Brief Information of the Compound and Protein
Compound Name
3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-5-[1,2,4]triazol-4-yl-1H-indole
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PubChem ID
CID: 10614906
SID: 15645114
Canonical SMILES
CN1CCN(CCc2c[nH]c3ccc(cc23)-n2cnnc2)CC1
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Compound Formula C17H22N6
Compound Structure
Protein Name
5-hydroxytryptamine receptor 1D
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28221
Gene Name
HTR1D
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  4
1
EC50 = 80 nM
   TI
   LI
   LO
   TS
2
EC50 = 105 nM
   TI
   LI
   LO
   TS
3
IC50 = 134 nM
   TI
   LI
   LO
   TS
4
IC50 = 140 nM
   TI
   LI
   LO
   TS