Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[(4R)-4,5,5-trimethyl-2-(6-methylpyridin-2-yl)-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl]phenol
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 PubChem ID
CID: 145992193
Canonical SMILES
C[C@H]1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccc(O)cc1
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Compound Formula C21H23N3O
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 97 nM
   TI
   LI
   LO
   TS