Brief Information of the Compound and Protein
Compound Name
4-(6-methylpyridin-2-yl)-5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1,3-thiazol-2-amine
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PubChem ID
CID: 70693281
SID: 163533462
Canonical SMILES
Cc1cccc(n1)-c1nc(NCc2ccc(OC(F)(F)F)cc2)sc1-c1ccc2ncnn2c1
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Compound Formula C23H17F3N6OS
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 60.9 nM
   TI
   LI
   LO
   TS