Brief Information of the Compound and Protein
Compound Name
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
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PubChem ID
CID: 135398745
SID: 14923451
Canonical SMILES
CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12
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Compound Formula C17H20N4S
Compound Structure
Protein Name
D(4) dopamine receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
IC50 = 173 nM
   TI
   LI
   LO
   TS
2
Ki = 19.95 nM
   TI
   LI
   LO
   TS
3
Ki = 29 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 19 nM
2 Ki = 28 nM
3 Ki = 50 nM
4 Ki = 100 nM