Brief Information of the Compound and Protein
Compound Name
N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine
    Show/Hide
PubChem ID
CID: 5078
SID: 15221855
Canonical SMILES
CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12
    Show/Hide
Compound Formula C15H19N5
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1D
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28221
Gene Name
HTR1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 8.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.3 nM
2 Ki = 13.5 nM
3 Ki = 40 nM