Brief Information of the Compound and Protein
Compound Name
6-iodo-2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine
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PubChem ID
CID: 11583188
SID: 16685624
Canonical SMILES
COc1ccccc1N1CCN(Cc2cn3cc(I)ccc3n2)CC1
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Compound Formula C19H21IN4O
Compound Structure
Protein Name
D(4) dopamine receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 0.52 nM
   TI
   LI
   LO
   TS
2
Ki = 0.33 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.33 nM