| Compound ID |
Compound Name |
Compound Formula |
|
CP0357622
|
3-[3-(4-Benzyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H28N6
|
5
|
| 1 |
EC50 = 0.1 nM
|
|
|
| 2 |
EC50 = 0.2 nM
|
|
|
| 3 |
IC50 = 0.1 nM
|
|
|
| 4 |
IC50 = 0.14 nM
|
|
|
| 5 |
IC50 = 0.2 nM
|
|
|
|
CP0421403
|
3-{3-[4-Fluoro-4-(2-trifluoromethyl-benzyl)-piperidin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H27F4N5
|
2
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 0.3 nM
|
|
|
|
CP0393693
|
2-Phenyl-2-{4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-1-yl}-acetamide
Show/Hide
|
C25H29N7O
|
4
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
EC50 = 3.8 nM
|
|
|
| 3 |
IC50 = 0.2 nM
|
|
|
| 4 |
IC50 = 2.3 nM
|
|
|
|
CP0403825
|
N-[3-[[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]methyl]phenyl]acetamide
Show/Hide
|
C26H31N7O
|
2
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 0.2 nM
|
|
|
|
CP0123953
|
(1-Methyl-1-phenyl-ethyl)-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C26H32N6
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 1 nM
|
|
|
|
CP0377777
|
3-{3-[4-(2-Phenyl-propyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H32N6
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 0.8 nM
|
|
|
|
CP0377816
|
3-[3-(4-Pyridin-3-ylmethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H27N7
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 0.3 nM
|
|
|
|
CP0407101
|
3-[3-(4-Furan-3-ylmethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C22H26N6O
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 1.1 nM
|
|
|
|
CP0438815
|
3-[3-(4-Pyridin-2-ylmethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H27N7
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 0.4 nM
|
|
|
|
CP0448268
|
3-{3-[4-(4-Fluoro-benzyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H27FN6
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 0.1 nM
|
|
|
|
CP0460899
|
2-Phenyl-2-{4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-1-yl}-ethanol
Show/Hide
|
C25H30N6O
|
2
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 0.7 nM
|
|
|
|
CP0308736
|
3-[3-(4-Benzyl-4-fluoro-piperidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28FN5
|
4
|
| 1 |
EC50 = 0.4 nM
|
|
|
| 2 |
EC50 = 0.5 nM
|
|
|
| 3 |
IC50 = 0.9 nM
|
|
|
| 4 |
IC50 = 1 nM
|
|
|
|
CP0438469
|
N,N-dimethyl-2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethanamine
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|
C14H17N5
|
3
|
| 1 |
EC50 = 0.4 nM
|
|
|
| 2 |
EC50 = 0.45 nM
|
|
|
| 3 |
IC50 = 0.3 nM
|
|
|
|
CP0380853
|
3-((2R,3aR,6aR)-5-Benzyl-1-methyl-octahydro-pyrrolo[3,4-b]pyrrol-2-ylmethyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28N6
|
2
|
| 1 |
EC50 = 0.5 nM
|
|
|
| 2 |
IC50 = 0.9 nM
|
|
|
|
CP0502338
|
N-[1-(4-fluorophenyl)ethyl]-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C26H31FN6
|
2
|
| 1 |
EC50 = 0.5 nM
|
|
|
| 2 |
IC50 = 1.9 nM
|
|
|
|
CP0115159
|
(S)-4-[3-(2-{(S)-3-[((S)-1-Phenyl-ethylamino)-methyl]-pyrrolidin-1-yl}-ethyl)-1H-indol-5-ylmethyl]-oxazolidin-2-one
Show/Hide
|
C27H34N4O2
|
2
|
| 1 |
EC50 = 0.5 nM
|
|
|
| 2 |
IC50 = 0.3 nM
|
|
|
|
CP0448900
|
3-[3-(4-Furan-2-ylmethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C22H26N6O
|
2
|
| 1 |
EC50 = 0.5 nM
|
|
|
| 2 |
IC50 = 0.4 nM
|
|
|
|
CP0438357
|
3-(3-{4-[2-(3,5-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28F2N6
|
2
|
| 1 |
EC50 = 0.6 nM
|
|
|
| 2 |
IC50 = 0.7 nM
|
|
|
|
CP0101123
|
3-[3-(4-Benzyl-piperidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H29N5
|
3
|
| 1 |
EC50 = 0.6 nM
|
|
|
| 2 |
IC50 = 0.3 nM
|
|
|
| 3 |
IC50 = 0.35 nM
|
|
|
|
CP0448973
|
3-[3-(4-Pyrimidin-2-yl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C21H24N8
|
2
|
| 1 |
EC50 = 0.6 nM
|
|
|
| 2 |
IC50 = 0.6 nM
|
|
|
|
CP0378028
|
((S)-1-Phenyl-ethyl)-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C25H30N6
|
2
|
| 1 |
EC50 = 0.63 nM
|
|
|
| 2 |
IC50 = 0.45 nM
|
|
|
|
CP0384114
|
3-(3-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28F2N6
|
4
|
| 1 |
EC50 = 0.7 nM
|
|
|
| 2 |
EC50 = 1.9 nM
|
|
|
| 3 |
IC50 = 0.9 nM
|
|
|
| 4 |
IC50 = 1 nM
|
|
|
|
CP0079840
|
Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C24H28N6
|
4
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
EC50 = 0.93 nM
|
|
|
| 3 |
IC50 = 0.5 nM
|
|
|
| 4 |
IC50 = 0.6 nM
|
|
|
|
CP0395135
|
(R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
|
C26H31FN6O
|
4
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
EC50 = 1.1 nM
|
|
|
| 3 |
IC50 = 0.9 nM
|
|
|
| 4 |
Ki = 0.9 nM
|
|
|
|
CP0466543
|
(R)-2-{1-[3-(5-Imidazol-1-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-2-phenyl-ethanol
Show/Hide
|
C27H33N5O
|
2
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
IC50 = 0.7 nM
|
|
|
|
CP0438471
|
N,N-dimethyl-2-phenyl-2-[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]acetamide
Show/Hide
|
C27H33N7O
|
2
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
IC50 = 1 nM
|
|
|
|
CP0372707
|
3-[3-(4-Phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H30N6
|
3
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
EC50 = 1.7 nM
|
|
|
| 3 |
IC50 = 1.4 nM
|
|
|
|
CP0437579
|
Benzyl-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine
Show/Hide
|
C27H34N6
|
3
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
IC50 = 0.9 nM
|
|
|
| 3 |
IC50 = 0.95 nM
|
|
|
|
CP0382929
|
((R)-2-Methoxy-1-phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C27H34N6O
|
2
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
|
CP0190295
|
3-[3-(4-Benzyl-piperidin-1-yl)-2-fluoro-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28FN5
|
4
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
EC50 = 11 nM
|
|
|
| 3 |
IC50 = 0.9 nM
|
|
|
| 4 |
IC50 = 0.95 nM
|
|
|
|
CP0377135
|
(1R,2R)-1-Phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-2-ol
Show/Hide
|
C27H34N6O
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
IC50 = 0.9 nM
|
|
|
|
CP0136962
|
3-(3-{4-[2-(3-Fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H29FN6
|
4
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
EC50 = 1.2 nM
|
|
|
| 3 |
IC50 = 0.5 nM
|
|
|
| 4 |
IC50 = 0.6 nM
|
|
|
|
CP0410485
|
3-[3-(4-Pyridin-4-ylmethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H27N7
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
IC50 = 0.6 nM
|
|
|
|
CP0386020
|
1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0438816
|
4-{4-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-1-ylmethyl}-benzonitrile
Show/Hide
|
C25H27N7
|
2
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
IC50 = 0.7 nM
|
|
|
|
CP0380877
|
3-((2R,3aR,6aR)-5-Benzyl-1-methyl-octahydro-pyrrolo[3,4-b]pyrrol-2-ylmethyl)-5-imidazol-1-yl-1H-indole
Show/Hide
|
C26H29N5
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
IC50 = 0.7 nM
|
|
|
|
CP0410463
|
3-{3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H27ClN6
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
IC50 = 0.5 nM
|
|
|
|
CP0439877
|
N-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]-2,3-dihydro-1H-inden-1-amine
Show/Hide
|
C28H34N6
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 1.1 nM
|
|
|
|
CP0406034
|
N-(furan-3-ylmethyl)-1-[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanamine
Show/Hide
|
C22H26N6O
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 0.45 nM
|
|
|
|
CP0377784
|
3-(3-{4-[2-(2-Fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H29FN6
|
4
|
| 1 |
EC50 = 1.4 nM
|
|
|
| 2 |
EC50 = 1.5 nM
|
|
|
| 3 |
IC50 = 0.5 nM
|
|
|
| 4 |
IC50 = 0.6 nM
|
|
|
|
CP0374169
|
3-(3-{4-[2-(4-Fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H29FN6
|
2
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
IC50 = 0.8 nM
|
|
|
|
CP0474635
|
((R)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C26H32N6
|
4
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
EC50 = 13 nM
|
|
|
| 3 |
IC50 = 0.35 nM
|
|
|
| 4 |
IC50 = 0.4 nM
|
|
|
|
CP0376606
|
Benzyl-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C26H32N6
|
4
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
EC50 = 1.6 nM
|
|
|
| 3 |
IC50 = 2.1 nM
|
|
|
| 4 |
IC50 = 2.2 nM
|
|
|
|
CP0398518
|
Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C25H30N6
|
3
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
EC50 = 1.6 nM
|
|
|
| 3 |
IC50 = 0.7 nM
|
|
|
|
CP0454584
|
N-[3-[2-[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]ethyl]phenyl]acetamide
Show/Hide
|
C27H33N7O
|
2
|
| 1 |
EC50 = 1.6 nM
|
|
|
| 2 |
IC50 = 1.8 nM
|
|
|
|
CP0395029
|
3-(2-Fluoro-3-{4-[2-(4-fluoro-phenyl)-propyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H30F2N6
|
2
|
| 1 |
EC50 = 1.6 nM
|
|
|
| 2 |
IC50 = 1 nM
|
|
|
|
CP0384190
|
(R)-2-(4-Fluoro-phenyl)-2-{1-[2-fluoro-3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
|
C26H30F2N6O
|
2
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
IC50 = 1.4 nM
|
|
|
|
CP0375894
|
(R)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
|
C26H32N6O
|
3
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
EC50 = 1.8 nM
|
|
|
| 3 |
IC50 = 1.3 nM
|
|
|
|
CP0056703
|
(S)-4-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin-1-yl]-ethyl}-1H-indol-5-ylmethyl)-oxazolidin-2-one
Show/Hide
|
C26H32N4O2
|
2
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
IC50 = 0.35 nM
|
|
|
|
CP0438472
|
N-methyl-2-phenyl-2-[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]ethanamine
Show/Hide
|
C26H33N7
|
2
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
IC50 = 0.9 nM
|
|
|
|
CP0382892
|
N-methyl-N-(3-methylbut-2-enyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H34N6
|
2
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
IC50 = 0.5 nM
|
|
|
|
CP0431656
|
(S)-2-Phenyl-2-({(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amino)-ethanol
Show/Hide
|
C25H30N6O
|
2
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
IC50 = 1.4 nM
|
|
|
|
CP0406721
|
N-[4-[2-[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]ethyl]phenyl]acetamide
Show/Hide
|
C27H33N7O
|
3
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
EC50 = 1.9 nM
|
|
|
| 3 |
IC50 = 1.3 nM
|
|
|
|
CP0406618
|
3-{(2R,3aR,6aR)-5-[2-(3-Fluoro-phenyl)-ethyl]-1-methyl-octahydro-pyrrolo[3,4-b]pyrrol-2-ylmethyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H29FN6
|
2
|
| 1 |
EC50 = 1.9 nM
|
|
|
| 2 |
IC50 = 1.2 nM
|
|
|
|
CP0497439
|
3-(2-Fluoro-3-{4-[2-(3-fluoro-phenyl)-propyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H30F2N6
|
2
|
| 1 |
EC50 = 1.9 nM
|
|
|
| 2 |
IC50 = 0.9 nM
|
|
|
|
CP0468110
|
3-{3-[4-(1H-Imidazol-2-ylmethyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C21H26N8
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
IC50 = 1.6 nM
|
|
|
|
CP0418953
|
3-[2-((R)-3-Benzyloxymethyl-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H27N5O
|
2
|
| 1 |
EC50 = 2.1 nM
|
|
|
| 2 |
IC50 = 2.3 nM
|
|
|
|
CP0375941
|
((R)-1-Phenyl-ethyl)-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C25H30N6
|
2
|
| 1 |
EC50 = 2.1 nM
|
|
|
| 2 |
IC50 = 0.72 nM
|
|
|
|
CP0381322
|
1-{1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C25H27N7O
|
2
|
| 1 |
EC50 = 2.2 nM
|
|
|
| 2 |
IC50 = 1.2 nM
|
|
|
|
CP0372894
|
3-(2-Pyrrolidin-1-yl-ethyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C16H19N5
|
4
|
| 1 |
EC50 = 2.3 nM
|
|
|
| 2 |
EC50 = 2.6 nM
|
|
|
| 3 |
IC50 = 3.1 nM
|
|
|
| 4 |
IC50 = 3.4 nM
|
|
|
|
CP0405279
|
1-Benzyl-4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazine-2-thione
Show/Hide
|
C24H26N6S
|
2
|
| 1 |
EC50 = 2.3 nM
|
|
|
| 2 |
IC50 = 0.8 nM
|
|
|
|
CP0378481
|
(S)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
|
C26H32N6O
|
2
|
| 1 |
EC50 = 2.6 nM
|
|
|
| 2 |
IC50 = 3.5 nM
|
|
|
|
CP0498039
|
3-{3-[4-Fluoro-4-(2-phenyl-propyl)-piperidin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C27H32FN5
|
2
|
| 1 |
EC50 = 2.6 nM
|
|
|
| 2 |
IC50 = 0.6 nM
|
|
|
|
CP0375959
|
N-[4-[[methyl-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]amino]methyl]phenyl]acetamide
Show/Hide
|
C29H37N7O
|
2
|
| 1 |
EC50 = 2.8 nM
|
|
|
| 2 |
IC50 = 0.6 nM
|
|
|
|
CP0375167
|
N-(furan-2-ylmethyl)-1-[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanamine
Show/Hide
|
C22H26N6O
|
2
|
| 1 |
EC50 = 2.8 nM
|
|
|
| 2 |
IC50 = 1.5 nM
|
|
|
|
CP0490477
|
3-[(2R,3aR,6aR)-5-(4-Fluoro-benzyl)-1-methyl-octahydro-pyrrolo[3,4-b]pyrrol-2-ylmethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H27FN6
|
2
|
| 1 |
EC50 = 2.9 nM
|
|
|
| 2 |
IC50 = 0.8 nM
|
|
|
|
CP0377606
|
N-[4-[(1S)-1-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methylamino]ethyl]phenyl]acetamide
Show/Hide
|
C29H37N7O
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
IC50 = 0.6 nM
|
|
|
|
CP0402357
|
Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-2-ylmethyl}-amine
Show/Hide
|
C25H30N6
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
IC50 = 0.8 nM
|
|
|
|
CP0503514
|
((S)-1-Phenyl-ethyl)-{(S)-1-[2-(5-[1,2,4]triazol-1-ylmethyl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C26H32N6
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
IC50 = 2.5 nM
|
|
|
|
CP0429012
|
(S)-4-[3-(2-{(S)-3-[(Benzyl-methyl-amino)-methyl]-pyrrolidin-1-yl}-ethyl)-1H-indol-5-ylmethyl]-3-methyl-oxazolidin-2-one
Show/Hide
|
C28H36N4O2
|
2
|
| 1 |
EC50 = 3.2 nM
|
|
|
| 2 |
IC50 = 1.7 nM
|
|
|
|
CP0392708
|
2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
2
|
| 1 |
EC50 = 3.4 nM
|
|
|
| 2 |
IC50 = 5.2 nM
|
|
|
|
CP0404804
|
N-methyl-N-(thiophen-2-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H30N6S
|
2
|
| 1 |
EC50 = 3.5 nM
|
|
|
| 2 |
IC50 = 4.3 nM
|
|
|
|
CP0041353
|
C-(3-{2-[(S)-3-(Benzylamino-methyl)-pyrrolidin-1-yl]-ethyl}-1H-indol-5-yl)-N-methyl-methanesulfonamide
Show/Hide
|
C24H32N4O2S
|
2
|
| 1 |
EC50 = 3.5 nM
|
|
|
| 2 |
IC50 = 1.1 nM
|
|
|
|
CP0453637
|
(S)-3-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
2
|
| 1 |
EC50 = 3.6 nM
|
|
|
| 2 |
IC50 = 2.1 nM
|
|
|
|
CP0395013
|
3-(2-Fluoro-3-{4-[2-(3-fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28F2N6
|
3
|
| 1 |
EC50 = 3.8 nM
|
|
|
| 2 |
EC50 = 4.4 nM
|
|
|
| 3 |
IC50 = 3.7 nM
|
|
|
|
CP0449242
|
3-{3-[4-(3-Phenyl-propyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H32N6
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
IC50 = 4.9 nM
|
|
|
|
CP0464807
|
Benzyl-{(R)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C24H28N6
|
2
|
| 1 |
EC50 = 4.1 nM
|
|
|
| 2 |
IC50 = 1.6 nM
|
|
|
|
CP0373772
|
N-methyl-N-(thiophen-3-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H30N6S
|
2
|
| 1 |
EC50 = 4.2 nM
|
|
|
| 2 |
IC50 = 1.5 nM
|
|
|
|
CP0449810
|
(1S)-N-methyl-1-phenyl-N-[[(3R)-1-[2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methyl]ethanamine
Show/Hide
|
C27H34N6
|
2
|
| 1 |
EC50 = 4.5 nM
|
|
|
| 2 |
IC50 = 0.7 nM
|
|
|
|
CP0376955
|
2-Phenyl-1'-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-[1,4']bipiperidinyl
Show/Hide
|
C29H36N6
|
2
|
| 1 |
EC50 = 4.7 nM
|
|
|
| 2 |
IC50 = 1.9 nM
|
|
|
|
CP0376850
|
Benzyl-{(S)-1-[2-(5-[1,2,4]triazol-1-ylmethyl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C25H30N6
|
2
|
| 1 |
EC50 = 4.9 nM
|
|
|
| 2 |
IC50 = 3.2 nM
|
|
|
|
CP0483511
|
N-[4-[[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]methyl]phenyl]acetamide
Show/Hide
|
C27H33N7O
|
2
|
| 1 |
EC50 = 5 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
|
CP0404530
|
3-(3-{4-Fluoro-4-[2-(3-fluoro-phenyl)-ethyl]-piperidin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H29F2N5
|
4
|
| 1 |
EC50 = 5 nM
|
|
|
| 2 |
EC50 = 5.1 nM
|
|
|
| 3 |
IC50 = 0.7 nM
|
|
|
| 4 |
IC50 = 0.75 nM
|
|
|
|
CP0504542
|
6-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H30N4O
|
1
|
| 1 |
EC50 = 5.012 nM
|
|
|
|
CP0377036
|
3-Phenyl-3-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
2
|
| 1 |
EC50 = 5.1 nM
|
|
|
| 2 |
IC50 = 5.5 nM
|
|
|
|
CP0500771
|
Benzyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine
Show/Hide
|
C26H32N6
|
2
|
| 1 |
EC50 = 5.6 nM
|
|
|
| 2 |
IC50 = 1.6 nM
|
|
|
|
CP0431438
|
(S)-4-(3-{3-[4-((R)-2-Hydroxy-1-phenyl-ethylamino)-piperidin-1-yl]-propyl}-1H-indol-5-ylmethyl)-oxazolidin-2-one
Show/Hide
|
C28H36N4O3
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
IC50 = 6.3 nM
|
|
|
|
CP0511371
|
N-[4-[[4-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperazin-1-yl]methyl]phenyl]acetamide
Show/Hide
|
C26H31N7O
|
2
|
| 1 |
EC50 = 6.1 nM
|
|
|
| 2 |
IC50 = 2.5 nM
|
|
|
|
CP0406224
|
1-[3-(5-imidazol-1-yl-1H-indol-3-yl)propyl]-N-[(1R)-1-phenylethyl]piperidin-4-amine
Show/Hide
|
C27H33N5
|
2
|
| 1 |
EC50 = 6.2 nM
|
|
|
| 2 |
IC50 = 4.2 nM
|
|
|
|
CP0327065
|
2-phenyl-N-[[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methyl]ethanamine
Show/Hide
|
C25H30N6
|
2
|
| 1 |
EC50 = 6.2 nM
|
|
|
| 2 |
IC50 = 2.6 nM
|
|
|
|
CP0509117
|
((R)-1-Methyl-2-phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C27H34N6
|
2
|
| 1 |
EC50 = 6.8 nM
|
|
|
| 2 |
IC50 = 5.5 nM
|
|
|
|
CP0404728
|
N-(furan-3-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C23H28N6O
|
2
|
| 1 |
EC50 = 7.1 nM
|
|
|
| 2 |
IC50 = 4.5 nM
|
|
|
|
CP0404431
|
(R)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-1-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
|
C26H32N6O
|
2
|
| 1 |
EC50 = 7.4 nM
|
|
|
| 2 |
IC50 = 4.1 nM
|
|
|
|
CP0453504
|
1-Benzyl-4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-2-one
Show/Hide
|
C24H26N6O
|
2
|
| 1 |
EC50 = 7.5 nM
|
|
|
| 2 |
IC50 = 6.6 nM
|
|
|
|
CP0440490
|
Benzyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C25H30N6
|
4
|
| 1 |
EC50 = 7.6 nM
|
|
|
| 2 |
EC50 = 8 nM
|
|
|
| 3 |
IC50 = 4.6 nM
|
|
|
| 4 |
IC50 = 4.8 nM
|
|
|
|
CP0380443
|
(R)-1-[2-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ol
Show/Hide
|
C16H19N5O
|
2
|
| 1 |
EC50 = 7.8 nM
|
|
|
| 2 |
IC50 = 9 nM
|
|
|
|
CP0383077
|
3-{3-[4-(2-Pyridin-3-yl-ethyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H29N7
|
2
|
| 1 |
EC50 = 7.8 nM
|
|
|
| 2 |
IC50 = 4.9 nM
|
|
|
|
CP0030068
|
N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine
Show/Hide
|
C15H19N5
|
2
|
| 1 |
EC50 = 8.4 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
|
CP0506684
|
(R)-2-Phenyl-2-({(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amino)-ethanol
Show/Hide
|
C25H30N6O
|
2
|
| 1 |
EC50 = 8.7 nM
|
|
|
| 2 |
IC50 = 8.3 nM
|
|
|
|
CP0377296
|
N-(furan-3-ylmethyl)-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H30N6O
|
2
|
| 1 |
EC50 = 8.9 nM
|
|
|
| 2 |
IC50 = 8.1 nM
|
|
|
|
CP0415184
|
N-[(1R)-1-(4-fluorophenyl)-2-methoxyethyl]-1-[3-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C28H35FN6O
|
2
|
| 1 |
EC50 = 8.9 nM
|
|
|
| 2 |
IC50 = 5 nM
|
|
|
|
CP0376530
|
[(2R)-2-phenyl-2-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethyl] carbamate
Show/Hide
|
C27H33N7O2
|
2
|
| 1 |
EC50 = 9.3 nM
|
|
|
| 2 |
IC50 = 4.7 nM
|
|
|
|
CP0442688
|
N-(pyridin-4-ylmethyl)-1-[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanamine
Show/Hide
|
C23H27N7
|
2
|
| 1 |
EC50 = 9.5 nM
|
|
|
| 2 |
IC50 = 8.5 nM
|
|
|
|
CP0376627
|
(R)-2-(Methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amino)-2-phenyl-ethanol
Show/Hide
|
C27H34N6O
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
IC50 = 4.5 nM
|
|
|
|
CP0447958
|
N-[4-[[[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methylamino]methyl]phenyl]acetamide
Show/Hide
|
C26H31N7O
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
IC50 = 12 nM
|
|
|
|
CP0375911
|
Benzyl-methyl-{(S)-1-[2-(5-[1,2,4]triazol-1-ylmethyl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C26H32N6
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
IC50 = 7.7 nM
|
|
|
|
CP0410759
|
5-[1,2,4]Triazol-4-yl-3-{3-[4-(4-trifluoromethyl-benzyl)-piperazin-1-yl]-propyl}-1H-indole
Show/Hide
|
C25H27F3N6
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
IC50 = 5.2 nM
|
|
|
|
CP0005653
|
(3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide
Show/Hide
|
C14H21N3O2S
|
6
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
EC50 = 14 nM
|
|
|
| 3 |
EC50 = 16 nM
|
|
|
| 4 |
IC50 = 5 nM
|
|
|
| 5 |
IC50 = 6.7 nM
|
|
|
| 6 |
IC50 = 6.8 nM
|
|
|
|
CP0392444
|
N-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C25H30N6O2S
|
2
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
IC50 = 6.2 nM
|
|
|
|
CP0420958
|
((S)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C26H32N6
|
2
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
IC50 = 0.6 nM
|
|
|
|
CP0376999
|
N-(pyridin-4-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C24H29N7
|
2
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
IC50 = 24 nM
|
|
|
|
CP0845065
|
(R)-1-{(S)-1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-indan-2-ol
Show/Hide
|
C27H32N6O
|
2
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
IC50 = 6.6 nM
|
|
|
|
CP0430871
|
(R)-3-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
2
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
IC50 = 8.3 nM
|
|
|
|
CP0392733
|
(1R,2R)-1-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
|
C27H34N6O
|
2
|
| 1 |
EC50 = 15 nM
|
|
|
| 2 |
IC50 = 11 nM
|
|
|
|
CP0409861
|
(R)-N-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propionamide
Show/Hide
|
C27H33N7O
|
2
|
| 1 |
EC50 = 15 nM
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| 2 |
IC50 = 7.6 nM
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CP0429000
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3-[2-((R)-3-Benzyloxy-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H25N5O
|
2
|
| 1 |
EC50 = 15 nM
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| 2 |
IC50 = 6.3 nM
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CP0487478
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3-{2,2-Difluoro-3-[4-(2-phenyl-propyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H30F2N6
|
2
|
| 1 |
EC50 = 16 nM
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| 2 |
IC50 = 6.2 nM
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CP0383146
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Benzyl-{1-[2-fluoro-3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-methyl-amine
Show/Hide
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C26H31FN6
|
2
|
| 1 |
EC50 = 18 nM
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| 2 |
IC50 = 5.4 nM
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CP0420929
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((R)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-1-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
|
C26H32N6
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2
|
| 1 |
EC50 = 18 nM
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| 2 |
IC50 = 18 nM
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CP0406242
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N-(2,3-dihydro-1H-inden-1-yl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
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C27H32N6
|
2
|
| 1 |
EC50 = 25 nM
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| 2 |
IC50 = 8.9 nM
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CP0409378
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(1R,2S)-1-Phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-2-ol
Show/Hide
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C27H34N6O
|
2
|
| 1 |
EC50 = 30 nM
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| 2 |
IC50 = 7.6 nM
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CP0376560
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3-[2-((S)-3-Benzyloxy-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H25N5O
|
2
|
| 1 |
EC50 = 31 nM
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| 2 |
IC50 = 20 nM
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CP0409608
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(R)-2-Phenyl-2-{1-[3-(5-[1,2,4]triazol-1-ylmethyl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-ethanol
Show/Hide
|
C27H34N6O
|
2
|
| 1 |
EC50 = 32 nM
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| 2 |
IC50 = 23 nM
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CP0468024
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3-[3-(4-Benzyloxy-piperidin-1-yl)-2,2-difluoro-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C25H27F2N5O
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2
|
| 1 |
EC50 = 34 nM
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| 2 |
IC50 = 8.5 nM
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CP0498565
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3-(2,2-Difluoro-3-{4-[2-(3-fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H27F3N6
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2
|
| 1 |
EC50 = 35 nM
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| 2 |
IC50 = 15 nM
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CP0470678
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3-[3-(4-Methyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C18H24N6
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4
|
| 1 |
EC50 = 53 nM
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| 2 |
EC50 = 54 nM
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| 3 |
IC50 = 33 nM
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| 4 |
IC50 = 35 nM
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CP0395210
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3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C17H22N6
|
4
|
| 1 |
EC50 = 80 nM
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| 2 |
EC50 = 105 nM
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| 3 |
IC50 = 134 nM
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| 4 |
IC50 = 140 nM
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CP0504140
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4-Benzyl-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C25H29N5O
|
2
|
| 1 |
ED50 = 0.25 nM
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| 2 |
IC50 = 0.1 nM
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CP0441753
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4-(3,3-Dimethyl-piperidin-1-ylmethyl)-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C26H38N6O
|
2
|
| 1 |
ED50 = 0.9 nM
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| 2 |
IC50 = 0.65 nM
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CP0494812
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4-[(Cyclopropylmethyl-methyl-amino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C24H34N6O
|
2
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| 1 |
ED50 = 1.1 nM
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| 2 |
IC50 = 1.35 nM
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CP0405735
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4-[(Cyclohexylmethyl-methyl-amino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
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C27H40N6O
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2
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| 1 |
ED50 = 1.4 nM
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| 2 |
IC50 = 1.2 nM
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CP0424644
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4-{[(2,2-Dimethyl-propyl)-methyl-amino]-methyl}-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C25H38N6O
|
2
|
| 1 |
ED50 = 1.6 nM
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| 2 |
IC50 = 1.8 nM
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CP0511195
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4-[(Isobutyl-methyl-amino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C24H36N6O
|
2
|
| 1 |
ED50 = 1.7 nM
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| 2 |
IC50 = 0.65 nM
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CP0496894
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4-(Benzylamino-methyl)-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C26H32N6O
|
2
|
| 1 |
ED50 = 2.2 nM
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| 2 |
IC50 = 0.45 nM
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CP0395348
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4-{[(Pyridin-2-ylmethyl)-amino]-methyl}-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C25H31N7O
|
2
|
| 1 |
ED50 = 3.2 nM
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| 2 |
IC50 = 3.2 nM
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CP0405114
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4-{[Methyl-(2-methyl-benzyl)-amino]-methyl}-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C28H36N6O
|
2
|
| 1 |
ED50 = 3.7 nM
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| 2 |
IC50 = 1.3 nM
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CP0514196
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4-[(Benzyl-methyl-amino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C27H34N6O
|
2
|
| 1 |
ED50 = 3.8 nM
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| 2 |
IC50 = 1.2 nM
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CP0401299
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tert-butyl N-[[4-hydroxy-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]carbamate
Show/Hide
|
C24H34N6O3
|
2
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| 1 |
ED50 = 9.7 nM
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| 2 |
IC50 = 21 nM
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CP0376344
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N-[4-[[[4-hydroxy-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methylamino]methyl]phenyl]acetamide
Show/Hide
|
C28H35N7O2
|
2
|
| 1 |
ED50 = 14 nM
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| 2 |
IC50 = 11 nM
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CP0395010
|
3-{3-[4-Fluoro-4-(2-fluoro-benzyl)-piperidin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H27F2N5
|
1
|
| 1 |
IC50 = 0.1 nM
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CP0498564
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3-{3-[4-Fluoro-4-(3-fluoro-benzyl)-piperidin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H27F2N5
|
1
|
| 1 |
IC50 = 0.4 nM
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CP0446541
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3-(3-{4-Fluoro-4-[2-(2-fluoro-phenyl)-ethyl]-piperidin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H29F2N5
|
1
|
| 1 |
IC50 = 0.8 nM
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CP0448243
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3-[2-((S)-2-Benzyloxymethyl-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
IC50 = 0.81 nM
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CP0403501
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Benzyl-[(3R,5R)-5-(5-imidazol-1-yl-1H-indol-3-ylmethyl)-1-methyl-pyrrolidin-3-ylmethyl]-methyl-amine
Show/Hide
|
C26H31N5
|
1
|
| 1 |
IC50 = 0.9 nM
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CP0421330
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3-(3-{4-Fluoro-4-[2-(4-fluoro-phenyl)-ethyl]-piperidin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H29F2N5
|
1
|
| 1 |
IC50 = 1 nM
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CP0504688
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3-(2-Fluoro-3-{4-[2-(2-fluoro-phenyl)-propyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H30F2N6
|
1
|
| 1 |
IC50 = 1 nM
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CP0395405
|
3-{3-[4-(1-Phenyl-ethyl)-piperazin-1-yl]-propyl}-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H30N6
|
1
|
| 1 |
IC50 = 1 nM
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CP0496271
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N-benzyl-N-[[(3R)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methyl]acetamide
Show/Hide
|
C26H30N6O
|
1
|
| 1 |
IC50 = 1.1 nM
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CP0502206
|
3-(2-Azetidin-1-yl-ethyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C15H17N5
|
1
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| 1 |
IC50 = 1.1 nM
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CP0406225
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((R)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine
Show/Hide
|
C27H34N6
|
1
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| 1 |
IC50 = 1.4 nM
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CP0502071
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N-[(1R)-1-(4-fluorophenyl)-2-methoxyethyl]-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C27H33FN6O
|
1
|
| 1 |
IC50 = 1.4 nM
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CP0454869
|
3-[3-(4-Phenyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C23H26N6
|
1
|
| 1 |
IC50 = 1.4 nM
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CP0430876
|
N-[4-[(1R)-1-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methylamino]ethyl]phenyl]acetamide
Show/Hide
|
C29H37N7O
|
1
|
| 1 |
IC50 = 1.5 nM
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CP0499480
|
(R)-N*2*,N*2*-Dimethyl-1-phenyl-N*1*-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-ethane-1,2-diamine
Show/Hide
|
C28H37N7
|
1
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| 1 |
IC50 = 1.5 nM
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CP0499516
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N-methyl-N-[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C25H30N6O2S
|
1
|
| 1 |
IC50 = 1.5 nM
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CP0479230
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N-methyl-N-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C26H32N6O2S
|
1
|
| 1 |
IC50 = 1.6 nM
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CP0504202
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N-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methyl]pyridin-2-amine
Show/Hide
|
C24H29N7
|
1
|
| 1 |
IC50 = 1.7 nM
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CP0393241
|
3-(2,2-Difluoro-3-{4-[2-(4-fluoro-phenyl)-propyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H29F3N6
|
1
|
| 1 |
IC50 = 1.8 nM
|
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CP0422756
|
1-(4-Benzyl-piperazin-1-yl)-3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propan-2-ol
Show/Hide
|
C24H28N6O
|
1
|
| 1 |
IC50 = 1.8 nM
|
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CP0415642
|
3-[3-(4-Fluoro-4-phenethyl-piperidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C26H30FN5
|
1
|
| 1 |
IC50 = 2 nM
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CP0501149
|
(3S,4S)-N-benzyl-3-fluoro-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C26H31FN6
|
1
|
| 1 |
IC50 = 2.1 nM
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CP0511265
|
3-[3-((R)-3-Benzyloxymethyl-pyrrolidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H29N5O
|
1
|
| 1 |
IC50 = 2.1 nM
|
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CP0395040
|
Benzyl-{(3R,4S)-3-fluoro-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-methyl-amine
Show/Hide
|
C26H31FN6
|
2
|
| 1 |
IC50 = 2.2 nM
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| 2 |
IC50 = 12 nM
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CP0405595
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N-methyl-N-(4-methylpent-3-enyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
|
C25H36N6
|
1
|
| 1 |
IC50 = 2.6 nM
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CP0460183
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Benzyl-[(3S,5R)-5-(5-imidazol-1-yl-1H-indol-3-ylmethyl)-1-methyl-pyrrolidin-3-ylmethyl]-cyanamide
Show/Hide
|
C26H28N6
|
1
|
| 1 |
IC50 = 3.3 nM
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CP0483398
|
(S)-2-Phenyl-2-({1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amino)-ethanol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 3.4 nM
|
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CP0374965
|
N-(pyridin-2-ylmethyl)-1-[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanamine
Show/Hide
|
C23H27N7
|
1
|
| 1 |
IC50 = 3.6 nM
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CP0467572
|
N-(pyridin-3-ylmethyl)-1-[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanamine
Show/Hide
|
C23H27N7
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
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CP0448062
|
4-[(2-Methyl-benzylamino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 4 nM
|
|
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CP0392525
|
N-[4-[[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]methylamino]methyl]phenyl]acetamide
Show/Hide
|
C28H35N7O
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0511172
|
Benzyl-methyl-{(S)-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
|
C26H32N6
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
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CP0415084
|
(S)-2-(Methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amino)-2-phenyl-ethanol
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
IC50 = 4.3 nM
|
|
|
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CP0449271
|
((S)-1-Phenyl-ethyl)-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine
Show/Hide
|
C27H34N6
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0437770
|
4-[(Cyclopropylmethyl-amino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
|
C23H32N6O
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
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CP0496764
|
3-(2-Fluoro-3-{4-[2-(2-fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28F2N6
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0509615
|
(3S,4S)-3-fluoro-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-amine
Show/Hide
|
C26H28F4N6
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0468111
|
1-Phenethyl-4-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-2-one
Show/Hide
|
C25H28N6O
|
1
|
| 1 |
IC50 = 5.2 nM
|
|
|
|
CP0410106
|
3-(2-Fluoro-3-{4-[2-(4-fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
|
C25H28F2N6
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0514551
|
N-[4-[2-[methyl-[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethyl]phenyl]acetamide
Show/Hide
|
C29H37N7O
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0462723
|
3-[(2S)-2-fluoro-3-[4-[2-(3-fluorophenyl)ethyl]piperazin-1-yl]propyl]-5-(1,2,4-triazol-4-yl)-1H-indole
Show/Hide
|
C25H28F2N6
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0393197
|
1-Methyl-3-phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-urea
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C27H33N7O
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1
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| 1 |
IC50 = 5.9 nM
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CP0404430
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(R)-2-Phenyl-2-({1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amino)-ethanol
Show/Hide
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C27H34N6O
|
1
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| 1 |
IC50 = 5.9 nM
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CP0480630
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(R)-2-(Methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amino)-2-phenyl-ethanol
Show/Hide
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C28H36N6O
|
1
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| 1 |
IC50 = 6 nM
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CP0463038
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3-[2-Fluoro-3-(4-phenethyl-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
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C25H29FN6
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1
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| 1 |
IC50 = 6.8 nM
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CP0453397
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3-[3-(4-{2-[4-(3-Methyl-[1,2,4]oxadiazol-5-yl)-phenyl]-ethyl}-piperazin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C28H32N8O
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1
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| 1 |
IC50 = 6.9 nM
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CP0502188
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4-[(2,2-Dimethyl-propylamino)-methyl]-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ol
Show/Hide
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C24H36N6O
|
1
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| 1 |
IC50 = 7.3 nM
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CP0460829
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(4-Methanesulfonyl-benzyl)-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine
Show/Hide
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C28H36N6O2S
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1
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| 1 |
IC50 = 8.1 nM
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CP0542475
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3-(3-Morpholin-4-yl-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
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C17H21N5O
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1
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| 1 |
IC50 = 8.8 nM
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CP0447863
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N-[[(3S)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methyl]aniline
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C23H26N6
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1
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| 1 |
IC50 = 9.1 nM
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CP0503355
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N-(furan-2-ylmethyl)-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
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C24H30N6O
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1
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| 1 |
IC50 = 9.3 nM
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CP0415643
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(3R,4S)-3-fluoro-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-amine
Show/Hide
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C27H30F4N6
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1
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| 1 |
IC50 = 9.3 nM
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CP0437805
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But-2-ynyl-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
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C23H30N6
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1
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| 1 |
IC50 = 9.8 nM
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CP0502201
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1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamine
Show/Hide
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C18H24N6
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1
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| 1 |
IC50 = 12 nM
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CP0504203
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N-[4-[2-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethyl]phenyl]acetamide
Show/Hide
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C28H35N7O
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1
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| 1 |
IC50 = 12 nM
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CP0409041
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(1S,2R)-1-Phenyl-2-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-propan-1-ol
Show/Hide
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C27H34N6O
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1
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| 1 |
IC50 = 12 nM
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CP0330418
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Benzyl-{(3S,4R)-3-fluoro-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-methyl-amine
Show/Hide
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C26H31FN6
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1
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| 1 |
IC50 = 13 nM
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CP0468023
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(3R,4S)-3-fluoro-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-amine
Show/Hide
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C26H28F4N6
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1
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| 1 |
IC50 = 13 nM
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CP0497734
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(3S,4S)-3-fluoro-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-N-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-amine
Show/Hide
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C27H30F4N6
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1
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| 1 |
IC50 = 13 nM
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CP0483598
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N-(pyridin-2-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
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C24H29N7
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1
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| 1 |
IC50 = 14 nM
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CP0377018
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N-[(2R)-2-phenyl-2-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethyl]methanesulfonamide
Show/Hide
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C27H35N7O2S
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1
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| 1 |
IC50 = 15 nM
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CP0420921
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4-Acetylamino-N-methyl-N-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-benzamide
Show/Hide
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C29H35N7O2
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1
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| 1 |
IC50 = 17 nM
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CP0509931
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Allyl-{(S)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-ylmethyl}-amine
Show/Hide
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C20H26N6
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1
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| 1 |
IC50 = 17 nM
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CP0420959
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(4-Methanesulfonyl-benzyl)-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
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C27H34N6O2S
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1
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| 1 |
IC50 = 18 nM
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CP0508887
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1-Methyl-3-phenyl-1-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-urea
Show/Hide
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C26H31N7O
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1
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| 1 |
IC50 = 18 nM
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CP0409363
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N-[4-[[methyl-[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]methyl]phenyl]acetamide
Show/Hide
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C28H35N7O
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1
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| 1 |
IC50 = 19 nM
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CP0464787
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Allyl-methyl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-amine
Show/Hide
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C22H30N6
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1
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| 1 |
IC50 = 20 nM
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CP0420915
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N-(cyclopropylmethyl)-N-methyl-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
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C23H32N6
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1
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| 1 |
IC50 = 22 nM
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CP0487078
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3-(3-Piperidin-1-yl-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C18H23N5
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1
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| 1 |
IC50 = 24 nM
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CP0374963
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[(3R)-1-[2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethyl]pyrrolidin-3-yl]methanol
Show/Hide
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C17H21N5O
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1
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| 1 |
IC50 = 26 nM
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CP0565410
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N-[4-[(1R)-1-[[1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-yl]amino]ethyl]phenyl]acetamide
Show/Hide
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C28H35N7O
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1
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| 1 |
IC50 = 29 nM
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CP0431094
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3-[3-(4-Benzyloxy-piperidin-1-yl)-2-fluoro-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C25H28FN5O
|
1
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| 1 |
IC50 = 30 nM
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CP0383076
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3-(3-Piperazin-1-yl-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C17H22N6
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1
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| 1 |
IC50 = 31 nM
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CP0504032
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N-(pyridin-3-ylmethyl)-1-[3-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]piperidin-4-amine
Show/Hide
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C24H29N7
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1
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| 1 |
IC50 = 35 nM
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CP0497440
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Benzyl-{1-[2,2-difluoro-3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-yl}-methyl-amine
Show/Hide
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C26H30F2N6
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1
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| 1 |
IC50 = 35 nM
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CP0499517
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(S)-1-{(R)-1-[3-(5-[1,2,4]Triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylamino}-indan-2-ol
Show/Hide
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C27H32N6O
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1
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| 1 |
IC50 = 37 nM
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CP0418379
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Benzyl-methyl-{(R)-1-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-pyrrolidin-3-yl}-amine
Show/Hide
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C24H28N6
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2
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| 1 |
IC50 = 37 nM
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| 2 |
IC50 = 38 nM
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CP0457220
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N-methyl-1-[3-[3-[4-[[(1R)-1-phenylethyl]amino]piperidin-1-yl]propyl]-1H-indol-5-yl]methanesulfonamide
Show/Hide
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C26H36N4O2S
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1
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| 1 |
IC50 = 43 nM
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CP0504689
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3-[2,2-Difluoro-3-(4-phenethyl-piperidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C26H29F2N5
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1
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| 1 |
IC50 = 56 nM
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CP0422757
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3-[3-(4-Benzyl-piperidin-1-yl)-2,2-difluoro-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C25H27F2N5
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1
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| 1 |
IC50 = 78 nM
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CP0392837
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3-[2-((R)-2-Benzyloxymethyl-pyrrolidin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C24H27N5O
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1
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| 1 |
IC50 = 95 nM
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CP0453021
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4-Benzyl-1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperazin-2-one
Show/Hide
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C24H26N6O
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1
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| 1 |
IC50 = 173 nM
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CP0425067
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3-(2-Piperidin-1-yl-ethyl)-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C17H21N5
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1
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| 1 |
IC50 = 200 nM
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CP0529312
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3-[4-(4-Methyl-piperazin-1-yl)-butyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C19H26N6
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1
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| 1 |
IC50 = 210 nM
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CP0055933
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3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
Show/Hide
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C22H22FN3O3
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2
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| 1 |
IC50 = 260 nM
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| 2 |
IC50 = 270 nM
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CP0460034
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3-[2,2-Difluoro-3-(4-phenoxymethyl-piperidin-1-yl)-propyl]-5-[1,2,4]triazol-4-yl-1H-indole
Show/Hide
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C25H27F2N5O
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1
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| 1 |
IC50 = 280 nM
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CP0068074
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazine-3-carboxamide
Show/Hide
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C27H28N6O2
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3
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| 1 |
Kd = 0.1698 nM
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| 2 |
Ki = 0.1 nM
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| 3 |
Ki = 0.1585 nM
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CP0216068
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N-(cyclopropylmethyl)-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C31H34N6O2
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1
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| 1 |
Ki = 0.01995 nM
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CP0104145
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N-cyclopropyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C30H32N6O2
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1
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| 1 |
Ki = 0.03981 nM
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CP0283739
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8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H26N4O2
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1
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| 1 |
Ki = 0.05012 nM
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CP0406080
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1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C26H30N4O
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1
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| 1 |
Ki = 0.07943 nM
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CP0064904
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,2-d][1,4]oxazine
Show/Hide
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C26H27N5O
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1
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| 1 |
Ki = 0.1 nM
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CP0096953
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1-(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)ethanone
Show/Hide
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C28H29N5O2
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1
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| 1 |
Ki = 0.1 nM
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CP0126585
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4-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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2
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| 1 |
Ki = 0.1 nM
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| 2 |
Ki = 0.3162 nM
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CP0260884
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N-cyclobutyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C31H34N6O2
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1
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| 1 |
Ki = 0.1 nM
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CP0270386
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4-methyl-8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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2
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| 1 |
Ki = 0.1 nM
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| 2 |
Ki = 0.3162 nM
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CP0406079
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5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
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C25H28N4O
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1
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| 1 |
Ki = 0.1 nM
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CP0036547
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazine
Show/Hide
|
C26H27N5O
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1
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| 1 |
Ki = 0.1259 nM
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CP0041018
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6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]tetrazolo[1,5-d][1,4]oxazine
Show/Hide
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C24H25N7O
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1
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| 1 |
Ki = 0.1259 nM
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CP0068072
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3-methyl-6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b][1,2,3]triazolo[1,5-d][1,4]oxazine
Show/Hide
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C26H28N6O
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1
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| 1 |
Ki = 0.1259 nM
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CP0069977
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2-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[2,1-c][1,4]benzoxazine
Show/Hide
|
C27H29N5O
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1
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| 1 |
Ki = 0.1259 nM
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CP0096954
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N-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
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C28H30N6O2
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1
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| 1 |
Ki = 0.1259 nM
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CP0233604
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6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-2-(trifluoromethyl)-4H-imidazo[2,1-c][1,4]benzoxazine
Show/Hide
|
C27H26F3N5O
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1
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| 1 |
Ki = 0.1259 nM
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CP0454396
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5-[2-[(2R)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
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C27H29FN4O
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1
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| 1 |
Ki = 0.1259 nM
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CP0502083
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5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1H-quinolin-2-one
Show/Hide
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C25H26N4O
|
1
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| 1 |
Ki = 0.1259 nM
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CP0040401
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N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]methanesulfonamide
Show/Hide
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C23H28N4O2S
|
1
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| 1 |
Ki = 0.1259 nM
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CP0866064
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Ethyl(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)carbamate
Show/Hide
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C25H30N4O2
|
1
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| 1 |
Ki = 0.1259 nM
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CP0218850
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6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H26N4O2
|
3
|
| 1 |
Ki = 0.1585 nM
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| 2 |
Ki = 0.1995 nM
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| 3 |
Ki = 0.5012 nM
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CP0412307
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6-[2-[4-(2,2-dimethyl-3H-1-benzofuran-7-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H29N3O3
|
1
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| 1 |
Ki = 0.1585 nM
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CP0422492
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6-[2-[4-(7-chloro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25ClN4O2
|
1
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| 1 |
Ki = 0.1585 nM
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CP0036194
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1,2-dimethyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[2,1-c][1,4]benzoxazine
Show/Hide
|
C28H31N5O
|
1
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| 1 |
Ki = 0.1585 nM
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CP0068073
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N,N-dimethyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
|
C29H32N6O2
|
1
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| 1 |
Ki = 0.1585 nM
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CP0068076
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(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)(piperidin-1-yl)methanone
Show/Hide
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C32H36N6O2
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0089790
|
(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)(pyrrolidin-1-yl)methanone
Show/Hide
|
C31H34N6O2
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0096951
|
(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)(morpholino)methanone
Show/Hide
|
C31H34N6O3
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0097108
|
6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-N-propan-2-yl-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
|
C30H34N6O2
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0126586
|
1-methyl-6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]oxazine
Show/Hide
|
C26H28N6O
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0332161
|
N-cyclopentyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide
Show/Hide
|
C32H36N6O2
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0040402
|
3-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-1,3-oxazolidin-2-one
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0081200
|
1-ethyl-3-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]urea
Show/Hide
|
C25H31N5O
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0688933
|
2-Methyl-5-(4-{2-[3-(1H-pyrazol-1-yl)phenyl]ethyl}-1-piperazinyl)quinoline
Show/Hide
|
C25H27N5
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0845520
|
2-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)propanamide
Show/Hide
|
C26H32N4O
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0845528
|
N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-N'-propylurea
Show/Hide
|
C26H33N5O
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0845559
|
3-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Benzamide
Show/Hide
|
C30H32N4O2
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0397086
|
6-[2-[4-(2-methyl-1H-indol-4-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0403060
|
6-[2-[4-(7-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25FN4O2
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0412277
|
6-[2-[4-(8-chloro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25ClN4O2
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0422490
|
8-fluoro-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25FN4O2
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0374349
|
2-methyl-5-[2-[4-[[3-(1-methylpiperidin-4-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C30H39N3O
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0226445
|
azetidin-1-yl-[6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazin-3-yl]methanone
Show/Hide
|
C30H32N6O2
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0040404
|
1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone
Show/Hide
|
C25H29N5O
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0648465
|
N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-pyrazine Carboxamide
Show/Hide
|
C27H28N6O
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0845556
|
N-(2-Fluorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea
Show/Hide
|
C29H30FN5O
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0864963
|
N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-propanamide
Show/Hide
|
C25H30N4O
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0439878
|
5-[2-[4-(1H-benzimidazol-4-ylmethyl)piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0398938
|
6-[2-(4-quinolin-8-ylpiperazin-1-yl)ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0422489
|
6-[2-(4-isoquinolin-1-ylpiperazin-1-yl)ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0465757
|
7-fluoro-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25FN4O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0040405
|
N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]acetamide
Show/Hide
|
C24H28N4O
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0648464
|
Methyl(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)carbamate
Show/Hide
|
C24H28N4O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0845521
|
2-Fluoro-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)Benzamide
Show/Hide
|
C29H29FN4O
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0845523
|
4-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H29N5OS
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0845558
|
3-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-tetrahydro-2H-1,3-oxazin-2-one
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0855722
|
N-(1,1-Dimethylethyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea
Show/Hide
|
C27H35N5O
|
1
|
| 1 |
Ki = 0.2512 nM
|
|
|
|
CP0377437
|
6-[2-[4-(8-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25FN4O2
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0397085
|
6-[2-[4-(2-methylquinazolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C23H25N5O2
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0403061
|
6-[2-[3-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0089820
|
1-(6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazin-3-yl)ethanone O-methyl oxime
Show/Hide
|
C29H32N6O2
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0124306
|
ethyl 6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxylate
Show/Hide
|
C29H31N5O3
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0040398
|
N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]benzamide
Show/Hide
|
C29H30N4O
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0116805
|
1-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-3-phenylurea
Show/Hide
|
C29H31N5O
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0845522
|
1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-tetrahydro-2(1H)-pyrimidinone
Show/Hide
|
C26H31N5O
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0845526
|
2,2-Dimethyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)propanamide
Show/Hide
|
C27H34N4O
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0845529
|
N-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Acetamide
Show/Hide
|
C25H30N4O
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0855716
|
3-Fluoro-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)Benzamide
Show/Hide
|
C29H29FN4O
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0372020
|
8-fluoro-6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H28FN3O3
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0146099
|
8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C26H29FN4O3
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0377439
|
4-ethyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0397084
|
6-[2-[4-(2,7-dimethylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0427664
|
5-fluoro-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25FN4O2
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0502082
|
6-fluoro-1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C26H27FN4O
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0040416
|
2-methyl-N-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C27H29N5OS
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0845530
|
4-Fluoro-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-phenyl)Benzamide
Show/Hide
|
C29H29FN4O
|
1
|
| 1 |
Ki = 0.3981 nM
|
|
|
|
CP0146095
|
4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0177522
|
5-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C26H29FN4O3
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0398939
|
6-[2-[(2R)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0173138
|
N-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]methanesulfonamide
Show/Hide
|
C25H31N3O3S
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0461521
|
2-methyl-5-[2-[4-[[3-(4-methylpiperazin-1-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0502072
|
5-[2-[2,2-dimethyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
|
C28H32N4O
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0861905
|
N-(4-Fluorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea
Show/Hide
|
C29H30FN5O
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0861908
|
3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline
Show/Hide
|
C22H26N4
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0900503
|
4-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Benzamide
Show/Hide
|
C30H32N4O2
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
|
CP0382051
|
2-methyl-5-[2-[4-[[3-(4-methyl-1,4-diazepan-1-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C30H40N4O
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0453856
|
2-methyl-5-[2-[4-[[3-[(3R)-3-methylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0845557
|
2-(Methyloxy)-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]-ethyl}phenyl)Benzamide
Show/Hide
|
C30H32N4O2
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0855718
|
N-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-1-propanesulfonamide
Show/Hide
|
C25H32N4O2S
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0861892
|
N-(3-Fluorophenyl)-N'-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)urea
Show/Hide
|
C29H30FN5O
|
1
|
| 1 |
Ki = 0.631 nM
|
|
|
|
CP0371946
|
5-fluoro-6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H28FN3O3
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0079263
|
2-methyl-5-[2-[4-(quinolin-8-ylmethyl)piperazin-1-yl]ethoxy]quinoline
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0461527
|
5-[2-[4-[[3-[(3S,5R)-3,5-dimethylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C30H40N4O
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0374866
|
(8R)-8-[3-phenylpropyl(propyl)amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C25H30N2O
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0146096
|
4-ethyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C27H32N4O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0214664
|
2-(dimethylamino)-N-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]acetamide
Show/Hide
|
C28H36N4O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0377813
|
2-methyl-5-[2-[4-[[3-[(3S)-3-methylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0377822
|
2-methyl-5-[2-[4-[(3-piperidin-1-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C29H37N3O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0417819
|
5-[2-[4-[[3-[(2S,5R)-2,5-dimethylpiperazin-1-yl]phenyl]methyl]piperidin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C30H40N4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0450459
|
2-methyl-5-[2-[4-[(3-pyridin-4-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C29H31N3O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0406077
|
1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C27H32N4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0177439
|
4-ethyl-5-fluoro-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C27H31FN4O3
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0388729
|
2-methyl-5-[2-[4-[(3-piperidin-4-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C29H37N3O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0406075
|
5-[2-[(2S)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
|
C27H29FN4O
|
1
|
| 1 |
Ki = 1.259 nM
|
|
|
|
CP0341517
|
N,N-dimethyl-2-(6-pyridin-3-ylindol-1-yl)ethanamine
Show/Hide
|
C17H19N3
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0152118
|
6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0399848
|
2-amino-4-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]phenol
Show/Hide
|
C23H28N4O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0873316
|
4-ethyl-6-((1-(2-(2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C28H33N3O3
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0377438
|
6-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0388749
|
(2S,6R)-2,6-dimethyl-4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]morpholine
Show/Hide
|
C30H39N3O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0845527
|
1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2,5-pyrrolidinedione
Show/Hide
|
C26H28N4O2
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0509509
|
(8R)-8-(dimethylamino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C15H18N2O
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0496867
|
2-methyl-5-[2-[4-[(4-methyl-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]quinoline
Show/Hide
|
C24H28N4O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0216724
|
6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-4-phenethyl-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C33H36N4O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0344597
|
6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-4-propyl-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C28H34N4O3
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0461524
|
2-methyl-5-[2-[4-[(3-pyridin-3-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C29H31N3O
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0233605
|
6-(2-(4-(2-methylquinolin-5-yl)piperazin-1-yl)ethyl)-4H-benzo[b]imidazo[1,5-d][1,4]oxazine-3-carbonitrile
Show/Hide
|
C27H26N6O
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0479139
|
1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0505428
|
5-[2-[4-(7-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,6-dimethylquinolin-2-one
Show/Hide
|
C27H29FN4O
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0378553
|
8-[(3-Phenyl-propyl)-propyl-amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C25H30N2O
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0424195
|
8-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C22H26N2OS
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0040186
|
4-[1-(2-Dimethylamino-ethyl)-1H-indol-6-yl]-tetrahydro-thiopyran-4-ol
Show/Hide
|
C17H24N2OS
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0392682
|
N-[3-(2-methoxyphenyl)propyl]-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C25H32N2O
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0513848
|
6-[[1-[2-(6-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H28FN3O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0436208
|
2-methyl-5-[2-[4-(quinolin-5-ylmethyl)piperazin-1-yl]ethoxy]quinoline
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0436211
|
5-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]quinazoline
Show/Hide
|
C25H27N5O
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0729034
|
4-methyl-6-((1-(2-(2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C27H31N3O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0880810
|
4-isobutyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C29H36N4O3
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0377823
|
4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]morpholine
Show/Hide
|
C28H35N3O2
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0388728
|
2-methyl-5-[2-[4-[(3-pyrrolidin-1-ylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C28H35N3O
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0406078
|
6-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1H-quinolin-2-one
Show/Hide
|
C26H28N4O
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0502075
|
1,6-dimethyl-5-[2-[(2R)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C28H32N4O
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0392154
|
8-(Phenethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C24H28N2O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0372019
|
7-fluoro-6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H28FN3O3
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0403124
|
5-[2-[4-(1H-indol-7-ylmethyl)piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0439874
|
5-[2-[4-(1H-indol-5-ylmethyl)piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0091710
|
4-butyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C29H36N4O3
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0382035
|
2-methyl-5-[2-[4-[[3-(1-methylsulfonylpiperidin-4-yl)phenyl]methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C30H39N3O3S
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0378377
|
8-{[3-(2-Methoxy-phenyl)-propyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C26H32N2O2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0295921
|
4-[1-(2-Dimethylamino-ethyl)-1H-indol-6-yl]-tetrahydro-pyran-4-ol
Show/Hide
|
C17H24N2O2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0378949
|
N,N-dimethyl-2-[6-(oxan-4-yl)indol-1-yl]ethanamine
Show/Hide
|
C17H24N2O
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0404673
|
5-[2-[4-[(2,5-dichlorophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C23H25Cl2N3O
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0858844
|
4-isopropyl-6-((1-(2-(2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C29H35N3O3
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0377812
|
4-methyl-1-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]piperazin-2-one
Show/Hide
|
C29H36N4O2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0388750
|
1-[4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]piperidin-1-yl]ethanone
Show/Hide
|
C31H39N3O2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0386021
|
6-chloro-1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C26H27ClN4O
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0379189
|
2-(1-Benzenesulfonyl-1H-indol-4-yl)-ethylamine
Show/Hide
|
C16H16N2O2S
|
1
|
| 1 |
Ki = 4.5 nM
|
|
|
|
CP0503394
|
(S)-1-{2-[4-(4-Carbamoyl-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid methylamide
Show/Hide
|
C24H30N4O3
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0860616
|
3-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide
Show/Hide
|
C20H22ClN3O2S
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0380900
|
(8R)-8-[4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)butyl-propylamino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C27H37N3O3
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0404669
|
5-[2-[4-[(4-chloro-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C23H25ClN4O3
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0446892
|
1-methyl-5-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0448144
|
8-{[3-(3-Chloro-phenoxy)-propyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C25H29ClN2O2
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0404123
|
N,N-dimethyl-2-[6-(thian-4-yl)indol-1-yl]ethanamine
Show/Hide
|
C17H24N2S
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0201704
|
4-benzyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C32H34N4O3
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0465888
|
6-[2-[4-(2-methylquinolin-5-yl)oxypiperidin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H27N3O3
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0382052
|
5-[2-[4-[[3-(furan-3-yl)phenyl]methyl]piperidin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C28H30N2O2
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0416467
|
(8R)-8-[2-methylpropyl(propyl)amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C20H28N2O
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0280275
|
N,N-dimethyl-2-(6-thiophen-3-ylindol-1-yl)ethanamine
Show/Hide
|
C16H18N2S
|
1
|
| 1 |
Ki = 7.3 nM
|
|
|
|
CP0467378
|
N-(2-phenylethyl)-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C23H28N2
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0404695
|
5-[2-[4-[(4-fluoro-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C23H25FN4O3
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0423703
|
6-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]azetidin-3-yl]methoxy]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H25N3O4
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0388730
|
2-methyl-5-[2-[4-[(3-phenylphenyl)methyl]piperidin-1-yl]ethoxy]quinoline
Show/Hide
|
C30H32N2O
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0330654
|
2-[1-(benzenesulfonyl)indol-4-yl]-N,N-dimethylethanamine
Show/Hide
|
C18H20N2O2S
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
|
CP0376302
|
8-{[4-(4,4-Dimethyl-2,6-dioxo-piperidin-1-yl)-butyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C27H37N3O3
|
1
|
| 1 |
Ki = 9.8 nM
|
|
|
|
CP0446420
|
2-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]-7H-1,2-benzoxazin-6-one
Show/Hide
|
C25H28N4O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0446421
|
4-[[4-[2-(2-methylquinolin-5-yl)oxyethyl]piperazin-1-yl]methyl]-2-nitrophenol
Show/Hide
|
C23H26N4O4
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0897868
|
6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Show/Hide
|
C25H28N4O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0433939
|
6-[3-[4-(2-methylquinolin-5-yl)piperazin-1-yl]propyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0374348
|
1-methyl-4-[3-[[1-[2-(2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]phenyl]piperazin-2-one
Show/Hide
|
C29H36N4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0271827
|
(+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
Show/Hide
|
C14H18N2
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0433937
|
6-[4-[4-(2-methylquinolin-5-yl)piperazin-1-yl]butyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0422491
|
6-[2-[4-(2-phenylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C29H28N4O2
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0419374
|
N-[3-(3-chlorophenoxy)propyl]-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C24H29ClN2O
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0509166
|
N-propyl-N-(2-thiophen-2-ylethyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C21H26N2S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0064163
|
(8R)-N,N-dimethyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C14H18N2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0056626
|
(8R)-N,N-dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
|
C18H26N2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0380845
|
8-(Methyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C17H22N2O
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0480515
|
(8S)-8-(dimethylamino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
Show/Hide
|
C15H18N2O
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0495389
|
5-[2-[4-[(4-methoxy-3-nitrophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
|
C24H28N4O4
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0406074
|
1,6-dimethyl-5-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
|
C28H32N4O
|
1
|
| 1 |
Ki = 19.95 nM
|
|
|
|
CP0193325
|
2-[6-(3,6-dihydro-2H-thiopyran-4-yl)indol-1-yl]-N,N-dimethylethanamine
Show/Hide
|
C17H22N2S
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0428818
|
8-(Cyclopropylmethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C20H26N2O
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1
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| 1 |
Ki = 24 nM
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CP0398940
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6-[2-[(1R,4R)-5-(2-methylquinolin-5-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C25H26N4O2
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1
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| 1 |
Ki = 25.12 nM
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CP0378588
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4,4-Dimethyl-1-{4-[propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amino]-butyl}-piperidine-2,6-dione
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C26H37N3O2
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1
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| 1 |
Ki = 26 nM
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CP0448143
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8-Propylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C16H20N2O
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1
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| 1 |
Ki = 27 nM
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CP0873359
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2-Chloro-N-[3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-benzenesulfonamide
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C20H22ClN3O2S
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1
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| 1 |
Ki = 29.5 nM
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CP0308876
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2-[6-(3,6-dihydro-2H-pyran-4-yl)indol-1-yl]-N,N-dimethylethanamine
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C17H22N2O
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1
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| 1 |
Ki = 32 nM
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CP0401280
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8-(Benzyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde
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C23H26N2O
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1
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| 1 |
Ki = 33 nM
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CP0378469
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(8R)-N-(2-methylpropyl)-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C19H28N2
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1
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| 1 |
Ki = 35 nM
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CP0428161
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Allyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
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C18H24N2
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1
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| 1 |
Ki = 35 nM
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CP0258010
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(+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
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C18H26N2
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1
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| 1 |
Ki = 39 nM
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CP0406076
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1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperidin-1-yl]ethyl]quinolin-2-one
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C28H31N3O
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1
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| 1 |
Ki = 39.81 nM
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CP0357881
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N,N-dimethyl-2-(6-naphthalen-2-ylindol-1-yl)ethanamine
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C22H22N2
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1
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| 1 |
Ki = 57 nM
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CP0432290
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(3-Phenyl-propyl)-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-ylmethyl)-amine
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C22H26N2
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1
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| 1 |
Ki = 63 nM
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CP0461737
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6-[[1-[2-(8-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
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C26H28ClN3O3
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1
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| 1 |
Ki = 63.1 nM
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CP0777252
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2-Iodo-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide
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C20H22IN3O2S
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1
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| 1 |
Ki = 65 nM
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CP0382288
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N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C15H20N2
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1
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| 1 |
Ki = 69 nM
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CP0381324
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N-(cyclopropylmethyl)-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
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C19H26N2
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1
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| 1 |
Ki = 75 nM
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CP0376303
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8-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]indole
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C16H20N2
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1
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| 1 |
Ki = 77 nM
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CP0371948
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8-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
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C26H27F2N3O3
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1
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| 1 |
Ki = 79.43 nM
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CP0378357
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6-[[1-[2-(8-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H28FN3O3
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1
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| 1 |
Ki = 79.43 nM
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CP0465889
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6-[[1-[2-(2-methylquinolin-5-yl)oxypropyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C27H31N3O3
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1
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| 1 |
Ki = 79.43 nM
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CP0418991
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[1-(benzenesulfonyl)-4-[2-(dimethylamino)ethyl]indol-2-yl]-phenylmethanone
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C25H24N2O3S
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1
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| 1 |
Ki = 98 nM
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CP0183577
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5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid ((S)-3-hexahydro-pyrrolo[1,2-a]pyrazin-2-yl-4-methoxy-phenyl)-amide
Show/Hide
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C23H26ClN3O3S2
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1
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| 1 |
Ki = 100 nM
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CP0035199
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5-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H27F2N3O3
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1
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| 1 |
Ki = 100 nM
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CP0165719
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N-[3-[(8aR)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H26ClN3O3S2
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1
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| 1 |
Ki = 125.89 nM
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CP0441452
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6-[[4-(2-methylquinolin-5-yl)piperazin-1-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C23H24N4O2
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1
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| 1 |
Ki = 125.89 nM
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CP0339112
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4-phenyl-N-(4-piperazin-1-ylquinolin-6-yl)benzenesulfonamide
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C25H24N4O2S
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1
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| 1 |
Ki = 158.49 nM
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CP0433940
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6-[[1-[3-(2-methylquinolin-5-yl)oxypropyl]azetidin-3-yl]methoxy]-4H-1,4-benzoxazin-3-one
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C25H27N3O4
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1
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| 1 |
Ki = 158.49 nM
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CP0853819
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(E)-N-(2-Dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-acrylamide TFA
Show/Hide
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C37H40F3N3O3
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1
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| 1 |
Ki = 158.49 nM
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CP0405371
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N-methyl-N-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
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C16H22N2
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1
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| 1 |
Ki = 170 nM
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CP0409092
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[3-[2-(dimethylamino)ethyl]-5-hydroxyindol-1-yl]-phenylmethanone
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C19H20N2O2
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1
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| 1 |
Ki = 180 nM
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CP0428133
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Benzyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine
Show/Hide
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C22H26N2
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1
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| 1 |
Ki = 192 nM
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CP0113176
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5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Show/Hide
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C21H24ClN3O3S2
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1
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| 1 |
Ki = 199.53 nM
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CP0111551
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5-chloro-N-(4-piperazin-1-ylquinolin-6-yl)naphthalene-2-sulfonamide
Show/Hide
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C23H21ClN4O2S
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1
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| 1 |
Ki = 199.53 nM
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CP0044323
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(8S)-N,N-dimethyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
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C14H18N2
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1
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| 1 |
Ki = 228 nM
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CP0437569
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(8S)-8-[4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)butyl-propylamino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde;hydrate
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C27H37N3O3
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1
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| 1 |
Ki = 250 nM
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CP0185590
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4-Bromo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulfonamide
Show/Hide
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C18H22BrN3O3S
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1
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| 1 |
Ki = 251.19 nM
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CP0674190
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5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid (4-methoxy-3-piperazin-1-yl-phenyl)-amide hydrochloride
Show/Hide
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C20H23Cl2N3O3S2
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1
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| 1 |
Ki = 251.19 nM
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CP0306083
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5-chloro-3-methyl-N-[4-(4-methylpiperazin-1-yl)quinolin-6-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H23ClN4O2S2
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1
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| 1 |
Ki = 251.19 nM
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CP0041243
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5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride
Show/Hide
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C20H22ClN3O3S2
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1
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| 1 |
Ki = 251.19 nM
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CP0296883
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7-fluoro-6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H27F2N3O3
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1
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| 1 |
Ki = 251.19 nM
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CP0464205
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2-methyl-5-[2-[4-[(3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperidin-1-yl]ethoxy]quinoline-7-carbonitrile
Show/Hide
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C27H28N4O3
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1
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| 1 |
Ki = 251.19 nM
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CP0433938
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6-[2-[4-[(2-methylquinolin-5-yl)oxymethyl]piperidin-1-yl]acetyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H27N3O4
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1
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| 1 |
Ki = 251.19 nM
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CP0433941
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6-[1-[3-(2-methylquinolin-5-yl)oxypropyl]azetidin-3-yl]oxy-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H25N3O4
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1
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| 1 |
Ki = 251.19 nM
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CP0082421
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5-chloro-3-methyl-N-(2-methyl-4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H23ClN4O2S2
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1
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| 1 |
Ki = 316.23 nM
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CP0216543
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N-[3-(1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl)-4-methoxyphenyl]-5-chloro-3-methyl-1-benzothiophene-2-sulfonamide
Show/Hide
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C24H28ClN3O3S2
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1
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| 1 |
Ki = 316.23 nM
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CP0318039
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3-(2-Dimethylamino-ethyl)-1H-indole-2-carboxylic acid ethyl ester
Show/Hide
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C15H20N2O2
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1
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| 1 |
Ki = 330 nM
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CP0393050
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8-Azepan-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]indole
Show/Hide
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C18H24N2
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1
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| 1 |
Ki = 340 nM
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CP0208303
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5-chloro-2-methyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-3-sulfonamide
Show/Hide
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C22H21ClN4O2S2
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1
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| 1 |
Ki = 398.11 nM
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CP0343547
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5-chloro-3-methyl-N-[4-[(3S)-3-methylpiperazin-1-yl]quinolin-6-yl]-1-benzothiophene-2-sulfonamide
Show/Hide
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C23H23ClN4O2S2
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1
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| 1 |
Ki = 398.11 nM
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CP0507914
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6-[[1-[2-(7-fluoro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H28FN3O3
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1
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| 1 |
Ki = 398.11 nM
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CP0861232
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3-Cyclopentyl-N-(2-dimethylamino-ethyl)-N-[4'-(phenethylamino-methyl)-biphenyl-4-ylmethyl]-propionamide with di TFA
Show/Hide
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C38H47F6N3O5
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1
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| 1 |
Ki = 398.11 nM
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CP0388359
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N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]phenyl]-4-phenylbenzamide
Show/Hide
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C28H26ClN5O2
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1
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| 1 |
Ki = 416.87 nM
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CP0216619
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(8S)-N,N-dipropyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-amine
Show/Hide
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C18H26N2
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1
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| 1 |
Ki = 441 nM
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CP0388360
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N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
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C29H28ClN5O2
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1
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| 1 |
Ki = 457.09 nM
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CP0051242
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(R)-1-(2-(1-(3-bromo-benzenesulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
Show/Hide
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C18H27BrN2O2S
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1
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| 1 |
Ki = 501.19 nM
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CP0712961
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(R)-sulfonamide1-(4-methylhexahydro-1-pyridinyl)-2-[1-(1-naphthylsulfonyl)hexahydro-2-pyridinyl]ethane
Show/Hide
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C23H32N2O2S
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1
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| 1 |
Ki = 501.19 nM
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CP0255950
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2-[1-(benzenesulfonyl)indol-3-yl]-N,N-dimethylethanamine
Show/Hide
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C18H20N2O2S
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1
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| 1 |
Ki = 510 nM
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CP0198069
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(R)-4-Methyl-1-(2-(1-(naphthalene-1-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine(10)
Show/Hide
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C22H30N2O2S
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1
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| 1 |
Ki = 630.96 nM
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CP0271460
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(R)-1-(2-(1-(3,4-Dichloro-benzene sulfonyl)-pyrrolidin-2-yl)-ethyl)-4-methyl piperidine
Show/Hide
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C18H26Cl2N2O2S
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1
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| 1 |
Ki = 630.96 nM
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CP0173778
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5-chloro-3-methyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
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C22H21ClN4O2S2
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1
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| 1 |
Ki = 630.96 nM
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CP0295528
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6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-5-fluoro-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H27ClFN3O3
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1
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| 1 |
Ki = 630.96 nM
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CP0332841
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6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-8-fluoro-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H27ClFN3O3
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1
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| 1 |
Ki = 630.96 nM
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CP0045069
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2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-N,N-dimethylethanamine
Show/Hide
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C19H22N2O3S
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1
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| 1 |
Ki = 720 nM
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CP0399906
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N-[5-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Show/Hide
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C29H28ClN5O2
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1
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| 1 |
Ki = 741.31 nM
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CP0332842
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6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-7-fluoro-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H27ClFN3O3
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1
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| 1 |
Ki = 794.33 nM
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CP0495740
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6-[[1-[2-(7-chloro-2-methylquinolin-5-yl)oxyethyl]piperidin-4-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C26H28ClN3O3
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1
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| 1 |
Ki = 794.33 nM
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CP0081712
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4-tert-butyl-N-(4-piperazin-1-ylquinolin-6-yl)benzenesulfonamide
Show/Hide
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C23H28N4O2S
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1
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| 1 |
Ki = 1258.93 nM
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CP0433935
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6-[[4-[(2-methylquinolin-5-yl)oxymethyl]piperidin-1-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C25H27N3O3
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1
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| 1 |
Ki = 1258.93 nM
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CP0526143
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6-[[4-(2-methylquinolin-5-yl)oxypiperidin-1-yl]methyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H25N3O3
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1
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| 1 |
Ki = 1258.93 nM
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CP0847634
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(E)-N-[4'-(Phenethylamino-methyl)-biphenyl-4-ylmethyl]-3-phenyl-N-pyridin-3-ylmethyl-acrylamide TFA
Show/Hide
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C39H36F3N3O3
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1
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| 1 |
Ki = 1258.93 nM
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CP0096286
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(R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol
Show/Hide
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C18H28N2O3S
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1
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| 1 |
Ki = 1584.89 nM
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CP0658944
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(RS)-1-(4-methylhexahydro-1-pyridinyl)-2-[1-(1-naphthylsulfonyl)hexahydro-2-pyridinyl]ethane
Show/Hide
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C23H32N2O2S
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1
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| 1 |
Ki = 1995.26 nM
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CP0433950
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6-[2-[4-(2-methylquinolin-5-yl)oxypiperidin-1-yl]acetyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C25H25N3O4
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1
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| 1 |
Ki = 1995.26 nM
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CP0170807
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5-chloro-3-ethyl-N-(4-piperazin-1-ylquinolin-6-yl)-1-benzothiophene-2-sulfonamide
Show/Hide
|
C23H23ClN4O2S2
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1
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| 1 |
Ki = 2511.89 nM
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CP0404672
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5-[2-[4-[(3,4-dichlorophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
Show/Hide
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C23H25Cl2N3O
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1
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| 1 |
Ki = 2511.89 nM
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CP0156235
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3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide
Show/Hide
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C18H30N2O2S
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1
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| 1 |
Ki = 3162.28 nM
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CP0182705
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(R)-4-Methyl-1-(2-(1-toluene-3-sulfonyl)-pyrrolidin-2-yl)-ethyl)-piperidine (Oxalate salt)
Show/Hide
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C19H30N2O2S
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1
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| 1 |
Ki = 3162.28 nM
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CP0186950
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(4S,5S)-4-Dimethylamino-1-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-benzo[cd]indol-5-ol
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C20H22N2O3S
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1
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| 1 |
Ki = 3900 nM
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CP0853639
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2-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide
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C19H20ClN3O2S
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1
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| 1 |
Ki > 1000 nM
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CP0437527
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5-[2-[(2S)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1,6-dimethylquinolin-2-one
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C28H31FN4O
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1
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| 1 |
Ki > 1000 nM
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CP0485418
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5-[2-[4-[(2,6-dichlorophenyl)methyl]piperazin-1-yl]ethoxy]-2-methylquinoline
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C23H25Cl2N3O
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1
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| 1 |
Ki < 10000 nM
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