Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(3-{4-[2-(4-Fluoro-phenyl)-ethyl]-piperazin-1-yl}-propyl)-5-[1,2,4]triazol-4-yl-1H-indole
    Show/Hide
 PubChem ID
CID: 10574762
SID: 15602889
Canonical SMILES
Fc1ccc(CCN2CCN(CCCc3c[nH]c4ccc(cc34)-n3cnnc3)CC2)cc1
    Show/Hide
Compound Formula C25H29FN6
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 1D
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28221
Gene Name
HTR1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 1.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.8 nM
   TI
   LI
   LO
   TS