Brief Information of the Compound and Protein
Compound Name
N-[4-[[2-[6-(trifluoromethyl)pyridin-2-yl]-7H-purin-6-yl]amino]pyridin-2-yl]acetamide
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PubChem ID
CID: 126622422
Canonical SMILES
CC(=O)Nc1cc(Nc2nc(nc3[nH]cnc23)-c2cccc(n2)C(F)(F)F)ccn1
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Compound Formula C18H13F3N8O
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.1 nM
   TI
   LI
   LO
   TS