| Compound ID |
Compound Name |
Compound Formula |
|
CP0395310
|
6-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
|
C19H21IN4O
|
2
|
| 1 |
EC50 = 0.52 nM
|
|
|
| 2 |
Ki = 0.33 nM
|
|
|
|
CP0436143
|
1-(2-methoxyphenyl)-4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazine
Show/Hide
|
C21H24N4O
|
2
|
| 1 |
EC50 = 0.6 nM
|
|
|
| 2 |
Ki = 0.28 nM
|
|
|
|
CP0006107
|
CAS_85760-74-3
Show/Hide
|
C13H21N3
|
8
|
| 1 |
EC50 = 1.4 nM
|
|
|
| 2 |
EC50 = 2 nM
|
|
|
| 3 |
EC50 = 9.9 nM
|
|
|
| 4 |
EC50 = 11 nM
|
|
|
| 5 |
EC50 = 23 nM
|
|
|
| 6 |
Ki = 1.8 nM
|
|
|
| 7 |
Ki = 8.5 nM
|
|
|
| 8 |
Ki = 53 nM
|
|
|
|
CP0405288
|
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine-7-carbonitrile
Show/Hide
|
C19H18ClN5
|
2
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
Ki = 1.5 nM
|
|
|
|
CP0129571
|
2-[4-(4-chlorophenyl)piperazin-1-yl)methyl]imidazo[1,2-a]pyridine
Show/Hide
|
C18H19ClN4
|
2
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0058895
|
2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
|
C19H22N4O
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
Ki = 2.8 nM
|
|
|
|
CP0378749
|
4-phenyl-1-((1-phenyl-1H-pyrazol-4-yl)methyl)-1,2,3,6-tetrahydropyridine
Show/Hide
|
C21H21N3
|
3
|
| 1 |
EC50 = 5.6 nM
|
|
|
| 2 |
EC50 = 9.5 nM
|
|
|
| 3 |
Ki = 0.59 nM
|
|
|
|
CP0084794
|
3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridine
Show/Hide
|
C18H19ClN4
|
4
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
Ki = 2.291 nM
|
|
|
| 3 |
Ki = 3.1 nM
|
|
|
| 4 |
Ki = 3.6 nM
|
|
|
|
CP0449675
|
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-pyrazolo[1,5-a]pyridine-7-carbonitrile
Show/Hide
|
C20H20ClN5
|
2
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
Ki = 2.3 nM
|
|
|
|
CP0046420
|
CAS_3853
Show/Hide
|
C18H19ClN4
|
6
|
| 1 |
EC50 = 27 nM
|
|
|
| 2 |
Ki = 0.43 nM
|
|
|
| 3 |
Ki = 0.6166 nM
|
|
|
| 4 |
Ki = 0.62 nM
|
|
|
| 5 |
Ki = 0.7 nM
|
|
|
| 6 |
Ki = 0.91 nM
|
|
|
|
CP0380469
|
(R)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine
Show/Hide
|
C21H26N4
|
2
|
| 1 |
EC50 = 50 nM
|
|
|
| 2 |
Ki = 1.5 nM
|
|
|
|
CP0040248
|
7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-one
Show/Hide
|
C18H18N2O2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0402061
|
7-[4-(3-Chloro-4-methyl-phenyl)-piperazin-1-ylmethyl]-chromen-2-one
Show/Hide
|
C21H21ClN2O2
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0008601
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
Show/Hide
|
C21H23ClFNO2
|
14
|
| 1 |
IC50 = 6 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
| 3 |
Ki = 2.1 nM
|
|
|
| 4 |
Ki = 2.2 nM
|
|
|
| 5 |
Ki = 2.3 nM
|
|
|
| 6 |
Ki = 3.3 nM
|
|
|
| 7 |
Ki = 5.9 nM
|
|
|
| 8 |
Ki = 6 nM
|
|
|
| 9 |
Ki = 6.026 nM
|
|
|
| 10 |
Ki = 6.3 nM
|
|
|
| 11 |
Ki = 6.31 nM
|
|
|
| 12 |
Ki = 7.3 nM
|
|
|
| 13 |
Ki = 42 nM
|
|
|
| 14 |
Ki = 103 nM
|
|
|
|
CP0397536
|
1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-phenyl-piperazine
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|
C22H22FN3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0449009
|
1-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-4-pyridin-2-yl-piperazine
Show/Hide
|
C21H21FN4
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0442924
|
1-(4-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine
Show/Hide
|
C22H21F2N3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0449156
|
2-[4-(2'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C21H21FN4
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0403995
|
2-[4-(2'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C22H24N4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0406823
|
2-[4-(3'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C22H24N4O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0459319
|
2-[4-(9H-Fluoren-1-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C22H22N4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0423061
|
4-[5-(4-Fluoro-phenyl)-pyridin-3-ylmethyl]-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl
Show/Hide
|
C20H20FN5
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0895614
|
(2H-Benzo[1,4]oxazin-3-yl)-[3-(4-pyridin-2-yl-piperazin-1-yl)-propyl]-amine; compound with but-2-enedioic acid
Show/Hide
|
C24H29N5O5
|
2
|
| 1 |
IC50 = 27.3 nM
|
|
|
| 2 |
Ki = 21 nM
|
|
|
|
CP0384141
|
3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-2,5,5-trimethyl-thiazolidin-4-one
Show/Hide
|
C22H30FN3OS2
|
2
|
| 1 |
IC50 = 29 nM
|
|
|
| 2 |
Ki = 5 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
10
|
| 1 |
IC50 = 41 nM
|
|
|
| 2 |
IC50 = 58 nM
|
|
|
| 3 |
Ki = 10 nM
|
|
|
| 4 |
Ki = 16 nM
|
|
|
| 5 |
Ki = 17 nM
|
|
|
| 6 |
Ki = 30 nM
|
|
|
| 7 |
Ki = 39 nM
|
|
|
| 8 |
Ki = 39.81 nM
|
|
|
| 9 |
Ki = 47 nM
|
|
|
| 10 |
Ki = 70 nM
|
|
|
|
CP0448784
|
2-[4-(4'-Methoxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C22H24N4O
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0895458
|
(2H-Benzo[1,4]oxazin-3-yl)-[3-(4-phenyl-piperazin-1-yl)-propyl]-amine; compound with but-2-enedioic acid
Show/Hide
|
C25H30N4O5
|
2
|
| 1 |
IC50 = 95 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
|
CP0916363
|
(2H-Benzo[1,4]oxazin-3-yl)-[5-(4-pyrimidin-2-yl-piperazin-1-yl)-pentyl]-amine; compound with but-2-enedioic acid
Show/Hide
|
C25H32N6O5
|
2
|
| 1 |
IC50 = 95 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0441413
|
7-[(2-p-Tolylamino-ethylamino)-methyl]-chromen-2-one
Show/Hide
|
C19H20N2O2
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0045063
|
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Show/Hide
|
C17H20N4S
|
3
|
| 1 |
IC50 = 173 nM
|
|
|
| 2 |
Ki = 19.95 nM
|
|
|
| 3 |
Ki = 29 nM
|
|
|
|
CP0377462
|
2-(4-Dibenzofuran-4-ylmethyl-piperazin-1-yl)-pyrimidine
Show/Hide
|
C21H20N4O
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0383824
|
3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-2-methyl-1-thia-3-aza-spiro[4.4]nonan-4-one
Show/Hide
|
C24H32FN3OS2
|
2
|
| 1 |
IC50 = 713 nM
|
|
|
| 2 |
Ki = 117 nM
|
|
|
|
CP0443741
|
2-[4-(9H-Fluoren-4-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C22H22N4
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0428725
|
6-(4-p-Tolyl-piperazin-1-ylmethyl)-chromen-2-one
Show/Hide
|
C21H22N2O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0339664
|
CHEBI:64217
Show/Hide
|
C21H26ClN3O2
|
1
|
| 1 |
Kd = 0.21 nM
|
|
|
|
CP0355375
|
6-bromo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
|
C19H21BrN4O
|
1
|
| 1 |
Ki = 0.25 nM
|
|
|
|
CP0239544
|
1-(N-benzylanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H35N5O2
|
1
|
| 1 |
Ki = 0.25 nM
|
|
|
|
CP0077360
|
N-[2-(3-chlorophenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C17H20ClNO2
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0059512
|
N-[2-(3,4-dimethylphenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 0.35 nM
|
|
|
|
CP0375516
|
1-Benzyl-4-(3-methyl-4-phenyl-pyrazol-1-yl)-piperidine
Show/Hide
|
C22H25N3
|
1
|
| 1 |
Ki = 0.39 nM
|
|
|
|
CP0413871
|
1-(azulen-1-ylmethyl)-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C22H24N2O
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0360721
|
1-(2-methoxyphenyl)-4-((1-(pyridin-2-yl)-1H-pyrazol-4-yl)methyl)piperazine
Show/Hide
|
C20H23N5O
|
2
|
| 1 |
Ki = 0.4365 nM
|
|
|
| 2 |
Ki = 0.44 nM
|
|
|
|
CP0400139
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-3-ethynylbenzamide
Show/Hide
|
C21H21Cl2N3O
|
1
|
| 1 |
Ki = 0.45 nM
|
|
|
|
CP0059544
|
(3-Phenoxy-propyl)-(2-m-tolyloxy-ethyl)-amine
Show/Hide
|
C18H23NO2
|
1
|
| 1 |
Ki = 0.46 nM
|
|
|
|
CP0161762
|
3-[4-(4-Iodo-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
Show/Hide
|
C18H19IN4
|
1
|
| 1 |
Ki = 0.51 nM
|
|
|
|
CP0077362
|
N-[2-(3-chloro-4-methylphenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C18H22ClNO2
|
1
|
| 1 |
Ki = 0.52 nM
|
|
|
|
CP0178983
|
(3-Phenoxy-propyl)-(2-p-tolyloxy-ethyl)-amine
Show/Hide
|
C18H23NO2
|
1
|
| 1 |
Ki = 0.52 nM
|
|
|
|
CP0383474
|
2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-carbonitrile
Show/Hide
|
C20H20N4
|
1
|
| 1 |
Ki = 0.52 nM
|
|
|
|
CP0059618
|
N-[2-(4-chlorophenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C17H20ClNO2
|
1
|
| 1 |
Ki = 0.53 nM
|
|
|
|
CP0408564
|
8-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methylimidazo[1,2-a]pyridine
Show/Hide
|
C20H23IN4O
|
1
|
| 1 |
Ki = 0.53 nM
|
|
|
|
CP0418846
|
4-Amino-N-((R)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide
Show/Hide
|
C19H22ClN3O2
|
1
|
| 1 |
Ki = 0.55 nM
|
|
|
|
CP0148103
|
1-[N-[(4-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H34FN5O2
|
1
|
| 1 |
Ki = 0.55 nM
|
|
|
|
CP0438120
|
1-(N-benzyl-4-fluoroanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H34FN5O2
|
1
|
| 1 |
Ki = 0.55 nM
|
|
|
|
CP0717121
|
4-phenyl-1-((1-phenyl-1H-pyrazol-4-yl)methyl)piperidine
Show/Hide
|
C21H23N3
|
1
|
| 1 |
Ki = 0.5888 nM
|
|
|
|
CP0439590
|
N-[(3S)-1-(9-bicyclo[3.3.1]nonanyl)pyrrolidin-3-yl]-5-chloro-2-methoxy-4-(methylamino)benzamide
Show/Hide
|
C22H32ClN3O2
|
1
|
| 1 |
Ki = 0.67 nM
|
|
|
|
CP0079550
|
N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C21H25N5O2
|
1
|
| 1 |
Ki = 0.6761 nM
|
|
|
|
CP0405801
|
6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C22H28N4O2
|
1
|
| 1 |
Ki = 0.69 nM
|
|
|
|
CP0178943
|
1-(2-fluorophenyl)-4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazine
Show/Hide
|
C20H21FN4
|
2
|
| 1 |
Ki = 0.7 nM
|
|
|
| 2 |
Ki = 0.7079 nM
|
|
|
|
CP0419187
|
[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methanol
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
Ki = 0.71 nM
|
|
|
|
CP0373605
|
1-(4-Fluorophenyl)-4-[4-([2.2]paracyclophan-4-yl)-4-hydroxypiperidin-1-yl]butan-1-one
Show/Hide
|
C31H34FNO2
|
1
|
| 1 |
Ki = 0.72 nM
|
|
|
|
CP0410997
|
4-bromo-N-[2-[4-[2-(1H-indol-3-yl)ethyl]piperazin-1-yl]ethyl]-N-propylaniline
Show/Hide
|
C25H33BrN4
|
1
|
| 1 |
Ki = 0.72 nM
|
|
|
|
CP0391962
|
1-(2-methoxyphenyl)-4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]piperazine
Show/Hide
|
C34H40N4O2
|
1
|
| 1 |
Ki = 0.79 nM
|
|
|
|
CP0454875
|
(3-Phenylsulfanyl-propyl)-(2-p-tolyloxy-ethyl)-amine
Show/Hide
|
C18H23NOS
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0159469
|
N-[2-(4-chlorophenoxy)ethyl]-3-(4-fluorophenoxy)propan-1-amine
Show/Hide
|
C17H19ClFNO2
|
1
|
| 1 |
Ki = 0.84 nM
|
|
|
|
CP0408574
|
2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methyl-8-phenylimidazo[1,2-a]pyridine
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
Ki = 0.84 nM
|
|
|
|
CP0451866
|
2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-5-(pyrazol-1-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C22H24N6O
|
1
|
| 1 |
Ki = 0.94 nM
|
|
|
|
CP0059517
|
3-(4-fluorophenoxy)-N-[2-(4-methylphenoxy)ethyl]propan-1-amine
Show/Hide
|
C18H22FNO2
|
1
|
| 1 |
Ki = 0.96 nM
|
|
|
|
CP0374898
|
8-bromo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methylimidazo[1,2-a]pyridine
Show/Hide
|
C20H23BrN4O
|
1
|
| 1 |
Ki = 0.99 nM
|
|
|
|
CP0449377
|
6-bromo-2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
|
C18H17BrCl2N4
|
1
|
| 1 |
Ki = 0.99 nM
|
|
|
|
CP0376122
|
1-[2-[2,3-dihydro-1H-inden-2-yl(propyl)amino]ethyl]-3-(4-fluorophenyl)iminourea
Show/Hide
|
C21H25FN4O
|
1
|
| 1 |
Ki = 0.99 nM
|
|
|
|
CP0451864
|
2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)-1H-indole-5-carbonitrile
Show/Hide
|
C20H19FN4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0172628
|
1-Phenyl-4-[(1-phenyl-1H-pyrazol-4-yl)methyl]piperazine
Show/Hide
|
C20H22N4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0378752
|
1-((3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)-4-phenylpiperazine
Show/Hide
|
C21H24N4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0430313
|
4-Amino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide
Show/Hide
|
C19H22ClN3O2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0059513
|
(2-p-Tolyloxy-ethyl)-(3-o-tolyloxy-propyl)-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0141761
|
(2-p-Tolyloxy-ethyl)-(3-m-tolyloxy-propyl)-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0178941
|
3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-7-ethynyl-pyrazolo[1,5-a]pyridine
Show/Hide
|
C20H19ClN4
|
2
|
| 1 |
Ki = 1.2 nM
|
|
|
| 2 |
Ki = 1.23 nM
|
|
|
|
CP0427419
|
2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridine
Show/Hide
|
C19H22N4O
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0387645
|
(6S)-6-[propyl(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0178951
|
N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-4-methylbenzamide
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
Ki = 1.202 nM
|
|
|
|
CP0494189
|
4-Acryloylamino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide
Show/Hide
|
C22H24ClN3O3
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0374897
|
2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methylimidazo[1,2-a]pyridine-8-carbonitrile
Show/Hide
|
C21H23N5O
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0453011
|
6-chloro-2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]imidazo[1,2-b]pyridazine
Show/Hide
|
C17H16Cl3N5
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0048038
|
2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-one
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0405816
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbonitrile
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0454510
|
N-[2-(4-chlorophenoxy)ethyl]-3-phenylsulfanylpropan-1-amine
Show/Hide
|
C17H20ClNOS
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0528646
|
2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
|
C20H19ClN4
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0240039
|
2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
Show/Hide
|
C18H18Cl2N4
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0415191
|
(E)-N-[2-[2,3-dihydro-1H-inden-2-yl(propyl)amino]ethyl]-3-(4-fluorophenyl)prop-2-enamide
Show/Hide
|
C23H27FN2O
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0420813
|
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(propanoylamino)benzamide
Show/Hide
|
C22H26ClN3O3
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0380592
|
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-ethynyl-2-methyl-pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H21ClN4
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0112004
|
1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine
Show/Hide
|
C19H21ClN2S
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0381527
|
1-[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]-N,N-dimethylmethanamine
Show/Hide
|
C25H31N3O
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0393754
|
(6S)-6-[propyl(4-pyrazolo[1,5-a]pyridin-6-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0407867
|
(R)-8-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazin-1-yl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0154475
|
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole
Show/Hide
|
C19H20ClN3
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0375128
|
(7R,9aS)-7-Phenoxymethyl-2-phenyl-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C21H26N2O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0374844
|
6-chloro-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-b]pyridazine
Show/Hide
|
C18H20ClN5O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0374896
|
2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methyl-8-(pyrazol-1-yl)imidazo[1,2-a]pyridine
Show/Hide
|
C23H26N6O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0423060
|
4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole
Show/Hide
|
C19H20ClN3
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0412517
|
(7R,9aS)-7-Phenoxymethyl-2-pyridin-2-yl-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C20H25N3O
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0536405
|
1-(N-benzyl-4-methoxyanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C29H37N5O3
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0430181
|
6-[4-(3,4-Dimethyl-phenyl)-piperidin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0436775
|
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-[(2,2,2-trifluoroacetyl)amino]benzamide
Show/Hide
|
C21H21ClF3N3O3
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0142590
|
2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-3,4-dihydroisoquinolin-1(2H)-one
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0488643
|
1-(2-methoxyphenyl)-4-[[3-(piperidin-1-ylmethyl)azulen-1-yl]methyl]piperazine
Show/Hide
|
C28H35N3O
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0059535
|
(2-Phenoxy-ethyl)-(3-phenoxy-propyl)-amine
Show/Hide
|
C17H21NO2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0406178
|
(7S,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C19H22F2N4O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0453012
|
6-chloro-2-[4-(4-chlorophenyl)piperazin-1-ylmethyl]imidazo[1,2-b]pyridazine
Show/Hide
|
C17H17Cl2N5
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0431302
|
1-(3,4-difluorophenyl)imino-3-[2-[2,3-dihydro-1H-inden-2-yl(propyl)amino]ethyl]urea
Show/Hide
|
C21H24F2N4O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0387642
|
(6S)-6-[4-[3-[(Z)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]oxybutyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C25H32N4O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0045414
|
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclopropanecarbonylamino)-2-methoxybenzamide
Show/Hide
|
C23H26ClN3O3
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0402468
|
5-Chloro-N-((S)-1-cyclohexyl-pyrrolidin-3-yl)-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide
Show/Hide
|
C22H30ClN3O3
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0376507
|
2-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
|
C20H19ClN4
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0052067
|
2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyrazolo[1,5-a]pyridine
Show/Hide
|
C18H19ClN4
|
2
|
| 1 |
Ki = 2.188 nM
|
|
|
| 2 |
Ki = 2.2 nM
|
|
|
|
CP0387296
|
5-[4-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0453020
|
2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]-6-methyl-8-morpholinoimidazo[1,2-a]pyridine
Show/Hide
|
C24H31N5O2
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0332114
|
3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-6-(2-thienyl)isoquinolin-1(2H)-one
Show/Hide
|
C28H33N3O2S
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0159532
|
N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-3-methylbenzamide
Show/Hide
|
C20H22N4O
|
2
|
| 1 |
Ki = 2.3 nM
|
|
|
| 2 |
Ki = 16.98 nM
|
|
|
|
CP0299382
|
2-(dimethylamino)-6-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
Show/Hide
|
C20H26N6O2
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0381528
|
3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulene-1-carbonitrile
Show/Hide
|
C23H23N3O
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0380079
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] propanoate
Show/Hide
|
C24H27ClFNO3
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0324171
|
1-phenyl-4-((1-(pyridin-2-yl)-1H-pyrazol-4-yl)methyl)piperazine
Show/Hide
|
C19H21N5
|
2
|
| 1 |
Ki = 2.57 nM
|
|
|
| 2 |
Ki = 2.6 nM
|
|
|
|
CP0445440
|
4-(4-Benzyl-piperazin-1-yl)-7-bromo-1H-indole
Show/Hide
|
C19H20BrN3
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0393325
|
7-(4-p-Tolyl-piperidin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0508435
|
7-[4-(3,4-Dimethyl-phenyl)-piperidin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0480184
|
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine-7-carbaldehyde
Show/Hide
|
C19H19ClN4O
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0490071
|
1-[N-[(2-fluorophenyl)methyl]-4-methoxyanilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C29H36FN5O3
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0536911
|
1-[4-chloro-N-[(2-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H33ClFN5O2
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0324173
|
3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-7-methylH-pyrazolo[1,5-a]pyridine
Show/Hide
|
C19H21ClN4
|
2
|
| 1 |
Ki = 2.692 nM
|
|
|
| 2 |
Ki = 2.7 nM
|
|
|
|
CP0401203
|
5-Chloro-N-((S)-1-cycloheptyl-pyrrolidin-3-yl)-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide
Show/Hide
|
C23H32ClN3O3
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0146487
|
(2-Phenoxy-ethyl)-(3-p-tolyloxy-propyl)-amine
Show/Hide
|
C18H23NO2
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0391220
|
1-(2-methoxyphenyl)-4-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)piperazine
Show/Hide
|
C20H23N5O
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0455632
|
(7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C19H23FN4O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0415085
|
6-(4-p-Tolyl-piperidin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0381010
|
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-trimethylsilanyl-pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H27ClN4Si
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0316181
|
3-Methyl-7-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-2-pyrrolidin-1-yl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C21H27N7O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0291606
|
6-fluoro-2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-3,4-dihydroisoquinolin-1(2H)-one
Show/Hide
|
C24H30FN3O2
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0178944
|
1-(4-Fluorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)methyl]piperazine
Show/Hide
|
C20H21FN4
|
2
|
| 1 |
Ki = 2.884 nM
|
|
|
| 2 |
Ki = 2.9 nM
|
|
|
|
CP0192825
|
1-(4-Chlorophenyl)-4-[(1-phenyl-1H-pyrazol-4-yl)methyl]piperazine
Show/Hide
|
C20H21ClN4
|
2
|
| 1 |
Ki = 2.884 nM
|
|
|
| 2 |
Ki = 2.9 nM
|
|
|
|
CP0406822
|
4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-benzoimidazole
Show/Hide
|
C19H19F3N4
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0217047
|
2-[4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl]-2,3,4,5-tetrahydro-7-(2-thienyl)benzo[c]azepin-1-one
Show/Hide
|
C29H35N3O2S
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0468622
|
1-(N-benzyl-4-chloroanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H34ClN5O2
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0559025
|
1-[N-[(4-fluorophenyl)methyl]-4-methoxyanilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C29H36FN5O3
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0480937
|
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-2-methoxy-4-(2-methylpropanoylamino)benzamide
Show/Hide
|
C23H28ClN3O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0870009
|
(2H-Benzo[1,4]oxazin-3-yl)-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amine; compound with but-2-enedioic acid
Show/Hide
|
C26H32N4O6
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0156986
|
4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-indol-2-one
Show/Hide
|
C19H21N3O
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0248857
|
7-methoxy-2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-one
Show/Hide
|
C26H35N3O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0077361
|
4-[2-(3-Phenoxy-propylamino)-ethoxy]-phenol
Show/Hide
|
C17H21NO3
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0374346
|
Benzyl-[2-(2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine
Show/Hide
|
C17H16F3N3O
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0504148
|
(7R,9aS)-2-(5-Chloro-pyridin-2-yl)-7-(4-fluoro-phenoxymethyl)-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C20H23ClFN3O
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0053618
|
4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide
Show/Hide
|
C20H24ClN3O2
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0378750
|
4-phenyl-1-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)-1,2,3,6-tetrahydropyridine
Show/Hide
|
C20H20N4
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0785349
|
4-phenyl-1-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)piperidine
Show/Hide
|
C20H22N4
|
1
|
| 1 |
Ki = 3.236 nM
|
|
|
|
CP0420757
|
5-Chloro-N-((S)-1-cyclohexylmethyl-pyrrolidin-3-yl)-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide
Show/Hide
|
C23H32ClN3O3
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0395466
|
(3-Phenoxy-propyl)-(3-phenyl-propyl)-amine
Show/Hide
|
C18H23NO
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0142591
|
3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]isoquinolin-1(2H)-one
Show/Hide
|
C28H33N3O3
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0486215
|
1-[[4-[(1-butyltriazol-4-yl)methoxy]-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C26H35N5O3
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0477093
|
1-[4-bromo-N-[(2-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H33BrFN5O2
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0215268
|
N-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-4-methylbenzamide
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 3.388 nM
|
|
|
|
CP0472164
|
5-Chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-N-((S)-1-phenethyl-pyrrolidin-3-yl)-benzamide
Show/Hide
|
C24H28ClN3O3
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0139431
|
(7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C19H22F2N4O
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0373264
|
2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-6-carbonitrile
Show/Hide
|
C20H19ClN4
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0299385
|
7-{[4-(3,4-Dichlorophenyl)piperazin-1-yl]methyl}-3-methyl-2-pyrrolidin-1-yl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C22H26Cl2N6O
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0290487
|
3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-6-(4-pyridyl)isoquinolin-1(2H)-one
Show/Hide
|
C29H34N4O2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0291460
|
3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-6-phenylisoquinolin-1(2H)-one
Show/Hide
|
C30H35N3O2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0438114
|
1-(N-benzyl-4-bromoanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H34BrN5O2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0110881
|
4-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C19H22ClN3O2
|
1
|
| 1 |
Ki = 3.467 nM
|
|
|
|
CP0512131
|
(7R,9aS)-7-Phenoxymethyl-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C19H24N4O
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0406355
|
2-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole-6-carbonitrile
Show/Hide
|
C20H20N4
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0482776
|
1-[4-fluoro-N-[(2-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H33F2N5O2
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0455425
|
N-[(3S)-1-(9-bicyclo[3.3.1]nonanyl)pyrrolidin-3-yl]-5-chloro-4-(cyclopropanecarbonylamino)-2-methoxybenzamide
Show/Hide
|
C25H34ClN3O3
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0099176
|
CAS_188942
Show/Hide
|
C18H20N6
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0403737
|
7-Phenoxymethyl-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C19H24N4O
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0480432
|
6-[4-(4-Methoxy-phenyl)-piperidin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C21H24N2O3
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0467571
|
4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazole-2-thione
Show/Hide
|
C16H17N3OS
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0247839
|
3-Methyl-7-[(4-phenylpiperazin-1-yl)methyl]-2-pyrrolidin-1-yl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C22H28N6O
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0413872
|
1-(2-methoxyphenyl)-4-[[3-[(4-methylpiperazin-1-yl)methyl]azulen-1-yl]methyl]piperazine
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0536406
|
1-[4-fluoro-N-[(3-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H33F2N5O2
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0269450
|
4-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C19H19ClN4O
|
1
|
| 1 |
Ki = 3.89 nM
|
|
|
|
CP0383464
|
2-[4-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile
Show/Hide
|
C19H19N5
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0425377
|
6-chloro-2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-b]pyridazine
Show/Hide
|
C17H17ClFN5
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0291608
|
3,4-Dihydro-6-ethynyl-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]isoquinolin-1(2H)-one
Show/Hide
|
C26H31N3O2
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0052140
|
7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C19H20ClN3O2
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0439833
|
6-(4-p-Tolyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0266686
|
N-[4-[(4-ethynylcyclohex-3-en-1-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0393750
|
6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0453461
|
N-[(3S)-1-(2-adamantyl)pyrrolidin-3-yl]-5-chloro-4-(cyclopropanecarbonylamino)-2-methoxybenzamide
Show/Hide
|
C26H34ClN3O3
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0050117
|
N-[2-(2-chlorophenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C17H20ClNO2
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0269451
|
N-[2-(4-nitrophenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C17H20N2O4
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0380806
|
6-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H24Cl2N4O
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0528981
|
1-(N-benzyl-4-fluoroanilino)-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]urea
Show/Hide
|
C29H36FN5O2
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0147752
|
1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine
Show/Hide
|
C19H21ClN2S
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0399135
|
4-[2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO4
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0428802
|
4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]morpholine
Show/Hide
|
C27H33N3O2
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0450724
|
1-[4-fluoro-N-[(4-fluorophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C28H33F2N5O2
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0374180
|
(3-Phenoxy-propyl)-(3-p-tolyl-propyl)-amine
Show/Hide
|
C19H25NO
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0386863
|
(NE)-N-[[6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-3-yl]methylidene]hydroxylamine
Show/Hide
|
C23H29N5O3
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0375874
|
N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C24H30N2OS
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0412946
|
5-hydroxy-8-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C23H27N5O4
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0404790
|
7-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C20H23N3O3
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0405787
|
3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]-7-iodopyrazolo[1,5-a]pyridine
Show/Hide
|
C18H18ClIN4
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0404326
|
6-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C21H25N3O2
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0423155
|
1-[[1-[4-(3-fluoropropoxy)phenyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C23H28FN5O2
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0496697
|
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclobutanecarbonylamino)-2-methoxybenzamide
Show/Hide
|
C24H28ClN3O3
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0403535
|
1-Phenyl-4-(2-phenyl-3H-imidazol-4-ylmethyl)-piperazine
Show/Hide
|
C20H22N4
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0387292
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carbonitrile
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0051889
|
1-((5-methyl-1-phenyl-1H-pyrazol-4-yl)methyl)-4-phenylpiperazine
Show/Hide
|
C21H24N4
|
2
|
| 1 |
Ki = 5.248 nM
|
|
|
| 2 |
Ki = 5.3 nM
|
|
|
|
CP0040962
|
3-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
|
C19H19ClN4O
|
1
|
| 1 |
Ki = 5.248 nM
|
|
|
|
CP0492724
|
(7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(4-fluoro-phenyl)-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C21H24F2N2O
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0375612
|
N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C24H30N2OS
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0098943
|
N-[2-(4-methoxyphenoxy)ethyl]-3-phenoxypropan-1-amine
Show/Hide
|
C18H23NO3
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0374760
|
1-[[3-methoxy-4-[[1-[8-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]octyl]triazol-4-yl]methoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C52H68N10O6
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0405581
|
N-[(3R)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclopropanecarbonylamino)-2-methoxybenzamide
Show/Hide
|
C23H26ClN3O3
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0159467
|
N-[2-(4-chlorophenoxy)ethyl]-3-(4-methylphenoxy)propan-1-amine
Show/Hide
|
C18H22ClNO2
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0375010
|
2-{4-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile
Show/Hide
|
C19H18ClN5
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0046179
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1-(4-nitrophenyl)triazole-4-carboxamide
Show/Hide
|
C23H25Cl2N7O3
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0389424
|
5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbonitrile
Show/Hide
|
C22H23Cl2N5O
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0381103
|
N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O
|
2
|
| 1 |
Ki = 5.8 nM
|
|
|
| 2 |
Ki = 60 nM
|
|
|
|
CP0380082
|
Haldol
Show/Hide
|
C31H41ClFNO3
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0298304
|
1-(4-Ethynyl-1H-pyrrol-2-ylmethyl)-4-phenyl-piperazine
Show/Hide
|
C17H19N3
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0438121
|
1-[4-fluoro-N-[(3-methoxyphenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C29H36FN5O3
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0468619
|
1-[4-fluoro-N-[(4-phenylphenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C34H38FN5O2
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0464436
|
2-[4-(5-Methyl-2-phenyl-3H-imidazol-4-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C19H22N6
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0379917
|
1-(4-chlorophenyl)-4-[[3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]azulen-1-yl]methyl]piperazine
Show/Hide
|
C33H37ClN4O
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0376081
|
7-(4-Phenyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C19H21N3O2
|
1
|
| 1 |
Ki = 6.1 nM
|
|
|
|
CP0142592
|
2-[4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl]-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carbonitrile
Show/Hide
|
C25H30N4O2
|
1
|
| 1 |
Ki = 6.1 nM
|
|
|
|
CP0036921
|
3-HYDROXYTYRAMINE HYDROCHLORIDE
Show/Hide
|
C8H11NO2
|
1
|
| 1 |
Ki = 6.2 nM
|
|
|
|
CP0429280
|
1-[N-[(3-fluorophenyl)methyl]-4-methoxyanilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C29H36FN5O3
|
1
|
| 1 |
Ki = 6.2 nM
|
|
|
|
CP0464792
|
4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C16H17N3O2
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0135427
|
7-Chloro-3-[(4-phenylpiperazin-1-yl)methyl]-1Hpyrrolo[2,3-c]pyridine
Show/Hide
|
C18H19ClN4
|
1
|
| 1 |
Ki = 6.4 nM
|
|
|
|
CP0330237
|
5-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)-N,N,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine
Show/Hide
|
C21H28N6O
|
1
|
| 1 |
Ki = 6.4 nM
|
|
|
|
CP0460184
|
1-[[4-[3-[1-(2-ethoxyethyl)triazol-4-yl]propoxy]-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C28H39N5O4
|
1
|
| 1 |
Ki = 6.4 nM
|
|
|
|
CP0387262
|
(6S)-6-[4-[3-[(E)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-6-yl]oxybutyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C25H32N4O3
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1
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| 1 |
Ki = 6.5 nM
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CP0377047
|
7-[4-(4-Methoxy-phenyl)-piperidin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C21H24N2O3
|
1
|
| 1 |
Ki = 6.7 nM
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CP0374763
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1-[[3-methoxy-4-[[1-[2-[2-[2-[4-[[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]methyl]triazol-1-yl]ethoxy]ethoxy]ethyl]triazol-4-yl]methoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C50H64N10O8
|
1
|
| 1 |
Ki = 6.8 nM
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CP0410107
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7-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C21H25N3O2
|
1
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| 1 |
Ki = 6.9 nM
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CP0401594
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N-[(3R)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclobutanecarbonylamino)-2-methoxybenzamide
Show/Hide
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C24H28ClN3O3
|
1
|
| 1 |
Ki = 7 nM
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CP0377888
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Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine
Show/Hide
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C17H15ClF3N3O
|
1
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| 1 |
Ki = 7 nM
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CP0448096
|
(R)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one
Show/Hide
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C18H19N3O2
|
1
|
| 1 |
Ki = 7 nM
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CP0379280
|
2-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C28H30N4O4S
|
1
|
| 1 |
Ki = 7.1 nM
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CP0393751
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
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C23H28N4O3
|
1
|
| 1 |
Ki = 7.1 nM
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CP0374761
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1-[[4-[3-(1-butyltriazol-4-yl)propoxy]-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C28H39N5O3
|
1
|
| 1 |
Ki = 7.2 nM
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CP0402903
|
2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
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C20H18Cl2N4
|
1
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| 1 |
Ki = 7.5 nM
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CP0381009
|
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-phenyl-pyrazolo[1,5-a]pyridine
Show/Hide
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C24H23ClN4
|
1
|
| 1 |
Ki = 7.6 nM
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CP0080249
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4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one; hydrochloride
Show/Hide
|
C20H22ClFN2O
|
1
|
| 1 |
Ki = 7.6 nM
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CP0083554
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(S)-3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
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C22H27N3O
|
1
|
| 1 |
Ki = 7.8 nM
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CP0407988
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(NE)-N-[[5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-2-yl]methylidene]hydroxylamine
Show/Hide
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C23H29N5O3
|
1
|
| 1 |
Ki = 7.8 nM
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CP0387293
|
6-[4-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
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C25H31N3O3
|
1
|
| 1 |
Ki = 7.9 nM
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CP0103405
|
3-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole
Show/Hide
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C19H21N3
|
1
|
| 1 |
Ki = 8 nM
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CP0373347
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-4-ethynylbenzamide
Show/Hide
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C21H21Cl2N3O
|
1
|
| 1 |
Ki = 8 nM
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CP0127400
|
(-)-Pramipexole
Show/Hide
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C10H17N3S
|
2
|
| 1 |
Ki = 8.1 nM
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|
|
| 2 |
Ki = 130 nM
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CP0405812
|
N-[3-[(Z)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide
Show/Hide
|
C23H28N6O3
|
1
|
| 1 |
Ki = 8.1 nM
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|
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CP0401196
|
N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxy-4-(methylamino)benzamide
Show/Hide
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C21H26ClN3O2
|
1
|
| 1 |
Ki = 8.3 nM
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CP0472407
|
5-hydroxy-8-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]piperazin-1-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H30N4O5
|
1
|
| 1 |
Ki = 8.3 nM
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CP0269449
|
4-Chloro-N-[4-(2-chloro-phenyl)-piperazin-1-ylmethyl]-benzamide
Show/Hide
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C18H19Cl2N3O
|
1
|
| 1 |
Ki = 8.318 nM
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CP0473629
|
1-[[4-[[1-(2-ethoxyethyl)triazol-4-yl]methoxy]-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C26H35N5O4
|
1
|
| 1 |
Ki = 8.4 nM
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CP0380757
|
1-(2-Phenyl-3H-imidazol-4-ylmethyl)-4-pyridin-2-yl-piperazine
Show/Hide
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C19H21N5
|
1
|
| 1 |
Ki = 8.5 nM
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CP0532455
|
(S)-3-[4-(3-Chloro-4-hydroxymethyl-phenyl)-piperazin-1-yl]-1-(4-chloro-phenyl)-propan-1-ol
Show/Hide
|
C20H24Cl2N2O2
|
1
|
| 1 |
Ki = 8.6 nM
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CP0483750
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-(dimethylamino)propanoate
Show/Hide
|
C26H32ClFN2O3
|
1
|
| 1 |
Ki = 8.7 nM
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CP0188439
|
4-(4-Benzyl-piperazin-1-yl)-5-chloro-1,3-dihydro-indol-2-one
Show/Hide
|
C19H20ClN3O
|
1
|
| 1 |
Ki = 8.8 nM
|
|
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CP0468119
|
3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
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CP0375780
|
N-[3-[4-(2-methylsulfanylphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C22H27N5OS
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
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CP0113655
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-7-carboxamide
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
Ki = 8.913 nM
|
|
|
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CP0377770
|
2-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-6-carbonitrile
Show/Hide
|
C20H18Cl2N4
|
1
|
| 1 |
Ki = 9 nM
|
|
|
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CP0438118
|
1-(N-benzyl-4-fluoroanilino)-3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]urea
Show/Hide
|
C27H32FN5O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
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CP0438506
|
3-{2-[4-(3,4-Dimethyl-phenyl)-piperidin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
|
C23H28N2O
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
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CP0464731
|
2-[5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile
Show/Hide
|
C19H19N5
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
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CP0380812
|
5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carbonitrile
Show/Hide
|
C22H23Cl2N5O
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
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CP0510969
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] acetate
Show/Hide
|
C23H25ClFNO3
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
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CP0395266
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C34H49N5O4
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
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CP0414823
|
1-[(3-ethynylazulen-1-yl)methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C24H24N2O
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
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CP0477094
|
1-(N-benzylanilino)-3-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C27H32ClN5O
|
1
|
| 1 |
Ki = 9.7 nM
|
|
|
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CP0291607
|
3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-5-phenylisoquinolin-1(2H)-one
Show/Hide
|
C30H35N3O2
|
1
|
| 1 |
Ki = 9.8 nM
|
|
|
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CP0393152
|
4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzenesulfonamide
Show/Hide
|
C21H28FN3O3S
|
1
|
| 1 |
Ki = 9.9 nM
|
|
|
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CP0378751
|
1-Phenyl-4-[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]piperazine
Show/Hide
|
C19H21N5
|
1
|
| 1 |
Ki = 9.9 nM
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|
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CP0454655
|
3-[2-(4-Naphthalen-2-yl-piperazin-1-yl)-ethyl]-2,3-dihydro-isoindol-1-one
Show/Hide
|
C24H25N3O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0258018
|
4-(2-Benzylamino-ethoxy)-1,3-dihydro-indol-2-one
Show/Hide
|
C17H18N2O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0497728
|
8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one
Show/Hide
|
C18H19N3O2
|
1
|
| 1 |
Ki = 10 nM
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|
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CP0039958
|
(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H27FN4O2
|
1
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| 1 |
Ki = 10 nM
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|
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CP0291324
|
1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]piperazine
Show/Hide
|
C24H24FN3O2
|
1
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| 1 |
Ki = 10 nM
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CP0405923
|
4-[4-(4-Chlorophenyl)piperazin-1-yl]-1-(2,5-dimethylphenyl)-butan-1-one
Show/Hide
|
C23H28ClNO
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0380841
|
1-[2-[2,3-dihydro-1H-inden-2-yl(propyl)amino]ethyl]-3-(3,4,5-trifluorophenyl)iminourea
Show/Hide
|
C21H23F3N4O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0436910
|
5-[4-[4-(5-hydroxy-3-oxo-4H-1,4-benzoxazin-8-yl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C24H27N5O5
|
1
|
| 1 |
Ki = 10 nM
|
|
|
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CP0409818
|
7-(4-p-Tolyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
Ki = 10.7 nM
|
|
|
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CP0146505
|
(2-p-Tolyloxy-ethyl)-(3-p-tolyloxy-propyl)-amine
Show/Hide
|
C19H25NO2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
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CP0531470
|
3-[4-(3-Chloro-4-hydroxymethyl-phenyl)-piperazin-1-yl]-1-(4-chloro-phenyl)-propan-1-ol
Show/Hide
|
C20H24Cl2N2O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
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CP0392953
|
2-{5-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile
Show/Hide
|
C19H18ClN5
|
1
|
| 1 |
Ki = 11 nM
|
|
|
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CP0465795
|
((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-amine
Show/Hide
|
C23H26BrN3O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
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CP0046703
|
1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one
Show/Hide
|
C24H26ClFN4O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
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CP0373622
|
(R)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl][2.2]-paracyclophane-4-carboxamide
Show/Hide
|
C32H39N3O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
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CP0479115
|
1-[[3-methoxy-4-[4-[1-[10-[4-[4-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]butyl]triazol-1-yl]decyl]triazol-4-yl]butoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C60H84N10O6
|
1
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| 1 |
Ki = 11 nM
|
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CP0406353
|
N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O
|
2
|
| 1 |
Ki = 11 nM
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| 2 |
Ki = 30 nM
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CP0393753
|
ethyl 5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carboxylate
Show/Hide
|
C25H32N4O4
|
1
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| 1 |
Ki = 11 nM
|
|
|
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CP0383485
|
4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazole-2-thione
Show/Hide
|
C16H16ClN3OS
|
1
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| 1 |
Ki = 11.2 nM
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CP0059819
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11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(18),3(8),4,6,14,16-hexaen-6-ol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki = 11.3 nM
|
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CP0918857
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1-(2-Ethoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C23H30ClN3O2S
|
1
|
| 1 |
Ki = 12 nM
|
|
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CP0061808
|
1-Phenyl-4-(4-phenyl-1H-pyrrol-2-ylmethyl)-piperazine
Show/Hide
|
C21H23N3
|
1
|
| 1 |
Ki = 12 nM
|
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|
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CP0393065
|
N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-3-(2-phenylethynyl)benzamide
Show/Hide
|
C27H25Cl2N3O
|
1
|
| 1 |
Ki = 12 nM
|
|
|
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CP0167457
|
3-{[4-(4-Methoxyphenyl)piperazin-1-yl]methyl}-2,7-dimethylimidazo[1,2-c]pyrimidine
Show/Hide
|
C20H25N5O
|
1
|
| 1 |
Ki = 12 nM
|
|
|
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CP0473628
|
1-[[3-methoxy-4-[3-[1-[8-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]phenyl]methyl]-4-methylpiperazine
Show/Hide
|
C50H72N10O5
|
1
|
| 1 |
Ki = 12 nM
|
|
|
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CP0486216
|
1-[[3-methoxy-4-[3-[1-[2-[2-[2-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]ethoxy]ethoxy]ethyl]triazol-4-yl]propoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C54H72N10O8
|
1
|
| 1 |
Ki = 12 nM
|
|
|
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CP0429287
|
1-[2,4-dichloro-N-[(4-cyanophenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C29H32Cl2N6O2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
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CP0376592
|
6-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
|
C20H23N3O3
|
1
|
| 1 |
Ki = 12.3 nM
|
|
|
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CP0461461
|
3-[2-(4-p-Tolyl-piperazin-1-yl)-ethyl]-2,3-dihydro-isoindol-1-one
Show/Hide
|
C21H25N3O
|
1
|
| 1 |
Ki = 12.4 nM
|
|
|
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CP0076889
|
N-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-3-methylbenzamide
Show/Hide
|
C20H25N3O2
|
1
|
| 1 |
Ki = 12.88 nM
|
|
|
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CP0374762
|
1-[[4-[4-(1-butyltriazol-4-yl)butoxy]-3-methoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C29H41N5O3
|
1
|
| 1 |
Ki = 13 nM
|
|
|
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CP0393752
|
5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C22H28N4O2
|
1
|
| 1 |
Ki = 13 nM
|
|
|
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CP0167456
|
3-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,5,7-trimethylimidazo[1,2-c]pyrimidine
Show/Hide
|
C21H27N5O
|
1
|
| 1 |
Ki = 14 nM
|
|
|
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CP0100739
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
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CP0375473
|
1-(2-methoxyphenyl)-4-[[3-methoxy-4-[3-[1-[8-(4-propyltriazol-1-yl)octyl]triazol-4-yl]propoxy]phenyl]methyl]piperazine
Show/Hide
|
C37H54N8O3
|
1
|
| 1 |
Ki = 14 nM
|
|
|
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CP0404378
|
N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
Ki = 14 nM
|
|
|
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CP0391219
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1-[[1-[4-(2-fluoroethoxy)phenyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
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C22H26FN5O2
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1
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| 1 |
Ki = 14 nM
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CP0307921
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N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
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C24H26FN3O3S2
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1
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| 1 |
Ki = 14 nM
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CP0405814
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4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-pyrazolo[1,5-a]pyridin-5-ylbutanamide
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C21H23Cl2N5O
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1
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| 1 |
Ki = 14 nM
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CP0405822
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4-[4-(2-methoxyphenyl)piperazin-1-yl]-N-pyrazolo[1,5-a]pyridin-5-ylbutanamide
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C22H27N5O2
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1
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| 1 |
Ki = 14 nM
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CP0438115
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1-(N-benzylanilino)-3-[3-[4-(4-bromophenyl)piperazin-1-yl]propyl]urea
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C27H32BrN5O
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1
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| 1 |
Ki = 14 nM
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CP0122849
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4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-benzoimidazol-2-one
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C18H20N4O
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1
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| 1 |
Ki = 14.4 nM
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CP0458947
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4-(4-Benzyl-piperazin-1-yl)-1H-indole
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C19H21N3
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1
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| 1 |
Ki = 14.7 nM
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CP0440814
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1-[[3-methoxy-4-[3-[1-[8-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C56H76N10O6
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1
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| 1 |
Ki = 15 nM
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CP0477090
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1-[N-[(4-cyanophenyl)methyl]-4-fluoroanilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
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C29H33FN6O2
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1
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| 1 |
Ki = 15 nM
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CP0550959
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1-(N-benzyl-2,4-dichloroanilino)-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
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C28H33Cl2N5O2
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1
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| 1 |
Ki = 15 nM
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CP0104676
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Benzo[b]thiophene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
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C24H29N3O2S
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2
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| 1 |
Ki = 15.14 nM
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| 2 |
Ki = 24 nM
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CP0178952
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3-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide
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C19H22ClN3O2
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1
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| 1 |
Ki = 15.14 nM
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CP0378012
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4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazol-2-one
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C16H16ClN3O2
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1
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| 1 |
Ki = 15.8 nM
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CP0839087
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5-bromo-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
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C24H29BrN4O2
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1
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| 1 |
Ki = 15.85 nM
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CP0178940
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N-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]-3-methylbenzamide
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C19H22ClN3O
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1
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| 1 |
Ki = 15.85 nM
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CP0393059
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3-ethynyl-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
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C24H29N3O2
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1
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| 1 |
Ki = 16 nM
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CP0299386
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7-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-3-methyl-2-pyrrolidin-1-yl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Show/Hide
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C22H27FN6O
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1
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| 1 |
Ki = 16 nM
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CP0428803
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1-(2-methoxyphenyl)-4-[[3-(2-phenylethynyl)azulen-1-yl]methyl]piperazine
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C30H28N2O
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1
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| 1 |
Ki = 16 nM
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CP0461941
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1-[[1-[4-[3-(2-fluoroethoxy)propoxy]phenyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C25H32FN5O3
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1
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| 1 |
Ki = 16 nM
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CP0414636
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7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
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C21H24Cl2N4O
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1
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| 1 |
Ki = 16 nM
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CP0414637
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4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
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C21H24Cl2N4O
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1
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| 1 |
Ki = 16 nM
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CP0386266
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(E)-N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-3-(4-fluorophenyl)prop-2-enamide
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C25H31FN2O
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1
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| 1 |
Ki = 16 nM
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CP0438119
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1-[N-[(4-cyanophenyl)methyl]-4-methoxyanilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C30H36N6O3
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1
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| 1 |
Ki = 16 nM
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CP0264023
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(S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]dioxin-6-ol; oxalic acid
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C16H17NO3
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1
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| 1 |
Ki = 16.6 nM
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CP0717115
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5-bromo-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
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C24H28BrN3O3
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1
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| 1 |
Ki = 16.98 nM
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CP0410598
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3-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
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C20H19ClN4
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1
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| 1 |
Ki = 17 nM
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CP0393154
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-fluorobenzenesulfonamide
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C20H24Cl2FN3O2S
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1
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| 1 |
Ki = 17 nM
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CP0382812
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4-[4-(2,5-Dimethylphenyl)piperazin-1-yl]-1-(4-fluorophenyl)-butan-1-one
Show/Hide
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C22H27FN2O
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1
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| 1 |
Ki = 17 nM
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CP0408071
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N-(3-cyanopyrazolo[1,5-a]pyridin-5-yl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide
Show/Hide
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C23H26N6O2
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1
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| 1 |
Ki = 17 nM
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CP0536409
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1-[3-[4-(4-chlorophenyl)piperazin-1-yl]propyl]-3-[N-[(4-fluorophenyl)methyl]anilino]urea
Show/Hide
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C27H31ClFN5O
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1
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| 1 |
Ki = 17 nM
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CP0498130
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N-[(3R)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclopentanecarbonylamino)-2-methoxybenzamide
Show/Hide
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C25H30ClN3O3
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1
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| 1 |
Ki = 18 nM
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CP0491798
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(7R,9aS)-7-(4-Methoxy-phenoxymethyl)-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
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C20H26N4O2
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1
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| 1 |
Ki = 18 nM
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CP0079074
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4-[(4-phenylpiperazin-1-yl)methyl]-1H-pyrrole-2-carbonitrile
Show/Hide
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C16H18N4
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1
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| 1 |
Ki = 18 nM
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CP0464341
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N-[4-[4-(2,3-difluorophenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
Show/Hide
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C31H35F2N3O
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1
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| 1 |
Ki = 18 nM
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CP0380808
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6-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
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C22H24Cl2N4O2
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1
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| 1 |
Ki = 18 nM
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CP0536912
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1-(N-benzylanilino)-3-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]urea
Show/Hide
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C25H31N7O
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1
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| 1 |
Ki = 18 nM
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CP0409934
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6-(4-Phenyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C19H21N3O2
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1
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| 1 |
Ki = 18.3 nM
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CP0475763
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4-[4-([2.2]Paracyclophan-4-yl)piperazin-1-yl]-1-([2.2]paracyclophan-4-yl)butan-1-one
Show/Hide
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C41H45NO
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1
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| 1 |
Ki = 19 nM
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CP0375474
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1-cyclohexyl-4-[[3-methoxy-4-[3-[1-[8-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]phenyl]methyl]piperazine
Show/Hide
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C55H80N10O5
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1
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| 1 |
Ki = 19 nM
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CP0460185
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1-[[3-methoxy-4-[3-[1-[2-[2-[2-[2-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]propoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C56H76N10O9
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1
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| 1 |
Ki = 19 nM
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CP0479116
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1-[[3-methoxy-4-[3-[1-[10-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]decyl]triazol-4-yl]propoxy]phenyl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C58H80N10O6
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1
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| 1 |
Ki = 19 nM
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CP0414003
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1-(2-methoxyphenyl)-4-[(3-pent-1-ynylazulen-1-yl)methyl]piperazine
Show/Hide
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C27H30N2O
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1
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| 1 |
Ki = 19 nM
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CP0489218
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[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[1-[8-[4-[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]triazol-1-yl]octyl]triazol-4-yl]propanoate
Show/Hide
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C60H70Cl2F2N8O6
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1
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| 1 |
Ki = 19 nM
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CP0386862
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5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carbaldehyde
Show/Hide
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C23H28N4O3
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1
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| 1 |
Ki = 19 nM
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CP0481803
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1-[N-[(4-fluorophenyl)methyl]anilino]-3-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]urea
Show/Hide
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C25H30FN7O
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1
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| 1 |
Ki = 19 nM
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CP0104629
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(3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridin-6-yl)methanol
Show/Hide
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C19H21ClN4O
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2
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| 1 |
Ki = 19.5 nM
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| 2 |
Ki = 20 nM
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CP0453454
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N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclopentanecarbonylamino)-2-methoxybenzamide
Show/Hide
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C25H30ClN3O3
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1
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| 1 |
Ki = 20 nM
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CP0430153
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(7R,9aS)-7-(4-tert-Butyl-phenoxymethyl)-2-pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
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C23H32N4O
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1
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| 1 |
Ki = 20 nM
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CP0463689
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1-(1-benzylpyrrolidin-3-yl)-N-[[2-(5-bromo-2-methoxyphenyl)-1,3-oxazol-4-yl]methyl]methanamine
Show/Hide
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C23H26BrN3O2
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1
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| 1 |
Ki = 20 nM
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CP0436141
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1-(4-(1H-pyrazol-1-yl)benzyl)-4-phenylpiperazine
Show/Hide
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C20H22N4
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1
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| 1 |
Ki = 20 nM
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CP0411984
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4-[4-(2,5-Dimethylphenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
Show/Hide
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C23H28FNO2
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1
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| 1 |
Ki = 20 nM
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CP0489169
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1-[[1-(6-fluorohexyl)triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C20H30FN5O
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1
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| 1 |
Ki = 20 nM
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CP0380143
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4-bromo-N-[2-[4-[2-(1H-indol-3-yl)ethyl]piperazin-1-yl]ethyl]aniline
Show/Hide
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C22H27BrN4
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1
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| 1 |
Ki = 20 nM
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CP0438116
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1-(4-fluorophenyl)imino-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C21H26FN5O2
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1
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| 1 |
Ki = 20 nM
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CP0468089
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3-{2-[4-(4,5-Dimethyl-thiazol-2-yl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
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C19H24N4OS
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1
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| 1 |
Ki = 20.8 nM
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CP0895111
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1-(2-Methoxy-phenyl)-4-[4-(3-thiophen-2-yl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
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C22H28ClN3O2S
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1
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| 1 |
Ki = 21 nM
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CP0170565
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5-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrole-3-carbonitrile
Show/Hide
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C16H18N4
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1
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| 1 |
Ki = 21 nM
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CP0343243
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3-{[4-(3,4-Dichlorophenyl)piperazin-1-yl]methyl}-2,5,7-trimethylimidazo[1,2-c]pyrimidine
Show/Hide
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C20H23Cl2N5
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1
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| 1 |
Ki = 21 nM
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CP0405815
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[5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-2-yl]methanol
Show/Hide
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C23H30N4O3
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1
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| 1 |
Ki = 21 nM
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CP0536408
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1-(N-benzylanilino)-3-[3-[4-(4-iodophenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C27H32IN5O
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1
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| 1 |
Ki = 21 nM
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CP0407200
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3-[4-(3,4-Dichloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
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C20H18Cl2N4
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1
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| 1 |
Ki = 22 nM
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CP0393062
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N-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]-4-(2-phenylethynyl)benzamide
Show/Hide
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C27H25Cl2N3O
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1
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| 1 |
Ki = 22 nM
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CP0391025
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N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-3-methoxy-4-[3-[1-[8-[4-[3-[2-methoxy-4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]benzamide
Show/Hide
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C61H84N10O6
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1
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| 1 |
Ki = 22 nM
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CP0375872
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N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
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C23H30N4O
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1
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| 1 |
Ki = 22 nM
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CP0406477
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3-{2-[4-(4-Methyl-pyridin-2-yl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
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C20H24N4O
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1
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| 1 |
Ki = 22.6 nM
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CP0473734
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-2,5-dimethylbenzamide
Show/Hide
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C24H33N3O2
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1
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| 1 |
Ki = 23 nM
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CP0423154
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1-[[1-[2-(2-fluoroethoxy)ethyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C18H26FN5O2
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1
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| 1 |
Ki = 23 nM
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CP0829558
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5-cyano-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
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C25H29N5O2
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1
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| 1 |
Ki = 23.99 nM
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CP0141757
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N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]benzamide
Show/Hide
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C19H20N4O
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1
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| 1 |
Ki = 23.99 nM
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CP0396893
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(NE)-N-[[5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-2-yl]methylidene]hydroxylamine
Show/Hide
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C22H25Cl2N5O2
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1
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| 1 |
Ki = 24 nM
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CP0398765
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bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] butanedioate
Show/Hide
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C46H48Cl2F2N2O6
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1
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| 1 |
Ki = 24 nM
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CP0401624
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3-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-2,3-dihydro-isoindol-1-one
Show/Hide
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C20H23N3O
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1
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| 1 |
Ki = 24.5 nM
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CP0348803
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3-(4-Phenyl-piperidin-1-ylmethyl)-1H-indole
Show/Hide
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C20H22N2
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1
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| 1 |
Ki = 25 nM
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CP0342253
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3-Methyl-2-morpholin-4-yl-7-[(4-phenylpiperazin-1-yl)methyl]-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Show/Hide
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C22H28N6O2
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1
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| 1 |
Ki = 25 nM
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CP0033479
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(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Show/Hide
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C17H19ClN2S
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1
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| 1 |
Ki = 25.12 nM
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CP0453469
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7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-pyrazolo[1,5-a]pyridine
Show/Hide
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C30H35ClN6
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1
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| 1 |
Ki = 26 nM
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CP0077364
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3-(4-bromophenoxy)-N-[2-(4-methylphenoxy)ethyl]propan-1-amine
Show/Hide
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C18H22BrNO2
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1
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| 1 |
Ki = 27 nM
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CP0460372
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Biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide; oxalic acid
Show/Hide
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C28H33N3O2
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1
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| 1 |
Ki = 27 nM
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CP0439817
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5-(2-Benzylamino-ethoxy)-2-chloro-phenylamine
Show/Hide
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C15H17ClN2O
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1
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| 1 |
Ki = 27.2 nM
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CP0465331
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3-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
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C20H22ClN3O
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1
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| 1 |
Ki = 27.8 nM
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CP0899360
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1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-(2-ethoxy-phenyl)-piperazine hydrochloride
Show/Hide
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C27H36ClN3O4
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1
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| 1 |
Ki = 28 nM
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CP0877757
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4-(6-fluoropyridin-2-yl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}benzamide
Show/Hide
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C27H31FN4O2
|
1
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| 1 |
Ki = 28 nM
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CP0046178
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-[1-(4-nitrophenyl)triazol-4-yl]butanamide
Show/Hide
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C26H31Cl2N7O3
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1
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| 1 |
Ki = 28 nM
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CP0528966
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1-(N-benzylanilino)-3-[2-[4-(4-bromophenyl)piperazin-1-yl]ethyl]urea
Show/Hide
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C26H30BrN5O
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1
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| 1 |
Ki = 28 nM
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CP0401667
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
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C20H19ClN4
|
1
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| 1 |
Ki = 29 nM
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CP0439308
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-fluoro-phenyl)-pyrazolo[1,5-a]pyridine
Show/Hide
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C24H22ClFN4
|
1
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| 1 |
Ki = 29 nM
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CP0418145
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2-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
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C22H24Cl2N4O2
|
1
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| 1 |
Ki = 29 nM
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CP0385667
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[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[2-[[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]-methylamino]ethyl-methylamino]propanoate
Show/Hide
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C52H62Cl2F2N4O6
|
1
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| 1 |
Ki = 29 nM
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CP0395411
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(3-Phenoxy-propyl)-(2-p-tolylsulfanyl-ethyl)-amine
Show/Hide
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C18H23NOS
|
1
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| 1 |
Ki = 30 nM
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CP0472713
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4-[4-([2.2]Paracyclophan-4-yl)-4-hydroxypiperidin-1-yl]-1-([2.2]-paracyclophan-4-yl)butan-1-one
Show/Hide
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C41H45NO2
|
1
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| 1 |
Ki = 30 nM
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CP0473501
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1-(2,5-Dimethylphenyl)-4-[4-(2,5-dimethylphenyl)-4-hydroxypiperidin-1-yl]butan-1-one
Show/Hide
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C25H33NO2
|
1
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| 1 |
Ki = 30 nM
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CP0375873
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4-[3-(2-butyltriazol-4-yl)propoxy]-N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
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C32H47N5O3
|
1
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| 1 |
Ki = 30 nM
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CP0431629
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4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(3R)-6-ethynyl-3,4-dihydro-2H-pyran-3-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
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C31H45N5O4
|
1
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| 1 |
Ki = 30 nM
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CP0405813
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4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-(3-formylpyrazolo[1,5-a]pyridin-5-yl)butanamide
Show/Hide
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C22H23Cl2N5O2
|
1
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| 1 |
Ki = 30 nM
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CP0045037
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Benzofuran-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
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C24H29N3O3
|
1
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| 1 |
Ki = 30.2 nM
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CP0171882
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N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
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C21H25N5O2
|
1
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| 1 |
Ki = 30.2 nM
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CP0800232
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5-ethynyl-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide
Show/Hide
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C26H29N3O2S
|
1
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| 1 |
Ki = 30.9 nM
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CP0311650
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N-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]benzamide
Show/Hide
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C19H23N3O2
|
1
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| 1 |
Ki = 30.9 nM
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CP0440449
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5-Iodo-thiophene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
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C20H26IN3O2S
|
1
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| 1 |
Ki = 31 nM
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CP0388832
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1-(3,4-difluorophenyl)imino-3-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]urea
Show/Hide
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C23H28F2N4O
|
1
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| 1 |
Ki = 31 nM
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CP0412994
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4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-[3-[(Z)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]butanamide
Show/Hide
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C22H24Cl2N6O2
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1
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| 1 |
Ki = 31 nM
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CP0446909
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8-hydroxy-5-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]-1H-quinolin-2-one
Show/Hide
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C24H27N5O3
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1
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| 1 |
Ki = 31 nM
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CP0290176
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(S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbaldehyde
Show/Hide
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C15H24N2O
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2
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| 1 |
Ki = 32 nM
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| 2 |
Ki = 2500 nM
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CP0423153
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(2R,3S,4S,5R)-5-fluoro-2-(hydroxymethyl)-6-[3-[4-[4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]triazol-1-yl]phenoxy]propoxy]oxane-3,4-diol
Show/Hide
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C29H38FN5O7
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1
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| 1 |
Ki = 32 nM
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CP0405820
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N-(3-cyanopyrazolo[1,5-a]pyridin-5-yl)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butanamide
Show/Hide
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C22H22Cl2N6O
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1
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| 1 |
Ki = 32 nM
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CP0454831
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N-[2-(4-chlorophenyl)sulfanylethyl]-3-phenoxypropan-1-amine
Show/Hide
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C17H20ClNOS
|
1
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| 1 |
Ki = 33 nM
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CP0900185
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1-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-butyl}-4-(2-methoxy-phenyl)-piperazine hydrochloride
Show/Hide
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C24H29ClFN3O2
|
1
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| 1 |
Ki = 33 nM
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CP0446059
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N-[4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
Show/Hide
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C32H38ClN3O2
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1
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| 1 |
Ki = 33 nM
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CP0380807
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2-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H24Cl2N4O
|
1
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| 1 |
Ki = 33 nM
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CP0412174
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[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[4-[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]piperazin-1-yl]propanoate
Show/Hide
|
C52H60Cl2F2N4O6
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1
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| 1 |
Ki = 33 nM
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CP0489217
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bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] pentanedioate
Show/Hide
|
C47H50Cl2F2N2O6
|
1
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| 1 |
Ki = 33 nM
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CP0468620
|
1-[4-methoxy-N-[(3-methoxyphenyl)methyl]anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
|
C30H39N5O4
|
1
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| 1 |
Ki = 33 nM
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CP0879266
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1-{4-[3-(2,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-(2-methoxy-phenyl)-piperazine hydrochloride
Show/Hide
|
C26H34ClN3O4
|
1
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| 1 |
Ki = 34 nM
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CP0915789
|
1-(2-Ethoxy-phenyl)-4-[4-(3-phenyl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
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C25H32ClN3O2
|
1
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| 1 |
Ki = 34 nM
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CP0881177
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4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}benzamide
Show/Hide
|
C27H31FN4O2
|
1
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| 1 |
Ki = 34 nM
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CP0439421
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4-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide
Show/Hide
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C22H28FN3O2
|
1
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| 1 |
Ki = 34 nM
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CP0400542
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N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-4-[3-[1-[8-[4-[3-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butylcarbamoyl]-2-methoxyphenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]-3-methoxybenzamide
Show/Hide
|
C66H92N10O6
|
1
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| 1 |
Ki = 34 nM
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CP0382046
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1-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-3-(4-fluorophenyl)iminourea
Show/Hide
|
C23H29FN4O
|
1
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| 1 |
Ki = 34 nM
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CP0405821
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N-(3-formylpyrazolo[1,5-a]pyridin-5-yl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butanamide
Show/Hide
|
C23H27N5O3
|
1
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| 1 |
Ki = 34 nM
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CP0400130
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N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-3-(2-phenylethynyl)benzamide
Show/Hide
|
C31H35N3O2
|
1
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| 1 |
Ki = 35 nM
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CP0380809
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[5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-2-yl]methanol
Show/Hide
|
C22H26Cl2N4O2
|
1
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| 1 |
Ki = 35 nM
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CP0468090
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3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2-methyl-2,3-dihydro-isoindol-1-one
Show/Hide
|
C23H29N3O
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1
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| 1 |
Ki = 35.1 nM
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CP0381530
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1-(3,4-difluorophenyl)imino-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]urea
Show/Hide
|
C22H27F2N5O2
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1
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| 1 |
Ki = 36 nM
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CP0468618
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1-(4-fluorophenyl)imino-3-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]urea
Show/Hide
|
C20H24FN5O2
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1
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| 1 |
Ki = 36 nM
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CP0165177
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Benzyl-(2-trifluoromethyl-3,6,7,8-tetrahydro-chromeno[7,8-d]imidazol-8-ylmethyl)-amine
Show/Hide
|
C19H18F3N3O
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1
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| 1 |
Ki = 37 nM
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CP0430726
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-2-methyl-7-phenyl-pyrazolo[1,5-a]pyridine
Show/Hide
|
C25H25ClN4
|
1
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| 1 |
Ki = 37 nM
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CP0378975
|
N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C23H30N4O
|
1
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| 1 |
Ki = 37 nM
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CP0434990
|
5-[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C23H27N7O
|
1
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| 1 |
Ki = 37 nM
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CP0438498
|
3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
|
C21H25N3O2
|
1
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| 1 |
Ki = 37.3 nM
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CP0159468
|
3-(4-bromophenoxy)-N-[2-(4-chlorophenoxy)ethyl]propan-1-amine
Show/Hide
|
C17H19BrClNO2
|
1
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| 1 |
Ki = 38 nM
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CP0382586
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3-[2-[2-[2-[2-[3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]benzamide
Show/Hide
|
C50H68N6O9
|
1
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| 1 |
Ki = 38 nM
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CP0399133
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4-[2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C26H31NO4
|
1
|
| 1 |
Ki = 38 nM
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CP0071762
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C26H31N3O2
|
2
|
| 1 |
Ki = 38.9 nM
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| 2 |
Ki = 44 nM
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CP0403715
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(7R,9aR)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C19H22F2N4O
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1
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| 1 |
Ki = 39 nM
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CP0520154
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((R)-1-Benzyl-pyrrolidin-3-yl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-amine
Show/Hide
|
C22H24BrN3O2
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1
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| 1 |
Ki = 39 nM
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CP0276665
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3-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,7-dimethylimidazo[1,2-c]pyrimidine
Show/Hide
|
C20H25N5O
|
1
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| 1 |
Ki = 39 nM
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CP0374992
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4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-1-([2.2]paracyclophan-4-yl)butan-1-one
Show/Hide
|
C31H34ClNO2
|
1
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| 1 |
Ki = 39 nM
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CP0373714
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6-Methyl-5,6,7,8,13,15-hexahydro-4H-indolo[4,3a,3-fg][3]benzazacycloundecene
Show/Hide
|
C20H22N2
|
1
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| 1 |
Ki = 39.1 nM
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CP0179734
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1-[(2-bromophenyl)methyl]-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-5-propyltriazole-4-carboxamide
Show/Hide
|
C29H39BrN6O2
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1
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| 1 |
Ki = 39.81 nM
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CP0717114
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6-cyano-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
|
C25H29N5O2
|
1
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| 1 |
Ki = 39.81 nM
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CP0373474
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-3-ethynylbenzamide
Show/Hide
|
C23H25Cl2N3O
|
1
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| 1 |
Ki = 40 nM
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CP0399842
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(S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbonitrile
Show/Hide
|
C15H23N3
|
2
|
| 1 |
Ki = 40 nM
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| 2 |
Ki = 9700 nM
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CP0440817
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4-[3-[1-[8-[4-[3-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butylcarbamoyl]-2-methoxyphenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]-3-methoxy-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C65H91N11O7
|
1
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| 1 |
Ki = 40 nM
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CP0376123
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1-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-3-(3,4,5-trifluorophenyl)iminourea
Show/Hide
|
C23H27F3N4O
|
1
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| 1 |
Ki = 40 nM
|
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CP0089965
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
Ki = 40.74 nM
|
|
|
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CP0380811
|
4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
Ki = 41 nM
|
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CP0385662
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bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] hexanedioate
Show/Hide
|
C48H52Cl2F2N2O6
|
1
|
| 1 |
Ki = 41 nM
|
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CP0483373
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[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[1-[2-[2-[2-[2-[4-[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]propanoate
Show/Hide
|
C60H70Cl2F2N8O9
|
1
|
| 1 |
Ki = 41 nM
|
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CP0408435
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5-[4-[4-(8-hydroxy-2-oxo-1H-quinolin-5-yl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C25H27N5O4
|
1
|
| 1 |
Ki = 41 nM
|
|
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CP0171884
|
1-[(2-bromophenyl)methyl]-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C27H35BrN6O2
|
1
|
| 1 |
Ki = 41.69 nM
|
|
|
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CP0378054
|
(R)-3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethyl}-2,3-dihydro-isoindol-1-one
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 42 nM
|
|
|
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CP0440446
|
5-Iodo-benzo[b]thiophene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C24H28IN3O2S
|
1
|
| 1 |
Ki = 42 nM
|
|
|
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CP0400546
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-3-methoxybenzamide
Show/Hide
|
C33H47N5O3
|
1
|
| 1 |
Ki = 42 nM
|
|
|
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CP0413704
|
5-[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C22H23Cl2N7
|
1
|
| 1 |
Ki = 42 nM
|
|
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CP0374901
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3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
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C24H30FN3O2
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1
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| 1 |
Ki = 43 nM
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CP0040242
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16-methoxy-11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(18),3(8),4,6,14,16-hexaene
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C19H23NO
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1
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| 1 |
Ki = 43.4 nM
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CP0449394
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2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
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C18H19FN4
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1
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| 1 |
Ki = 44 nM
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CP0436097
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-fluorobenzamide
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C21H24Cl2FN3O
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1
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| 1 |
Ki = 44 nM
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CP0468621
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1-(N-benzylanilino)-3-[2-[4-(4-iodophenyl)piperazin-1-yl]ethyl]urea
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C26H30IN5O
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1
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| 1 |
Ki = 44 nM
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CP0805511
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5-cyano-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide
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C25H28N4O2S
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1
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| 1 |
Ki = 44.67 nM
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CP0373604
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1-(2,5-Dimethylphenyl)-4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butan-1-one
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C25H33NO
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1
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| 1 |
Ki = 45 nM
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CP0385451
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5-(2-ethoxyethoxymethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide
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C27H37N5O4
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1
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| 1 |
Ki = 45 nM
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CP0197217
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5-Iodo-benzofuran-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
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C24H28IN3O3
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1
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| 1 |
Ki = 46 nM
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CP0496624
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2-[5-[4-(4-Chlorophenyl)piperazin-1-yl]pentyl]pyrazolo[1,5-a]-pyridine
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C22H27ClN4
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1
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| 1 |
Ki = 46 nM
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CP0489220
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[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[1-[2-[2-[2-[2-[2-[4-[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]propanoate
Show/Hide
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C62H74Cl2F2N8O10
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1
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| 1 |
Ki = 46 nM
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CP0481804
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1-[3-[4-(4-bromophenyl)piperazin-1-yl]propyl]-3-[N-[(4-fluorophenyl)methyl]anilino]urea
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C27H31BrFN5O
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1
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| 1 |
Ki = 46 nM
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CP0460411
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4-(4-Benzyl-piperazin-1-yl)-1H-benzoimidazole
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C18H20N4
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1
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| 1 |
Ki = 47 nM
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CP0087394
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N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-1-(4-nitrophenyl)triazole-4-carboxamide
Show/Hide
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C22H25N7O4
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1
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| 1 |
Ki = 47 nM
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CP0380813
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ethyl 5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carboxylate
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C24H28Cl2N4O3
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1
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| 1 |
Ki = 47 nM
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CP0381532
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1-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-(3,4,5-trifluorophenyl)iminourea
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C22H26F3N5O2
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1
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| 1 |
Ki = 47 nM
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CP0409085
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((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine
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C18H29NO
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1
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| 1 |
Ki = 48 nM
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CP0372552
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-[2-[2-[2-[2-[3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]benzamide
Show/Hide
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C52H72N6O9
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1
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| 1 |
Ki = 48 nM
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CP0072419
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(SNAP-8719)[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone
Show/Hide
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C22H28F3N3O2
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1
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| 1 |
Ki = 49 nM
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CP0536028
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4-(2-Phenyl-3H-imidazol-4-ylmethyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl
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C18H20N6
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1
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| 1 |
Ki = 50 nM
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CP0850057
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(2H-Benzo[1,4]oxazin-3-yl)-[5-(4-pyridin-2-yl-piperazin-1-yl)-pentyl]-amine; compound with but-2-enedioic acid
Show/Hide
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C26H33N5O5
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1
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| 1 |
Ki = 50 nM
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CP0451179
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3-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole-5-carbonitrile
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C20H20N4
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1
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| 1 |
Ki = 50 nM
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CP0420836
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3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4-methyl-pyrazolo[1,5-a]pyridine
Show/Hide
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C19H21ClN4
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1
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| 1 |
Ki = 50 nM
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CP0869072
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1-(2-Methoxy-phenyl)-4-{4-[3-(3-nitro-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
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C24H29ClN4O4
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1
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| 1 |
Ki = 50 nM
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CP0080177
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4-bromo-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
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C22H28BrN3O2
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1
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| 1 |
Ki = 50.12 nM
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CP0056386
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5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one
Show/Hide
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C21H21ClN4OS
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1
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| 1 |
Ki = 50.12 nM
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CP0874524
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1-(2-Ethoxy-phenyl)-4-{4-[3-(3-nitro-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
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C25H31ClN4O4
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1
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| 1 |
Ki = 51 nM
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CP0431087
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-[2-[2-[2-[2-[3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]pyrazolo[1,5-a]pyridin-5-yl]oxyethoxy]ethoxy]ethoxy]ethoxy]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
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C52H68N10O9
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1
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| 1 |
Ki = 51 nM
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CP0198140
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2-(1H-benzimidazol-4-yloxy)-N-benzylethanamine
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C16H17N3O
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1
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| 1 |
Ki = 51.6 nM
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CP0859228
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(2H-Benzo[1,4]oxazin-3-yl)-[5-(4-phenyl-piperazin-1-yl)-pentyl]-amine hydrobromide
Show/Hide
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C23H31BrN4O
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1
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| 1 |
Ki = 52 nM
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CP0467945
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(1-Benzyl-piperidin-4-yl)-(2-phenyl-thiazol-4-ylmethyl)-amine
Show/Hide
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C22H25N3S
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1
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| 1 |
Ki = 53 nM
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CP0405798
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(6R)-6-[propyl(4-pyrazolo[1,5-a]pyridin-6-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
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C24H31N3O2
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1
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| 1 |
Ki = 54 nM
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CP0429840
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((6S,7R)-6-Methyl-6,7,8,9-tetrahydro-naphtho[1,2-b]furan-7-yl)-dipropyl-amine
Show/Hide
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C19H27NO
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1
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| 1 |
Ki = 55 nM
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CP0401110
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5-hydroxy-8-[2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C28H32N2O5
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1
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| 1 |
Ki = 55 nM
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CP0393922
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5-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]quinolin-8-ol
Show/Hide
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C24H27N5O2
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1
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| 1 |
Ki = 55 nM
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CP0380814
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5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
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C22H24Cl2N4O2
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1
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| 1 |
Ki = 57 nM
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CP0042927
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7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
Show/Hide
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C23H27Cl2N3O2
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4
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| 1 |
Ki = 57.54 nM
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| 2 |
Ki = 63 nM
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| 3 |
Ki = 81 nM
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| 4 |
Ki = 100 nM
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CP0711087
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5-cyano-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
Show/Hide
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C25H28N4O3
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1
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| 1 |
Ki = 57.54 nM
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CP0869075
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1-(2-Fluoro-phenyl)-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
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C25H29ClFN3O
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1
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| 1 |
Ki = 58 nM
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CP0051912
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(5S)-N,N-dipropyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-amine
Show/Hide
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C13H23N3
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3
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| 1 |
Ki = 58 nM
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| 2 |
Ki = 380 nM
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| 3 |
Ki = 1700 nM
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CP0295825
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N,N-dipropyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-amine
Show/Hide
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C13H23N3
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2
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| 1 |
Ki = 58 nM
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| 2 |
Ki = 1600 nM
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CP0899288
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rac-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-amino-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine
Show/Hide
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C27H34N4O
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1
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| 1 |
Ki = 59 nM
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CP0375613
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4-[3-(2-butyltriazol-4-yl)propoxy]-N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
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C32H47N5O3
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1
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| 1 |
Ki = 59 nM
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CP0408434
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5-hydroxy-8-(4-methylpiperazin-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
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C13H17N3O3
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1
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| 1 |
Ki = 59 nM
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CP0509639
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3-[4-(3-Chloro-4-hydroxymethyl-phenyl)-piperazin-1-yl]-1-(4-chloro-phenyl)-propan-1-one
Show/Hide
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C20H22Cl2N2O2
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1
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| 1 |
Ki = 60 nM
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CP0472405
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5-hydroxy-8-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]-1,4-diazepan-1-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H32N4O5
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1
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| 1 |
Ki = 60 nM
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CP0207464
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7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene-3-ol
Show/Hide
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C19H23NO
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1
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| 1 |
Ki = 60.15 nM
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CP0377118
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4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(2,5-dimethylphenyl)butan-1-one
Show/Hide
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C23H28ClNO2
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1
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| 1 |
Ki = 61 nM
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CP0550960
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1-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-3-(4-methoxy-N-prop-2-enylanilino)urea
Show/Hide
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C25H35N5O3
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1
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| 1 |
Ki = 61 nM
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CP0169492
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Benzyl-[2-(2-methyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine
Show/Hide
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C17H19N3O
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1
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| 1 |
Ki = 61.1 nM
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CP0405997
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6-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
Show/Hide
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C19H20ClN3O2
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1
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| 1 |
Ki = 62.4 nM
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CP0392597
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1-Benzyl-4-(2-oxazol-5-yl-pyrrol-1-yl)-piperidine
Show/Hide
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C19H21N3O
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1
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| 1 |
Ki = 63 nM
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CP0467497
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5-(2-ethoxyethoxy)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
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C27H37N5O4
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1
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| 1 |
Ki = 64 nM
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CP0482775
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1-[4-methoxy-N-(2-methylprop-2-enyl)anilino]-3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]urea
Show/Hide
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C26H37N5O3
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1
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| 1 |
Ki = 64 nM
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CP0431322
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(12S)-11,12-dimethyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaene
Show/Hide
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C21H24N2
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1
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| 1 |
Ki = 64.1 nM
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CP0375779
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N-[4-[4-(2-methylsulfanylphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
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C23H29N5OS
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1
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| 1 |
Ki = 65 nM
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CP0135428
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3-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-5,7-dimethylimidazo[1,2-c]pyrimidine
Show/Hide
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C20H25N5O
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1
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| 1 |
Ki = 66 nM
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CP0342252
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3-{[4-(4-Chlorophenyl)piperazin-1-yl]methyl}-2,5,7-trimethylimidazo[1,2-c]pyrimidine
Show/Hide
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C20H24ClN5
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1
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| 1 |
Ki = 66 nM
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CP0458292
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8-hydroxy-5-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]piperazin-1-yl]-1H-quinolin-2-one
Show/Hide
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C26H30N4O4
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1
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| 1 |
Ki = 66 nM
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CP0097278
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-5-carboxamide
Show/Hide
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C23H29N5O2
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1
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| 1 |
Ki = 67.61 nM
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CP0190893
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N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
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C24H31N5O2
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1
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| 1 |
Ki = 67.61 nM
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CP0465035
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-[2-[2-[2-[2-[[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
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C54H76N6O9
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1
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| 1 |
Ki = 68 nM
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CP0393061
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N-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-4-ethynylbenzamide
Show/Hide
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C24H27Cl2N3O
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1
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| 1 |
Ki = 69 nM
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CP0398431
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4-phenyl-N-[4-[propyl-[4-(2-trimethylsilylethynyl)cyclohex-3-en-1-yl]amino]butyl]benzamide
Show/Hide
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C31H42N2OSi
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1
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| 1 |
Ki = 69 nM
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CP0167459
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2,5,7-Trimethyl-3-[4-(phenylpiperazin-1-yl)methyl]imidazo[1,2-c]pyrimidine
Show/Hide
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C20H25N5
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1
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| 1 |
Ki = 70 nM
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CP0393637
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5-(2-ethoxyethoxy)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
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C26H35N5O4
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1
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| 1 |
Ki = 70 nM
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CP0404616
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1-(2-Phenyl-3H-imidazol-4-ylmethyl)-4-pyridin-3-yl-piperazine
Show/Hide
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C19H21N5
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1
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| 1 |
Ki = 73 nM
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CP0059541
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(3-Phenoxy-propyl)-(2-o-tolyloxy-ethyl)-amine
Show/Hide
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C18H23NO2
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1
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| 1 |
Ki = 74 nM
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CP0446908
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8-hydroxy-5-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]-1,4-diazepan-1-yl]-1H-quinolin-2-one
Show/Hide
|
C27H32N4O4
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1
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| 1 |
Ki = 75 nM
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CP0171883
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1-[(2-bromophenyl)methyl]-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-propyltriazole-4-carboxamide
Show/Hide
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C28H37BrN6O2
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1
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| 1 |
Ki = 75.86 nM
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CP0885775
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1-{4-[3-(2,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-phenyl-piperazine hydrochloride
Show/Hide
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C25H32ClN3O3
|
1
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| 1 |
Ki = 76 nM
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CP0378942
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6-Fluoro-pyridine-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C21H27FN4O2
|
1
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| 1 |
Ki = 76 nM
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CP0444166
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5-[4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C23H25Cl2N7
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1
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| 1 |
Ki = 76 nM
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CP0078330
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7-[4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H29Cl2N3O2
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1
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| 1 |
Ki = 76 nM
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CP0382590
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-[2-[2-[2-[2-[3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]pyrazolo[1,5-a]pyridin-5-yl]oxyethoxy]ethoxy]ethoxy]ethoxy]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C54H72N10O9
|
1
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| 1 |
Ki = 77 nM
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CP0171880
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N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C24H31N5O2
|
1
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| 1 |
Ki = 77.62 nM
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CP0382591
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-[2-[2-[2-[2-[2-[[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
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C56H80N6O10
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1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0380815
|
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0422364
|
3-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-2-methyl-2,3-dihydro-isoindol-1-one
Show/Hide
|
C21H24ClN3O
|
1
|
| 1 |
Ki = 78.6 nM
|
|
|
|
CP0466838
|
2-(4-(4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)butyl)isoindoline-1,3-dione
Show/Hide
|
C25H24FN3O2
|
1
|
| 1 |
Ki = 79.43 nM
|
|
|
|
CP0297087
|
3-(2-Benzylamino-ethoxy)-phenol
Show/Hide
|
C15H17NO2
|
1
|
| 1 |
Ki = 80.6 nM
|
|
|
|
CP0529336
|
(R)-3-[4-(3-Chloro-4-hydroxymethyl-phenyl)-piperazin-1-yl]-1-(4-chloro-phenyl)-propan-1-ol
Show/Hide
|
C20H24Cl2N2O2
|
1
|
| 1 |
Ki = 81.4 nM
|
|
|
|
CP0372555
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4-[2-[2-[2-[2-[[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C52H72N6O9
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0082575
|
1-Phenyl-4-(4-phenylethynyl-1H-pyrrol-2-ylmethyl)-piperazine
Show/Hide
|
C23H23N3
|
1
|
| 1 |
Ki = 83 nM
|
|
|
|
CP0394874
|
4-[3-(1-butyltriazol-4-yl)propoxy]-3-methoxy-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C32H46N6O4
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0387634
|
(6R)-6-[propyl(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0489974
|
4-Benzoylamino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide
Show/Hide
|
C26H26ClN3O3
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0442588
|
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-(4-fluoro-phenyl)-2-methyl-pyrazolo[1,5-a]pyridine
Show/Hide
|
C25H24ClFN4
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0125988
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-4-carboxamide
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
Ki = 87.1 nM
|
|
|
|
CP0914731
|
1-(2-Methoxy-phenyl)-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C26H32ClN3O2
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0380804
|
5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-2-carbaldehyde
Show/Hide
|
C22H24Cl2N4O2
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0489219
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 3-[1-[10-[4-[3-[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]oxy-3-oxopropyl]triazol-1-yl]decyl]triazol-4-yl]propanoate
Show/Hide
|
C62H74Cl2F2N8O6
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0160175
|
1-[(2-bromophenyl)methyl]-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C26H33BrN6O2
|
1
|
| 1 |
Ki = 91.2 nM
|
|
|
|
CP0401301
|
4-(4-Benzyl-piperazin-1-yl)-phenol
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
Ki = 91.8 nM
|
|
|
|
CP0041389
|
Benzofuran-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H25Cl2N3O2
|
1
|
| 1 |
Ki = 93.33 nM
|
|
|
|
CP0498116
|
Benzyl-(2-phenoxy-ethyl)-amine
Show/Hide
|
C15H17NO
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0381816
|
1-(4-fluorophenyl)imino-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]urea
Show/Hide
|
C22H28FN5O2
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0393917
|
7-[4-[4-(8-hydroxyquinolin-5-yl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0902338
|
1-{4-[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-butyl}-4-phenyl-piperazine hydrochloride
Show/Hide
|
C23H27ClFN3O
|
1
|
| 1 |
Ki = 96 nM
|
|
|
|
CP0393147
|
6-Fluoro-pyridine-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C20H23Cl2FN4O
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0413703
|
5-[4-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C23H25N7O2
|
1
|
| 1 |
Ki = 98 nM
|
|
|
|
CP0183661
|
1-Phenyl-4-(1H-pyrrol-2-ylmethyl)-piperazine
Show/Hide
|
C15H19N3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0393063
|
N-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-3-ethynylbenzamide
Show/Hide
|
C24H27Cl2N3O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0389513
|
N-[4-(4-methyltriazol-1-yl)butyl]-N-propyl-4-prop-1-ynylcyclohex-3-en-1-amine
Show/Hide
|
C19H30N4
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0441826
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-6-fluoropyridine-3-carboxamide
Show/Hide
|
C20H23Cl2FN4O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0428642
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-[2-[2-[2-[2-[[3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]pyrazolo[1,5-a]pyridin-5-yl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C56H76N10O9
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0433010
|
1-[[1-[4-[2-[2-(2-fluoroethoxy)ethoxy]ethoxy]phenyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C26H34FN5O4
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0496816
|
(7S,9aR)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-pyrimidin-2-yl)-octahydro-pyrido[1,2-a]pyrazine
Show/Hide
|
C19H22F2N4O
|
1
|
| 1 |
Ki = 106 nM
|
|
|
|
CP0896993
|
(2H-Benzo[1,4]oxazin-3-yl)-[3-(4-pyrimidin-2-yl-piperazin-1-yl)-propyl]-amine; compound with but-2-enedioic acid
Show/Hide
|
C23H28N6O5
|
1
|
| 1 |
Ki = 107 nM
|
|
|
|
CP0110876
|
N-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]benzamide
Show/Hide
|
C18H20ClN3O
|
1
|
| 1 |
Ki = 107.15 nM
|
|
|
|
CP0376374
|
N-[(3S)-1-benzylpyrrolidin-3-yl]-5-chloro-4-(cyclohexanecarbonylamino)-2-methoxybenzamide
Show/Hide
|
C26H32ClN3O3
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0449027
|
3-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-indole-5-carbonitrile
Show/Hide
|
C20H19FN4
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0405399
|
[3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]pyrazolo[1,5-a]pyridin-4-yl]methanol
Show/Hide
|
C19H21ClN4O
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0393060
|
4-ethynyl-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C24H29N3O2
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0407055
|
N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0118796
|
Cariprazine
Show/Hide
|
C21H32Cl2N4O
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0428506
|
(R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid
Show/Hide
|
C17H19NO2
|
1
|
| 1 |
Ki = 116 nM
|
|
|
|
CP0859683
|
1-Phenyl-4-[4-(3-thiophen-2-yl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C21H26ClN3OS
|
1
|
| 1 |
Ki = 117 nM
|
|
|
|
CP0395092
|
(R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-tetrahydro-1H-[1,3]diazepine
Show/Hide
|
C21H26N4
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0394273
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-ethynylbenzamide
Show/Hide
|
C23H25Cl2N3O
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0499699
|
2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(piperidin-1-yl)imidazo[1,2-b]pyridazine
Show/Hide
|
C22H26Cl2N6
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0433429
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
Show/Hide
|
C31H35Cl2N3O
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0343244
|
2,5,7-Trimethyl-3-[4-(2-pyridin-2-ylpiperazin-1-yl)methyl]imidazo[1,2-c]pyrimidine
Show/Hide
|
C19H24N6
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0373606
|
4-[4-(4-Chlorophenyl)piperazin-1-yl]-1-([2.2]paracyclophan-4-yl)butan-1-one
Show/Hide
|
C30H33ClN2O
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0373623
|
4-[4-([2.2]Paracyclophan-4-yl)piperazin-1-yl]-1-(4-fluorophenyl)-butan-1-one
Show/Hide
|
C30H33FN2O
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0885658
|
(2H-Benzo[1,4]oxazin-3-yl)-[5-(4-quinolin-2-yl-piperazin-1-yl)-pentyl]-amine hydrobromide
Show/Hide
|
C26H32BrN5O
|
1
|
| 1 |
Ki = 125 nM
|
|
|
|
CP0437589
|
2-{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethylene}-malononitrile
Show/Hide
|
C19H18ClN5
|
1
|
| 1 |
Ki = 125 nM
|
|
|
|
CP0409562
|
4-((7R,9aS)-2-Pyrimidin-2-yl-octahydro-pyrido[1,2-a]pyrazin-7-ylmethoxy)-benzoic acid methyl ester
Show/Hide
|
C21H26N4O3
|
1
|
| 1 |
Ki = 127 nM
|
|
|
|
CP0045034
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C23H29N5O2
|
3
|
| 1 |
Ki = 128.82 nM
|
|
|
| 2 |
Ki = 130 nM
|
|
|
| 3 |
Ki = 150 nM
|
|
|
|
CP0172631
|
1-[(4-methoxyphenyl)methyl]-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-propyltriazole-4-carboxamide
Show/Hide
|
C29H40N6O3
|
1
|
| 1 |
Ki = 128.82 nM
|
|
|
|
CP0454824
|
1-Benzyl-4-(3-oxazol-5-yl-pyrrol-1-yl)-piperidine
Show/Hide
|
C19H21N3O
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0432880
|
5-Iodo-thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C19H22Cl2IN3OS
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0432598
|
6-Fluoro-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-nicotinamide
Show/Hide
|
C21H27FN4O2
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0428646
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-[2-[2-[2-[2-[2-[2-[[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C58H84N6O11
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0380805
|
5-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H24Cl2N4O
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0385666
|
[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] 4-methylbenzoate
Show/Hide
|
C29H29ClFNO3
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0413701
|
5-[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C23H23Cl2N7O
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0437282
|
5-[4-[4-(5-hydroxy-2,3-dihydro-1,4-benzodioxin-8-yl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C24H28N4O5
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0480414
|
N-[2-chloro-5-[2-(thiophen-2-ylmethylamino)ethoxy]phenyl]methanesulfonamide
Show/Hide
|
C14H17ClN2O3S2
|
1
|
| 1 |
Ki = 137 nM
|
|
|
|
CP0378762
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-12-oxatetracyclo[8.5.2.24,7.011,15]nonadeca-1(15),4,6,10,13,16,18-heptaene-13-carboxamide
Show/Hide
|
C34H39N3O3
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0372556
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-[2-[2-[2-[2-[[3-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]pyrazolo[1,5-a]pyridin-5-yl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C54H72N10O9
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0393676
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-[2-[2-[2-[2-[2-[2-[2-[2-[[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C62H92N6O13
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0467632
|
3-(2-ethoxyethoxy)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]benzamide
Show/Hide
|
C25H35N3O4
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0384600
|
4-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0162854
|
(+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C16H25NO
|
1
|
| 1 |
Ki = 148 nM
|
|
|
|
CP0382976
|
2-(1-benzylpyrrolidin-3-yl)-N-[[2-(5-bromo-2-methoxyphenyl)-1,3-oxazol-4-yl]methyl]ethanamine
Show/Hide
|
C24H28BrN3O2
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0383910
|
1-(1-benzylpyrrolidin-3-yl)-N-[[2-(5-bromo-2-methoxyphenyl)-1,3-thiazol-4-yl]methyl]methanamine
Show/Hide
|
C23H26BrN3OS
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0461940
|
1-[[1-[2-[2-(2-fluoroethoxy)ethoxy]ethyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C20H30FN5O3
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0717116
|
6-ethynyl-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide
Show/Hide
|
C26H29N3O2S
|
1
|
| 1 |
Ki = 151.36 nM
|
|
|
|
CP0311605
|
1-benzyl-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C27H36N6O2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0393315
|
2-[3-(4-Phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethylene]-malononitrile
Show/Hide
|
C19H19N5
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0382589
|
5-(2-ethoxyethoxymethyl)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C28H39N5O4
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0428645
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4-[2-[2-[2-[2-[2-[2-[[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C56H80N6O11
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0463611
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] icosanedioate
Show/Hide
|
C62H80Cl2F2N2O6
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0393921
|
8-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]-2,3-dihydro-1,4-benzodioxin-5-ol
Show/Hide
|
C23H28N4O4
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0417490
|
N-[4-[4-[2-(2-fluoroethoxy)phenyl]piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C24H30FN5O2
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0894622
|
(2H-Benzo[1,4]oxazin-3-yl)-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-amine; compound with but-2-enedioic acid
Show/Hide
|
C24H30N6O5
|
1
|
| 1 |
Ki = 161 nM
|
|
|
|
CP0682498
|
N-(4-(4-(2-chlorophenyl)piperazin-1-yl)butyl)-3,4-dimethoxybenzamide
Show/Hide
|
C23H30ClN3O3
|
1
|
| 1 |
Ki = 169.82 nM
|
|
|
|
CP0391933
|
2-[(3R)-1-benzylpyrrolidin-3-yl]-N-[[2-(5-bromo-2-methoxyphenyl)-1,3-oxazol-4-yl]methyl]ethanamine
Show/Hide
|
C24H28BrN3O2
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0463625
|
((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(5-bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-amine
Show/Hide
|
C23H26BrN3OS
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0400133
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3-(2-phenylethynyl)benzamide
Show/Hide
|
C30H33N3O2
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0488819
|
N-[4-[4-(5-tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
Show/Hide
|
C41H47N3O
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0845762
|
[11C]-3-(2-oxo-3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)imidazolidin-1-yl)benzonitrile
Show/Hide
|
C18H21F3N4O
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0403324
|
7-(4-Benzyl-piperazin-1-yl)-3-[4-(4-chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[1,5-a]pyridine
Show/Hide
|
C29H33ClN6
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0406354
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(3S)-6-ethynyl-3,4-dihydro-2H-pyran-3-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C31H45N5O4
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0413700
|
5-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H21Cl2N7
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0915334
|
(2H-Benzo[1,4]oxazin-3-yl)-[4-(4-phenyl-piperazin-1-yl)-butyl]-amine; compound with but-2-enedioic acid
Show/Hide
|
C26H32N4O5
|
1
|
| 1 |
Ki = 188 nM
|
|
|
|
CP0373346
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-3-(2-phenylethynyl)benzamide
Show/Hide
|
C29H29Cl2N3O
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0389512
|
4-ethynyl-N-[4-[4-(4-phenylphenyl)triazol-1-yl]butyl]-N-propylcyclohex-3-en-1-amine
Show/Hide
|
C29H34N4
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0442092
|
N-[4-[(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C27H33ClN4O
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0393636
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4-[2-[2-[2-[2-[2-[[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C54H76N6O10
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0458293
|
8-hydroxy-5-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)-1,4-diazepan-1-yl]-1H-quinolin-2-one
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0905327
|
1-(2-Methoxy-phenyl)-4-[4-(3-phenyl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C24H30ClN3O2
|
1
|
| 1 |
Ki = 198 nM
|
|
|
|
CP0160210
|
N-[4-[4-(2-chlorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H28ClN3O
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0422264
|
1-(1-Benzyl-piperidin-4-yl)-1H-pyrrole-2-carbaldehyde
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0051933
|
(3-Chloro-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridin-5-yl)-dipropyl-amine
Show/Hide
|
C13H22ClN3
|
2
|
| 1 |
Ki = 200 nM
|
|
|
| 2 |
Ki = 6400 nM
|
|
|
|
CP0106454
|
(S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-5,6-dimethoxybenzamide
Show/Hide
|
C16H23BrN2O4
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0444357
|
5-bromo-2,3-dimethoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C17H23BrN2O3
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0389291
|
5-hydroxy-8-(4-propyl-1,4-diazepan-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
|
C16H23N3O3
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0171885
|
1-benzyl-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-5-propyltriazole-4-carboxamide
Show/Hide
|
C27H34Cl2N6O
|
1
|
| 1 |
Ki = 218.78 nM
|
|
|
|
CP0269448
|
N-[[4-(2-chlorophenyl)piperazin-1-yl]methyl]-4-methylbenzamide
Show/Hide
|
C19H22ClN3O
|
1
|
| 1 |
Ki = 218.78 nM
|
|
|
|
CP0041232
|
1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol
Show/Hide
|
C20H21ClN2O
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0400123
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-(2-phenylethynyl)benzamide
Show/Hide
|
C30H33N3O2
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0475764
|
N-[4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butyl]-2,5-dimethylbenzamide
Show/Hide
|
C25H35N3O
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0372550
|
3-(2-ethoxyethoxy)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C26H37N3O4
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0434336
|
(S)-1-(3-(3-(3,4-dimethoxyphenyl)-4,5-dihydroisoxazol-5-yl)propyl)-4-(2-ethoxyphenyl)piperazine
Show/Hide
|
C26H35N3O4
|
1
|
| 1 |
Ki = 225 nM
|
|
|
|
CP0400351
|
7-Methyl-6,7,8,9,10,15-hexahydroindolo[2,3-f][3]benzazecine
Show/Hide
|
C20H22N2
|
1
|
| 1 |
Ki = 225 nM
|
|
|
|
CP0401144
|
2-[1-(1-Benzyl-piperidin-4-yl)-1H-pyrrol-3-ylmethylene]-malononitrile
Show/Hide
|
C20H20N4
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0503157
|
N-[4-[1,2-diazatricyclo[6.3.1.04,12]dodeca-2,4(12),8,10-tetraen-6-yl(propyl)amino]butyl]-4-phenylbenzamide
Show/Hide
|
C30H34N4O
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0298050
|
Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine
Show/Hide
|
C17H18N2O
|
1
|
| 1 |
Ki = 230.2 nM
|
|
|
|
CP0897133
|
1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-(2-fluoro-phenyl)-piperazine hydrochloride
Show/Hide
|
C25H31ClFN3O3
|
1
|
| 1 |
Ki = 233 nM
|
|
|
|
CP0039223
|
N-[4-[4-(2-chlorophenyl)piperazin-1-yl]butyl]-4-phenylbenzamide
Show/Hide
|
C27H30ClN3O
|
1
|
| 1 |
Ki = 239.88 nM
|
|
|
|
CP0234092
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1-(4-methoxyphenyl)triazole-4-carboxamide
Show/Hide
|
C24H28Cl2N6O2
|
1
|
| 1 |
Ki = 240 nM
|
|
|
|
CP0372554
|
4-(2-ethoxyethoxymethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]benzamide
Show/Hide
|
C26H37N3O4
|
1
|
| 1 |
Ki = 240 nM
|
|
|
|
CP0399134
|
4-[(1S)-1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO5
|
1
|
| 1 |
Ki = 240 nM
|
|
|
|
CP0418859
|
1-Phenyl-4-(2-phenyl-oxazol-4-ylmethyl)-piperazine
Show/Hide
|
C20H21N3O
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0455077
|
5-iodo-2,3-dimethoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C17H23IN2O3
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0428514
|
4-(2-ethoxyethoxymethyl)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C27H39N3O4
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0881183
|
1-benzyl-N-(5-(4-(2,3-dichlorophenyl)piperazin-1-yl)pentyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide
Show/Hide
|
C26H32Cl2N6O
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0942040
|
1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-(2-methoxy-phenyl)-piperazine hydrochloride
Show/Hide
|
C26H34ClN3O4
|
1
|
| 1 |
Ki = 257 nM
|
|
|
|
CP0439814
|
1-Benzyl-4-phenyl-piperazine
Show/Hide
|
C17H20N2
|
1
|
| 1 |
Ki = 267 nM
|
|
|
|
CP0160140
|
1-[(4-methoxyphenyl)methyl]-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C28H38N6O3
|
1
|
| 1 |
Ki = 269.15 nM
|
|
|
|
CP0446910
|
8-hydroxy-5-[4-(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)piperazin-1-yl]chromen-2-one
Show/Hide
|
C24H26N4O4
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0202373
|
3-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene
Show/Hide
|
C20H25NO
|
1
|
| 1 |
Ki = 271 nM
|
|
|
|
CP0378555
|
4-(2-Benzylamino-ethoxy)-phenol
Show/Hide
|
C15H17NO2
|
1
|
| 1 |
Ki = 277 nM
|
|
|
|
CP0425965
|
2-[1-(1-Benzyl-piperidin-4-yl)-1H-pyrrol-2-ylmethylene]-malononitrile
Show/Hide
|
C20H20N4
|
1
|
| 1 |
Ki = 280 nM
|
|
|
|
CP0172633
|
1-[(4-methoxyphenyl)methyl]-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C27H36N6O3
|
1
|
| 1 |
Ki = 281.84 nM
|
|
|
|
CP0183951
|
1-benzyl-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C25H30Cl2N6O
|
1
|
| 1 |
Ki = 281.84 nM
|
|
|
|
CP0717117
|
4-chloro-N-(4-(4-(2-chlorophenyl)piperazin-1-yl)butyl)benzamide
Show/Hide
|
C21H25Cl2N3O
|
1
|
| 1 |
Ki = 281.84 nM
|
|
|
|
CP0172632
|
N-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-1-[(4-methoxyphenyl)methyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C27H34Cl2N6O2
|
1
|
| 1 |
Ki = 288.4 nM
|
|
|
|
CP0386244
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(2R)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C34H49N5O4
|
1
|
| 1 |
Ki = 290 nM
|
|
|
|
CP0432841
|
2-(2-Benzylamino-ethoxy)-phenol
Show/Hide
|
C15H17NO2
|
1
|
| 1 |
Ki = 297 nM
|
|
|
|
CP0505352
|
N-[4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C25H31N3OS
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0385663
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] octanedioate
Show/Hide
|
C50H56Cl2F2N2O6
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0384609
|
4-[(1R)-1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO5
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0393898
|
7-[4-[4-(5-hydroxy-2,3-dihydro-1,4-benzodioxin-8-yl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H31N3O5
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0416783
|
1-benzyl-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-propyltriazole-4-carboxamide
Show/Hide
|
C28H38N6O2
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0374994
|
(S)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine
Show/Hide
|
C21H26N4
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0371852
|
2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)pyrimidine
Show/Hide
|
C18H20N6
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0403563
|
(S)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one
Show/Hide
|
C18H19N3O2
|
1
|
| 1 |
Ki = 313 nM
|
|
|
|
CP0372695
|
Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine
Show/Hide
|
C16H17N3O
|
1
|
| 1 |
Ki = 315.5 nM
|
|
|
|
CP0375152
|
N-[4-[[(7R,9aS)-2-pyrimidin-2-yl-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-7-yl]methoxy]phenyl]acetamide
Show/Hide
|
C21H27N5O2
|
1
|
| 1 |
Ki = 316 nM
|
|
|
|
CP0373344
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-(2-phenylethynyl)benzamide
Show/Hide
|
C29H29Cl2N3O
|
1
|
| 1 |
Ki = 330 nM
|
|
|
|
CP0374745
|
3-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-2-methyl-2,3-dihydro-isoindol-1-one
Show/Hide
|
C22H27N3O2
|
1
|
| 1 |
Ki = 333 nM
|
|
|
|
CP0043442
|
Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H25Cl2N3OS
|
2
|
| 1 |
Ki = 338.84 nM
|
|
|
| 2 |
Ki = 340 nM
|
|
|
|
CP0461939
|
(2S,3S,4S,5R,6R)-2-(fluoromethyl)-6-[4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]triazol-1-yl]oxane-3,4,5-triol
Show/Hide
|
C20H28FN5O5
|
1
|
| 1 |
Ki = 340 nM
|
|
|
|
CP0938102
|
1-Phenyl-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C25H30ClN3O
|
1
|
| 1 |
Ki = 346 nM
|
|
|
|
CP0436855
|
(1-Benzyl-piperidin-4-yl)-(2-phenyl-oxazol-4-ylmethyl)-amine
Show/Hide
|
C22H25N3O
|
1
|
| 1 |
Ki = 350 nM
|
|
|
|
CP0125802
|
(R)-2-(Benzylamino-methyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indol-8-one
Show/Hide
|
C19H20N2O2
|
1
|
| 1 |
Ki = 359 nM
|
|
|
|
CP0276689
|
3-{[4-(4-Fluorophenyl)piperazin-1-yl]methyl}-2,5,7-trimethylimidazo[1,2-c]pyrimidine
Show/Hide
|
C20H24FN5
|
1
|
| 1 |
Ki = 360 nM
|
|
|
|
CP0395490
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-4-[2-[2-[2-[2-[2-[2-[2-[2-[[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylcarbamoyl]phenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]benzamide
Show/Hide
|
C60H88N6O13
|
1
|
| 1 |
Ki = 360 nM
|
|
|
|
CP0481705
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] heptanedioate
Show/Hide
|
C49H54Cl2F2N2O6
|
1
|
| 1 |
Ki = 360 nM
|
|
|
|
CP0402209
|
1-[2-(5-Bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-4-phenyl-piperazine
Show/Hide
|
C21H22BrN3O2
|
1
|
| 1 |
Ki = 370 nM
|
|
|
|
CP0430103
|
1-Benzyl-4-[2-(5-bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-piperazine
Show/Hide
|
C22H24BrN3OS
|
1
|
| 1 |
Ki = 370 nM
|
|
|
|
CP0376932
|
((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-(2-phenyl-thiazol-4-ylmethyl)-amine
Show/Hide
|
C22H25N3S
|
1
|
| 1 |
Ki = 390 nM
|
|
|
|
CP0401018
|
(1-Benzyl-piperidin-4-yl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-amine
Show/Hide
|
C23H26BrN3O2
|
1
|
| 1 |
Ki = 390 nM
|
|
|
|
CP0400954
|
(1-Benzyl-piperidin-4-yl)-[2-(5-bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-amine
Show/Hide
|
C23H26BrN3OS
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0392875
|
[(12R)-11-methyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaen-12-yl]methanol
Show/Hide
|
C21H24N2O
|
1
|
| 1 |
Ki = 408 nM
|
|
|
|
CP0897087
|
1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-o-tolyl-piperazine hydrochloride
Show/Hide
|
C26H34ClN3O3
|
1
|
| 1 |
Ki = 413 nM
|
|
|
|
CP0346837
|
8-methyl-5,6,7,8,9,10,11,16-octahydrodibenzo[e,h]azacyclododecene-3-ol
Show/Hide
|
C20H25NO
|
1
|
| 1 |
Ki = 422 nM
|
|
|
|
CP0458937
|
(R)-1-(bis(4-fluorophenyl)methyl)-4-(3-(3-(3,4-dimethoxyphenyl)-4,5-dihydroisoxazol-5-yl)propyl)piperazine
Show/Hide
|
C31H35F2N3O3
|
1
|
| 1 |
Ki = 426 nM
|
|
|
|
CP0423181
|
5-hydroxy-8-piperazin-1-yl-4H-1,4-benzoxazin-3-one
Show/Hide
|
C12H15N3O3
|
1
|
| 1 |
Ki = 440 nM
|
|
|
|
CP0401061
|
1-Phenyl-4-(2-phenyl-thiazol-4-ylmethyl)-piperazine
Show/Hide
|
C20H21N3S
|
1
|
| 1 |
Ki = 450 nM
|
|
|
|
CP0373496
|
(R)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6-dihydro-3H-pyrimidin-4-one
Show/Hide
|
C21H24N4O
|
1
|
| 1 |
Ki = 460 nM
|
|
|
|
CP0918977
|
1-[4-(3-Thiophen-2-yl-isoxazol-5-yl)-butyl]-4-o-tolyl-piperazine hydrochloride
Show/Hide
|
C22H28ClN3OS
|
1
|
| 1 |
Ki = 465 nM
|
|
|
|
CP0461950
|
(S)-1-(bis(4-fluorophenyl)methyl)-4-(3-(3-(3,4-dimethoxyphenyl)-4,5-dihydroisoxazol-5-yl)propyl)piperazine
Show/Hide
|
C31H35F2N3O3
|
1
|
| 1 |
Ki = 483 nM
|
|
|
|
CP0385668
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] decanedioate
Show/Hide
|
C52H60Cl2F2N2O6
|
1
|
| 1 |
Ki = 490 nM
|
|
|
|
CP0480635
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] tetradecanedioate
Show/Hide
|
C56H68Cl2F2N2O6
|
1
|
| 1 |
Ki = 490 nM
|
|
|
|
CP0481590
|
N-[3-[2-(benzylamino)ethoxy]phenyl]methanesulfonamide
Show/Hide
|
C16H20N2O3S
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0445951
|
2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyrazine
Show/Hide
|
C17H18FN5
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0434139
|
(2R,3S,4S,5R,6R)-5-fluoro-2-(hydroxymethyl)-6-[4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]triazol-1-yl]oxane-3,4-diol
Show/Hide
|
C20H28FN5O5
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0525899
|
(R)-1-(3-(3-(3,4-dimethoxyphenyl)-4,5-dihydroisoxazol-5-yl)propyl)-4-(2-ethoxyphenyl)piperazine
Show/Hide
|
C26H35N3O4
|
1
|
| 1 |
Ki = 507 nM
|
|
|
|
CP0466848
|
1-benzyl-N-[[2-(5-bromo-2-methoxyphenyl)-1,3-oxazol-4-yl]methyl]pyrrolidin-3-amine
Show/Hide
|
C22H24BrN3O2
|
1
|
| 1 |
Ki = 510 nM
|
|
|
|
CP0385665
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] nonanedioate
Show/Hide
|
C51H58Cl2F2N2O6
|
1
|
| 1 |
Ki = 520 nM
|
|
|
|
CP0906356
|
1-Phenyl-4-[4-(3-phenyl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C23H28ClN3O
|
1
|
| 1 |
Ki = 541 nM
|
|
|
|
CP0392475
|
5-Iodo-benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H24Cl2IN3OS
|
1
|
| 1 |
Ki = 550 nM
|
|
|
|
CP0460528
|
(2H-Benzo[1,4]oxazin-3-yl)-methyl-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-amine
Show/Hide
|
C21H28N6O
|
1
|
| 1 |
Ki = 558 nM
|
|
|
|
CP0436856
|
8-hydroxy-5-(4-methylpiperazin-1-yl)-1H-quinolin-2-one
Show/Hide
|
C14H17N3O2
|
1
|
| 1 |
Ki = 560 nM
|
|
|
|
CP0345574
|
3-(4-Methyl-piperidin-1-ylmethyl)-1H-indole
Show/Hide
|
C15H20N2
|
1
|
| 1 |
Ki = 570 nM
|
|
|
|
CP0433258
|
(-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide
Show/Hide
|
C15H21IN2O3
|
1
|
| 1 |
Ki = 570 nM
|
|
|
|
CP0463610
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] octadecanedioate
Show/Hide
|
C60H76Cl2F2N2O6
|
1
|
| 1 |
Ki = 570 nM
|
|
|
|
CP0504999
|
4-Bromo-2-[4-(4-phenyl-piperazin-1-ylmethyl)-oxazol-2-yl]-phenol
Show/Hide
|
C20H20BrN3O2
|
1
|
| 1 |
Ki = 580 nM
|
|
|
|
CP0382905
|
1-Benzyl-4-(2-phenyl-thiazol-4-ylmethyl)-piperazine
Show/Hide
|
C21H23N3S
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0463242
|
1-[2-(5-Bromo-2-methoxy-phenyl)-thiazol-4-ylmethyl]-4-phenyl-piperazine
Show/Hide
|
C21H22BrN3OS
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0805510
|
5-bromo-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
|
C23H25BrCl2N4O
|
1
|
| 1 |
Ki = 602.56 nM
|
|
|
|
CP0895107
|
1-Benzhydryl-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C32H36ClN3O
|
1
|
| 1 |
Ki = 603 nM
|
|
|
|
CP0455078
|
5-iodo-2-methoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C16H21IN2O2
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0717118
|
6-cyano-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
|
C24H25Cl2N5O
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0414816
|
((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-methyl-amine
Show/Hide
|
C24H28BrN3O2
|
1
|
| 1 |
Ki = 650 nM
|
|
|
|
CP0400541
|
3-methoxy-4-[3-[1-[8-[4-[3-[2-methoxy-4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butylcarbamoyl]phenoxy]propyl]triazol-1-yl]octyl]triazol-4-yl]propoxy]-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
Show/Hide
|
C64H90N12O8
|
1
|
| 1 |
Ki = 660 nM
|
|
|
|
CP0389515
|
N-[4-[cyclohexyl(propyl)amino]butyl]-4-phenylbenzamide
Show/Hide
|
C26H36N2O
|
1
|
| 1 |
Ki = 670 nM
|
|
|
|
CP0391221
|
1-[[1-[2-[2-[2-(2-fluoroethoxy)ethoxy]ethoxy]ethyl]triazol-4-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C22H34FN5O4
|
1
|
| 1 |
Ki = 680 nM
|
|
|
|
CP0890625
|
1-[4-(3-Phenyl-isoxazol-5-yl)-butyl]-4-o-tolyl-piperazine hydrochloride
Show/Hide
|
C24H30ClN3O
|
1
|
| 1 |
Ki = 683 nM
|
|
|
|
CP0422207
|
1-Benzyl-4-[2-(5-bromo-2-methoxy-phenyl)-oxazol-4-ylmethyl]-piperazine
Show/Hide
|
C22H24BrN3O2
|
1
|
| 1 |
Ki = 710 nM
|
|
|
|
CP0897086
|
1-{4-[3-(3,4-Dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-4-phenyl-piperazine hydrochloride
Show/Hide
|
C25H32ClN3O3
|
1
|
| 1 |
Ki = 774 nM
|
|
|
|
CP0861232
|
3-Cyclopentyl-N-(2-dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-propionamide with di TFA
Show/Hide
|
C38H47F6N3O5
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0386241
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C35H48N6O5
|
1
|
| 1 |
Ki = 800 nM
|
|
|
|
CP0463577
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] docosanedioate
Show/Hide
|
C64H84Cl2F2N2O6
|
1
|
| 1 |
Ki = 850 nM
|
|
|
|
CP0446907
|
7-[4-[4-(8-hydroxy-2-oxochromen-5-yl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H29N3O5
|
1
|
| 1 |
Ki = 870 nM
|
|
|
|
CP0415946
|
N-[4-[4-(5-tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaenyl)piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C33H37N3OS
|
1
|
| 1 |
Ki = 880 nM
|
|
|
|
CP0408430
|
5-hydroxy-8-(4-propylpiperazin-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
|
C15H21N3O3
|
1
|
| 1 |
Ki = 880 nM
|
|
|
|
CP0401111
|
8-hydroxy-5-[2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C29H32N2O4
|
1
|
| 1 |
Ki = 900 nM
|
|
|
|
CP0163622
|
3-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-propionitrile
Show/Hide
|
C25H25FN6
|
1
|
| 1 |
Ki = 920 nM
|
|
|
|
CP0448425
|
1-Benzyl-4-(2-ethynyl-pyrrol-1-yl)-piperidine
Show/Hide
|
C18H20N2
|
1
|
| 1 |
Ki = 940 nM
|
|
|
|
CP0401045
|
1-(1-Benzyl-piperidin-4-yl)-1H-pyrrole-3-carbaldehyde
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
Ki = 960 nM
|
|
|
|
CP0293355
|
3-{[4-(4-Methoxyphenyl)piperazin-1-yl]methyl}2,5,7-rimethylimidazo[1,2-c]pyrimidine
Show/Hide
|
C21H27N5O
|
1
|
| 1 |
Ki = 960 nM
|
|
|
|
CP0330402
|
1-benzyl-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-methyltriazole-4-carboxamide
Show/Hide
|
C26H34N6O2
|
1
|
| 1 |
Ki = 977.24 nM
|
|
|
|
CP0399131
|
4-[(1S)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0464939
|
1-Benzyl-4-pyrrol-1-yl-piperidine
Show/Hide
|
C16H20N2
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0474566
|
4-(2-phenylethynyl)-N-[4-[4-(4-phenylphenyl)triazol-1-yl]butyl]-N-propylcyclohex-3-en-1-amine
Show/Hide
|
C35H38N4
|
1
|
| 1 |
Ki = 1100 nM
|
|
|
|
CP0040677
|
12-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene
Show/Hide
|
C20H25NO
|
1
|
| 1 |
Ki = 1103 nM
|
|
|
|
CP0467902
|
((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(5-bromo-2-methoxy-phenyl)-1H-imidazol-4-ylmethyl]-amine
Show/Hide
|
C23H27BrN4O
|
1
|
| 1 |
Ki = 1110 nM
|
|
|
|
CP0878620
|
1-Benzhydryl-4-{4-[3-(2,4-dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
|
C32H38ClN3O3
|
1
|
| 1 |
Ki = 1118 nM
|
|
|
|
CP0853819
|
(E)-N-(2-Dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-acrylamide TFA
Show/Hide
|
C37H40F3N3O3
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0400288
|
5-(3-fluoropropyl)-2,3-dimethoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C20H29FN2O3
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0900199
|
1-Benzhydryl-4-{4-[3-(4-fluoro-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
|
C30H33ClFN3O
|
1
|
| 1 |
Ki = 1346 nM
|
|
|
|
CP0409703
|
4-[4-(2-Phenyl-3H-imidazol-4-ylmethyl)-piperazin-1-yl]-pyrimidine
Show/Hide
|
C18H20N6
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0398439
|
N-[4-(dipropylamino)butyl]-4-phenylbenzamide
Show/Hide
|
C23H32N2O
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0385670
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] hexadecanedioate
Show/Hide
|
C58H72Cl2F2N2O6
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0413702
|
5-[4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C24H25Cl2N7O
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0401112
|
5-hydroxy-8-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C28H32N2O6
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0398979
|
2-(4-{[(2S)-8-Methyl-2,3-dihydro[1,4]dioxino[2,3-f]quinolin-2-yl]methyl}piperazin-1-yl)-quinoline-6-carbonitrile
Show/Hide
|
C27H25N5O2
|
1
|
| 1 |
Ki = 1418 nM
|
|
|
|
CP0466278
|
1-Benzyl-4-(2-phenyl-oxazol-4-ylmethyl)-piperazine
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
Ki = 1450 nM
|
|
|
|
CP0391923
|
1-Benzyl-4-(2-iodo-pyrrol-1-yl)-piperidine
Show/Hide
|
C16H19IN2
|
1
|
| 1 |
Ki = 1500 nM
|
|
|
|
CP0847634
|
(E)-N-[4'-(Phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-N-pyridin-3-ylmethyl-acrylamide TFA
Show/Hide
|
C39H36F3N3O3
|
1
|
| 1 |
Ki = 1584.89 nM
|
|
|
|
CP0375964
|
(R)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine
Show/Hide
|
C22H27BrN4O
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
|
CP0897820
|
1-{4-[3-(3-Nitro-phenyl)-isoxazol-5-yl]-butyl}-4-phenyl-piperazine hydrochloride
Show/Hide
|
C23H27ClN4O3
|
1
|
| 1 |
Ki = 1697 nM
|
|
|
|
CP0042204
|
1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H26Cl2N4O
|
1
|
| 1 |
Ki = 1698.24 nM
|
|
|
|
CP0433256
|
5-bromo-2-methoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C16H21BrN2O2
|
1
|
| 1 |
Ki = 1700 nM
|
|
|
|
CP0389511
|
N-[4-[4-(4-phenylphenyl)triazol-1-yl]butyl]-N-propyl-4-(2-trimethylsilylethynyl)cyclohex-3-en-1-amine
Show/Hide
|
C32H42N4Si
|
1
|
| 1 |
Ki = 1800 nM
|
|
|
|
CP0086686
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-[1-(4-methoxyphenyl)triazol-4-yl]butanamide
Show/Hide
|
C27H34Cl2N6O2
|
1
|
| 1 |
Ki = 1800 nM
|
|
|
|
CP0449378
|
2-[4-(3,4-dichlorophenyl)piperazin-1-ylmethyl]-6-(4-methylpiperazin-1-yl)imidazo[1,2-b]pyridazine
Show/Hide
|
C22H27Cl2N7
|
1
|
| 1 |
Ki = 1900 nM
|
|
|
|
CP0045385
|
CAS_15676-16-1
Show/Hide
|
C15H23N3O4S
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0393916
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[4-(8-hydroxy-2-oxo-1H-quinolin-5-yl)-1,4-diazepan-1-yl]butyl]-3-methoxybenzamide
Show/Hide
|
C35H47N7O5
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0894976
|
1-Benzhydryl-4-[4-(3-thiophen-2-yl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C28H32ClN3OS
|
1
|
| 1 |
Ki = 2145 nM
|
|
|
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CP0272971
|
Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]indol-2-yl)methyl]-amine
Show/Hide
|
C19H20N2O
|
1
|
| 1 |
Ki = 2174 nM
|
|
|
|
CP0376022
|
5-Chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-N-(S)-pyrrolidin-3-yl-benzamide
Show/Hide
|
C16H20ClN3O3
|
1
|
| 1 |
Ki = 2200 nM
|
|
|
|
CP0253779
|
5-Iodo-benzofuran-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H24Cl2IN3O2
|
1
|
| 1 |
Ki = 2200 nM
|
|
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CP0385669
|
bis[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] dodecanedioate
Show/Hide
|
C54H64Cl2F2N2O6
|
1
|
| 1 |
Ki = 2200 nM
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|
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CP0869073
|
1-Benzhydryl-4-[4-(3-phenyl-isoxazol-5-yl)-butyl]-piperazine hydrochloride
Show/Hide
|
C30H34ClN3O
|
1
|
| 1 |
Ki = 2243 nM
|
|
|
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CP0378665
|
7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene-12-ol
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki = 2258 nM
|
|
|
|
CP0894585
|
1-Benzhydryl-4-{4-[3-(3-nitro-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
|
C30H33ClN4O3
|
1
|
| 1 |
Ki = 2314 nM
|
|
|
|
CP0428513
|
N-[4-[4-[4-(2-ethoxyethoxymethyl)-2-methoxyphenyl]piperazin-1-yl]butyl]benzamide
Show/Hide
|
C27H39N3O4
|
1
|
| 1 |
Ki = 2400 nM
|
|
|
|
CP0878622
|
1-Benzhydryl-4-{4-[3-(3,4-dimethoxy-phenyl)-isoxazol-5-yl]-butyl}-piperazine hydrochloride
Show/Hide
|
C32H38ClN3O3
|
1
|
| 1 |
Ki = 2438 nM
|
|
|
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CP0375584
|
3-Methoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline
Show/Hide
|
C18H19NO
|
1
|
| 1 |
Ki = 2565 nM
|
|
|
|
CP0408429
|
8-(4-methylpiperazin-1-yl)-2,3-dihydro-1,4-benzodioxin-5-ol
Show/Hide
|
C13H18N2O3
|
1
|
| 1 |
Ki = 2600 nM
|
|
|
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CP0469565
|
1-Benzyl-4-(2-trimethylsilanylethynyl-pyrrol-1-yl)-piperidine
Show/Hide
|
C21H28N2Si
|
1
|
| 1 |
Ki = 2700 nM
|
|
|
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CP0277602
|
2-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene
Show/Hide
|
C20H25NO
|
1
|
| 1 |
Ki = 2763 nM
|
|
|
|
CP0456414
|
2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyrimidine
Show/Hide
|
C17H18FN5
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0363247
|
3-methoxy-8-methyl-5,6,7,8,9,10,11,16-octahydrodibenzo[e,h]azacyclododecene
Show/Hide
|
C21H27NO
|
1
|
| 1 |
Ki = 2869 nM
|
|
|
|
CP0068209
|
4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride
Show/Hide
|
C11H17NO3
|
1
|
| 1 |
Ki = 2900 nM
|
|
|
|
CP0433257
|
5-(3-fluoropropyl)-2-methoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C19H27FN2O2
|
1
|
| 1 |
Ki = 3000 nM
|
|
|
|
CP0151333
|
1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
|
C27H30FN7O
|
1
|
| 1 |
Ki = 3000 nM
|
|
|
|
CP0413705
|
5-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C22H21Cl2N7O
|
1
|
| 1 |
Ki = 3000 nM
|
|
|
|
CP0838145
|
5-bromo-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
Show/Hide
|
C23H24BrCl2N3O2
|
1
|
| 1 |
Ki = 3090.3 nM
|
|
|
|
CP0036333
|
(S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide
Show/Hide
|
C15H20Cl2N2O3
|
1
|
| 1 |
Ki = 3100 nM
|
|
|
|
CP0474504
|
4-phenyl-N-[4-[[4-(2-phenylethynyl)cyclohex-3-en-1-yl]-propylamino]butyl]benzamide
Show/Hide
|
C34H38N2O
|
1
|
| 1 |
Ki = 3100 nM
|
|
|
|
CP0458291
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[3-[4-(8-hydroxy-2-oxo-1H-quinolin-5-yl)-1,4-diazepan-1-yl]propyl]-3-methoxybenzamide
Show/Hide
|
C34H45N7O5
|
1
|
| 1 |
Ki = 3200 nM
|
|
|
|
CP0377732
|
1-Benzyl-4-(2-phenylethynyl-pyrrol-1-yl)-piperidine
Show/Hide
|
C24H24N2
|
1
|
| 1 |
Ki = 3300 nM
|
|
|
|
CP0399132
|
8-hydroxy-5-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C29H32N2O5
|
1
|
| 1 |
Ki = 3300 nM
|
|
|
|
CP0442599
|
(S)-2-(5-Bromo-2-methoxy-phenyl)-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine
Show/Hide
|
C22H27BrN4O
|
1
|
| 1 |
Ki = 3500 nM
|
|
|
|
CP0333143
|
3-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-1H-quinazoline-2,4-dione
Show/Hide
|
C32H30FN7O2
|
1
|
| 1 |
Ki = 3600 nM
|
|
|
|
CP0432261
|
(S)-2-Phenyl-6-(4-phenyl-piperazin-1-ylmethyl)-5,6-dihydro-3H-pyrimidin-4-one
Show/Hide
|
C21H24N4O
|
1
|
| 1 |
Ki = 3700 nM
|
|
|
|
CP0089986
|
STEPHOLIDINE
Show/Hide
|
C19H21NO4
|
1
|
| 1 |
Ki = 3748 nM
|
|
|
|
CP0286302
|
7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene-2-ol
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki = 3751 nM
|
|
|
|
CP0286303
|
6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecin-12-ol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki = 4256 nM
|
|
|
|
CP0228798
|
1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
|
C26H29FN8O
|
1
|
| 1 |
Ki = 4300 nM
|
|
|
|
CP0381041
|
(R)-2-Phenyl-5-(4-phenyl-piperazin-1-yl)-4,5,6,7-tetrahydro-1H-[1,3]diazepine
Show/Hide
|
C21H26N4
|
1
|
| 1 |
Ki = 4400 nM
|
|
|
|
CP0408615
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C25H32F3N7O
|
1
|
| 1 |
Ki = 4700 nM
|
|
|
|
CP0431323
|
[(12S)-11-methyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaen-12-yl]methanol
Show/Hide
|
C21H24N2O
|
1
|
| 1 |
Ki = 4861 nM
|
|
|
|
CP0343878
|
3-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-oxazolidin-2-one
Show/Hide
|
C27H29FN6O2
|
1
|
| 1 |
Ki = 4900 nM
|
|
|
|
CP0436909
|
5-hydroxy-8-(4-methyl-1,4-diazepan-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
|
C14H19N3O3
|
1
|
| 1 |
Ki = 4900 nM
|
|
|
|
CP0393652
|
7-[4-[4-(8-hydroxy-2-oxochromen-5-yl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C27H31N3O5
|
1
|
| 1 |
Ki = 5000 nM
|
|
|
|
CP0341419
|
5,6-dimethoxy-11-methyl-11-aza-tricyclo[13.4.0.0.3,8]nonadeca-1(15),3(8),4,6,16,18-hexaene
Show/Hide
|
C21H27NO2
|
1
|
| 1 |
Ki = 5048 nM
|
|
|
|
CP0430707
|
5,8,13,13a-Tetrahydro-6H-isoquino[3,2-a]isoquinolin-3-ol
Show/Hide
|
C17H17NO
|
1
|
| 1 |
Ki = 5092 nM
|
|
|
|
CP0393675
|
N-[4-[4-[4-[2-[2-[2-[2-[[4-[4-(4-benzamidobutyl)piperazin-1-yl]-3-methoxyphenyl]methoxy]ethoxy]ethoxy]ethoxy]ethoxymethyl]-2-methoxyphenyl]piperazin-1-yl]butyl]benzamide
Show/Hide
|
C54H76N6O9
|
1
|
| 1 |
Ki = 5400 nM
|
|
|
|
CP0419868
|
5-hydroxy-8-[(1S)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C28H32N2O6
|
1
|
| 1 |
Ki = 5400 nM
|
|
|
|
CP0267173
|
3-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-oxazolidin-2-one
Show/Hide
|
C26H28FN7O2
|
1
|
| 1 |
Ki = 5700 nM
|
|
|
|
CP0389514
|
4-phenyl-N-[4-(propylamino)butyl]benzamide
Show/Hide
|
C20H26N2O
|
1
|
| 1 |
Ki = 6100 nM
|
|
|
|
CP0408583
|
8-hydroxy-5-piperazin-1-yl-1H-quinolin-2-one
Show/Hide
|
C13H15N3O2
|
1
|
| 1 |
Ki = 6100 nM
|
|
|
|
CP0503155
|
N-[4-[(3-formyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-yl)-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H34N4O2
|
1
|
| 1 |
Ki = 6300 nM
|
|
|
|
CP0277576
|
1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
|
C28H31FN6O
|
1
|
| 1 |
Ki = 6400 nM
|
|
|
|
CP0375574
|
6-Methoxy-2-methyl-1-(2-methylbenzyl)-1,2,3,4-tetrahydroisoquinoline
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki = 6644 nM
|
|
|
|
CP0105167
|
3-{4-[1-(4-Fluoro-phenyl)-5-pyrimidin-2-yl-1H-indol-3-yl]-piperidin-1-yl}-propionitrile
Show/Hide
|
C26H24FN5
|
1
|
| 1 |
Ki = 7000 nM
|
|
|
|
CP0320413
|
3-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-1-methyl-pyrrolidin-2-one
Show/Hide
|
C29H33FN6O
|
1
|
| 1 |
Ki = 7200 nM
|
|
|
|
CP0134581
|
3-(2-{4-[1-(4-Fluoro-phenyl)-5-pyrimidin-2-yl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-oxazolidin-2-one
Show/Hide
|
C28H28FN5O2
|
1
|
| 1 |
Ki = 7500 nM
|
|
|
|
CP0389230
|
8-hydroxy-5-(4-propylpiperazin-1-yl)-1H-quinolin-2-one
Show/Hide
|
C16H21N3O2
|
1
|
| 1 |
Ki = 7600 nM
|
|
|
|
CP0040814
|
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone
Show/Hide
|
C19H21N5O4
|
1
|
| 1 |
Ki = 8300 nM
|
|
|
|
CP0399136
|
8-hydroxy-5-[(1S)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C29H32N2O5
|
1
|
| 1 |
Ki = 9200 nM
|
|
|
|
CP0040673
|
2-[2-(3-chloro-4-methoxyphenyl)ethyl]-2,3,4,5-tetrahydro-1H-2-benzazepine
Show/Hide
|
C19H22ClNO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0040675
|
3-methoxy-6,7,9,10,11,15b-hexahydro-5H-[2]benzazepino[1,2-a][2]benzazepine
Show/Hide
|
C20H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0277604
|
3-chloro-2-methoxy-5,6,8,9,10,14b-hexahydroisoquino[1,2-a][2]benzazepine
Show/Hide
|
C19H20ClNO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0287080
|
3-methoxy-5,8,9,13b-tetrahydro-6H-isoquino-[1,2-a]isoquinoline
Show/Hide
|
C18H19NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375575
|
6-Methyl-5,6,7,8,9,14-hexahydrodibenzo[c,f]azecin-11-ol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375577
|
10-methyl-17,19-dioxa-10-azatetracyclo[12.7.0.0^{2,7}.0^{16,20}]henicosa-1(14),2(7),3,5,15,20-hexaene
Show/Hide
|
C19H21NO2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375581
|
10-Methoxy-6-methyl-5,6,7,8,13,14-hexahydrodibenzo[c,g]azecine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375582
|
2-Methyl-1-(2-methylbenzyl)-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375583
|
6-Methyl-5,6,7,8,13,14-hexahydrodibenzo[c,g]azecin-10-ol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375585
|
3-Methoxy-6,7,9,13b-tetrahydro-5H-isoindolo[1,2-a][2]benzazepine
Show/Hide
|
C18H19NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0428950
|
11-Methoxy-6-methyl-5,6,7,8,9,14-hexahydrodibenzo[c,f]azecine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0430705
|
6,8,9,13b-tetrahydro-5H-isoquinolino[1,2-a]isoquinolin-3-ol
Show/Hide
|
C17H17NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0470276
|
3-(2-Ethyl-4-methoxyphenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinoline
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0373716
|
5-Methyl-4,5,6,7-tetrahydroindolo[4,3a,3-ef][3]benzazecine
Show/Hide
|
C19H20N2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0400347
|
2,6,7,9,10,14b-Hexahydroindolo[3',4':3,4,5]azepino[2,1-a]-isoquinoline
Show/Hide
|
C19H18N2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0401522
|
5,6,8,9,10,14c-Hexahydroindolo[3',2':3,4,]pyrido[2,1-a]isoquinoline
Show/Hide
|
C19H18N2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0429881
|
2,8,9,13b-Tetrahydro-6H-isoquino[2,1-b]pyrrolo[4,3,2-de]-isoquinoline
Show/Hide
|
C18H16N2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0392876
|
(12R)-11,12-dimethyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaene
Show/Hide
|
C21H24N2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0392877
|
11-methyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaene-12-carboxylic acid
Show/Hide
|
C21H22N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0408616
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C26H32F3N5OS
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0862635
|
4'-(4-(pyrazolo[1,5-a]pyridine-2-carboxamido)butyl)-2,3-dihydrospiro[benzo[b][1,4]oxazine-4,1'-piperazin]-4-ium 4-methylbenzenesulfonate
Show/Hide
|
C31H37N5O5S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0051911
|
(5R)-N,N-dipropyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-5-amine
Show/Hide
|
C13H23N3
|
2
|
| 1 |
Ki = 13000 nM
|
|
|
| 2 |
Ki = 17000 nM
|
|
|
|
CP0295827
|
5-Dipropylamino-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C14H23N3O
|
1
|
| 1 |
Ki = 14000 nM
|
|
|
|
CP0408428
|
8-(1,4-diazepan-1-yl)-5-hydroxy-4H-1,4-benzoxazin-3-one
Show/Hide
|
C13H17N3O3
|
1
|
| 1 |
Ki > 15000 nM
|
|
|
|
CP0454857
|
((S)-1-Benzyl-pyrrolidin-3-ylmethyl)-[2-(4-bromo-1-methoxy-naphthalen-2-yl)-oxazol-4-ylmethyl]-amine
Show/Hide
|
C27H28BrN3O2
|
1
|
| 1 |
Ki = 15500 nM
|
|
|
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CP0237813
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(5-Dipropylamino-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridin-3-yl)-methanol
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C14H25N3O
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1
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| 1 |
Ki = 16000 nM
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CP0380080
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1-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-4-(4-fluorophenyl)butane-1,4-dione
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C21H21ClFNO3
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1
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| 1 |
Ki = 18000 nM
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CP0477390
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8-piperazin-1-yl-2,3-dihydro-1,4-benzodioxin-5-ol
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C12H16N2O3
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1
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| 1 |
Ki > 18000 nM
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CP0251113
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5-Dipropylamino-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine-3-carboxylic acid methyl ester
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C15H25N3O2
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1
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| 1 |
Ki > 20000 nM
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CP0477396
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8-(4-propylpiperazin-1-yl)-2,3-dihydro-1,4-benzodioxin-5-ol
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C15H22N2O3
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1
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| 1 |
Ki > 20000 nM
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CP0297053
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5-Propylamino-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine-3-carboxylic acid methyl ester
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C12H19N3O2
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1
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| 1 |
Ki = 90000 nM
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CP0073485
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1-benzyl-4-(3-hydroxyphenyl)piperazine
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C17H20N2O
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1
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| 1 |
Ki > 400 nM
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CP0380149
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N-[2-fluoro-5-[2-(thiophen-2-ylmethylamino)ethoxy]phenyl]methanesulfonamide
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C14H17FN2O3S2
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1
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| 1 |
Ki > 400 nM
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CP0399395
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2-(4-Benzyl-piperazin-1-yl)-phenol
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C17H20N2O
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1
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| 1 |
Ki > 400 nM
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CP0470957
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4-[2-(3-Phenoxy-propylamino)-ethoxy]-benzoic acid
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C18H21NO4
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1
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| 1 |
Ki > 1000 nM
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CP0037227
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7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
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C16H25NO
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1
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| 1 |
Ki > 1515 nM
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CP0405355
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3-Piperidin-1-ylmethyl-1H-indole
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C14H18N2
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1
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| 1 |
Ki > 2600 nM
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CP0306958
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(3aR,9bS) 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol
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C15H21NO
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1
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| 1 |
Ki > 4067 nM
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CP0436932
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(7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1-oxa-8-aza-dicyclopenta[a,h]naphthalene
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C17H21NO
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1
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| 1 |
Ki > 4067 nM
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CP0480448
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1-(2-Phenyl-3H-imidazol-4-ylmethyl)-4-pyridin-4-yl-piperazine
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C19H21N5
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1
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| 1 |
Ki > 7300 nM
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