Brief Information of the Compound and Protein
Compound Name
[5,5-dimethyl-2-(6-methylpyridin-2-yl)-3-pyridin-4-yl-4,6-dihydropyrrolo[1,2-b]pyrazol-4-yl]methanol
    Show/Hide
PubChem ID
CID: 145980647
Canonical SMILES
Cc1cccc(n1)-c1nn2CC(C)(C)C(CO)c2c1-c1ccncc1
    Show/Hide
Compound Formula C20H22N4O
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1413 nM
   TI
   LI
   LO
   TS