Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S,4S)-4-amino-1-({4-[(3-fluoropyridin-4-yl)amino]-2-(pyridin-2-yl)pyrrolo[2,1-f][1,2,4]triazin-5-yl}methyl)piperidin-3-ol
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 PubChem ID
CID: 126484202
Canonical SMILES
N[C@H]1CCN(Cc2ccn3nc(nc(Nc4ccncc4F)c23)-c2ccccn2)C[C@@H]1O
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Compound Formula C22H23FN8O
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 3.9 nM
   TI
   LI
   LO
   TS