4-dimethyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H23N7	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0435381 Compound Info	4-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18FN7	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0469146 Compound Info	methyl 3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzoate Show/Hide	C24H21N7O2	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0473297 Compound Info	4-bromo-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18BrN7	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0477285 Compound Info	3-fluoro-N-[[4-(6-methylpyridin-2-yl)-5-thieno[3,2-c]pyridin-2-yl-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H18FN5S	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0440749 Compound Info	3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]-5-(pyrrolidin-1-ylmethyl)benzonitrile Show/Hide	C28H27N9	1
1	IC50 = 17.8 nM Bioactivity Info	TI LI LO TS
CP0403754 Compound Info	N-(3-cyanophenyl)-2-[3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazol-1-yl]ethanethioamide Show/Hide	C24H18N8S	1
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0556683 Compound Info	2,3-dimethyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H23N7	1
1	IC50 = 18 nM Bioactivity Info	TI LI LO TS
CP0327400 Compound Info	US9090625, 13 Show/Hide	C19H16N4S	1
1	IC50 = 18.9 nM Bioactivity Info	TI LI LO TS
CP0110712 Compound Info	N-[2-(6-methoxypyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]pyridin-4-amine Show/Hide	C17H14N6O	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0578992 Compound Info	3-methyl-N-[[4-(6-methylpyridin-2-yl)-5-thieno[3,2-c]pyridin-2-yl-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H21N5S	1
1	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0436144 Compound Info	4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-[[3-(trifluoromethoxy)phenyl]methyl]-1,3-thiazol-2-amine Show/Hide	C23H17F3N6OS	1
1	IC50 = 19.3 nM Bioactivity Info	TI LI LO TS
CP0026932 Compound Info	5-(1,5-naphthyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine Show/Hide	C16H11N5S	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0040672 Compound Info	2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazolin-4-amine Show/Hide	C17H13N5S	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0566946 Compound Info	2-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile Show/Hide	C23H18N8	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0444430 Compound Info	3-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzamide Show/Hide	C24H21N5O3	1
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0461565 Compound Info	6-[5-(6-methylpyridin-2-yl)-2-(phenylsulfanylmethyl)-1H-imidazol-4-yl]-[1,2,4]triazolo[1,5-a]pyridine Show/Hide	C22H18N6S	1
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0567417 Compound Info	3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzene-1,2-dicarbonitrile Show/Hide	C24H17N9	1
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0561508 Compound Info	N-[[4-(2,1,3-benzothiadiazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-2-methylaniline Show/Hide	C23H20N6S	1
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0424069 Compound Info	N-[(2-fluorophenyl)methyl]-5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H17FN6S	1
1	IC50 = 21.2 nM Bioactivity Info	TI LI LO TS
CP0514734 Compound Info	N-[(3,4-dichlorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H16Cl2N6S	1
1	IC50 = 21.9 nM Bioactivity Info	TI LI LO TS
CP0198179 Compound Info	1-methyl-6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo-[1,2-b]pyrazol-3-yl]-1H-benzoimidazole Show/Hide	C20H19N5	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0374429 Compound Info	2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinolin-4-amine Show/Hide	C20H16N4	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0497533 Compound Info	2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[3,2-d]pyrimidin-4-amine Show/Hide	C17H13N5S	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0460662 Compound Info	N-(3-cyanophenyl)-2-[3-(6-methylpyridin-2-yl)-4-quinolin-6-ylpyrazol-1-yl]acetamide Show/Hide	C27H20N6O	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0439904 Compound Info	N-[(3,5-dimethylphenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C24H22N6S	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0403746 Compound Info	3-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylcarbamothioyl]benzamide Show/Hide	C24H20N8OS	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0578060 Compound Info	N-[[4-(2,1,3-benzothiadiazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]-4-methylaniline Show/Hide	C23H20N6S	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0416727 Compound Info	N-[(2,3-dimethylphenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C24H22N6S	1
1	IC50 = 22.1 nM Bioactivity Info	TI LI LO TS
CP0480999 Compound Info	2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-3-(pyrrolidin-1-ylmethyl)aniline Show/Hide	C27H27FN8	1
1	IC50 = 22.1 nM Bioactivity Info	TI LI LO TS
CP0461567 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-3-(trifluoromethoxy)aniline Show/Hide	C23H18F3N7O	1
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0490128 Compound Info	2-fluoro-N-[[4-(6-methylpyridin-2-yl)-5-thieno[3,2-c]pyridin-2-yl-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H18FN5S	1
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
CP0137007 Compound Info	US9090625, 1 Show/Hide	C16H12N4S	1
1	IC50 = 23.4 nM Bioactivity Info	TI LI LO TS
CP0037799 Compound Info	Dihydropyrrolopyrazole, 15a Show/Hide	C24H25N5O	1
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
CP0427249 Compound Info	3-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-ylamino)methyl)benzonitrile Show/Hide	C24H19N5O2	1
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
CP0512483 Compound Info	2-methyl-N-[[4-(1-methylindazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C25H24N6	1
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
CP0453777 Compound Info	N-[(4-methoxyphenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C23H20N6OS	1
1	IC50 = 24.3 nM Bioactivity Info	TI LI LO TS
CP0526990 Compound Info	N-benzyl-5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H18N6S	1
1	IC50 = 24.5 nM Bioactivity Info	TI LI LO TS
CP0048685 Compound Info	2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazolin-4-amine Show/Hide	C19H15N5	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0262281 Compound Info	N-(1H-indazol-5-yl)-2-(6-methylpyridin-2-yl)quinazolin-4-amine Show/Hide	C21H16N6	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0372213 Compound Info	3-(3-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1H-pyrazol-1-yl)-N-phenylpropanamide Show/Hide	C27H23N5O	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0465818 Compound Info	2-[4-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]phenyl]acetonitrile Show/Hide	C24H20N8	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0410275 Compound Info	N-[5-fluoro-4-({2-[6-(trifluoromethyl)pyridin-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)pyridin-2-yl]acetamide Show/Hide	C19H13F4N7O	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0475534 Compound Info	N-[[4-(6-methylpyridin-2-yl)-5-thieno[3,2-c]pyridin-2-yl-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H19N5S	1
1	IC50 = 25 nM Bioactivity Info	TI LI LO TS
CP0437640 Compound Info	3-[[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-yl]amino]methyl]benzonitrile Show/Hide	C23H17N7S	1
1	IC50 = 25.1 nM Bioactivity Info	TI LI LO TS
CP0526991 Compound Info	4-[[[4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-yl]amino]methyl]benzamide Show/Hide	C23H19N7OS	1
1	IC50 = 25.7 nM Bioactivity Info	TI LI LO TS
CP0469045 Compound Info	3-((4-(6-Methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-imidazol-2-yl)methyl)benzonitrile Show/Hide	C26H19N5	1
1	IC50 = 26 nM Bioactivity Info	TI LI LO TS
CP0494460 Compound Info	N-(3-cyanophenyl)-2-[3-(6-methylpyridin-2-yl)-4-quinoxalin-6-ylpyrazol-1-yl]ethanethioamide Show/Hide	C26H19N7S	1
1	IC50 = 26 nM Bioactivity Info	TI LI LO TS
CP0391688 Compound Info	2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]benzenecarbothioamide Show/Hide	C23H18FN7S	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0484192 Compound Info	N-(3-cyanophenyl)-2-[3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazol-1-yl]acetamide Show/Hide	C24H18N8O	1
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
CP0391687 Compound Info	N-(2-fluorophenyl)-2-[3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazol-1-yl]ethanethioamide Show/Hide	C23H18FN7S	1
1	IC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0436493 Compound Info	N-[(2,3-difluorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H16F2N6S	1
1	IC50 = 29.4 nM Bioactivity Info	TI LI LO TS
CP0465817 Compound Info	4-ethenyl-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H21N7	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0469354 Compound Info	2-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzamide Show/Hide	C23H20N8O	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0382697 Compound Info	2-[4-(2,1,3-benzothiadiazol-5-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-(3-fluorophenyl)ethanethioamide Show/Hide	C23H17FN6S2	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0438658 Compound Info	2-[4-(2,1,3-benzothiadiazol-5-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-phenylacetamide Show/Hide	C23H18N6OS	1
1	IC50 = 30 nM Bioactivity Info	TI LI LO TS
CP0424068 Compound Info	4-[[[4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-yl]amino]methyl]benzonitrile Show/Hide	C23H17N7S	1
1	IC50 = 30.8 nM Bioactivity Info	TI LI LO TS
CP0556681 Compound Info	4-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile Show/Hide	C23H18N8	1
1	IC50 = 32 nM Bioactivity Info	TI LI LO TS
CP0399710 Compound Info	7-(2-chloroethoxy)-4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C22H19ClN4O	1
1	IC50 = 33 nM Bioactivity Info	TI LI LO TS
CP0166056 Compound Info	3-((4-(6-Methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-imidazol-2-yl)methyl)benzamide Show/Hide	C26H21N5O	1
1	IC50 = 34 nM Bioactivity Info	TI LI LO TS
CP0476537 Compound Info	3-((4-(6-Methylpyridin-2-yl)-3-(quinolin-6-yl)-1H-pyrazol-1-yl)methyl)benzonitrile Show/Hide	C26H19N5	1
1	IC50 = 34 nM Bioactivity Info	TI LI LO TS
CP0512484 Compound Info	4-methyl-N-[[4-(1-methylindazol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C25H24N6	1
1	IC50 = 34 nM Bioactivity Info	TI LI LO TS
CP0446191 Compound Info	N-[(2,3-dichlorophenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C22H16Cl2N6S	1
1	IC50 = 34.3 nM Bioactivity Info	TI LI LO TS
CP0015550 Compound Info	2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine Show/Hide	C20H21N3O2	4
1	IC50 = 34.9 nM Bioactivity Info	TI LI LO TS
2	IC50 = 54 nM Bioactivity Info	TI LI LO TS
3	IC50 = 54.4 nM Bioactivity Info	TI LI LO TS
4	IC50 = 169 nM Bioactivity Info	TI LI LO TS
CP0566315 Compound Info	US9090625, 6 Show/Hide	C18H16N4S	1
1	IC50 = 35.2 nM Bioactivity Info	TI LI LO TS
CP0527742 Compound Info	4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-[[2-(trifluoromethoxy)phenyl]methyl]-1,3-thiazol-2-amine Show/Hide	C23H17F3N6OS	1
1	IC50 = 35.9 nM Bioactivity Info	TI LI LO TS
CP0403745 Compound Info	3-[[2-[3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazol-1-yl]acetyl]amino]benzamide Show/Hide	C24H20N8O2	1
1	IC50 = 36 nM Bioactivity Info	TI LI LO TS
CP0473192 Compound Info	3-cyano-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]benzenecarbothioamide Show/Hide	C24H18N8S	1
1	IC50 = 36 nM Bioactivity Info	TI LI LO TS
CP0380891 Compound Info	2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]benzamide Show/Hide	C23H18FN7O	1
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
CP0512556 Compound Info	2-[3-(6-methylpyridin-2-yl)-4-quinoxalin-6-ylpyrazol-1-yl]-N-phenylacetamide Show/Hide	C25H20N6O	1
1	IC50 = 38 nM Bioactivity Info	TI LI LO TS
CP0435382 Compound Info	N-[4-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]phenyl]acetamide Show/Hide	C24H22N8O	1
1	IC50 = 39 nM Bioactivity Info	TI LI LO TS
CP0402004 Compound Info	2-[3-(6-methylpyridin-2-yl)-4-thieno[3,2-c]pyridin-2-ylpyrazol-1-yl]-N-phenylacetamide Show/Hide	C24H19N5OS	1
1	IC50 = 39 nM Bioactivity Info	TI LI LO TS
CP0390159 Compound Info	N-(1-methylpiperidin-4-yl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C22H24N8S	1
1	IC50 = 39.47 nM Bioactivity Info	TI LI LO TS
CP0167334 Compound Info	2-(6-methylpyridin-2-yl)-N-(pyrimidin-4-yl)quinazolin-4-amine Show/Hide	C18H14N6	1
1	IC50 = 40 nM Bioactivity Info	TI LI LO TS
CP0461566 Compound Info	N-[2-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]phenyl]acetamide Show/Hide	C24H22N8O	1
1	IC50 = 40 nM Bioactivity Info	TI LI LO TS
CP0540618 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-4-methylsulfanylaniline Show/Hide	C23H21N7S	1
1	IC50 = 40 nM Bioactivity Info	TI LI LO TS
CP0140650 Compound Info	3-(6-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-benzo[d]imidazol-1-yl)propan-1-ol Show/Hide	C22H23N5O	1
1	IC50 = 41 nM Bioactivity Info	TI LI LO TS
CP0380334 Compound Info	2-fluoro-N-[[5-(4-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H17F2N7	1
1	IC50 = 41.9 nM Bioactivity Info	TI LI LO TS
CP0437045 Compound Info	4-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methylamino)benzonitrile Show/Hide	C25H19N7	1
1	IC50 = 42 nM Bioactivity Info	TI LI LO TS
CP0520099 Compound Info	2-[4-(2,1,3-benzothiadiazol-5-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-phenylethanethioamide Show/Hide	C23H18N6S2	1
1	IC50 = 42 nM Bioactivity Info	TI LI LO TS
CP0483380 Compound Info	4-fluoro-N-[[4-(6-methylpyridin-2-yl)-5-thieno[3,2-c]pyridin-2-yl-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H18FN5S	1
1	IC50 = 42 nM Bioactivity Info	TI LI LO TS
CP0538133 Compound Info	4-methyl-N-[[4-(6-methylpyridin-2-yl)-5-thieno[3,2-c]pyridin-2-yl-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H21N5S	1
1	IC50 = 43 nM Bioactivity Info	TI LI LO TS
CP0521326 Compound Info	N-(3-fluorophenyl)-2-[3-(6-methylpyridin-2-yl)-4-quinolin-4-ylpyrazol-1-yl]ethanethioamide Show/Hide	C26H20FN5S	1
1	IC50 = 43 nM Bioactivity Info	TI LI LO TS
CP0433235 Compound Info	N-[(2,3-dimethoxyphenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C24H22N6O2S	1
1	IC50 = 43.5 nM Bioactivity Info	TI LI LO TS
CP0443049 Compound Info	3,4-dimethoxy-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H23N7O2	1
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
CP0444431 Compound Info	3-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzonitrile Show/Hide	C24H19N5O2	1
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
CP0444433 Compound Info	3-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-ethylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzamide Show/Hide	C25H23N5O3	1
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
CP0571538 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-4-propan-2-ylaniline Show/Hide	C25H25N7	1
1	IC50 = 46 nM Bioactivity Info	TI LI LO TS
CP0208736 Compound Info	6-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1Hbenzoimidazole Show/Hide	C19H17N5	1
1	IC50 = 47 nM Bioactivity Info	TI LI LO TS
CP0436406 Compound Info	Dihydropyrrolopyrazole, 16a Show/Hide	C27H31N5O	1
1	IC50 = 47 nM Bioactivity Info	TI LI LO TS
CP0357782 Compound Info	4-((5-(6-ethylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methylamino)benzonitrile Show/Hide	C26H21N7	1
1	IC50 = 47 nM Bioactivity Info	TI LI LO TS
CP0556682 Compound Info	N-[4-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]phenyl]methanesulfonamide Show/Hide	C23H22N8O2S	1
1	IC50 = 47 nM Bioactivity Info	TI LI LO TS
CP0507448 Compound Info	N-[(3,4-dimethoxyphenyl)methyl]-4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1,3-thiazol-2-amine Show/Hide	C24H22N6O2S	1
1	IC50 = 47.7 nM Bioactivity Info	TI LI LO TS
CP0513062 Compound Info	3-[[2-[3-(6-methylpyridin-2-yl)-4-quinoxalin-6-ylpyrazol-1-yl]acetyl]amino]benzamide Show/Hide	C26H21N7O2	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0380951 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]benzenecarbothioamide Show/Hide	C23H19N7S	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0566948 Compound Info	4-methoxy-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C23H21N7O	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0516362 Compound Info	1-(4-methylpiperazin-1-yl)-2-({4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinolin-7-yl}oxy)ethan-1-one Show/Hide	C27H28N6O2	1
1	IC50 = 49 nM Bioactivity Info	TI LI LO TS
CP0308587 Compound Info	2-(3-chlorophenyl)-N-(pyridin-4-yl)quinazolin-4-amine Show/Hide	C19H13ClN4	1
1	IC50 = 49 nM Bioactivity Info	TI LI LO TS
CP0015520 Compound Info	4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline Show/Hide	C17H12N4	2
1	IC50 = 51 nM Bioactivity Info	TI LI LO TS
2	IC50 = 59 nM Bioactivity Info	TI LI LO TS
CP0372214 Compound Info	N-(3-cyanophenyl)-2-[3-(6-methylpyridin-2-yl)-4-quinolin-6-ylpyrazol-1-yl]ethanethioamide Show/Hide	C27H20N6S	1
1	IC50 = 51 nM Bioactivity Info	TI LI LO TS
CP0415895 Compound Info	N-(2-fluorophenyl)-2-[3-(6-methylpyridin-2-yl)-4-quinolin-4-ylpyrazol-1-yl]ethanethioamide Show/Hide	C26H20FN5S	1
1	IC50 = 53 nM Bioactivity Info	TI LI LO TS
CP0904505 Compound Info	2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine hydrochloride Show/Hide	C20H22ClN3O2	2
1	IC50 = 54 nM Bioactivity Info	TI LI LO TS
2	IC50 = 54.4 nM Bioactivity Info	TI LI LO TS
CP0480451 Compound Info	4-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzamide Show/Hide	C23H20N8O	1
1	IC50 = 55 nM Bioactivity Info	TI LI LO TS
CP0438615 Compound Info	2-[4-(2,1,3-benzothiadiazol-5-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-(2-fluorophenyl)ethanethioamide Show/Hide	C23H17FN6S2	1
1	IC50 = 55 nM Bioactivity Info	TI LI LO TS
CP0458538 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]benzamide Show/Hide	C23H19N7O	1
1	IC50 = 57 nM Bioactivity Info	TI LI LO TS
CP0530779 Compound Info	2-[3-(6-methylpyridin-2-yl)-4-quinolin-4-ylpyrazol-1-yl]-N-phenylethanethioamide Show/Hide	C26H21N5S	1
1	IC50 = 57 nM Bioactivity Info	TI LI LO TS
CP0527770 Compound Info	2,3-dimethoxy-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C24H23N7O2	1
1	IC50 = 58 nM Bioactivity Info	TI LI LO TS
CP0469147 Compound Info	1-[4-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]phenyl]ethanone Show/Hide	C24H21N7O	1
1	IC50 = 59 nM Bioactivity Info	TI LI LO TS
CP0465816 Compound Info	N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]-4-(trifluoromethoxy)aniline Show/Hide	C23H18F3N7O	1
1	IC50 = 60 nM Bioactivity Info	TI LI LO TS
CP0436173 Compound Info	4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1,3-thiazol-2-amine Show/Hide	C23H17F3N6OS	1
1	IC50 = 60.9 nM Bioactivity Info	TI LI LO TS
CP0439000 Compound Info	3-((4-(6-Methylpyridin-2-yl)-3-(quinolin-6-yl)-1H-pyrazol-1-yl)methyl)benzamide Show/Hide	C26H21N5O	1
1	IC50 = 61 nM Bioactivity Info	TI LI LO TS
CP0568899 Compound Info	4-{[2-(6-methylpyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino}-N-(propan-2-yl)pyridine-3-carboxamide Show/Hide	C21H21N7O	1
1	IC50 = 62 nM Bioactivity Info	TI LI LO TS
CP0476353 Compound Info	3-[[3-(6-methylpyridin-2-yl)-4-(2-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioyl]amino]benzamide Show/Hide	C24H20N8OS	1
1	IC50 = 66.8 nM Bioactivity Info	TI LI LO TS
CP0299325 Compound Info	4-(3-(6-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-benzo[d]imidazol-1-yl)propyl)morpholine Show/Hide	C26H30N6O	1
1	IC50 = 69 nM Bioactivity Info	TI LI LO TS
CP0367222 Compound Info	N-(3-cyanophenyl)-2-[3-(6-methylpyridin-2-yl)-4-quinolin-4-ylpyrazol-1-yl]ethanethioamide Show/Hide	C27H20N6S	1
1	IC50 = 69 nM Bioactivity Info	TI LI LO TS
CP0394259 Compound Info	7-[3-(1-methylpyrrolidin-2-yl)propoxy]-4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C28H31N5O	1
1	IC50 = 72 nM Bioactivity Info	TI LI LO TS
CP0562013 Compound Info	N-[[5-(4-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline Show/Hide	C22H18FN7	1
1	IC50 = 72.5 nM Bioactivity Info	TI LI LO TS
CP0086955 Compound Info	3-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-ethylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzonitrile Show/Hide	C25H21N5O2	1
1	IC50 = 73 nM Bioactivity Info	TI LI LO TS
CP0339842 Compound Info	6-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1-(3-pyrrolidin-1-yl-propyl)-1H-benzoimidazole Show/Hide	C26H30N6	1
1	IC50 = 74 nM Bioactivity Info	TI LI LO TS
CP0513841 Compound Info	7-[3-(4-methylpiperazin-1-yl)propoxy]-4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C28H32N6O	1
1	IC50 = 74 nM Bioactivity Info	TI LI LO TS
CP0461161 Compound Info	1-methyl-6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1Hbenzoimidazole Show/Hide	C19H17N5	1
1	IC50 = 75 nM Bioactivity Info	TI LI LO TS
CP0299346 Compound Info	4-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methylamino)benzamide Show/Hide	C25H21N7O	1
1	IC50 = 75 nM Bioactivity Info	TI LI LO TS
CP0372070 Compound Info	3-(2-(3-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1Hpyrazol-yl)-1H-pyrazol-acetamido)benzamide Show/Hide	C27H22N6O2	1
1	IC50 = 75 nM Bioactivity Info	TI LI LO TS
CP0435350 Compound Info	2-[3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazol-1-yl]-N-phenylacetamide Show/Hide	C23H19N7O	1
1	IC50 = 78 nM Bioactivity Info	TI LI LO TS
CP0473299 Compound Info	methyl 4-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzoate Show/Hide	C24H21N7O2	1
1	IC50 = 78 nM Bioactivity Info	TI LI LO TS
CP0575479 Compound Info	N-(3-cyanophenyl)-2-[3-(6-methylpyridin-2-yl)-4-thieno[3,2-c]pyridin-2-ylpyrazol-1-yl]ethanethioamide Show/Hide	C25H18N6S2	1
1	IC50 = 78 nM Bioactivity Info	TI LI LO TS
CP0198178 Compound Info	3-[6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-benzoimidazol-1-yl]-propan-1-ol Show/Hide	C21H21N5O	1
1	IC50 = 79 nM Bioactivity Info	TI LI LO TS
CP0001936 Compound Info	4-[4,5,5-trimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]phenol Show/Hide	C21H23N3O	1
1	IC50 = 80 nM Bioactivity Info	TI LI LO TS
CP0494458 Compound Info	3-[3-(6-methylpyridin-2-yl)-4-quinoxalin-6-ylpyrazol-1-yl]-N-phenylpropanamide Show/Hide	C26H22N6O	1
1	IC50 = 82 nM Bioactivity Info	TI LI LO TS
CP0153367 Compound Info	N,N-dimethyl-3-[6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzimidazol-1-yl]propan-1-amine Show/Hide	C24H28N6	1
1	IC50 = 85 nM Bioactivity Info	TI LI LO TS
CP0407932 Compound Info	Dihydropyrrolopyrazole, 15b Show/Hide	C25H27N5O	1
1	IC50 = 85 nM Bioactivity Info	TI LI LO TS
CP0435349 Compound Info	N-(2-fluorophenyl)-2-[3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazol-1-yl]acetamide Show/Hide	C23H18FN7O	1
1	IC50 = 85 nM Bioactivity Info	TI LI LO TS
CP0511514 Compound Info	N-(3-cyanophenyl)-3-(6-methylpyridin-2-yl)-4-(2-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C24H18N8S	1
1	IC50 = 85.3 nM Bioactivity Info	TI LI LO TS
CP0467859 Compound Info	2-[4-(2,1,3-benzothiadiazol-5-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-(3-fluorophenyl)acetamide Show/Hide	C23H17FN6OS	1
1	IC50 = 87 nM Bioactivity Info	TI LI LO TS
CP0499196 Compound Info	3-(3-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1H-pyrazol-1-yl)-N-phenylpropanethioamide Show/Hide	C27H23N5S	1
1	IC50 = 88 nM Bioactivity Info	TI LI LO TS
CP0505201 Compound Info	6-bromo-4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C21H17BrN4	1
1	IC50 = 89 nM Bioactivity Info	TI LI LO TS
CP0466982 Compound Info	3-cyano-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]benzamide Show/Hide	C24H18N8O	1
1	IC50 = 90 nM Bioactivity Info	TI LI LO TS
CP0282401 Compound Info	4-((5-(6-ethylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methylamino)benzamide Show/Hide	C26H23N7O	1
1	IC50 = 92 nM Bioactivity Info	TI LI LO TS
CP0459182 Compound Info	6-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)pyrimidin-4-amine Show/Hide	C16H15N5	1
1	IC50 = 93 nM Bioactivity Info	TI LI LO TS
CP0509270 Compound Info	2-(3-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1Hpyrazol-1-yl)-N-phenylethanethioamide Show/Hide	C26H21N5S	1
1	IC50 = 94 nM Bioactivity Info	TI LI LO TS
CP0326837 Compound Info	US9090625, 2 Show/Hide	C17H14N4S	1
1	IC50 = 94.1 nM Bioactivity Info	TI LI LO TS
CP0476352 Compound Info	N-(1-benzylpiperidin-4-yl)-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazole-1-carbothioamide Show/Hide	C28H28N8S	1
1	IC50 = 95.7 nM Bioactivity Info	TI LI LO TS
CP0013983 Compound Info	4-[(4R)-4,5,5-trimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]phenol Show/Hide	C21H23N3O	1
1	IC50 = 97 nM Bioactivity Info	TI LI LO TS
CP0012095 Compound Info	4-[2-(6-ethylpyridin-2-yl)-4,5,5-trimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]phenol Show/Hide	C22H25N3O	1
1	IC50 = 98 nM Bioactivity Info	TI LI LO TS
CP0407931 Compound Info	7-[2-(4-methylpiperazin-1-yl)ethoxy]-4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C27H30N6O	1
1	IC50 = 100 nM Bioactivity Info	TI LI LO TS
CP0467641 Compound Info	N-(3-cyanophenyl)-3-[3-(6-methylpyridin-2-yl)-4-quinolin-6-ylpyrazol-1-yl]propanamide Show/Hide	C28H22N6O	1
1	IC50 = 101 nM Bioactivity Info	TI LI LO TS
CP0505855 Compound Info	3-(6-methylpyridin-2-yl)-4-(2-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-phenylpyrazole-1-carbothioamide Show/Hide	C23H19N7S	1
1	IC50 = 102 nM Bioactivity Info	TI LI LO TS
CP0435348 Compound Info	3-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]benzene-1,3-dicarboxamide Show/Hide	C24H20N8O2	1
1	IC50 = 106 nM Bioactivity Info	TI LI LO TS
CP0300058 Compound Info	US9090625, 3 Show/Hide	C18H16N4S	1
1	IC50 = 108 nM Bioactivity Info	TI LI LO TS
CP0382696 Compound Info	2-[4-(2,1,3-benzothiadiazol-5-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-(3-cyanophenyl)ethanethioamide Show/Hide	C24H17N7S2	1
1	IC50 = 116 nM Bioactivity Info	TI LI LO TS
CP0378754 Compound Info	3-((5-(6-ethylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methylamino)benzonitrile Show/Hide	C26H21N7	1
1	IC50 = 119 nM Bioactivity Info	TI LI LO TS
CP0438657 Compound Info	N-(3-fluorophenyl)-2-[3-(6-methylpyridin-2-yl)-4-thieno[3,2-c]pyridin-2-ylpyrazol-1-yl]acetamide Show/Hide	C24H18FN5OS	1
1	IC50 = 119 nM Bioactivity Info	TI LI LO TS
CP0208734 Compound Info	N,N-diethyl-3-[6-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]benzimidazol-1-yl]propan-1-amine Show/Hide	C26H32N6	1
1	IC50 = 122 nM Bioactivity Info	TI LI LO TS
CP0538113 Compound Info	N-(3-fluorophenyl)-2-[3-(6-methylpyridin-2-yl)-4-thieno[3,2-c]pyridin-2-ylpyrazol-1-yl]ethanethioamide Show/Hide	C24H18FN5S2	1
1	IC50 = 125 nM Bioactivity Info	TI LI LO TS
CP0516361 Compound Info	7-(oxolan-2-ylmethoxy)-4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C25H24N4O2	1
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
CP0439001 Compound Info	3-((3-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1H-pyrazol-1-yl)methyl)benzamide Show/Hide	C26H21N5O	1
1	IC50 = 131 nM Bioactivity Info	TI LI LO TS
CP0001790 Compound Info	4-[(4R)-2-(6-ethylpyridin-2-yl)-4,5,5-trimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]phenol Show/Hide	C22H25N3O	1
1	IC50 = 137 nM Bioactivity Info	TI LI LO TS
CP0529896 Compound Info	4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]-6-(trifluoromethoxy)quinoline Show/Hide	C22H17F3N4O	1
1	IC50 = 141 nM Bioactivity Info	TI LI LO TS
CP0390144 Compound Info	2-[5-(6-methylpyridin-2-yl)-4-quinoxalin-6-ylpyrazol-1-yl]-N-phenylacetamide Show/Hide	C25H20N6O	1
1	IC50 = 143 nM Bioactivity Info	TI LI LO TS
CP0012096 Compound Info	4-[[4-[5,5-dimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]pyridin-2-yl]amino]benzenesulfonamide Show/Hide	C25H26N6O2S	1
1	IC50 = 147 nM Bioactivity Info	TI LI LO TS
CP0299324 Compound Info	4-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-ylamino)methyl)benzonitrile Show/Hide	C24H19N5O2	1
1	IC50 = 153 nM Bioactivity Info	TI LI LO TS
CP0458747 Compound Info	N-(3-cyanophenyl)-2-[3-(6-methylpyridin-2-yl)-4-quinoxalin-6-ylpyrazol-1-yl]acetamide Show/Hide	C26H19N7O	1
1	IC50 = 153 nM Bioactivity Info	TI LI LO TS
CP0014127 Compound Info	4-[[4-[4,5,5-trimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]pyridin-2-yl]amino]benzenesulfonamide Show/Hide	C26H28N6O2S	1
1	IC50 = 154 nM Bioactivity Info	TI LI LO TS
CP0343570 Compound Info	6-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1-(3-piperidin-1-yl-propyl)-1H-benzoimidazole Show/Hide	C27H32N6	1
1	IC50 = 155 nM Bioactivity Info	TI LI LO TS
CP0445091 Compound Info	4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinolin-7-ol Show/Hide	C20H16N4O	1
1	IC50 = 160 nM Bioactivity Info	TI LI LO TS
CP0452282 Compound Info	6-(2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline Show/Hide	C21H21N5	1
1	IC50 = 162 nM Bioactivity Info	TI LI LO TS
CP0013314 Compound Info	2-methyl-6-(4,5,5-trimethyl-3-pyridin-4-yl-4,6-dihydropyrrolo[1,2-b]pyrazol-2-yl)benzonitrile Show/Hide	C22H22N4	1
1	IC50 = 162 nM Bioactivity Info	TI LI LO TS
CP0462315 Compound Info	2-[4-(2,1,3-benzothiadiazol-5-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-(3-cyanophenyl)acetamide Show/Hide	C24H17N7OS	1
1	IC50 = 165 nM Bioactivity Info	TI LI LO TS
CP0476560 Compound Info	2-[4-(2,1,3-benzothiadiazol-5-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-(2-fluorophenyl)acetamide Show/Hide	C23H17FN6OS	1
1	IC50 = 168 nM Bioactivity Info	TI LI LO TS
CP0357781 Compound Info	4-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzonitrile Show/Hide	C24H19N5O2	1
1	IC50 = 174 nM Bioactivity Info	TI LI LO TS
CP0012968 Compound Info	4,5,5-trimethyl-2-(6-methylpyridin-2-yl)-3-pyridin-4-yl-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C20H22N4	1
1	IC50 = 181 nM Bioactivity Info	TI LI LO TS
CP0012959 Compound Info	2-(6-ethylpyridin-2-yl)-4,5,5-trimethyl-3-pyridin-4-yl-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C21H24N4	1
1	IC50 = 183 nM Bioactivity Info	TI LI LO TS
CP0435712 Compound Info	Dihydropyrrolopyrazole, 9 Show/Hide	C26H28N6O	1
1	IC50 = 193 nM Bioactivity Info	TI LI LO TS
CP0167329 Compound Info	2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine Show/Hide	C19H14N4	1
1	IC50 = 194 nM Bioactivity Info	TI LI LO TS
CP0008096 Compound Info	4-[(4S)-4,5,5-trimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]phenol Show/Hide	C21H23N3O	1
1	IC50 = 197 nM Bioactivity Info	TI LI LO TS
CP0308588 Compound Info	2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)quinazolin-4-amine Show/Hide	C20H17N5	1
1	IC50 = 199 nM Bioactivity Info	TI LI LO TS
CP0465049 Compound Info	2-(3-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1H-pyrazol-1-yl)-N-phenylacetamide Show/Hide	C26H21N5O	1
1	IC50 = 207 nM Bioactivity Info	TI LI LO TS
CP0004254 Compound Info	4-[[4-[2-(6-ethylpyridin-2-yl)-4,5,5-trimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]pyridin-2-yl]amino]benzenesulfonamide Show/Hide	C27H30N6O2S	1
1	IC50 = 229 nM Bioactivity Info	TI LI LO TS
CP0014129 Compound Info	4-[5,5-dimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]phenol Show/Hide	C20H21N3O	1
1	IC50 = 229 nM Bioactivity Info	TI LI LO TS
CP0471922 Compound Info	N-(3-cyanophenyl)-2-[3-(6-methylpyridin-2-yl)-4-thieno[3,2-c]pyridin-2-ylpyrazol-1-yl]acetamide Show/Hide	C25H18N6OS	1
1	IC50 = 230 nM Bioactivity Info	TI LI LO TS
CP0418020 Compound Info	3-((3-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1H-pyrazol-1-yl)methyl)benzonitrile Show/Hide	C26H19N5	1
1	IC50 = 231 nM Bioactivity Info	TI LI LO TS
CP0524764 Compound Info	N-(3-cyanophenyl)-3-[3-(6-methylpyridin-2-yl)-4-quinolin-6-ylpyrazol-1-yl]propanethioamide Show/Hide	C28H22N6S	1
1	IC50 = 232 nM Bioactivity Info	TI LI LO TS
CP0208733 Compound Info	6-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1-(3-(pyrrolidin-1-yl)propyl)-1H-benzo[d]imidazole Show/Hide	C25H28N6	1
1	IC50 = 246 nM Bioactivity Info	TI LI LO TS
CP0400861 Compound Info	3-((3-(6-Methylpyridin-2-yl)-4-(1,5-naphthyridin-2-yl)-1H-pyrazol-1-yl)methyl)benzamide Show/Hide	C25H20N6O	1
1	IC50 = 255 nM Bioactivity Info	TI LI LO TS
CP0001791 Compound Info	4-[(4S)-2-(6-ethylpyridin-2-yl)-4,5,5-trimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]phenol Show/Hide	C22H25N3O	1
1	IC50 = 261 nM Bioactivity Info	TI LI LO TS
CP0234055 Compound Info	4-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzamide Show/Hide	C24H21N5O3	1
1	IC50 = 262 nM Bioactivity Info	TI LI LO TS
CP0071413 Compound Info	3-(2-(6-methylpyridin-2-yl)quinazolin-4-ylamino)benzamide Show/Hide	C21H17N5O	1
1	IC50 = 263 nM Bioactivity Info	TI LI LO TS
CP0423572 Compound Info	N-(2-fluorophenyl)-2-[3-(6-methylpyridin-2-yl)-4-thieno[3,2-c]pyridin-2-ylpyrazol-1-yl]acetamide Show/Hide	C24H18FN5OS	1
1	IC50 = 312 nM Bioactivity Info	TI LI LO TS
CP0400864 Compound Info	3-((3-(6-Methylpyridin-2-yl)-4-(1,5-naphthyridin-2-yl)-1H-pyrazol-1-yl)methyl)benzonitrile Show/Hide	C25H18N6	1
1	IC50 = 318 nM Bioactivity Info	TI LI LO TS
CP0014082 Compound Info	2-[3-(4-hydroxyphenyl)-4,5,5-trimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-2-yl]-6-methylbenzonitrile Show/Hide	C23H23N3O	1
1	IC50 = 341 nM Bioactivity Info	TI LI LO TS
CP0281590 Compound Info	4-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-ethylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzonitrile Show/Hide	C25H21N5O2	1
1	IC50 = 360 nM Bioactivity Info	TI LI LO TS
CP0234057 Compound Info	4-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-ethylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzamide Show/Hide	C25H23N5O3	1
1	IC50 = 385 nM Bioactivity Info	TI LI LO TS
CP0324264 Compound Info	N,N-dimethyl-3-[6-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)benzimidazol-1-yl]propan-1-amine Show/Hide	C23H26N6	1
1	IC50 = 398 nM Bioactivity Info	TI LI LO TS
CP0013315 Compound Info	5,5-dimethyl-2-(6-methylpyridin-2-yl)-3-pyridin-4-yl-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C19H20N4	1
1	IC50 = 406 nM Bioactivity Info	TI LI LO TS
CP0008099 Compound Info	3-(2-chloropyridin-4-yl)-4,5,5-trimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C20H21ClN4	1
1	IC50 = 517 nM Bioactivity Info	TI LI LO TS
CP0445092 Compound Info	Dihydropyrrolopyrazole, 8 Show/Hide	C23H20N4O2	1
1	IC50 = 526 nM Bioactivity Info	TI LI LO TS
CP0014081 Compound Info	4,5,5-trimethyl-3-(2-methylpyridin-4-yl)-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C21H24N4	1
1	IC50 = 548 nM Bioactivity Info	TI LI LO TS
CP0309222 Compound Info	N-(1-methylindazol-5-yl)-2-(6-methylpyridin-2-yl)quinazolin-4-amine Show/Hide	C22H18N6	1
1	IC50 = 588 nM Bioactivity Info	TI LI LO TS
CP0012960 Compound Info	3-(4-methoxyphenyl)-4,5,5-trimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C22H25N3O	1
1	IC50 = 612 nM Bioactivity Info	TI LI LO TS
CP0182028 Compound Info	N-[2-(6-methylpyridin-2-yl)quinazolin-4-yl]-1,3-benzothiazol-6-amine Show/Hide	C21H15N5S	1
1	IC50 = 646 nM Bioactivity Info	TI LI LO TS
CP0488291 Compound Info	N-(3-cyanophenyl)-2-[5-(6-methylpyridin-2-yl)-4-quinoxalin-6-ylpyrazol-1-yl]acetamide Show/Hide	C26H19N7O	1
1	IC50 = 737 nM Bioactivity Info	TI LI LO TS
CP0014128 Compound Info	4-(methoxymethyl)-5,5-dimethyl-2-(6-methylpyridin-2-yl)-3-pyridin-4-yl-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C21H24N4O	1
1	IC50 = 743 nM Bioactivity Info	TI LI LO TS
CP0373092 Compound Info	Dihydropyrrolopyrazole, 23 Show/Hide	C29H27N5O	1
1	IC50 = 750 nM Bioactivity Info	TI LI LO TS
CP0001789 Compound Info	2-(6-ethylpyridin-2-yl)-3-(4-methoxyphenyl)-4,5,5-trimethyl-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C23H27N3O	1
1	IC50 = 805 nM Bioactivity Info	TI LI LO TS
CP0399712 Compound Info	8-fluoro-4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C21H17FN4	1
1	IC50 = 928 nM Bioactivity Info	TI LI LO TS
CP0445088 Compound Info	Dihydropyrrolopyrazole, 22 Show/Hide	C29H25N5O2	1
1	IC50 = 1100 nM Bioactivity Info	TI LI LO TS
CP0445090 Compound Info	4-({4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinolin-7-yl}oxy)benzamide Show/Hide	C27H21N5O2	1
1	IC50 = 1100 nM Bioactivity Info	TI LI LO TS
CP0536806 Compound Info	4-({4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinolin-7-yl}oxy)benzonitrile Show/Hide	C27H19N5O	1
1	IC50 = 1200 nM Bioactivity Info	TI LI LO TS
CP0001792 Compound Info	3-(2-chloropyridin-4-yl)-5,5-dimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C19H19ClN4	1
1	IC50 = 1228 nM Bioactivity Info	TI LI LO TS
CP0012961 Compound Info	2-(4,5,5-trimethyl-3-pyridin-4-yl-4,6-dihydropyrrolo[1,2-b]pyrazol-2-yl)benzonitrile Show/Hide	C21H20N4	1
1	IC50 = 1288 nM Bioactivity Info	TI LI LO TS
CP0008097 Compound Info	[5,5-dimethyl-2-(6-methylpyridin-2-yl)-3-pyridin-4-yl-4,6-dihydropyrrolo[1,2-b]pyrazol-4-yl]methanol Show/Hide	C20H22N4O	1
1	IC50 = 1413 nM Bioactivity Info	TI LI LO TS
CP0036041 Compound Info	4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide Show/Hide	C22H16N4O3	1
1	IC50 = 1542 nM Bioactivity Info	TI LI LO TS
CP0540026 Compound Info	N-(3-fluorophenyl)-2-[3-(6-methylpyridin-2-yl)-4-(2-phenylpyridin-4-yl)pyrazol-1-yl]ethanethioamide Show/Hide	C28H22FN5S	1
1	IC50 = 1560 nM Bioactivity Info	TI LI LO TS
CP0530780 Compound Info	2-[3-(6-methylpyridin-2-yl)-4-(2-phenylpyridin-4-yl)pyrazol-1-yl]-N-phenylethanethioamide Show/Hide	C28H23N5S	1
1	IC50 = 1689 nM Bioactivity Info	TI LI LO TS
CP0134782 Compound Info	5-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-benzo[d]imidazole Show/Hide	C18H15N5	1
1	IC50 = 1700 nM Bioactivity Info	TI LI LO TS
CP0339841 Compound Info	5-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1-[3-(tetrahydro-pyran-2-yloxy)-propyl]-1H-benzoimidazole Show/Hide	C27H31N5O2	1
1	IC50 = 1830 nM Bioactivity Info	TI LI LO TS
CP0011284 Compound Info	5,5-dimethyl-2-pyridin-2-yl-3-pyridin-4-yl-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C18H18N4	1
1	IC50 = 1940 nM Bioactivity Info	TI LI LO TS
CP0006106 Compound Info	4-(5,5-dimethyl-2-pyridin-2-yl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl)phenol Show/Hide	C19H19N3O	1
1	IC50 = 1985 nM Bioactivity Info	TI LI LO TS
CP0004253 Compound Info	ethyl 4-[4,5,5-trimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]benzoate Show/Hide	C24H27N3O2	1
1	IC50 = 2008 nM Bioactivity Info	TI LI LO TS
CP0473100 Compound Info	N-(2-fluorophenyl)-2-[3-(6-methylpyridin-2-yl)-4-(2-phenylpyridin-4-yl)pyrazol-1-yl]ethanethioamide Show/Hide	C28H22FN5S	1
1	IC50 = 2050 nM Bioactivity Info	TI LI LO TS
CP0416352 Compound Info	N-(3-cyanophenyl)-2-[3-(6-methylpyridin-2-yl)-4-(2-phenylpyridin-4-yl)pyrazol-1-yl]ethanethioamide Show/Hide	C29H22N6S	1
1	IC50 = 2200 nM Bioactivity Info	TI LI LO TS
CP0439002 Compound Info	3-((5-(6-Methylpyridin-2-yl)-4-(1,5-naphthyridin-2-yl)-1H-imidazol-2-yl)methyl)benzonitrile Show/Hide	C25H18N6	1
1	IC50 = 2250 nM Bioactivity Info	TI LI LO TS
CP0011283 Compound Info	2-(5,5-dimethyl-3-pyridin-4-yl-4,6-dihydropyrrolo[1,2-b]pyrazol-2-yl)benzonitrile Show/Hide	C20H18N4	1
1	IC50 = 2518 nM Bioactivity Info	TI LI LO TS
CP0469775 Compound Info	3-((5-(6-Methylpyridin-2-yl)-4-(1,5-naphthyridin-2-yl)-1H-imidazol-2-yl)methyl)benzamide Show/Hide	C25H20N6O	1
1	IC50 = 2600 nM Bioactivity Info	TI LI LO TS
CP0001935 Compound Info	3-(2-chloropyridin-4-yl)-2-(6-ethylpyridin-2-yl)-4,5,5-trimethyl-4,6-dihydropyrrolo[1,2-b]pyrazole Show/Hide	C21H23ClN4	1
1	IC50 = 2745 nM Bioactivity Info	TI LI LO TS
CP0278644 Compound Info	N-(2H-benzotriazol-5-yl)-2-(6-methylpyridin-2-yl)quinazolin-4-amine Show/Hide	C20H15N7	1
1	IC50 = 3715 nM Bioactivity Info	TI LI LO TS
CP0445093 Compound Info	6,8-dimethoxy-4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C23H22N4O2	1
1	IC50 = 3810 nM Bioactivity Info	TI LI LO TS
CP0208737 Compound Info	1-methyl-5-[2-(6-methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-1H-indole Show/Hide	C21H20N4	1
1	IC50 = 4100 nM Bioactivity Info	TI LI LO TS
CP0132093 Compound Info	1-methyl-5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-benzoimidazole Show/Hide	C19H17N5	1
1	IC50 = 4740 nM Bioactivity Info	TI LI LO TS
CP0445089 Compound Info	4-({4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinolin-7-yl}oxy)benzoic acid Show/Hide	C27H20N4O3	1
1	IC50 = 4800 nM Bioactivity Info	TI LI LO TS
CP0011282 Compound Info	2-[3-(4-hydroxyphenyl)-4,5,5-trimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-2-yl]benzonitrile Show/Hide	C22H21N3O	1
1	IC50 = 5194 nM Bioactivity Info	TI LI LO TS
CP0199523 Compound Info	5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1-[3-(tetrahydro-pyran-2-yloxy)-propyl]-1H-benzoimidazole Show/Hide	C26H29N5O2	1
1	IC50 = 6580 nM Bioactivity Info	TI LI LO TS
CP0400862 Compound Info	3-((5-(6-Methylpyridin-2-yl)-4-(1,5-naphthyridin-2-yl)-1H-pyrazol-1-yl)methyl)benzonitrile Show/Hide	C25H18N6	1
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0400863 Compound Info	3-((5-(6-Methylpyridin-2-yl)-4-(1,5-naphthyridin-2-yl)-1H-pyrazol-1-yl)methyl)benzamide Show/Hide	C25H20N6O	1
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0497360 Compound Info	3-((5-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1H-pyrazol-1-yl)methyl)benzamide Show/Hide	C26H21N5O	1
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0509424 Compound Info	3-((5-(6-Methylpyridin-2-yl)-4-(quinolin-6-yl)-1H-pyrazol-1-yl)methyl)benzonitrile Show/Hide	C26H19N5	1
1	IC50 > 10000 nM Bioactivity Info	TI LI LO TS
CP0439470 Compound Info	1-methyl-5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-indole Show/Hide	C20H18N4	1
1	IC50 = 12230 nM Bioactivity Info	TI LI LO TS
CP0004106 Compound Info	(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one Show/Hide	C28H26N4O3	1
1	IC50 > 18500 nM Bioactivity Info	TI LI LO TS
CP0437174 Compound Info	2-chloro-4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C20H15ClN4	1
1	IC50 = 19800 nM Bioactivity Info	TI LI LO TS
CP0508199 Compound Info	5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1H-indole Show/Hide	C19H16N4	1
1	IC50 > 20000 nM Bioactivity Info	TI LI LO TS
CP0394260 Compound Info	4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]-2-(pyrrolidin-1-yl)quinoline Show/Hide	C24H23N5	1
1	IC50 > 20000 nM Bioactivity Info	TI LI LO TS
CP0407933 Compound Info	2-methoxy-4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C21H18N4O	1
1	IC50 > 20000 nM Bioactivity Info	TI LI LO TS
CP0412510 Compound Info	2-(ethylsulfanyl)-4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline Show/Hide	C22H20N4S	1
1	IC50 > 20000 nM Bioactivity Info	TI LI LO TS
CP0373075 Compound Info	4-((5-(4-fluorophenyl)-4-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C22H18FN5O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0383419 Compound Info	3-((4-(2-aminopyrimidin-4-yl)-5-(4-fluorophenyl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C21H17FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0399183 Compound Info	4-((4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C22H16FN5O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0434887 Compound Info	3-((4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C22H18FN5O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0434931 Compound Info	3-((4-(4-fluorophenyl)-5-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C29H25FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0445270 Compound Info	3-((4-(2-(cyclopropylamino)pyrimidin-4-yl)-5-(4-fluorophenyl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C24H21FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0456123 Compound Info	3-((4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C22H16FN5O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0465940 Compound Info	3-((4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-2-yl)methyl)benzamide Show/Hide	C22H18FN5O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0465941 Compound Info	3-((5-(2-(cyclopropylamino)pyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-2-yl)methyl)benzonitrile Show/Hide	C24H19FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0465942 Compound Info	3-((5-(2-(cyclopropylamino)pyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C24H19FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0465943 Compound Info	4-((5-(4-fluorophenyl)-4-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C22H16FN5O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0465944 Compound Info	3-((4-(2-aminopyrimidin-4-yl)-5-(4-fluorophenyl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C21H15FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0474571 Compound Info	4-((4-(4-fluorophenyl)-5-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C29H25FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0474573 Compound Info	4-((4-(4-fluorophenyl)-5-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C29H23FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0474574 Compound Info	4-((5-(4-fluorophenyl)-4-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C29H25FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0475063 Compound Info	3-((5-(2-aminopyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-2-yl)methyl)benzonitrile Show/Hide	C21H15FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0475064 Compound Info	3-((5-(4-fluorophenyl)-4-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C29H25FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0480566 Compound Info	3-((5-(2-(4-methoxybenzylamino)pyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C29H23FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0480567 Compound Info	3-((5-(4-fluorophenyl)-4-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C29H23FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0480576 Compound Info	3-((4-(2-(4-methoxybenzylamino)pyrimidin-4-yl)-5-(4-fluorophenyl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C29H23FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0480577 Compound Info	3-((5-(4-fluorophenyl)-4-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C22H16FN5O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0486734 Compound Info	3-((5-(2-(cyclopropylamino)pyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-2-yl)methyl)benzamide Show/Hide	C24H21FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0487000 Compound Info	3-((5-(2-aminopyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C21H15FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0489808 Compound Info	4-((4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C22H18FN5O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0493659 Compound Info	3-((4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-2-yl)methyl)benzonitrile Show/Hide	C22H16FN5O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0493660 Compound Info	3-((5-(2-(cyclopropylamino)pyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C24H21FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0500710 Compound Info	3-((4-(4-fluorophenyl)-5-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-1H-imidazol-2-yl)methyl)benzamide Show/Hide	C29H25FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0500711 Compound Info	3-((5-(4-fluorophenyl)-4-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C22H18FN5O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0522410 Compound Info	3-((5-(2-(4-methoxybenzylamino)pyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-2-yl)methyl)benzonitrile Show/Hide	C29H23FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0522411 Compound Info	3-((4-(2-(cyclopropylamino)pyrimidin-4-yl)-5-(4-fluorophenyl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C24H19FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0522769 Compound Info	4-((5-(4-fluorophenyl)-4-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C29H23FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0522971 Compound Info	3-((4-(4-fluorophenyl)-5-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-1H-imidazol-2-yl)methyl)benzonitrile Show/Hide	C29H23FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0522973 Compound Info	3-((4-(4-fluorophenyl)-5-(2-((S)-1-phenylethylamino)pyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzonitrile Show/Hide	C29H23FN6	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0526786 Compound Info	3-((5-(2-aminopyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-1-yl)methyl)benzamide Show/Hide	C21H17FN6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0372071 Compound Info	N-(3-cyanophenyl)-2-[4-(4-methoxyquinolin-6-yl)-5-(6-methylpyridin-2-yl)pyrazol-1-yl]acetamide Show/Hide	C28H22N6O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0425899 Compound Info	N-(3-cyanophenyl)-2-[5-(6-methylpyridin-2-yl)-4-quinolin-6-ylpyrazol-1-yl]acetamide Show/Hide	C27H20N6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0476728 Compound Info	2-(5-(6-methylpyridin-2-yl)-4-(quinolin-6-yl)-1H-pyrazol-1-yl)-N-phenylacetamide Show/Hide	C26H21N5O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0476729 Compound Info	2-(4-(4-methoxyquinolin-6-yl-)-5-(6-methylpyridin-2-yl-)-1H-pyrazol-1-yl)-N-phenylacetamide Show/Hide	C27H23N5O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0476730 Compound Info	3-(2-(5-(6-methylpyridin-2-yl)-4-(quinolin-6-yl)-1H-pyrazol-1-yl)-acetamido)benzamide Show/Hide	C27H22N6O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0479060 Compound Info	N-(3-cyanophenyl)-3-[4-(4-methoxyquinolin-6-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]propanamide Show/Hide	C29H24N6O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0502589 Compound Info	2-(4-(4-Methoxyquinolin-6-yl)-3-(6-methylpyridin-2-yl)-1H-pyrazol-1-yl)-N-phenylacetamide Show/Hide	C27H23N5O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0502590 Compound Info	N-(3-cyanophenyl)-2-[4-(4-methoxyquinolin-6-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]acetamide Show/Hide	C28H22N6O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0456212 Compound Info	N-(3-cyanophenyl)-2-[4-(2,3-dimethylquinoxalin-6-yl)-5-(6-methylpyridin-2-yl)pyrazol-1-yl]acetamide Show/Hide	C28H23N7O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0458748 Compound Info	N-(3-cyanophenyl)-3-[4-(2,3-dimethylquinoxalin-6-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]propanamide Show/Hide	C29H25N7O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0478787 Compound Info	3-[[2-[4-(2,3-dimethylquinoxalin-6-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]acetyl]amino]benzamide Show/Hide	C28H25N7O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0484689 Compound Info	N-(3-cyanophenyl)-2-[4-(2,3-dimethylquinoxalin-6-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]ethanethioamide Show/Hide	C28H23N7S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0488289 Compound Info	2-[4-(2,3-dimethylquinoxalin-6-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-phenylacetamide Show/Hide	C27H24N6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0494457 Compound Info	2-[4-(2,3-dimethylquinoxalin-6-yl)-5-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-phenylacetamide Show/Hide	C27H24N6O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0494459 Compound Info	2-[4-(2,3-dimethylquinoxalin-6-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]-N-phenylethanethioamide Show/Hide	C27H24N6S	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0498726 Compound Info	N-(3-cyanophenyl)-2-[4-(2,3-dimethylquinoxalin-6-yl)-3-(6-methylpyridin-2-yl)pyrazol-1-yl]acetamide Show/Hide	C28H23N7O	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS

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About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han