Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methyl)benzamide
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 PubChem ID
CID: 11676119
SID: 103051373
Canonical SMILES
Cc1cccc(n1)-c1nc(Cc2cccc(c2)C(N)=O)[nH]c1-c1ccc2nccnc2c1
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Compound Formula C25H20N6O
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000150 HaCaT
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 19.6 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
2
IC50 = 17.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 36 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13 nM