Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(-)-Pramipexole
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 PubChem ID
CID: 119570
SID: 14748917
Canonical SMILES
CCCN[C@H]1CCc2nc(N)sc2C1
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Compound Formula C10H17N3S
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 8.1 nM
   TI
   LI
   LO
   TS
2
Ki = 130 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 138 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 29 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 8.5 nM