Brief Information of the Compound and Protein
Compound Name
4-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzamide
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PubChem ID
CID: 16731883
SID: 26690038
Canonical SMILES
Cc1cccc(n1)-c1nc(CNc2ccc(cc2)C(N)=O)[nH]c1-c1ccc2OCOc2c1
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Compound Formula C24H21N5O3
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 262 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 21 nM